{"id":"https://openalex.org/W4282821557","doi":"https://doi.org/10.3390/ani12121529","title":"Effects of Pasteurella multocida on Histopathology, miRNA and mRNA Expression Dynamics in Lung of Goats","display_name":"Effects of Pasteurella multocida on Histopathology, miRNA and mRNA Expression Dynamics in Lung of Goats","publication_year":2022,"publication_date":"2022-06-13","ids":{"openalex":"https://openalex.org/W4282821557","doi":"https://doi.org/10.3390/ani12121529","pmid":"https://pubmed.ncbi.nlm.nih.gov/35739866","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9219503"},"language":"en","primary_location":{"id":"doi:10.3390/ani12121529","doi":"https://doi.org/10.3390/ani12121529","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ani12121529","pdf_url":"https://www.mdpi.com/2076-2615/12/12/1529/pdf?version=1655791849","source":{"id":"https://openalex.org/S4210168508","display_name":"Animals","issn_l":"2076-2615","issn":["2076-2615"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animals","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2076-2615/12/12/1529/pdf?version=1655791849","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067111051","display_name":"Wencan Zhang","orcid":"https://orcid.org/0000-0001-8657-2883","observed_orcids":["https://orcid.org/0000-0001-8657-2883"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wencan Zhang","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044243482","display_name":"Zizhuo Jiao","orcid":"https://orcid.org/0009-0006-5976-1578","observed_orcids":["https://orcid.org/0009-0006-5976-1578"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zizhuo Jiao","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Huixian Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huixian Huang","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yanru Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanru Wu","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071832001","display_name":"Haotian Wu","orcid":"https://orcid.org/0000-0002-6271-0249","observed_orcids":["https://orcid.org/0000-0002-6271-0249","https://orcid.org/0000-0002-4765-1623","https://orcid.org/0000-0003-2137-6907"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haotian Wu","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zhiyong Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiyong Liu","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100605418","display_name":"Zhenxing Zhang","orcid":"https://orcid.org/0000-0002-3205-5909","observed_orcids":["https://orcid.org/0000-0002-3205-5909"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhenxing Zhang","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":"https://orcid.org/0000-0002-3205-5909","affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100774643","display_name":"Qi An","orcid":"https://orcid.org/0000-0002-7361-6856","observed_orcids":["https://orcid.org/0000-0002-7361-6856"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi An","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024113299","display_name":"Yiwen Cheng","orcid":"https://orcid.org/0000-0003-3255-5425","observed_orcids":["https://orcid.org/0000-0003-3255-5425","https://orcid.org/0000-0003-3095-9311"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiwen Cheng","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100366182","display_name":"Si Chen","orcid":"https://orcid.org/0000-0002-0435-1954","observed_orcids":["https://orcid.org/0000-0002-0435-1954","https://orcid.org/0000-0003-4442-9450"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Si Chen","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001631794","display_name":"Churiga Man","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Churiga Man","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101618629","display_name":"Li Du","orcid":"https://orcid.org/0000-0001-5807-3585","observed_orcids":["https://orcid.org/0000-0001-5807-3585"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Du","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100406431","display_name":"Fengyang Wang","orcid":"https://orcid.org/0000-0002-2043-2703","observed_orcids":["https://orcid.org/0000-0002-2043-2703"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fengyang Wang","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036995681","display_name":"Qiaoling Chen","orcid":"https://orcid.org/0000-0003-4442-9450","observed_orcids":["https://orcid.org/0000-0003-4442-9450"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qiaoling Chen","raw_affiliation_strings":["Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":"https://orcid.org/0000-0003-4442-9450","affiliations":[{"raw_affiliation_string":"Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Engineering Key Lab of Haikou, College of Animal Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5036995681"],"corresponding_institution_ids":["https://openalex.org/I20942203"],"apc_list":{"value":1800,"currency":"CHF","value_usd":1885},"apc_paid":{"value":1800,"currency":"CHF","value_usd":1885},"fwci":1.7194,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.8145749,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"12","issue":"12","first_page":"1529","last_page":"1529"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10654","display_name":"Pneumonia