{"id":"https://openalex.org/W4282919522","doi":"https://doi.org/10.1158/2643-3230.bcd-21-0075","title":"Follicular Lymphoma Microenvironment Characteristics Associated with Tumor Cell Mutations and MHC Class II Expression","display_name":"Follicular Lymphoma Microenvironment Characteristics Associated with Tumor Cell Mutations and MHC Class II Expression","publication_year":2022,"publication_date":"2022-06-10","ids":{"openalex":"https://openalex.org/W4282919522","doi":"https://doi.org/10.1158/2643-3230.bcd-21-0075","pmid":"https://pubmed.ncbi.nlm.nih.gov/35687817"},"language":"en","primary_location":{"id":"doi:10.1158/2643-3230.bcd-21-0075","doi":"https://doi.org/10.1158/2643-3230.bcd-21-0075","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2643-3230.bcd-21-0075","pdf_url":null,"source":{"id":"https://openalex.org/S4210239195","display_name":"Blood Cancer Discovery","issn_l":"2643-3230","issn":["2643-3230","2643-3249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Cancer Discovery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1158/2643-3230.bcd-21-0075","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042517430","display_name":"Guangchun Han","orcid":"https://orcid.org/0000-0001-9277-2507","observed_orcids":["https://orcid.org/0000-0001-9277-2507"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guangchun Han","raw_affiliation_strings":["1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0001-9277-2507","affiliations":[{"raw_affiliation_string":"1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072335941","display_name":"Qing Deng","orcid":"https://orcid.org/0000-0001-5116-461X","observed_orcids":["https://orcid.org/0000-0001-5116-461X"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qing Deng","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0001-5116-461X","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068406191","display_name":"Mario Luiz Marques-Piubelli","orcid":"https://orcid.org/0000-0002-6324-2096","observed_orcids":["https://orcid.org/0000-0002-6324-2096"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mario L. Marques-Piubelli","raw_affiliation_strings":["3Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0002-6324-2096","affiliations":[{"raw_affiliation_string":"3Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002868490","display_name":"Enyu Dai","orcid":"https://orcid.org/0000-0001-5836-0277","observed_orcids":["https://orcid.org/0000-0001-5836-0277"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Enyu Dai","raw_affiliation_strings":["1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0001-5836-0277","affiliations":[{"raw_affiliation_string":"1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067812785","display_name":"Minghao Dang","orcid":"https://orcid.org/0000-0001-7287-2877","observed_orcids":["https://orcid.org/0000-0001-7287-2877"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Minghao Dang","raw_affiliation_strings":["1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0001-7287-2877","affiliations":[{"raw_affiliation_string":"1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020448123","display_name":"Man Chun John Ma","orcid":"https://orcid.org/0000-0002-2000-8144","observed_orcids":["https://orcid.org/0000-0002-2000-8144"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Man Chun John Ma","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0002-2000-8144","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016101372","display_name":"Xubin Li","orcid":"https://orcid.org/0000-0003-1727-9215","observed_orcids":["https://orcid.org/0000-0003-1727-9215"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xubin Li","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0003-1727-9215","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026939161","display_name":"Haopeng Yang","orcid":"https://orcid.org/0000-0002-3870-2679","observed_orcids":["https://orcid.org/0000-0002-3870-2679"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haopeng Yang","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0002-3870-2679","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038988779","display_name":"Jared M. Henderson","orcid":"https://orcid.org/0000-0002-5121-5234","observed_orcids":["https://orcid.org/0000-0002-5121-5234"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jared Henderson","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0002-5121-5234","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103213101","display_name":"Olga M. Kudryashova","orcid":"https://orcid.org/0000-0003-3320-7764","observed_orcids":["https://orcid.org/0000-0003-3320-7764"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Olga Kudryashova","raw_affiliation_strings":["4BostonGene Corporation, Waltham, Massachusetts"],"raw_orcid":"https://orcid.org/0000-0003-3320-7764","affiliations":[{"raw_affiliation_string":"4BostonGene Corporation, Waltham, Massachusetts","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038333464","display_name":"Mark Meerson","orcid":"https://orcid.org/0000-0002-3495-9370","observed_orcids":["https://orcid.org/0000-0002-3495-9370"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark Meerson","raw_affiliation_strings":["4BostonGene Corporation, Waltham, Massachusetts"],"raw_orcid":"https://orcid.org/0000-0002-3495-9370","affiliations":[{"raw_affiliation_string":"4BostonGene