{"id":"https://openalex.org/W4281995625","doi":"https://doi.org/10.3389/fresc.2022.896114","title":"Myosteatosis as a Shared Biomarker for Sarcopenia and Cachexia Using MRI and Ultrasound","display_name":"Myosteatosis as a Shared Biomarker for Sarcopenia and Cachexia Using MRI and Ultrasound","publication_year":2022,"publication_date":"2022-05-30","ids":{"openalex":"https://openalex.org/W4281995625","doi":"https://doi.org/10.3389/fresc.2022.896114","pmid":"https://pubmed.ncbi.nlm.nih.gov/36189019","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9397668"},"language":"en","primary_location":{"id":"doi:10.3389/fresc.2022.896114","doi":"https://doi.org/10.3389/fresc.2022.896114","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fresc.2022.896114","pdf_url":"https://www.frontiersin.org/articles/10.3389/fresc.2022.896114/pdf","source":{"id":"https://openalex.org/S4210195722","display_name":"Frontiers in Rehabilitation Sciences","issn_l":"2673-6861","issn":["2673-6861"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Rehabilitation Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fresc.2022.896114/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048595642","display_name":"Jevin Jay Lortie","orcid":"https://orcid.org/0000-0001-9647-2579","observed_orcids":["https://orcid.org/0000-0001-9647-2579"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jevin Lortie","raw_affiliation_strings":["Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000680771","display_name":"Benjamin Rush","orcid":"https://orcid.org/0000-0002-9530-1927","observed_orcids":["https://orcid.org/0000-0002-9530-1927"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin Rush","raw_affiliation_strings":["Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003530030","display_name":"Katie J. Osterbauer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katie Osterbauer","raw_affiliation_strings":["Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008312324","display_name":"Timothy J. Colgan","orcid":"https://orcid.org/0000-0002-4400-7525","observed_orcids":["https://orcid.org/0000-0002-4400-7525"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T. J. Colgan","raw_affiliation_strings":["Department of Radiology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058894716","display_name":"Daiki Tamada","orcid":"https://orcid.org/0000-0003-3615-459X","observed_orcids":["https://orcid.org/0000-0003-3615-459X"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daiki Tamada","raw_affiliation_strings":["Department of Radiology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068900681","display_name":"Sujay Garlapati","orcid":"https://orcid.org/0009-0002-3236-5103","observed_orcids":["https://orcid.org/0009-0002-3236-5103"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sujay Garlapati","raw_affiliation_strings":["Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061952019","display_name":"Toby Christopher Campbell","orcid":"https://orcid.org/0000-0003-4910-1112","observed_orcids":["https://orcid.org/0000-0003-4910-1112"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Toby C. Campbell","raw_affiliation_strings":["Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002970130","display_name":"Anne M. Traynor","orcid":"https://orcid.org/0000-0001-5790-3815","observed_orcids":["https://orcid.org/0000-0001-5790-3815"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anne Traynor","raw_affiliation_strings":["Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011486016","display_name":"Ticiana A.B. Leal","orcid":"https://orcid.org/0000-0002-3735-9063","observed_orcids":["https://orcid.org/0000-0002-3735-9063"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]},{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ticiana Leal","raw_affiliation_strings":["Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, United States","Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, United States","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063448779","display_name":"Viharkumar Patel","orcid":"https://orcid.org/0000-0002-8541-6982","observed_orcids":["https://orcid.org/0000-0002-8541-6982"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Viharkumar Patel","raw_affiliation_strings":["Department of Pathology, Harvard Medical School, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Harvard Medical School, Boston, MA, United States","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033480184","display_name":"Jeffrey J. Helgager","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey J. Helgager","raw_affiliation_strings":["Department of Pathology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kenneth Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth Lee","raw_affiliation_strings":["Department of Radiology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057895132","display_name":"Scott Brian Reeder","orcid":"https://orcid.org/0000-0003-4728-8171","observed_orcids":["https://orcid.org/0000-0003-4728-8171"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott B. Reeder","raw_affiliation_strings":["Department of Radiology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068583223","display_name":"Adam