{"id":"https://openalex.org/W4282944845","doi":"https://doi.org/10.1097/01.hjh.0000835624.65401.d5","title":"IMPORTANCE OF URIC ACID THRESHOLD IN ITS CORRELATION WITH METABOLIC SYNDROME","display_name":"IMPORTANCE OF URIC ACID THRESHOLD IN ITS CORRELATION WITH METABOLIC SYNDROME","publication_year":2022,"publication_date":"2022-06-01","ids":{"openalex":"https://openalex.org/W4282944845","doi":"https://doi.org/10.1097/01.hjh.0000835624.65401.d5"},"language":"en","primary_location":{"id":"doi:10.1097/01.hjh.0000835624.65401.d5","doi":"https://doi.org/10.1097/01.hjh.0000835624.65401.d5","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.hjh.0000835624.65401.d5","pdf_url":null,"source":{"id":"https://openalex.org/S115964404","display_name":"Journal of Hypertension","issn_l":"0263-6352","issn":["0263-6352","1473-5598"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hypertension","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081703642","display_name":"Alessandro Maloberti","orcid":"https://orcid.org/0000-0002-2612-6264","observed_orcids":["https://orcid.org/0000-0002-2612-6264"]},"institutions":[{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandro Maloberti","raw_affiliation_strings":["Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY","institution_ids":["https://openalex.org/I4210094195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007589838","display_name":"Ilaria Garofani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ilaria Garofani","raw_affiliation_strings":["School of Medicine and Surgery, University of Milano-Bicocca, Milan, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine and Surgery, University of Milano-Bicocca, Milan, ITALY","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080377110","display_name":"Stefano Fumagalli","orcid":"https://orcid.org/0000-0002-6950-3875","observed_orcids":["https://orcid.org/0000-0002-6950-3875"]},"institutions":[{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stefano Fumagalli","raw_affiliation_strings":["School of Medicine and Surgery, University of Milano-Bicocca, Milan, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine and Surgery, University of Milano-Bicocca, Milan, ITALY","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042412983","display_name":"Claudio Mario Ciampi","orcid":"https://orcid.org/0000-0002-1285-8464","observed_orcids":["https://orcid.org/0000-0002-1285-8464"]},"institutions":[{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Claudio Mario Ciampi","raw_affiliation_strings":["Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY","institution_ids":["https://openalex.org/I4210094195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033725179","display_name":"Paolo Ossola","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo Ossola","raw_affiliation_strings":["Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY","institution_ids":["https://openalex.org/I4210094195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034438794","display_name":"Marco Carbonaro","orcid":"https://orcid.org/0009-0003-1603-6147","observed_orcids":["https://orcid.org/0009-0003-1603-6147"]},"institutions":[{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marco Carbonaro","raw_affiliation_strings":["Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY","institution_ids":["https://openalex.org/I4210094195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083516210","display_name":"Massimiliano Monticelli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimiliano Monticelli","raw_affiliation_strings":["Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY","institution_ids":["https://openalex.org/I4210094195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059945154","display_name":"Giovanni Tavecchia","orcid":"https://orcid.org/0000-0003-3358-8050","observed_orcids":["https://orcid.org/0000-0003-3358-8050"]},"institutions":[{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giovanni Tavecchia","raw_affiliation_strings":["Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY","institution_ids":["https://openalex.org/I4210094195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065859301","display_name":"Michele Bombelli","orcid":"https://orcid.org/0000-0002-8459-711X","observed_orcids":["https://orcid.org/0000-0002-8459-711X"]},"institutions":[{"id":"https://openalex.org/I4210152301","display_name":"Azienda Ospedaliera di Desio e Vimercate","ror":"https://ror.org/055redd10","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210152301"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Michele Bombelli","raw_affiliation_strings":["Internal Medicine Department, Desio, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine Department, Desio, ITALY","institution_ids":["https://openalex.org/I4210152301"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054501501","display_name":"Cristina Giannattasio","orcid":"https://orcid.org/0000-0001-9116-3494","observed_orcids":["https://orcid.org/0000-0001-9116-3494"]},"institutions":[{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Cristina Giannattasio","raw_affiliation_strings":["Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology 4, A. De Gasperis Cardio Center, ASST GOM Niguarda Ca Granda, Milan, ITALY","institution_ids":["https://openalex.org/I4210094195"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"40","issue":"Suppl 1","first_page":"e42","last_page":"e42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11139","display_name":"Gout, Hyperuricemia, Uric Acid","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11139","display_name":"Gout, Hyperuricemia, Uric Acid","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12964","display_name":"Diet, Metabolism, and Disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serum-uric-acid","display_name":"serum uric acid","score":0.949999988079071},{"id":"https://openalex.org/keywords/hyperuricemia","display_name":"hyperuricemia","score":0.9750000238418579},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.953000009059906},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.8700000047683716},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.8859999775886536},{"id":"https://openalex.org/keywords/atp-iii-criteria","display_name":"NCEP