{"id":"https://openalex.org/W4282960809","doi":"https://doi.org/10.1158/1538-7445.am2022-26","title":"Abstract 26: Influence of geographic/ancestral origin on glioma incidence and outcomes in US Hispanics","display_name":"Abstract 26: Influence of geographic/ancestral origin on glioma incidence and outcomes in US Hispanics","publication_year":2022,"publication_date":"2022-06-15","ids":{"openalex":"https://openalex.org/W4282960809","doi":"https://doi.org/10.1158/1538-7445.am2022-26"},"language":"en","primary_location":{"id":"doi:10.1158/1538-7445.am2022-26","doi":"https://doi.org/10.1158/1538-7445.am2022-26","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.am2022-26","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050523491","display_name":"Kyle M. Walsh","orcid":"https://orcid.org/0000-0002-5879-9981","observed_orcids":["https://orcid.org/0000-0002-5879-9981"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyle M. Walsh","raw_affiliation_strings":["1Duke University School of Medicine, Durham, NC;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Duke University School of Medicine, Durham, NC;","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014655558","display_name":"Corey Neff","orcid":"https://orcid.org/0000-0001-9479-2747","observed_orcids":["https://orcid.org/0000-0001-9479-2747"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Corey Neff","raw_affiliation_strings":["1Duke University School of Medicine, Durham, NC;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Duke University School of Medicine, Durham, NC;","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012085802","display_name":"Melissa L. Bondy","orcid":"https://orcid.org/0000-0002-0278-414X","observed_orcids":["https://orcid.org/0000-0002-0278-414X"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melissa L. Bondy","raw_affiliation_strings":["2Stanford University School of Medicine, Palo Alto, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Stanford University School of Medicine, Palo Alto, CA;","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078384857","display_name":"Carol A. Kruchko","orcid":"https://orcid.org/0000-0001-7212-035X","observed_orcids":["https://orcid.org/0000-0001-7212-035X"]},"institutions":[{"id":"https://openalex.org/I4210129234","display_name":"Central Brain Tumor Registry of the United States","ror":"https://ror.org/03849s113","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210129234"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carol Kruchko","raw_affiliation_strings":["3Central Brain Tumor Registry of the United States, Hinsdale, IL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Central Brain Tumor Registry of the United States, Hinsdale, IL;","institution_ids":["https://openalex.org/I4210129234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024476694","display_name":"Jason T. Huse","orcid":"https://orcid.org/0000-0003-4514-0640","observed_orcids":["https://orcid.org/0000-0003-4514-0640"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason T. Huse","raw_affiliation_strings":["4The University of Texas MD Anderson Cancer Center, Houston, TX;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4The University of Texas MD Anderson Cancer Center, Houston, TX;","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028989565","display_name":"Christopher Ian Amos","orcid":"https://orcid.org/0000-0002-8540-7023","observed_orcids":["https://orcid.org/0000-0002-8540-7023"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher I. Amos","raw_affiliation_strings":["5Baylor College of Medicine, Houston, TX;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"5Baylor College of Medicine, Houston, TX;","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051948022","display_name":"Jill S. Barnholtz\u2010Sloan","orcid":"https://orcid.org/0000-0001-6190-9304","observed_orcids":["https://orcid.org/0000-0001-6190-9304"]},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jill S. Barnholtz-Sloan","raw_affiliation_strings":["6National Cancer Institute, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"6National Cancer Institute, Bethesda, MD","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014071257","display_name":"Quinn T. Ostrom","orcid":"https://orcid.org/0000-0003-3469-7558","observed_orcids":["https://orcid.org/0000-0003-3469-7558"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Quinn