J. Kuchnia","orcid":"https://orcid.org/0000-0002-3418-0965","observed_orcids":["https://orcid.org/0000-0002-3418-0965"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam J. Kuchnia","raw_affiliation_strings":["Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States","institution_ids":["https://openalex.org/I135310074"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5048595642"],"corresponding_institution_ids":["https://openalex.org/I135310074"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":1.9618,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.85830794,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"3","issue":null,"first_page":"896114","last_page":"896114"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.004999999888241291,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12279","display_name":"Body Composition Measurement Techniques","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myosteatosis","display_name":"myosteatosis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/sarcopenia","display_name":"sarcopenia","score":0.9919999837875366},{"id":"https://openalex.org/keywords/cachexia","display_name":"cachexia","score":0.9929999709129333},{"id":"https://openalex.org/keywords/proton-density-fat-fraction","display_name":"proton density fat fraction","score":0.7870000004768372},{"id":"https://openalex.org/keywords/shear-wave-elastography","display_name":"shear wave elastography","score":0.7940000295639038},{"id":"https://openalex.org/keywords/echo-intensity","display_name":"echo intensity","score":0.8859999775886536},{"id":"https://openalex.org/keywords/muscle-ultrasound","display_name":"muscle ultrasound","score":0.4819999933242798},{"id":"https://openalex.org/keywords/muscle-mri","display_name":"muscle MRI","score":0.597000002861023},{"id":"https://openalex.org/keywords/non-small-cell-lung-cancer","display_name":"non-small cell lung cancer","score":0.8519999980926514},{"id":"https://openalex.org/keywords/muscle-density","display_name":"muscle density","score":0.4350000023841858},{"id":"https://openalex.org/keywords/rectus-femoris","display_name":"rectus femoris","score":0.7480000257492065},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.40299999713897705},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.6200000047683716},{"id":"https://openalex.org/keywords/muscle-cross-sectional-area","display_name":"muscle cross-sectional area","score":0.4790000021457672},{"id":"https://openalex.org/keywords/muscle-degradation","display_name":"muscle degradation","score":0.39500001072883606},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.6700000166893005},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.4690000116825104},{"id":"https://openalex.org/keywords/systemic-anticancer-therapy","display_name":"systemic cancer therapy","score":0.5080000162124634},{"id":"https://openalex.org/keywords/histology","display_name":"histology","score":0.34200000762939453}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8995123505592346},{"id":"https://openalex.org/C2776214593","wikidata":"https://www.wikidata.org/wiki/Q1787939","display_name":"Sarcopenia","level":2,"score":0.8492971658706665},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.5589510202407837},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.5430530905723572},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.49322932958602905},{"id":"https://openalex.org/C2777704314","wikidata":"https://www.wikidata.org/wiki/Q6003455","display_name":"Cachexia","level":3,"score":0.46760430932044983},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.46669676899909973},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4644831120967865},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.27064475417137146},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.24687525629997253},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fresc.2022.896114","doi":"https://doi.org/10.3389/fresc.2022.896114","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fresc.2022.896114","pdf_url":"https://www.frontiersin.org/articles/10.3389/fresc.2022.896114/pdf","source":{"id":"https://openalex.org/S4210195722","display_name":"Frontiers in Rehabilitation Sciences","issn_l":"2673-6861","issn":["2673-6861"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Rehabilitation Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9397668","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9397668","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Rehabil Sci","raw_type":"Text"},{"id":"pmid:36189019","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36189019","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in rehabilitation sciences","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:b2b77eccd7b44a2d85f41eee84cab729","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/b2b77eccd7b44a2d85f41eee84cab729","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Rehabilitation Sciences, Vol 3 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fresc.2022.896114","doi":"https://doi.org/10.3389/fresc.2022.896114","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fresc.2022.896114","pdf_url":"https://www.frontiersin.org/articles/10.3389/fresc.2022.896114/pdf","source":{"id":"https://openalex.org/S4210195722","display_name":"Frontiers in Rehabilitation