ATP III criteria","score":0.8659999966621399},{"id":"https://openalex.org/keywords/cardiovascular-risk-stratification","display_name":"cardiovascular risk stratification","score":0.38499999046325684}],"concepts":[{"id":"https://openalex.org/C2779721657","wikidata":"https://www.wikidata.org/wiki/Q49970","display_name":"Hyperuricemia","level":3,"score":0.9728864431381226},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9068607091903687},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.7528790831565857},{"id":"https://openalex.org/C2779881121","wikidata":"https://www.wikidata.org/wiki/Q105522","display_name":"Uric acid","level":2,"score":0.7471481561660767},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6155591607093811},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.5411478877067566},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.458874374628067},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4122650921344757},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3628693222999573},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.10825154185295105},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.05672672390937805},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1097/01.hjh.0000835624.65401.d5","doi":"https://doi.org/10.1097/01.hjh.0000835624.65401.d5","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.hjh.0000835624.65401.d5","pdf_url":null,"source":{"id":"https://openalex.org/S115964404","display_name":"Journal of Hypertension","issn_l":"0263-6352","issn":["0263-6352","1473-5598"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hypertension","raw_type":"journal-article"},{"id":"pmh:oai:boa.unimib.it:10281/391308","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/10281/391308","pdf_url":null,"source":{"id":"https://openalex.org/S4306401259","display_name":"BOA (University of Milano-Bicocca)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I66752286","host_organization_name":"University of Milano-Bicocca","host_organization_lineage":["https://openalex.org/I66752286"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:boa.unimib.it:10281/412878","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/10281/412878","pdf_url":null,"source":{"id":"https://openalex.org/S4306401259","display_name":"BOA (University of Milano-Bicocca)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I66752286","host_organization_name":"University of Milano-Bicocca","host_organization_lineage":["https://openalex.org/I66752286"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4280540112","https://openalex.org/W4402312523","https://openalex.org/W2386225430","https://openalex.org/W2361501518","https://openalex.org/W2363181652","https://openalex.org/W2357043315","https://openalex.org/W4200140763","https://openalex.org/W2270226971","https://openalex.org/W2887668138","https://openalex.org/W7220602625"],"abstract_inverted_index":{"Objective:":[0],"The":[1,276],"relationship":[2],"between":[3,17,87],"Hyperuricemia":[4,149,173,192,207,258,284,298],"and":[5,22,90,103,124,185,193,200,227],"Cardiovascular":[6],"risk":[7],"has":[8,52],"been":[9,54],"established":[10],"but":[11],"whether":[12,34,59],"or":[13,42],"not":[14,53],"a":[15,29,44,66,80],"correlation":[16,86],"Serum":[18],"Uric":[19],"Acid":[20],"(SUA)":[21],"Metabolic":[23],"Syndrome":[24],"(MS)":[25],"exists":[26],"is":[27,37,244,279,299],"still":[28],"matter":[30],"of":[31,39,47,70,82,136,164,178,204,312],"debate.":[32],"Indeed":[33],"SUA":[35,91,144,243],"level":[36],"part":[38],"MS":[40,63,88,167,194,212,247,263,302],"diagnosis":[41,89,163,248,303],"just":[43],"pure":[45],"marker":[46],"an":[48],"unfavourable":[49],"metabolic":[50],"profile":[51],"demonstrated.":[55],"Besides":[56],"it's":[57],"unknown":[58],"SUA's":[60],"addition":[61],"to":[62,153,181,188,246,262],"definition":[64],"makes":[65],"difference":[67],"in":[68,79,142,170,176,196,211,214],"terms":[69],"prognosis.":[71],"In":[72],"our":[73],"study":[74],"we":[75],"focused":[76],"on":[77],"evaluating":[78],"group":[81],"hypertensive":[83],"patients,":[84],"the":[85,120,133,154,182,205,267,288,308],"defined":[92,265,286,306,310],"with":[93,148,301],"two":[94,155],"different":[95,156],"cut-off:":[96],"1)":[97],">":[98,104,111],"6":[99],"mg/dL":[100,113,226],"for":[101,106,114,162,223,234],"women":[102],"7":[105],"men":[107],"(classic":[108],"cut-off);":[109],"2)":[110],"5.6":[112,236,313],"both":[115],"sexes":[116],"(recently":[117],"proposed":[118],"by":[119,132,266,287,307],"URRAH":[121,189],"Project).":[122],"Design":[123],"method:":[125],"We":[126],"enrolled":[127],"473":[128],"Hypertensive":[129],"patients":[130],"followed":[131],"Hypertension":[134],"Unit":[135],"San":[137],"Gerardo":[138],"Hospital":[139],"(Monza,":[140],"Italy),":[141],"which":[143],"was":[145,168,174,208,259,285],"measured.":[146],"Patients":[147],"were":[150,160],"identified":[151],"according":[152,180,187],"thresholds.":[157],"NCEP-ATP-III":[158],"criteria":[159],"used":[161],"MS.":[165],"Results:":[166],"diagnosed":[169],"33.6%":[171],"while":[172],"found":[175],"14.8%":[177],"subjects":[179,216],"traditional":[183],"cut-off":[184,224,235,269,290,311],"35.9%":[186],"study's":[190],"cut-off.":[191],"coexist":[195],"9.7%":[197],"(traditional":[198],"cut-off)":[199],"17.3%":[201],"(URRAH's":[202],"threshold)":[203],"population.":[206],"more":[209],"frequent":[210],"than":[213],"non-MS":[215],"(29":[217],"vs":[218,229],"7.6%,":[219],"p-value":[220,231,252,273,294],"<":[221,232,253,274,295],"0.0001":[222,233],"6/7":[225],"51.6":[228],"28.0%,":[230],"mg/dL).":[237],"Linear":[238],"regression":[239],"models":[240],"showed":[241],"that":[242],"related":[245,261,300],"(\u03b2":[249],"=":[250,271,292],"1.597,":[251],"0.0001).":[254,275,296],"At":[255],"logistic":[256],"analysis":[257],"strongly":[260],"when":[264,283,305],"HURRAH's":[268],"(OR":[270,291],"0.303,":[272],"same":[277],"relation":[278],"weak,":[280],"although":[281],"significan,":[282],"classic":[289],"0.182,":[293],"Conclusions:":[297],"especially":[304],"recently":[309],"mg/dL.":[314]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2022-06-16T00:00:00"}