{"id":"https://openalex.org/W4281963797","doi":"https://doi.org/10.1016/j.isci.2022.104516","title":"pSNAP: Proteome-wide analysis of elongating nascent polypeptide chains","display_name":"pSNAP: Proteome-wide analysis of elongating nascent polypeptide chains","publication_year":2022,"publication_date":"2022-06-02","ids":{"openalex":"https://openalex.org/W4281963797","doi":"https://doi.org/10.1016/j.isci.2022.104516","pmid":"https://pubmed.ncbi.nlm.nih.gov/35754732","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9218386"},"language":"en","primary_location":{"id":"doi:10.1016/j.isci.2022.104516","doi":"https://doi.org/10.1016/j.isci.2022.104516","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.isci.2022.104516","pdf_url":"http://www.cell.com/article/S2589004222007878/pdf","source":{"id":"https://openalex.org/S2898358376","display_name":"iScience","issn_l":"2589-0042","issn":["2589-0042"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"iScience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.cell.com/article/S2589004222007878/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073906198","display_name":"Junki Uchiyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Junki Uchiyama","raw_affiliation_strings":["Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002588040","display_name":"Rohini Roy","orcid":"https://orcid.org/0000-0002-4487-4354","observed_orcids":["https://orcid.org/0000-0002-4487-4354"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I4210116810","display_name":"RIKEN Center for Biosystems Dynamics Research","ror":"https://ror.org/023rffy11","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652","https://openalex.org/I4210116810"]},{"id":"https://openalex.org/I4405286617","display_name":"Institute for Integrated Cell-Material Sciences, Kyoto University","ror":"https://ror.org/02n7ghp88","country_code":"JP","type":"facility","lineage":["https://openalex.org/I22299242","https://openalex.org/I4405286617"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Rohini Roy","raw_affiliation_strings":["Center for Biosystems Dynamics Research, RIKEN, Kobe, Hyogo 650-0047, Japan","Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan","Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto, 606-8501, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biosystems Dynamics Research, RIKEN, Kobe, Hyogo 650-0047, Japan","institution_ids":["https://openalex.org/I4210116810"]},{"raw_affiliation_string":"Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto, 606-8501, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I4405286617"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060177791","display_name":"Dan Ohtan Wang","orcid":"https://orcid.org/0000-0002-3126-8558","observed_orcids":["https://orcid.org/0000-0002-3126-8558"]},"institutions":[{"id":"https://openalex.org/I103890011","display_name":"Shenyang Pharmaceutical University","ror":"https://ror.org/03dnytd23","country_code":"CN","type":"education","lineage":["https://openalex.org/I103890011"]},{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I4210116810","display_name":"RIKEN Center for Biosystems Dynamics Research","ror":"https://ror.org/023rffy11","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652","https://openalex.org/I4210116810"]},{"id":"https://openalex.org/I4405286617","display_name":"Institute for Integrated Cell-Material Sciences, Kyoto University","ror":"https://ror.org/02n7ghp88","country_code":"JP","type":"facility","lineage":["https://openalex.org/I22299242","https://openalex.org/I4405286617"]}],"countries":["CN","JP"],"is_corresponding":false,"raw_author_name":"Dan Ohtan Wang","raw_affiliation_strings":["Center for Biosystems Dynamics Research, RIKEN, Kobe, Hyogo 650-0047, Japan","Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan","Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto, 606-8501, Japan","Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biosystems Dynamics Research, RIKEN, Kobe, Hyogo 650-0047, Japan","institution_ids":["https://openalex.org/I4210116810"]},{"raw_affiliation_string":"Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto, 606-8501, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I4405286617"]},{"raw_affiliation_string":"Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110001, China","institution_ids":["https://openalex.org/I103890011"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003597653","display_name":"Kazuya