{"id":"https://openalex.org/W4282964698","doi":"https://doi.org/10.1016/s0016-5085(22)60242-7","title":"443: COLORECTAL CANCER-ASSOCIATED BACTERIAL GENES ARE WIDELY ENCODED IN HUMAN MICROBIOMES","display_name":"443: COLORECTAL CANCER-ASSOCIATED BACTERIAL GENES ARE WIDELY ENCODED IN HUMAN MICROBIOMES","publication_year":2022,"publication_date":"2022-05-01","ids":{"openalex":"https://openalex.org/W4282964698","doi":"https://doi.org/10.1016/s0016-5085(22)60242-7"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(22)60242-7","doi":"https://doi.org/10.1016/s0016-5085(22)60242-7","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(22)60242-7","pdf_url":"http://www.gastrojournal.org/article/S0016508522602427/pdf","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.gastrojournal.org/article/S0016508522602427/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082949276","display_name":"Samuel S. Minot","orcid":"https://orcid.org/0000-0003-1639-3905","observed_orcids":["https://orcid.org/0000-0003-1639-3905"]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel S. Minot","raw_affiliation_strings":["Data Core, Fred Hutchinson Cancer Center; Seattle, WA","Microbiome Research Initiative, Fred Hutchinson Cancer Center; Seattle, WA","Research Tech],","Scientist, Hutch Bioinformatics Core],"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Data Core, Fred Hutchinson Cancer Center; Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Microbiome Research Initiative, Fred Hutchinson Cancer Center; Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Research Tech],","institution_ids":[]},{"raw_affiliation_string":"Scientist, Hutch Bioinformatics Core],","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066878858","display_name":"Naisi Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Naisi Li","raw_affiliation_strings":["Fred Hutchinson Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fred Hutchinson Cancer Center","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076202468","display_name":"Sean T. Koester","orcid":"https://orcid.org/0000-0002-0984-2752","observed_orcids":["https://orcid.org/0000-0002-0984-2752"]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sean T. Koester","raw_affiliation_strings":["Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center; Seattle, WA","Research Tech],","Scientist, Hutch Bioinformatics Core],"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center; Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Research Tech],","institution_ids":[]},{"raw_affiliation_string":"Scientist, Hutch Bioinformatics Core],","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ming Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ming Yu","raw_affiliation_strings":["Research Tech],","Scientist, Hutch Bioinformatics Core],","Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center; Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Tech],","institution_ids":[]},{"raw_affiliation_string":"Scientist, Hutch Bioinformatics Core],","institution_ids":[]},{"raw_affiliation_string":"Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center; Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068477057","display_name":"William M. Grady","orcid":"https://orcid.org/0000-0002-0129-7809","observed_orcids":["https://orcid.org/0000-0002-0129-7809"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William M. Grady","raw_affiliation_strings":["Department of Medicine, Division of Gastroenterology, University of Washington; Seattle, WA","Research Tech],","Scientist, Hutch Bioinformatics Core],","Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center; Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Gastroenterology, University of Washington; Seattle, WA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Research Tech],","institution_ids":[]},{"raw_affiliation_string":"Scientist, Hutch Bioinformatics Core],","institution_ids":[]},{"raw_affiliation_string":"Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center; Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047126443","display_name":"Jason A. Dominitz","orcid":"https://orcid.org/0000-0002-8070-7086","observed_orcids":["https://orcid.org/0000-0002-8070-7086"]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason A. Dominitz","raw_affiliation_strings":["Department of Medicine, Division of Gastroenterology, University of Washington; Seattle, WA","National Gastroenterology and Hepatology Program, U.S. Department of Veterans Affairs; Seattle, WA","Research Tech],","Scientist, Hutch Bioinformatics Core],"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Gastroenterology, University of Washington; Seattle, WA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"National Gastroenterology and Hepatology Program, U.S. Department of Veterans Affairs; Seattle, WA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]},{"raw_affiliation_string":"Research Tech],","institution_ids":[]},{"raw_affiliation_string":"Scientist, Hutch Bioinformatics Core],","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030095493","display_name":"Neelendu