and Respiratory Infections","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pasteurella-multocida","display_name":"Pasteurella multocida","score":0.9980000257492065},{"id":"https://openalex.org/keywords/goat-respiratory-disease","display_name":"goat respiratory disease","score":0.7429999709129333},{"id":"https://openalex.org/keywords/lung-histopathology","display_name":"lung histopathology","score":0.7300000190734863},{"id":"https://openalex.org/keywords/suppurative-pneumonia","display_name":"suppurative pneumonia","score":0.8619999885559082},{"id":"https://openalex.org/keywords/microrna-expression","display_name":"microRNA expression","score":0.8629999756813049},{"id":"https://openalex.org/keywords/mrna-expression","display_name":"mRNA expression","score":0.8149999976158142},{"id":"https://openalex.org/keywords/differentially-expressed-genes","display_name":"differentially expressed genes","score":0.9459999799728394},{"id":"https://openalex.org/keywords/host-immune-response","display_name":"host immune response","score":0.9079999923706055},{"id":"https://openalex.org/keywords/fever","display_name":"fever","score":0.4480000138282776},{"id":"https://openalex.org/keywords/immune-related-genes","display_name":"immune-related genes","score":0.656000018119812},{"id":"https://openalex.org/keywords/microrna-target-genes","display_name":"miRNA target genes","score":0.7310000061988831}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7569533586502075},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5131245255470276},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5120611786842346},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.47787919640541077},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.47787466645240784},{"id":"https://openalex.org/C152724338","wikidata":"https://www.wikidata.org/wiki/Q909442","display_name":"KEGG","level":5,"score":0.45706358551979065},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4379817247390747},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.43115657567977905},{"id":"https://openalex.org/C4692481","wikidata":"https://www.wikidata.org/wiki/Q169526","display_name":"Reverse transcription polymerase chain reaction","level":4,"score":0.41811513900756836},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3983442783355713},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.34239649772644043},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10879409313201904},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.10210254788398743}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/ani12121529","doi":"https://doi.org/10.3390/ani12121529","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ani12121529","pdf_url":"https://www.mdpi.com/2076-2615/12/12/1529/pdf?version=1655791849","source":{"id":"https://openalex.org/S4210168508","display_name":"Animals","issn_l":"2076-2615","issn":["2076-2615"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animals","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9219503","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9219503","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animals (Basel)","raw_type":"Text"},{"id":"pmid:35739866","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35739866","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animals : an open access journal from MDPI","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:559ec0e5dcd04d1fa9cda415ae50e2aa","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/559ec0e5dcd04d1fa9cda415ae50e2aa","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Animals, Vol 12, Iss 12, p 1529 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/ani12121529","doi":"https://doi.org/10.3390/ani12121529","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ani12121529","pdf_url":"https://www.mdpi.com/2076-2615/12/12/1529/pdf?version=1655791849","source":{"id":"https://openalex.org/S4210168508","display_name":"Animals","issn_l":"2076-2615","issn":["2076-2615"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animals","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6633624668","display_name":null,"funder_award_id":"No.321QN0860","funder_id":"https://openalex.org/F4320324882","funder_display_name":"Hainan Provincial Department of Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320324882","display_name":"Hainan Provincial Department of Science and Technology","ror":"https://ror.org/03rbw2w25"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4282821557.pdf","grobid_xml":"https://content.openalex.org/works/W4282821557.