Morikawa","orcid":"https://orcid.org/0000-0003-1540-0392","observed_orcids":["https://orcid.org/0000-0003-1540-0392"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuya Morikawa","raw_affiliation_strings":["Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032111278","display_name":"Yuka Kawahara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405264757","display_name":"Center for iPS Cell Research and Application, Kyoto University","ror":"https://ror.org/02wja3x38","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242","https://openalex.org/I4405264757"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuka Kawahara","raw_affiliation_strings":["Department of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I4405264757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069086844","display_name":"Mio Iwasaki","orcid":"https://orcid.org/0000-0003-2085-732X","observed_orcids":["https://orcid.org/0000-0003-2085-732X"]},"institutions":[{"id":"https://openalex.org/I4405264757","display_name":"Center for iPS Cell Research and Application, Kyoto University","ror":"https://ror.org/02wja3x38","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242","https://openalex.org/I4405264757"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mio Iwasaki","raw_affiliation_strings":["Department of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I4405264757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014753543","display_name":"Chiaki Yoshino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Chiaki Yoshino","raw_affiliation_strings":["Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052409368","display_name":"Yuichiro Mishima","orcid":"https://orcid.org/0000-0002-1075-9454","observed_orcids":["https://orcid.org/0000-0002-1075-9454"]},"institutions":[{"id":"https://openalex.org/I168356945","display_name":"Kyoto Sangyo University","ror":"https://ror.org/05t70xh16","country_code":"JP","type":"education","lineage":["https://openalex.org/I168356945"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuichiro Mishima","raw_affiliation_strings":["Faculty of Life Sciences, Kyoto Sangyo University, Kita-ku, Kyoto 603-8555, Japan"],"raw_orcid":"https://orcid.org/0000-0002-1075-9454","affiliations":[{"raw_affiliation_string":"Faculty of Life Sciences, Kyoto Sangyo University, Kita-ku, Kyoto 603-8555, Japan","institution_ids":["https://openalex.org/I168356945"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001763350","display_name":"Yasushi Ishihama","orcid":"https://orcid.org/0000-0001-7714-203X","observed_orcids":["https://orcid.org/0000-0001-7714-203X"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I4210086383","display_name":"National Institute of Biomedical Innovation, Health and Nutrition","ror":"https://ror.org/001rkbe13","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210086383"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Yasushi Ishihama","raw_affiliation_strings":["Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan","Laboratory of Clinical and Analytical Chemistry, National Institute of Biomedical Innovation, Health and Nutrition, Ibaraki, Osaka 567-0085, Japan"],"raw_orcid":"https://orcid.org/0000-0001-7714-203X","affiliations":[{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Laboratory of Clinical and Analytical Chemistry, National Institute of Biomedical Innovation, Health and Nutrition, Ibaraki, Osaka 567-0085, Japan","institution_ids":["https://openalex.org/I4210086383"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042532056","display_name":"Koshi Imami","orcid":"https://orcid.org/0000-0002-7451-4982","observed_orcids":["https://orcid.org/0000-0002-7451-4982"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I4210086780","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19","country_code":"JP","type":"government","lineage":["https://openalex.org/I1319490839","https://openalex.org/I4210086780"]},{"id":"https://openalex.org/I4210150921","display_name":"RIKEN Center for Integrative Medical Sciences","ror":"https://ror.org/04mb6s476","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652","https://openalex.org/I4210150921"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Koshi Imami","raw_affiliation_strings":["Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan","PRESTO, Japan Science and Technology Agency (JST), Chiyoda-ku, Tokyo 