Corporation, Waltham, Massachusetts","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073202427","display_name":"Sergey V. Isaev","orcid":"https://orcid.org/0000-0002-0404-9261","observed_orcids":["https://orcid.org/0000-0002-0404-9261"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sergey Isaev","raw_affiliation_strings":["4BostonGene Corporation, Waltham, Massachusetts"],"raw_orcid":"https://orcid.org/0000-0002-0404-9261","affiliations":[{"raw_affiliation_string":"4BostonGene Corporation, Waltham, Massachusetts","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090334093","display_name":"Nikita Kotlov","orcid":"https://orcid.org/0000-0002-6393-7357","observed_orcids":["https://orcid.org/0000-0002-6393-7357"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nikita Kotlov","raw_affiliation_strings":["4BostonGene Corporation, Waltham, Massachusetts"],"raw_orcid":"https://orcid.org/0000-0002-6393-7357","affiliations":[{"raw_affiliation_string":"4BostonGene Corporation, Waltham, Massachusetts","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015633466","display_name":"Krystle J. Nomie","orcid":"https://orcid.org/0000-0002-3479-8247","observed_orcids":["https://orcid.org/0000-0002-3479-8247"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Krystle J. Nomie","raw_affiliation_strings":["4BostonGene Corporation, Waltham, Massachusetts"],"raw_orcid":"https://orcid.org/0000-0002-3479-8247","affiliations":[{"raw_affiliation_string":"4BostonGene Corporation, Waltham, Massachusetts","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045749988","display_name":"Alexander Bagaev","orcid":"https://orcid.org/0000-0002-8680-854X","observed_orcids":["https://orcid.org/0000-0002-8680-854X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alexander Bagaev","raw_affiliation_strings":["4BostonGene Corporation, Waltham, Massachusetts"],"raw_orcid":"https://orcid.org/0000-0002-8680-854X","affiliations":[{"raw_affiliation_string":"4BostonGene Corporation, Waltham, Massachusetts","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043477787","display_name":"Edwin Roger Parra","orcid":"https://orcid.org/0000-0001-9068-1636","observed_orcids":["https://orcid.org/0000-0001-9068-1636"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edwin R. Parra","raw_affiliation_strings":["5Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0001-9068-1636","affiliations":[{"raw_affiliation_string":"5Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079077130","display_name":"Luisa M. Solis Soto","orcid":"https://orcid.org/0000-0002-1253-630X","observed_orcids":["https://orcid.org/0000-0002-1253-630X"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luisa M. Solis Soto","raw_affiliation_strings":["5Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0002-1253-630X","affiliations":[{"raw_affiliation_string":"5Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026422612","display_name":"Simrit Parmar","orcid":"https://orcid.org/0000-0003-1798-9233","observed_orcids":["https://orcid.org/0000-0003-1798-9233"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Simrit Parmar","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0003-1798-9233","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006742031","display_name":"Fredrick B. Hagemeister","orcid":"https://orcid.org/0000-0002-8788-7243","observed_orcids":["https://orcid.org/0000-0002-8788-7243"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fredrick B. Hagemeister","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0002-8788-7243","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039574726","display_name":"Sairah Ahmed","orcid":"https://orcid.org/0000-0001-7302-8299","observed_orcids":["https://orcid.org/0000-0001-7302-8299"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sairah Ahmed","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0001-7302-8299","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027071793","display_name":"Swaminathan P. Iyer","orcid":"https://orcid.org/0000-0002-1646-813X","observed_orcids":["https://orcid.org/0000-0002-1646-813X"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Swaminathan P. Iyer","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0002-1646-813X","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070455368","display_name":"Felipe Samaniego","orcid":"https://orcid.org/0000-0001-6931-4583","observed_orcids":["https://orcid.org/0000-0001-6931-4583"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Felipe Samaniego","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0001-6931-4583","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010407419","display_name":"Raphael Eric Steiner","orcid":"https://orcid.org/0000-0003-3717-3629","observed_orcids":["https://orcid.org/0000-0003-3717-3629"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raphael Steiner","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0003-3717-3629","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028677309","display_name":"Luis Fayad","orcid":"https://orcid.org/0000-0002-1844-5548","observed_orcids":["https://orcid.org/0000-0002-1844-5548"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luis