T. Ostrom","raw_affiliation_strings":["1Duke University School of Medicine, Durham, NC;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Duke University School of Medicine, Durham, NC;","institution_ids":["https://openalex.org/I170897317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"82","issue":"12_Supplement","first_page":"26","last_page":"26"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.6362000107765198,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.6362000107765198,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening","score":0.36010000109672546,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glioma","display_name":"glioma","score":0.984000027179718},{"id":"https://openalex.org/keywords/hispanic-americans","display_name":"Hispanic Americans","score":0.6579999923706055},{"id":"https://openalex.org/keywords/geographical-origin","display_name":"geographical origin","score":0.6439999938011169},{"id":"https://openalex.org/keywords/ancestral-origins","display_name":"ancestral origins","score":0.8040000200271606},{"id":"https://openalex.org/keywords/glioblastoma","display_name":"glioblastoma","score":0.8220000267028809},{"id":"https://openalex.org/keywords/oligodendroglioma","display_name":"oligodendroglioma","score":0.9829999804496765},{"id":"https://openalex.org/keywords/ependymoma","display_name":"ependymoma","score":0.9850000143051147},{"id":"https://openalex.org/keywords/pilocytic-astrocytoma","display_name":"pilocytic astrocytoma","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cancer-incidence","display_name":"cancer incidence","score":0.5789999961853027},{"id":"https://openalex.org/keywords/cancer-survival","display_name":"cancer survival","score":0.953000009059906},{"id":"https://openalex.org/keywords/european-admixture","display_name":"European admixture","score":0.753000020980835},{"id":"https://openalex.org/keywords/african-admixture","display_name":"African admixture","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ethnic-disparities","display_name":"ethnic disparities","score":0.3540000021457672},{"id":"https://openalex.org/keywords/county-level-analysis","display_name":"county-level analysis","score":0.5619999766349792}],"concepts":[{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.789044201374054},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.6554298996925354},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6542038321495056},{"id":"https://openalex.org/C2778227246","wikidata":"https://www.wikidata.org/wiki/Q1365309","display_name":"Glioma","level":2,"score":0.6487704515457153},{"id":"https://openalex.org/C147077947","wikidata":"https://www.wikidata.org/wiki/Q1515895","display_name":"Socioeconomic status","level":3,"score":0.5552816987037659},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.5439280867576599},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5392808318138123},{"id":"https://openalex.org/C77350462","wikidata":"https://www.wikidata.org/wiki/Q1125472","display_name":"Confounding","level":2,"score":0.4997708797454834},{"id":"https://openalex.org/C2778527826","wikidata":"https://www.wikidata.org/wiki/Q1787017","display_name":"Cancer registry","level":3,"score":0.4871813654899597},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.4181058406829834},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20904657244682312},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.1424025595188141},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1538-7445.am2022-26","doi":"https://doi.org/10.1158/1538-7445.am2022-26","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.am2022-26","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/10","score":0.7578999996185303,"display_name":"Reduced inequalities"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4286615514","https://openalex.org/W3215406370","https://openalex.org/W2808979164","https://openalex.org/W4416141070","https://openalex.org/W2952126206","https://openalex.org/W2899807471","https://openalex.org/W7140783057","https://openalex.org/W2767710989","https://openalex.org/W2767384197","https://openalex.org/W2980007602"],"abstract_inverted_index":{"Abstract":[0],"PURPOSE:":[1],"Glioma":[2,284],"is":[3,15,34],"the":[4,30,63,69,76,98,132,292,296,330,385],"most":[5],"common":[6],"type":[7],"of":[8,68,80,97,101,105,114,194,262,295,301,311,336,370,384],"primary":[9],"malignant":[10],"brain":[11],"tumor,":[12],"and":[13,37,43,72,104,116,157,173