{"id":"https://openalex.org/W4282945868","doi":"https://doi.org/10.1016/j.bone.2022.116471","title":"Low bone mass and impaired fracture healing in mouse models of Trisomy21 (Down syndrome)","display_name":"Low bone mass and impaired fracture healing in mouse models of Trisomy21 (Down syndrome)","publication_year":2022,"publication_date":"2022-06-15","ids":{"openalex":"https://openalex.org/W4282945868","doi":"https://doi.org/10.1016/j.bone.2022.116471","pmid":"https://pubmed.ncbi.nlm.nih.gov/35716916","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9356441"},"language":"en","primary_location":{"id":"doi:10.1016/j.bone.2022.116471","doi":"https://doi.org/10.1016/j.bone.2022.116471","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bone.2022.116471","pdf_url":null,"source":{"id":"https://openalex.org/S121725775","display_name":"Bone","issn_l":"1873-2763","issn":["1873-2763","8756-3282"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Bone","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.bone.2022.116471","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021281678","display_name":"Kirby M. Sherman","orcid":"https://orcid.org/0000-0002-4167-1973","observed_orcids":["https://orcid.org/0000-0002-4167-1973"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kirby M. Sherman","raw_affiliation_strings":["Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005757834","display_name":"Diarra K Williams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diarra K. Williams","raw_affiliation_strings":["Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075739162","display_name":"Casey A. Welsh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Casey A. Welsh","raw_affiliation_strings":["Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073467545","display_name":"Alexis Cooper","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexis M. Cooper","raw_affiliation_strings":["Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018547938","display_name":"Alyssa  R. Falck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alyssa Falck","raw_affiliation_strings":["Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019228014","display_name":"Shannon S. Huggins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shannon Huggins","raw_affiliation_strings":["Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022487543","display_name":"Rihana S. Bokhari","orcid":"https://orcid.org/0000-0002-9248-4449","observed_orcids":["https://orcid.org/0000-0002-9248-4449"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rihana S. Bokhari","raw_affiliation_strings":["Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091482075","display_name":"Dana Gaddy","orcid":"https://orcid.org/0000-0001-7685-1766","observed_orcids":["https://orcid.org/0000-0001-7685-1766"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dana Gaddy","raw_affiliation_strings":["Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066586533","display_name":"Kent D. McKelvey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kent D. McKelvey","raw_affiliation_strings":["Department of Family Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States of America; Department of Medical Genetics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States of America","Department of Family Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States of America","Department of Medical Genetics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Family Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States of America; Department of Medical Genetics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States of America","institution_ids":["https://openalex.org/I79620101"]},{"raw_affiliation_string":"Department of Family Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States of America","institution_ids":["https://openalex.org/I79620101"]},{"raw_affiliation_string":"Department of Medical Genetics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States of America","institution_ids":["https://openalex.org/I79620101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051378797","display_name":"Lindsay Dawson","orcid":"https://orcid.org/0000-0002-4903-6050","observed_orcids":["https://orcid.org/0000-0002-4903-6050"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lindsay A. Dawson","raw_affiliation_strings":["Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042599014","display_name":"Larry J. Suva","orcid":"https://orcid.org/0000-0002-2892-9757","observed_orcids":["https://orcid.org/0000-0002-2892-9757"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Larry J. Suva","raw_affiliation_strings":["Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America. Electronic address: larry-suva@tamu.edu","Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America. Electronic address: larry-suva@tamu.edu","institution_ids":["https://openalex.org/I91045830"]},{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, United States of America","institution_ids":["https://openalex.org/I91045830"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5042599014"],"corresponding_institution_ids":["https://openalex.org/I91045830"],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":null,"fwci":2.207,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.86658858,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"162","issue":null,"first_page":"116471","last_page":"116471"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11015","display_name":"Down syndrome and intellectual disability research","score":0.9556000232696533,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11015","display_name":"Down syndrome and intellectual disability research","score":0.9556000232696533,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.033900000154972076,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/down-syndrome","display_name":"Down syndrome","score":0.996999979019165},{"id":"https://openalex.org/keywords/osteopenia","display_name":"osteopenia","score":0.8740000128746033},{"id":"https://openalex.org/keywords/impaired-fracture-healing","display_name":"impaired fracture healing","score":0.7889999747276306},{"id":"https://openalex.org/keywords/ts65dn-mice","display_name":"Ts65Dn mouse model","score":0.6809999942779541},{"id":"https://openalex.org/keywords/sex-differences-in-bone","display_name":"sex differences in bone","score":0.6010000109672546},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.6930000185966492},{"id":"https://openalex.org/keywords/reproductive-hormones","display_name":"reproductive hormones","score":0.6610000133514404},{"id":"https://openalex.org/keywords/testosterone","display_name":"testosterone","score":0.8399999737739563},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-gonadal-axis","display_name":"hypothalamic-pituitary-gonadal axis","score":0.9330000281333923},{"id":"https://openalex.org/keywords/callus-formation","display_name":"callus formation","score":0.7269999980926514},{"id":"https://openalex.org/keywords/skeletal-abnormalities","display_name":"skeletal