Dey","orcid":"https://orcid.org/0000-0001-8825-5689","observed_orcids":["https://orcid.org/0000-0001-8825-5689"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Neelendu Dey","raw_affiliation_strings":["Department of Laboratory Medicine and Pathology, University of Washington; Seattle, WA","Department of Medicine, Division of Gastroenterology, University of Washington; Seattle, WA","Microbiome Research Initiative, Fred Hutchinson Cancer Center; Seattle, WA","Research Tech],","Scientist, Hutch Bioinformatics Core],","Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center; Seattle, WA","[Graduate student],"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology, University of Washington; Seattle, WA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Medicine, Division of Gastroenterology, University of Washington; Seattle, WA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Microbiome Research Initiative, Fred Hutchinson Cancer Center; Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Research Tech],","institution_ids":[]},{"raw_affiliation_string":"Scientist, Hutch Bioinformatics Core],","institution_ids":[]},{"raw_affiliation_string":"Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center; Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"[Graduate student],","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5030095493"],"corresponding_institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05354744,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"162","issue":"7","first_page":"S","last_page":"96"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9919999837875366},{"id":"https://openalex.org/keywords/bacterial-genes","display_name":"bacterial genes","score":0.7680000066757202},{"id":"https://openalex.org/keywords/human-microbiome","display_name":"human microbiome","score":0.9739999771118164},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.7450000047683716},{"id":"https://openalex.org/keywords/cancer-genes","display_name":"cancer genes","score":0.5789999961853027}],"concepts":[{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.8638896942138672},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6852872967720032},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5685842633247375},{"id":"https://openalex.org/C91478284","wikidata":"https://www.wikidata.org/wiki/Q6623796","display_name":"Human microbiome","level":3,"score":0.5231627225875854},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4895935654640198},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46742507815361023},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.44917744398117065},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3070010244846344}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0016-5085(22)60242-7","doi":"https://doi.org/10.1016/s0016-5085(22)60242-7","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(22)60242-7","pdf_url":"http://www.gastrojournal.org/article/S0016508522602427/pdf","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/s0016-5085(22)60242-7","doi":"https://doi.org/10.1016/s0016-5085(22)60242-7","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(22)60242-7","pdf_url":"http://www.gastrojournal.org/article/S0016508522602427/pdf","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4282964698.pdf","grobid_xml":"https://content.openalex.org/works/W4282964698.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1978709058","https://openalex.org/W1987375206","https://openalex.org/W2001561488","https://openalex.org/W2018348035","https://openalex.org/W2043179057","https://openalex.org/W2057041675","https://openalex.org/W2072492789","https://openalex.org/W2089643849","https://openalex.org/W2104593962","https://openalex.org/W2130410032","https://openalex.org/W2130725058","https://openalex.org/W2131026689","https://openalex.org/W2162667876","https://openalex.org/W2170551349","https://openalex.org/W2178425989","https://openalex.org/W2179438025","https://openalex.org/W2507494997","https://openalex.org/W2890582054","https://openalex.org/W2913649454","https://openalex.org/W2927453907","https://openalex.org/W2949004447","https://openalex.org/W2965005210","https://openalex.org/W2965836614","https://openalex.org/W2967074377","https://openalex.org/W2971593808","https://openalex.org/W2991429913","https://openalex.org/W3087640284","https://openalex.org/W3099862724","https://openalex.org/W3128646645","https://openalex.org/W3158359541","https://openalex.org/W3158873216","https://openalex.org/W3203123631","https://openalex.org/W4200439800","https://openalex.org/W4224095926","https://openalex.org/W4254268441","https://openalex.org/W4292004337","https://openalex.org/W4297933854","https://openalex.org/W6685184340","https://openalex.org/W7074137041"],"related_works":["https://openalex.org/W4403265017","https://openalex.org/W3003845906","https://openalex.org/W7160427243","https://openalex.org/W7132113450","https://openalex.org/W3005430855","https://openalex.org/W2765664791","https://openalex.org/W4327676933","https://openalex.org/W7160333217","https://openalex.org/W7208203046","https://openalex.org/W3211755932"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-06-17T00:00:00"}