Sciences","issn_l":"2673-6861","issn":["2673-6861"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Rehabilitation Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1712026730","display_name":null,"funder_award_id":"CA014520","funder_id":"https://openalex.org/F4320310176","funder_display_name":"University of Wisconsin Carbone Cancer Center"},{"id":"https://openalex.org/G1753791066","display_name":null,"funder_award_id":"9U54 TR000021","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G1849571581","display_name":null,"funder_award_id":"DK088925","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G2582126307","display_name":"Technical Validation of MR Biomarkers of Obesity-Associated NAFLD","funder_award_id":"R01DK088925","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2661639429","display_name":null,"funder_award_id":"UL1 TR002373","funder_id":"https://openalex.org/F4320310176","funder_display_name":"University of Wisconsin Carbone Cancer Center"},{"id":"https://openalex.org/G3796872690","display_name":null,"funder_award_id":"9U54TR000021","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G4004214011","display_name":null,"funder_award_id":"P30 CA 014520","funder_id":"https://openalex.org/F4320310176","funder_display_name":"University of Wisconsin Carbone Cancer Center"},{"id":"https://openalex.org/G4276564356","display_name":"Institutional Clinical and Translational Science Award (UW-Madison)(UL1)","funder_award_id":"UL1RR025011","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G489951341","display_name":null,"funder_award_id":"#1204-001","funder_id":"https://openalex.org/F4320332976","funder_display_name":"Department of Radiology, University of Wisconsin-Madison"},{"id":"https://openalex.org/G5406386923","display_name":null,"funder_award_id":"1UL1RR025011","funder_id":"https://openalex.org/F4320316438","funder_display_name":"Georgia Clinical and Translational Science Alliance"},{"id":"https://openalex.org/G5513071522","display_name":"Confounder-Corrected Quantitative MRI Biomarkers of Hepatic","funder_award_id":"R01DK100651","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6456073272","display_name":null,"funder_award_id":"1023263","funder_id":"https://openalex.org/F4320306114","funder_display_name":"U.S. Department of Agriculture"},{"id":"https://openalex.org/G6664670630","display_name":null,"funder_award_id":"P30 CA014520","funder_id":"https://openalex.org/F4320316438","funder_display_name":"Georgia Clinical and Translational Science Alliance"},{"id":"https://openalex.org/G7368129632","display_name":"Evolution of Quantitative MRI Biomarkers of Metabolic Syndrome During Puberty","funder_award_id":"K24DK102595","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G7473568262","display_name":null,"funder_award_id":"UL1TR002373","funder_id":"https://openalex.org/F4320316438","funder_display_name":"Georgia Clinical and Translational Science Alliance"},{"id":"https://openalex.org/G8240269652","display_name":null,"funder_award_id":"DK088925","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000861884","display_name":"University of Wisconsin Institute for Clinical and Translational Research","funder_award_id":"UL1TR002373","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000870050","display_name":"UW Comprehensive Cancer Center Support","funder_award_id":"P30CA014520","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000876911","display_name":"Metabolism and Nutrition Training Program","funder_award_id":"T32DK007665","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000879256","display_name":"Institutional Career Development Core","funder_award_id":"KL2TR002374","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G916914294","display_name":null,"funder_award_id":"RSCH1317","funder_id":"https://openalex.org/F4320308932","funder_display_name":"Radiological Society of North America"}],"funders":[{"id":"https://openalex.org/F4320306114","display_name":"U.S. Department of Agriculture","ror":"https://ror.org/01na82s61"},{"id":"https://openalex.org/F4320308932","display_name":"Radiological Society of North America","ror":"https://ror.org/00rj4x019"},{"id":"https://openalex.org/F4320310176","display_name":"University of Wisconsin Carbone Cancer Center","ror":"https://ror.org/02mqqhj42"},{"id":"https://openalex.org/F4320316438","display_name":"Georgia Clinical and Translational Science Alliance","ror":"https://ror.org/034hw7m59"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332299","display_name":"National Institute of Food and Agriculture","ror":"https://ror.org/05qx3fv49"},{"id":"https://openalex.org/F4320332976","display_name":"Department of Radiology, University of Wisconsin-Madison","ror":"https://ror.org/01y2jtd41"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4281995625.pdf","grobid_xml":"https://content.openalex.org/works/W4281995625.