abnormalities","score":0.5529999732971191}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6473977565765381},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6310886740684509},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.6075690388679504},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5695438385009766},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.5640199184417725},{"id":"https://openalex.org/C2777083390","wikidata":"https://www.wikidata.org/wiki/Q1367706","display_name":"Osteopenia","level":4,"score":0.5474130511283875},{"id":"https://openalex.org/C8337478","wikidata":"https://www.wikidata.org/wiki/Q1777289","display_name":"Bone healing","level":2,"score":0.4827408194541931},{"id":"https://openalex.org/C2781245598","wikidata":"https://www.wikidata.org/wiki/Q5182134","display_name":"Craniofacial","level":2,"score":0.48161906003952026},{"id":"https://openalex.org/C2779329777","wikidata":"https://www.wikidata.org/wiki/Q2304401","display_name":"Bone density","level":3,"score":0.4509550631046295},{"id":"https://openalex.org/C2780712178","wikidata":"https://www.wikidata.org/wiki/Q25326559","display_name":"Peak bone mass","level":4,"score":0.44993355870246887},{"id":"https://openalex.org/C2777871287","wikidata":"https://www.wikidata.org/wiki/Q7502090","display_name":"Short stature","level":2,"score":0.4431014657020569},{"id":"https://openalex.org/C105083479","wikidata":"https://www.wikidata.org/wiki/Q181497","display_name":"Sexual dimorphism","level":2,"score":0.4388730227947235},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.3555174469947815},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33054569363594055},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.17345848679542542},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004314","descriptor_name":"Down Syndrome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004314","descriptor_name":"Down Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005640","descriptor_name":"Follicle Stimulating Hormone","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017102","descriptor_name":"Fracture Healing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.bone.2022.116471","doi":"https://doi.org/10.1016/j.bone.2022.116471","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bone.2022.116471","pdf_url":null,"source":{"id":"https://openalex.org/S121725775","display_name":"Bone","issn_l":"1873-2763","issn":["1873-2763","8756-3282"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Bone","raw_type":"journal-article"},{"id":"pmid:35716916","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35716916","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9356441","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9356441","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Bone","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.bone.2022.116471","doi":"https://doi.org/10.1016/j.bone.2022.116471","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bone.2022.116471","pdf_url":null,"source":{"id":"https://openalex.org/S121725775","display_name":"Bone","issn_l":"1873-2763","issn":["1873-2763","8756-3282"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Bone","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5970891241","display_name":"Investigating injury response and bone regeneration in Down syndrome mouse models","funder_award_id":"F31HD110287","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G6779117969","display_name":"Modeling Odontohypophosphatasia in the Sheep","funder_award_id":"R21DE028076","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G9000859988","display_name":"Veterinary Medical Student Research Training","funder_award_id":"T35OD010991","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000884058","display_name":"Understanding the skeleton in Down Syndrome","funder_award_id":"R01HD102909","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320333551","display_name":"College of Veterinary Medicine and Biomedical Sciences, Texas A and M University","ror":null},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":70,"referenced_works":["https://openalex.org/W120272052","https://openalex.org/W172772731","https://openalex.org/W1505308024","https://openalex.org/W1575011814","https://openalex.org/W1600239095","https://openalex.org/W1751673191","https://openalex.org/W1910322641","https://openalex.org/W1982451886","https://openalex.org/W1987252938","https://openalex.org/W1997381668","https://openalex.org/W1997482243","https://openalex.org/W2000353984","https://openalex.org/W2006124071","https://openalex.org/W2010782320","https://openalex.org/W2014640240","https://openalex.org/W2016662879","https://openalex.org/W2025782007","https://openalex.org/W2037454811","https://openalex.org/W2038769797","https://openalex.org/W2066749771","https://openalex.org/W2075544506","https://openalex.org/W2079860207","https://openalex.org/W2084087844","https://openalex.org/W2093228291","https://openalex.org/W2096425957","https://openalex.org/W2096452264","https://openalex.org/W2097323692","https://openalex.org/W2100061591","https://openalex.org/W2102940020","https://openalex.org/W2107220991","https://openalex.org/W2115587655","https://openalex.org/W2129736783","https://openalex.org/W2138298735","https://openalex.org/W2142121353","https://openalex.org/W2164216363","https://openalex.org/W2166179667","https://openalex.org/W2169631945","https://openalex.org/W2201478822","https://openalex.org/W2231321683","https://openalex.org/W2243582477","https://openalex.org/W2306947905","https://openalex.org/W2411107431","https://openalex.org/W2727340347","https://openalex.org/W2748010327","https://openalex.org/W2761369644","https://openalex.org/W2770273625","https://openalex.org/W2789489527","https://openalex.org/W2790176262","https://openalex.org/W2792384449","https://openalex.org/W2792839668","https://openalex.org/W2886762065","https://openalex.org/W2944961582","https://openalex.org/W2956607278","https://openalex.org/W2971489145","https://openalex.org/W2987603503","https://openalex.org/W2998617730","https://openalex.org/W3016275894","https://openalex.org/W3017329003","https://openalex.org/W3025843910","https://openalex.org/W3037987616","https://openalex.org/W3047068534","https://openalex.org/W3049706505","https://openalex.org/W3092836247","https://openalex.org/W3144828512","https://openalex.org/W3188355793","https://openalex.org/W3194852178","https://openalex.org/W4237822883","https://openalex.org/W4245408774","https://openalex.org/W4300609576","https://openalex.org/W6630227459"],"related_works":["https://openalex.org/W2987603503","https://openalex.org/W4405364476","https://openalex.org/W2079860207","https://openalex.org/W3016275894","https://openalex.org/W4391597010","https://openalex.org/W2096452264","https://openalex.org/W2998617730","https://openalex.org/W6902765998","https://openalex.org/W4414300585","https://openalex.org/W1974025476"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-06-16T00:00:00"}