102-0075, Japan","RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan"],"raw_orcid":"https://orcid.org/0000-0002-7451-4982","affiliations":[{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"PRESTO, Japan Science and Technology Agency (JST), Chiyoda-ku, Tokyo 102-0075, Japan","institution_ids":["https://openalex.org/I4210086780"]},{"raw_affiliation_string":"RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan","institution_ids":["https://openalex.org/I4210150921"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5001763350","https://openalex.org/A5042532056"],"corresponding_institution_ids":["https://openalex.org/I22299242","https://openalex.org/I4210086383","https://openalex.org/I4210086780","https://openalex.org/I4210150921"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":0.7353,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.6319145,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"25","issue":"7","first_page":"104516","last_page":"104516"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.04320000112056732,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nascent-polypeptide-chains","display_name":"nascent polypeptide chains","score":0.9129999876022339},{"id":"https://openalex.org/keywords/co-translational-modification","display_name":"co-translational modification","score":0.6980000138282776},{"id":"https://openalex.org/keywords/stable-isotope-labeling","display_name":"stable isotope labeling","score":0.8859999775886536},{"id":"https://openalex.org/keywords/silmitasertib","display_name":"silmitasertib","score":0.8190000057220459},{"id":"https://openalex.org/keywords/casein-kinase-2","display_name":"casein kinase 2","score":0.9129999876022339},{"id":"https://openalex.org/keywords/mtor-signaling","display_name":"mTOR signaling","score":0.8899999856948853},{"id":"https://openalex.org/keywords/protein-synthesis-inhibition","display_name":"protein synthesis inhibition","score":0.9810000061988831},{"id":"https://openalex.org/keywords/acetylation","display_name":"acetylation","score":0.8119999766349792},{"id":"https://openalex.org/keywords/phosphorylation","display_name":"phosphorylation","score":0.9819999933242798},{"id":"https://openalex.org/keywords/ribosome-associated-factors","display_name":"ribosome-associated factors","score":0.9160000085830688}],"concepts":[{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.753463089466095},{"id":"https://openalex.org/C88478588","wikidata":"https://www.wikidata.org/wiki/Q42244","display_name":"Ribosome","level":4,"score":0.6080064177513123},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.5990288853645325},{"id":"https://openalex.org/C182325514","wikidata":"https://www.wikidata.org/wiki/Q7322425","display_name":"Ribosome profiling","level":5,"score":0.5628465414047241},{"id":"https://openalex.org/C119157956","wikidata":"https://www.wikidata.org/wiki/Q796604","display_name":"Acetylation","level":3,"score":0.5427207946777344},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5347456336021423},{"id":"https://openalex.org/C34905852","wikidata":"https://www.wikidata.org/wiki/Q3943646","display_name":"Stable isotope labeling by amino acids in cell culture","level":4,"score":0.5163165926933289},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.5060824751853943},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.4984910488128662},{"id":"https://openalex.org/C2779200571","wikidata":"https://www.wikidata.org/wiki/Q424696","display_name":"Puromycin","level":3,"score":0.49184083938598633},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4417271018028259},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4300515055656433},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.39996200799942017},{"id":"https://openalex.org/C3675279","wikidata":"https://www.wikidata.org/wiki/Q211935","display_name":"Protein biosynthesis","level":2,"score":0.39739087224006653},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36657780408859253},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.3622305989265442},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.2510477900505066},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.10007268190383911},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08611539006233215}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1016/j.isci.2022.104516","doi":"https://doi.org/10.1016/j.isci.2022.104516","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.isci.2022.104516","pdf_url":"http://www.cell.com/article/S2589004222007878/pdf","source":{"id":"https://openalex.org/S2898358376","display_name":"iScience","issn_l":"2589-0042","issn":["2589-0042"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"iScience","raw_type":"journal-article"},{"id":"doi:10.1101/2021.09.22.461445","doi":"https://doi.org/10.1101/2021.09.22.461445","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2021.09.22.461445","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2022/04/12/2021.09.22.461445.