Fayad","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0002-1844-5548","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024844183","display_name":"Hun Ju Lee","orcid":"https://orcid.org/0000-0001-7219-5562","observed_orcids":["https://orcid.org/0000-0001-7219-5562"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hun Lee","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0001-7219-5562","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044284041","display_name":"Nathan Hale Fowler","orcid":"https://orcid.org/0000-0002-9494-1877","observed_orcids":["https://orcid.org/0000-0002-9494-1877"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nathan H. Fowler","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","4BostonGene Corporation, Waltham, Massachusetts"],"raw_orcid":"https://orcid.org/0000-0002-9494-1877","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"4BostonGene Corporation, Waltham, Massachusetts","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082892912","display_name":"Christopher R. Flowers","orcid":"https://orcid.org/0000-0002-9524-3990","observed_orcids":["https://orcid.org/0000-0002-9524-3990"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher R. Flowers","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0002-9524-3990","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038196228","display_name":"Paolo Strati","orcid":"https://orcid.org/0000-0002-7445-1459","observed_orcids":["https://orcid.org/0000-0002-7445-1459"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paolo Strati","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0002-7445-1459","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021496101","display_name":"Jason R. Westin","orcid":"https://orcid.org/0000-0002-1824-2337","observed_orcids":["https://orcid.org/0000-0002-1824-2337"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason R. Westin","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0002-1824-2337","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064752432","display_name":"Sattva Swarup Neelapu","orcid":"https://orcid.org/0000-0003-1045-4914","observed_orcids":["https://orcid.org/0000-0003-1045-4914"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sattva S. Neelapu","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0003-1045-4914","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037878906","display_name":"Loretta J. Nastoupil","orcid":"https://orcid.org/0000-0001-6071-8610","observed_orcids":["https://orcid.org/0000-0001-6071-8610"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Loretta J. Nastoupil","raw_affiliation_strings":["2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0001-6071-8610","affiliations":[{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006947975","display_name":"Francisco Vega","orcid":"https://orcid.org/0000-0001-5956-452X","observed_orcids":["https://orcid.org/0000-0001-5956-452X"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Francisco Vega","raw_affiliation_strings":["3Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0001-5956-452X","affiliations":[{"raw_affiliation_string":"3Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051182441","display_name":"Linghua Wang","orcid":"https://orcid.org/0000-0001-9380-0266","observed_orcids":["https://orcid.org/0000-0001-9380-0266"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Linghua Wang","raw_affiliation_strings":["1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas","6UTHealth Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0001-9380-0266","affiliations":[{"raw_affiliation_string":"1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"6UTHealth Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":null,"display_name":"Michael R. Green","orcid":"https://orcid.org/0000-0001-6309-9472","observed_orcids":["https://orcid.org/0000-0001-6309-9472"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael R. Green","raw_affiliation_strings":["1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas","2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","6UTHealth Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas","7Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":"https://orcid.org/0000-0001-6309-9472","affiliations":[{"raw_affiliation_string":"1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"6UTHealth Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"7Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5051182441"],"corresponding_institution_ids":["https://openalex.org/I1343551460"],"apc_list":null,"apc_paid":null,"fwci":12.281,"has_fulltext":false,"cited_by_count":100,"citation_normalized_percentile":{"value":0.9932057,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"3","issue":"5","first_page":"428","last_page":"443"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/follicular-lymphoma","display_name":"follicular lymphoma","score":1.0},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mhc-class-ii-expression","display_name":"MHC class II expression","score":0.8920000195503235},{"id":"https://openalex.org/keywords/somatic-mutations","display_name":"somatic mutations","score":0.8669999837875366},{"id":"https://openalex.org/keywords/tumor-infiltrating-t-cells","display_name":"tumor-infiltrating T cells","score":0.8500000238418579},{"id":"https://openalex.org/keywords/cytotoxic-cd4-t-cells","display_name":"cytotoxic