,211,221,223,252,264,276,286,309,333,376],"incidence":[14,42,53,134,139,275,285,375],"25%":[16],"lower":[17,191,231],"in":[18,27,55,119,181,219,247,267,289,326,378],"U.S.":[19,31,56,337],"Hispanics":[20,57,120,179,185,245,338,380],"than":[21,244],"White":[22],"non-Hispanics.":[23],"Though":[24],"often":[25],"pooled":[26],"epidemiological":[28],"analyses,":[29],"Hispanic":[32,99,234,297],"population":[33,100],"very":[35],"diverse,":[36],"registry-based":[38],"analyses":[39],"may":[40],"mask":[41],"survival":[44,73,243,253],"differences":[45,135,254],"associated":[46,272,279],"with":[47,269,273,280,291,299],"geographic/ancestral":[48,371],"origins.":[49],"METHODS:":[50],"County-level":[51,138],"glioma":[52,133,195,232,374],"data":[54,74,90],"from":[58,62,75,123,186,237],"2000-2017":[59],"were":[60,91,121,162,217],"retrieved":[61],"Central":[64],"Brain":[65],"Tumor":[66],"Registry":[67],"United":[70],"States,":[71],"CDC\u2019s":[77],"National":[78],"Program":[79],"Cancer":[81,389,400],"Registries":[82],"was":[83,140],"obtained":[84,122],"for":[85,147,388],"2001-2017.":[86],"American":[87,386],"Community":[88],"Survey":[89],"used":[92,163],"to":[93,145,164,178],"determine":[94],"county-level":[95,170],"proportion":[96],"Mexican/Central-American":[102],"origin":[103,107,171,372],"Caribbean":[106],"(Puerto":[108],"Rican,":[109],"Cuban,":[110],"Dominican).":[111],"State-level":[112],"estimates":[113,261],"European":[115,263,270],"African":[117,265,277],"admixture":[118,266,271,278],"published":[124],"23andMe":[125],"data.":[126],"Incidence":[127,251],"rate":[128],"ratios":[129],"(IRRs)":[130],"quantified":[131],"across":[136],"groups.":[137],"modeled":[141],"using":[142,224],"linear":[143],"regression":[144],"control":[146],"potential":[148],"confounding":[149],"factors":[150],"(e.g.,":[151],"county":[152],"size,":[153],"median":[154],"socioeconomic":[155],"status),":[156],"Cox":[158],"proportional":[159],"hazards":[160],"models":[161],"assess":[165],"associations":[166],"between":[167],"individual-level":[168],"survival,":[169],"percentages,":[172],"state-level":[174,260],"admixture.":[175],"RESULTS:":[176],"Compared":[177],"living":[180,246],"predominantly":[182,187,238,248,302],"Caribbean-origin":[183,249,312],"counties,":[184],"Mexican/Central-American-origin":[188,239,303],"counties":[189,240,304,313],"had":[190,241],"age-adjusted":[192],"risks":[193],"(IRR=0.83;":[196],"P<0.0001),":[197,200,204,207],"glioblastoma":[198,235],"(IRR=0.86;":[199],"diffuse/anaplastic":[201],"astrocytoma":[202,213],"(IRR=0.78;":[203],"oligodendroglioma":[205],"(IRR=0.82;":[206],"ependymoma":[208],"(IRR=0.88;":[209],"P=0.012),":[210],"pilocytic":[212],"(IRR=0.76;":[214],"P<0.0001).":[215],"Associations":[216],"consistent":[218],"children":[220],"adults,":[222],"more":[225],"granular":[226],"geographic":[227,293],"regions.":[228],"Despite":[229],"having":[230],"incidence,":[233],"patients":[236],"poorer":[242],"counties.":[250],"could":[255],"be":[256],"partially":[257],"explained":[258],"by":[259],"Hispanics,":[268],"higher":[274],"improved":[281],"survival.":[282],"CONCLUSIONS:":[283],"outcomes":[287,377],"differ":[288],"association":[290],"origins":[294],"community,":[298],"residents":[300],"at":[305,314],"significantly":[306],"reduced":[307],"risk":[308],"those":[310],"comparatively":[315],"greater":[316],"risk.":[317],"Although":[318],"typically":[319],"classified":[320],"as":[321],"a":[322],"single":[323],"ethnic":[324],"group":[325],"registry":[327],"data,":[328],"appreciating":[329],"cultural,":[331],"socioeconomic,":[332],"genetic":[334],"diversity":[335],"will":[339],"help":[340],"advance":[341],"cancer":[342],"disparities":[343],"research.":[344],"Citation":[345],"Format:":[346],"Kyle":[347],"M.":[348],"Walsh,":[349],"Corey":[350],"Neff,":[351],"Melissa":[352],"L.":[353],"Bondy,":[354],"Carol":[355],"Kruchko,":[356],"Jason":[357],"T.":[358,367],"Huse,":[359],"Christopher":[360],"I.":[361],"Amos,":[362],"Jill":[363],"S.":[364],"Barnholtz-Sloan,":[365],"Quinn":[366],"Ostrom.":[368],"Influence":[369],"on":[373],"US":[379],"[abstract].":[381],"In:":[382],"Proceedings":[383],"Association":[387],"Research":[390],"Annual":[391],"Meeting":[392],"2022;":[393],"2022":[394],"Apr":[395],"8-13.":[396],"Philadelphia":[397],"(PA):":[398],"AACR;":[399],"Res":[401],"2022;82(12_Suppl):Abstract":[402],"nr":[403],"26.":[404]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2022-06-17T00:00:00"}