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:9218386","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9218386","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"iScience","raw_type":"Text"},{"id":"pmid:35754732","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35754732","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"iScience","raw_type":"Journal Article"},{"id":"pmh:oai:irdb.nii.ac.jp:01221:0005851145","doi":null,"is_oa":true,"landing_page_url":"https://repository.kulib.kyoto-u.ac.jp/bitstreams/b2049177-a1e5-43a2-b254-29adce7cdbc8/download","pdf_url":"https://repository.kulib.kyoto-u.ac.jp/bitstreams/b2049177-a1e5-43a2-b254-29adce7cdbc8/download","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"iScience","raw_type":"journal article"},{"id":"pmh:oai:repository.kulib.kyoto-u.ac.jp:2433/283250","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2433/283250","pdf_url":null,"source":{"id":"https://openalex.org/S4306401454","display_name":"Kyoto University Research Information Repository (Kyoto University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I22299242","host_organization_name":"Kyoto University","host_organization_lineage":["https://openalex.org/I22299242"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"journal article"}],"best_oa_location":{"id":"doi:10.1016/j.isci.2022.104516","doi":"https://doi.org/10.1016/j.isci.2022.104516","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.isci.2022.104516","pdf_url":"http://www.cell.com/article/S2589004222007878/pdf","source":{"id":"https://openalex.org/S2898358376","display_name":"iScience","issn_l":"2589-0042","issn":["2589-0042"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"iScience","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1939565965","display_name":null,"funder_award_id":"20H04844","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G332886466","display_name":null,"funder_award_id":"18dm0307023h","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G3478193549","display_name":null,"funder_award_id":"JPMJPR18H2","funder_id":"https://openalex.org/F4320338111","funder_display_name":"Precursory Research for Embryonic Science and Technology"},{"id":"https://openalex.org/G4331731063","display_name":null,"funder_award_id":"17H05667","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G4624254123","display_name":"Dissecting the co-translational modifications by quantitative proteomics","funder_award_id":"20H03241","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G5440424050","display_name":null,"funder_award_id":"21H05720","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6229976359","display_name":"mRNA chemical modification in activity-dependent establishment of neural circuits","funder_award_id":"21H02580","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7171859098","display_name":"A method for identifying the mitoribosome interactome","funder_award_id":"18K14674","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8753768476","display_name":null,"funder_award_id":"JPMJER2101","funder_id":"https://openalex.org/F4320338112","funder_display_name":"Exploratory Research for Advanced Technology"}],"funders":[{"id":"https://openalex.org/F4320307783","display_name":"Dow Chemical Company","ror":"https://ror.org/032hx4q18"},{"id":"https://openalex.org/F4320309254","display_name":"Harvard Medical School","ror":null},{"id":"https://openalex.org/F4320309807","display_name":"Takeda Science Foundation","ror":"https://ror.org/02y123g31"},{"id":"https://openalex.org/F4320311405","display_name":"Japan Agency for Medical Research and Development","ror":"https://ror.org/004rtk039"},{"id":"https://openalex.org/F4320322704","display_name":"Tokyo Institute of Technology","ror":"https://ror.org/0112mx960"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"},{"id":"https://openalex.org/F4320334789","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19"},{"id":"https://openalex.org/F4320338111","display_name":"Precursory Research for Embryonic Science and