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1632431440","https://openalex.org/W1924084714","https://openalex.org/W1977954856","https://openalex.org/W1983064902","https://openalex.org/W2003064100","https://openalex.org/W2042640403","https://openalex.org/W2076355272","https://openalex.org/W2081411169","https://openalex.org/W2083797416","https://openalex.org/W2086677650","https://openalex.org/W2088764776","https://openalex.org/W2090781545","https://openalex.org/W2090878522","https://openalex.org/W2102902846","https://openalex.org/W2110957605","https://openalex.org/W2116294028","https://openalex.org/W2118558111","https://openalex.org/W2127400865","https://openalex.org/W2130398738","https://openalex.org/W2147848346","https://openalex.org/W2154318378","https://openalex.org/W2173990401","https://openalex.org/W2238359618","https://openalex.org/W2327037637","https://openalex.org/W2341485436","https://openalex.org/W2514041450","https://openalex.org/W2556942267","https://openalex.org/W2584096274","https://openalex.org/W2736581271","https://openalex.org/W2752295539","https://openalex.org/W2784374589","https://openalex.org/W2794206529","https://openalex.org/W2886368623","https://openalex.org/W2896705252","https://openalex.org/W2897513125","https://openalex.org/W2914674294","https://openalex.org/W2950102985","https://openalex.org/W2951575149","https://openalex.org/W2981414419","https://openalex.org/W2990465848","https://openalex.org/W3021218285","https://openalex.org/W3041709199","https://openalex.org/W3043029167","https://openalex.org/W3043286619","https://openalex.org/W3047809855","https://openalex.org/W3048054064","https://openalex.org/W3080711034","https://openalex.org/W3123002231","https://openalex.org/W3129459793","https://openalex.org/W4200208103","https://openalex.org/W4248952339"],"related_works":["https://openalex.org/W4225400724","https://openalex.org/W3018937981","https://openalex.org/W4396698127","https://openalex.org/W4380758173","https://openalex.org/W4403285078","https://openalex.org/W3197881145","https://openalex.org/W7112631582","https://openalex.org/W7114004771","https://openalex.org/W3212496662","https://openalex.org/W7115898088"],"abstract_inverted_index":{"Purpose":[0],"Establish":[1],"bedside":[2,336],"biomarkers":[3,13,367],"of":[4,144,274,352,361,368],"myosteatosis":[5,39,290,304,333,362],"for":[6,30,104,118],"sarcopenia":[7,369],"and":[8,19,26,37,46,83,96,112,133,135,153,172,227,294,337,358,365,370],"cachexia.":[9,371],"We":[10,34,67,89,127],"compared":[11,35,136],"ultrasound":[12,36,327],"against":[14],"MRI-based":[15,84],"percent":[16],"fat,":[17],"histology,":[18],"CT-based":[20],"muscle":[21,131,259],"density":[22,86,260],"among":[23,41],"healthy":[24,147,151,170,194],"adults":[25,27,48,107,120,156,166,171,174,187,199,293],"undergoing":[28,54,121,157,175,200],"treatment":[29,122,158,176,201],"lung":[31,52],"cancer.":[32],"Methods":[33],"MRI":[38],"measures":[40,328],"young":[42,146,165,292],"healthy,":[43,45],"older":[44,47,106,119,150,155,169,173,193,198,282,296],"with":[49,219,231,255,264,312],"non-small":[50],"cell":[51],"cancer":[53],"systemic":[55],"treatment,":[56],"all":[57,105],"without":[58],"significant":[59],"medical":[60],"concerns,":[61],"in":[62,164,168,320],"a":[63],"cross-sectional":[64,97,246,251],"pilot":[65],"study.":[66],"assessed":[68,91],"each":[69],"participant's":[70],"rectus":[71,93,249],"femoris":[72,94,100,250],"ultrasound-based":[73],"echo":[74],"intensity":[75],"(EI),":[76],"shear":[77,80,232,355],"wave":[78,81,233,356],"elastography-based":[79],"speed,":[82,357],"proton":[85],"fat-fraction":[87],"(PDFF).":[88],"also":[90],"BMI,":[92,134,243,315],"thickness":[95],"area.":[98,252],"Rectus":[99],"biopsies":[101],"were":[102,159],"taken":[103],"(":[108,123],"n":[109,124],"=":[110,125,184,208,222,236,267,270],"20)":[111],"we":[113],"analyzed":[114],"chest":[115],"CT":[116,256],"scans":[117],"10).":[126],"determined":[128],"associations":[129,212],"between":[130,139,213,281,291,305],"assessments":[132,138,345],"these":[137],"groups.":[140,284,298],"Results":[141],"A":[142],"total":[143],"10":[145,149,154],"adults,":[148,152,195],"recruited.":[160],"PDFF":[161,215,265,286,313,359],"was":[162,216,261,287,300,309],"lower":[163,190],"than":[167,192,342],"(0.3":[177],"vs.":[178,180,203,205],"2.8":[179],"2.9%,":[181],"respectively,":[182],"p":[183,207,224,238,269],"0.01).":[185],"Young":[186],"had":[188],"significantly":[189,262],"EI":[191,220,299,308],"but":[196,241],"not":[197,242,279],"(48.6":[202],"81.8":[204],"75.4,":[206],"0.02).":[209],"When":[210],"comparing":[211],"measures,":[214],"strongly":[217,310],"associated":[218,230,263,311],"(\u03c1":[221,235,266],"0.75,":[223],"<":[225,239],"0.01)":[226,240],"moderately":[228],"negatively":[229],"speed":[234],"\u22120.49,":[237],"whole":[244],"leg":[245],"area,":[247],"or":[248,276],"Among":[253],"participants":[254],"scans,":[257],"paraspinal":[258],"\u22120.70,":[268],"0.023).":[271],"Histological":[272],"markers":[273],"inflammation":[275],"degradation":[277],"did":[278],"differ":[280],"adult":[283,297],"Conclusion":[285],"sensitive":[288,302],"to":[289,303,331],"both":[295],"less":[301],"groups,":[306],"yet":[307],"unlike":[314],"which":[316],"is":[317],"typically":[318],"used":[319],"cachexia":[321],"diagnosis.":[322],"Our":[323],"results":[324,349],"suggest":[325],"that":[326],"may":[329],"serve":[330],"determine":[332],"at":[334],"the":[335],"are":[338],"more":[339],"useful":[340],"diagnostically":[341],"traditional":[343],"weight":[344],"like":[346],"BMI.":[347],"These":[348],"show":[350],"promise":[351],"using":[353],"EI,":[354],"proxies":[360],"as":[363],"diagnostic":[364],"therapeutic":[366]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-06-13T00:00:00"}