CD4+ T cells","score":0.996999979019165},{"id":"https://openalex.org/keywords/lymphoma-subtypes","display_name":"lymphoma subtypes","score":0.8019999861717224},{"id":"https://openalex.org/keywords/immune-checkpoint","display_name":"immune checkpoint","score":0.8830000162124634},{"id":"https://openalex.org/keywords/b-cell-lymphoma","display_name":"B-cell lymphoma","score":0.5640000104904175},{"id":"https://openalex.org/keywords/immunotherapy-targets","display_name":"immunotherapy targets","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6728569269180298},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.6493539214134216},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.5253750085830688},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.4929311275482178},{"id":"https://openalex.org/C170627219","wikidata":"https://www.wikidata.org/wiki/Q13218497","display_name":"MHC class I","level":4,"score":0.49069082736968994},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.4860968589782715},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4836386442184448},{"id":"https://openalex.org/C2777058707","wikidata":"https://www.wikidata.org/wiki/Q123251","display_name":"Follicular lymphoma","level":3,"score":0.46101275086402893},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.4556998014450073},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.45118600130081177},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4462531507015228},{"id":"https://openalex.org/C2778814158","wikidata":"https://www.wikidata.org/wiki/Q959350","display_name":"MHC class II","level":4,"score":0.4391588866710663},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.42692792415618896},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.37972337007522583},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.35887402296066284},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.20147714018821716},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20039412379264832},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.12429144978523254},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.06970340013504028},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008224","descriptor_name":"Lymphoma, Follicular","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008224","descriptor_name":"Lymphoma, Follicular","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008224","descriptor_name":"Lymphoma, Follicular","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008224","descriptor_name":"Lymphoma, Follicular","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1158/2643-3230.bcd-21-0075","doi":"https://doi.org/10.1158/2643-3230.bcd-21-0075","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2643-3230.bcd-21-0075","pdf_url":null,"source":{"id":"https://openalex.org/S4210239195","display_name":"Blood Cancer Discovery","issn_l":"2643-3230","issn":["2643-3230","2643-3249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Cancer Discovery","raw_type":"journal-article"},{"id":"pmid:35687817","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35687817","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood cancer discovery","raw_type":"Editorial"},{"id":"pmh:oai:pubmedcentral.nih.gov:9894575","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9894575","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Blood Cancer Discov","raw_type":"Text"},{"id":"pmh:oai:digitalcommons.library.tmc.edu:uthgsbs_docs-4820","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.library.tmc.edu/uthgsbs_docs/3915","pdf_url":null,"source":{"id":"https://openalex.org/S4377196655","display_name":"Digital Commons-TMC (Texas Medical Center)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1337852284","host_organization_name":"Texas Medical Center","host_organization_lineage":["https://openalex.org/I1337852284"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Faculty, Staff and Student Publications","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1158/2643-3230.bcd-21-0075","doi":"https://doi.org/10.1158/2643-3230.bcd-21-0075","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2643-3230.bcd-21-0075","pdf_url":null,"source":{"id":"https://openalex.org/S4210239195","display_name":"Blood Cancer Discovery","issn_l":"2643-3230","issn":["2643-3230","2643-3249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Cancer Discovery","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.6000000238418579,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G111615301","display_name":null,"funder_award_id":"P30 CA-016672","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G1276655881","display_name":null,"funder_award_id":"R01CA201380","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2929408662","display_name":null,"funder_award_id":"1372-21","funder_id":"https://openalex.org/F4320308295","funder_display_name":"Leukemia and Lymphoma Society"}],"funders":[{"id":"https://openalex.org/F4320308295","display_name":"Leukemia and Lymphoma