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W1566143144","https://openalex.org/W1584969109","https://openalex.org/W1965737875","https://openalex.org/W1980536881","https://openalex.org/W1983015423","https://openalex.org/W1983085370","https://openalex.org/W2000513178","https://openalex.org/W2006291194","https://openalex.org/W2031084334","https://openalex.org/W2035809865","https://openalex.org/W2071999825","https://openalex.org/W2101128900","https://openalex.org/W2101142880","https://openalex.org/W2114117103","https://openalex.org/W2134526812","https://openalex.org/W2150709405","https://openalex.org/W2151539516","https://openalex.org/W2152239989","https://openalex.org/W2159675211","https://openalex.org/W2171783221","https://openalex.org/W2338157594","https://openalex.org/W2695800590","https://openalex.org/W2734814984","https://openalex.org/W2735092275","https://openalex.org/W2810270463","https://openalex.org/W2884865824","https://openalex.org/W2908539086","https://openalex.org/W2922310175","https://openalex.org/W2942330674","https://openalex.org/W2946363975","https://openalex.org/W2952830394","https://openalex.org/W2971651245","https://openalex.org/W2980900371","https://openalex.org/W2999356225","https://openalex.org/W3006885479","https://openalex.org/W3012227475","https://openalex.org/W3036776293","https://openalex.org/W3048634970","https://openalex.org/W3082240868","https://openalex.org/W3085640312","https://openalex.org/W3088890340","https://openalex.org/W3173732246","https://openalex.org/W3194086032","https://openalex.org/W6783974604"],"related_works":["https://openalex.org/W4401809543","https://openalex.org/W4221081294","https://openalex.org/W2695800590","https://openalex.org/W3173732246","https://openalex.org/W7202368339","https://openalex.org/W3214440125","https://openalex.org/W2735371937","https://openalex.org/W7160593219","https://openalex.org/W4322587608","https://openalex.org/W7160655886"],"abstract_inverted_index":{"Pasteurella":[0],"multocida":[1],"(Pm)":[2],"infection":[3,17,41,85],"causes":[4],"severe":[5],"respiratory":[6],"disease":[7],"in":[8,27,120,170,223,256,283,299,319],"goats.":[9],"We":[10],"investigated":[11],"the":[12,15,20,28,50,54,64,78,83,87,91,121,148,152,232,239,244,257,268,280,284,291,300,317],"effects":[13],"of":[14,30,53,63,70,86,151,187,234,238],"Pm":[16,40,84,308,322],"intratracheally":[18],"on":[19],"histopathology,":[21],"miRNA":[22],"and":[23,37,77,99,104,108,125,131,154,178,183,189,192,209,225,249,261,272,279,304],"mRNA":[24],"expression":[25,149],"dynamics":[26],"lung":[29,66,79,227,301],"goats":[31,55,320],"infected":[32,65],"for":[33,137,315],"1,":[34,116],"2,":[35],"5":[36,270],"7":[38],"days.":[39],"caused":[42],"fever,":[43],"which":[44,310],"significantly":[45,110],"(p":[46],"<":[47,118],"0.05)":[48,119],"increased":[49],"body":[51],"temperature":[52],"from":[56,302],"day":[57],"1":[58],"to":[59,220],"5.":[60],"Haemotoxylin\u2212eosin":[61],"staining":[62],"tissue":[67],"showed":[68,231],"characteristics":[69],"suppurative":[71],"pneumonia":[72],"with":[73,90,158,243],"inflammatory":[74],"cells":[75],"infiltration":[76],"structure":[80],"destruction.":[81],"During":[82],"goats,":[88],"compared":[89],"control":[92],"group,":[93,246],"there":[94],"were":[95,135,156,168,218,253,277],"3080,":[96],"3508,":[97],"2716":[98],"2675":[100],"differentially":[101,165,215,254,274],"expressed":[102,111,166,216,255,275],"genes":[103,134,155,167,217,222,237,252,276],"42,":[105],"69,":[106],"91":[107],"108":[109],"miRNAs":[112,130,153,248,271,281],"(|log2Fold":[113],"Change|":[114],">":[115],"p":[117],"Pm_d1,":[122,258],"Pm_d2,":[123,259],"Pm_d5":[124,260],"Pm_d7":[126,262],"groups,":[127],"respectively.":[128],"Five":[129],"nine":[132],"immune-related":[133],"selected":[136],"confirmation":[138],"by":[139,161],"reverse":[140],"transcription\u2212polymerase":[141],"chain":[142],"reaction.":[143],"The":[144,164,214,229,264],"results":[145,230],"indicated":[146],"that":[147],"patterns":[150],"consistent":[157],"those":[159],"determined":[160],"next-generation":[162],"sequencing.":[163],"enriched":[169],"cytokine\u2212cytokine":[171],"receptor":[172],"interaction,":[173],"cell":[174,200],"adhesion":[175],"molecules,":[176],"complement":[177],"coagulation":[179],"cascades,":[180],"tight":[181],"junction":[182],"phagosome":[184],"Kyoto":[185],"Encyclopedia":[186],"Genes":[188],"Genomes":[190],"pathways":[191],"cytokine":[193],"production,":[194],"leukocyte":[195,198],"migration,":[196,199],"myeloid":[197],"periphery,":[201],"plasma":[202],"membrane,":[203],"extracellular":[204,207],"region":[205,208],"part,":[206],"other":[210],"Gene":[211],"Ontology":[212],"terms.":[213],"mapped":[219],"marker":[221,236],"human":[224],"mouse":[226],"cells.":[228,241],"presence":[233],"some":[235],"immune":[240,286],"Compared":[242],"CK":[245],"five":[247],"892":[250,273],"common":[251,269],"groups.":[263],"target":[265,292],"relationships":[266],"between":[267],"explored":[278],"involved":[282],"host":[285],"reaction":[287,298],"may":[288],"act":[289],"through":[290],"genes.":[293],"Our":[294],"study":[295],"characterized":[296],"goats\u2019":[297],"histopathological":[303],"molecular":[305],"changes":[306],"upon":[307],"infection,":[309],"will":[311],"provide":[312],"valuable":[313],"information":[314],"understanding":[316],"responses":[318],"during":[321],"infection.":[323]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2022-06-15T00:00:00"}