Society","ror":"https://ror.org/04m0xav37"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":76,"referenced_works":["https://openalex.org/W1506890399","https://openalex.org/W1968797324","https://openalex.org/W1970060763","https://openalex.org/W1973878786","https://openalex.org/W1978152737","https://openalex.org/W2010369997","https://openalex.org/W2022866101","https://openalex.org/W2029525307","https://openalex.org/W2050231360","https://openalex.org/W2054076276","https://openalex.org/W2092503047","https://openalex.org/W2119180969","https://openalex.org/W2128313210","https://openalex.org/W2130189838","https://openalex.org/W2130579933","https://openalex.org/W2132598458","https://openalex.org/W2148687964","https://openalex.org/W2152162065","https://openalex.org/W2155943701","https://openalex.org/W2159707944","https://openalex.org/W2163401417","https://openalex.org/W2165229668","https://openalex.org/W2166170465","https://openalex.org/W2170654913","https://openalex.org/W2256016639","https://openalex.org/W2323326409","https://openalex.org/W2335435690","https://openalex.org/W2531449940","https://openalex.org/W2561792671","https://openalex.org/W2581681907","https://openalex.org/W2599601523","https://openalex.org/W2600132724","https://openalex.org/W2624831627","https://openalex.org/W2739338441","https://openalex.org/W2745713794","https://openalex.org/W2762226752","https://openalex.org/W2770335132","https://openalex.org/W2786224778","https://openalex.org/W2786672974","https://openalex.org/W2789039113","https://openalex.org/W2789925257","https://openalex.org/W2794480084","https://openalex.org/W2800392236","https://openalex.org/W2887034336","https://openalex.org/W2897249806","https://openalex.org/W2898830231","https://openalex.org/W2899145148","https://openalex.org/W2902226821","https://openalex.org/W2904120187","https://openalex.org/W2906738980","https://openalex.org/W2912552280","https://openalex.org/W2917252593","https://openalex.org/W2942610007","https://openalex.org/W2949177718","https://openalex.org/W2949237386","https://openalex.org/W2961217357","https://openalex.org/W2970789858","https://openalex.org/W2984472267","https://openalex.org/W3000215297","https://openalex.org/W3002780060","https://openalex.org/W3032968363","https://openalex.org/W3035551042","https://openalex.org/W3036371068","https://openalex.org/W3081625447","https://openalex.org/W3083613542","https://openalex.org/W3128501672","https://openalex.org/W3138983672","https://openalex.org/W3149640503","https://openalex.org/W3159506065","https://openalex.org/W3162215872","https://openalex.org/W3199943451","https://openalex.org/W4232939899","https://openalex.org/W4394666350","https://openalex.org/W6674561012","https://openalex.org/W6748816842","https://openalex.org/W6800717233"],"related_works":["https://openalex.org/W1840653008","https://openalex.org/W2977793531","https://openalex.org/W2023967363","https://openalex.org/W1939527068","https://openalex.org/W2154173448","https://openalex.org/W2126139339","https://openalex.org/W2168688111","https://openalex.org/W2070684866","https://openalex.org/W4281625971","https://openalex.org/W4362567252"],"abstract_inverted_index":{"Follicular":[0],"lymphoma":[1],"(FL)":[2],"is":[3,13,159,194],"a":[4,8,45,114],"B-cell":[5],"malignancy":[6],"with":[7,56,99,123,161,179],"complex":[9],"tumor":[10,28,137,162],"microenvironment":[11,120],"that":[12,72,158,175],"rich":[14],"in":[15,102,121,196],"nonmalignant":[16],"immune":[17,30,170],"cells.":[18,87,111],"We":[19,50,142],"applied":[20],"single-cell":[21],"RNA":[22],"sequencing":[23],"to":[24],"characterize":[25],"the":[26,103,118,145,197],"diverse":[27],"and":[29,35,105,126,129,165],"cell":[31,138],"populations":[32],"of":[33,40,62,91,109,117,168],"FL":[34,41,54,86,95,119,124],"identified":[36,149,166],"major":[37,53],"phenotypic":[38],"subsets":[39],"T":[42,110,147,152,173],"cells,":[43,148],"including":[44],"cytotoxic":[46,150],"CD4":[47,151],"T-cell":[48,64],"population.":[49],"characterized":[51,144],"four":[52],"subtypes":[55],"differential":[57],"representation":[58],"or":[59],"relative":[60],"depletion":[61],"distinct":[63],"subsets.":[65],"By":[66],"integrating":[67],"exome":[68],"sequencing,":[69],"we":[70],"observed":[71],"somatic":[73],"mutations":[74],"are":[75],"associated":[76,98,160],"with,":[77],"but":[78],"not":[79],"definitive":[80],"for,":[81],"reduced":[82],"MHC":[83,127,183],"expression":[84,90],"on":[85,172],"In":[88,198],"turn,":[89],"MHCII":[92,139],"genes":[93],"by":[94,188],"cells":[96,153,174],"was":[97],"significant":[100],"differences":[101],"proportions":[104],"targetable":[106,169],"immunophenotypic":[107],"characteristics":[108],"This":[112,192,199],"provides":[113],"classification":[115],"framework":[116],"association":[122],"genotypes":[125],"expression,":[128],"informs":[130],"different":[131],"potential":[132],"immunotherapeutic":[133],"strategies":[134],"based":[135],"upon":[136],"expression.":[140,184],"SIGNIFICANCE:":[141],"have":[143],"FL-infiltrating":[146],"as":[154],"an":[155],"important":[156],"component":[157],"cell-intrinsic":[163],"characteristics,":[164],"sets":[167],"checkpoints":[171],"differed":[176],"from":[177],"FLs":[178],"normal":[180],"versus":[181],"low":[182],"See":[185],"related":[186],"commentary":[187],"Melnick,":[189],"p.":[190,202],"374.":[191],"article":[193],"highlighted":[195],"Issue":[200],"feature,":[201],"369.":[203]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":26},{"year":2024,"cited_by_count":31},{"year":2023,"cited_by_count":23},{"year":2022,"cited_by_count":7}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}