Technology","ror":null},{"id":"https://openalex.org/F4320338112","display_name":"Exploratory Research for Advanced Technology","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4281963797.pdf","grobid_xml":"https://content.openalex.org/works/W4281963797.grobid-xml"},"referenced_works_count":66,"referenced_works":["https://openalex.org/W1891202747","https://openalex.org/W1980396381","https://openalex.org/W1981251596","https://openalex.org/W1992745008","https://openalex.org/W2011769238","https://openalex.org/W2019050932","https://openalex.org/W2031704362","https://openalex.org/W2036321220","https://openalex.org/W2037632846","https://openalex.org/W2042809289","https://openalex.org/W2051119464","https://openalex.org/W2053213729","https://openalex.org/W2061463538","https://openalex.org/W2064437293","https://openalex.org/W2076358214","https://openalex.org/W2079517684","https://openalex.org/W2080352379","https://openalex.org/W2080752012","https://openalex.org/W2088897156","https://openalex.org/W2088938650","https://openalex.org/W2104726963","https://openalex.org/W2105575738","https://openalex.org/W2120728136","https://openalex.org/W2122540435","https://openalex.org/W2128551987","https://openalex.org/W2136272779","https://openalex.org/W2157162286","https://openalex.org/W2163505253","https://openalex.org/W2167844024","https://openalex.org/W2292163838","https://openalex.org/W2338172248","https://openalex.org/W2338181945","https://openalex.org/W2463195069","https://openalex.org/W2476058349","https://openalex.org/W2529263647","https://openalex.org/W2557925011","https://openalex.org/W2559991600","https://openalex.org/W2587023114","https://openalex.org/W2737050410","https://openalex.org/W2782020745","https://openalex.org/W2785857534","https://openalex.org/W2789605661","https://openalex.org/W2792476997","https://openalex.org/W2811273839","https://openalex.org/W2891583395","https://openalex.org/W2896740594","https://openalex.org/W2907067538","https://openalex.org/W2919162898","https://openalex.org/W2921660925","https://openalex.org/W2928665623","https://openalex.org/W2937706407","https://openalex.org/W2953394889","https://openalex.org/W2963950918","https://openalex.org/W2967628972","https://openalex.org/W2971695115","https://openalex.org/W2993777255","https://openalex.org/W3019545037","https://openalex.org/W3035721859","https://openalex.org/W3037945517","https://openalex.org/W3086887537","https://openalex.org/W3087854134","https://openalex.org/W3098262867","https://openalex.org/W3114249272","https://openalex.org/W3119115403","https://openalex.org/W3154562423","https://openalex.org/W3195669443"],"related_works":["https://openalex.org/W3086887537","https://openalex.org/W130768354","https://openalex.org/W2329188228","https://openalex.org/W7020902325","https://openalex.org/W7133344166","https://openalex.org/W4283449891","https://openalex.org/W2252854983","https://openalex.org/W4416389599","https://openalex.org/W2617949040","https://openalex.org/W4412588540"],"abstract_inverted_index":{"Cellular":[0],"global":[1],"translation":[2],"is":[3],"often":[4],"measured":[5],"using":[6],"ribosome":[7,58],"profiling":[8,42],"or":[9],"quantitative":[10],"mass":[11],"spectrometry,":[12],"but":[13],"these":[14],"methods":[15],"do":[16],"not":[17,56],"provide":[18],"direct":[19],"information":[20],"at":[21],"the":[22,79,110,123],"level":[23],"of":[24,43,48,81,112,115,126],"elongating":[25],"nascent":[26],"polypeptide":[27],"chains":[28],"(NPCs)":[29],"and":[30,50,63,89,98,107,120],"associated":[31],"co-translational":[32,142],"events.":[33],"Here,":[34],"we":[35],"describe":[36],"pSNAP,":[37],"a":[38,83,138,145],"method":[39],"for":[40,87,140],"proteome-wide":[41,146],"NPCs":[44,67,106],"by":[45],"affinity":[46],"enrichment":[47],"puromycin-":[49],"stable":[51],"isotope-labeled":[52],"polypeptides.":[53],"pSNAP":[54,76,136],"does":[55],"require":[57],"purification":[59],"and/or":[60],"chemical":[61],"labeling,":[62],"captures":[64],"bona":[65],"fide":[66],"that":[68,109],"characteristically":[69],"exhibit":[70],"protein":[71],"N-terminus-biased":[72],"positions.":[73],"We":[74,101],"applied":[75],"to":[77],"evaluate":[78],"effect":[80],"silmitasertib,":[82],"potential":[84],"molecular":[85],"therapy":[86],"cancer,":[88],"revealed":[90],"acute":[91],"translational":[92],"repression":[93],"through":[94],"casein":[95],"kinase":[96],"II":[97],"mTOR":[99],"pathways.":[100],"also":[102],"characterized":[103],"modifications":[104],"on":[105,144],"demonstrated":[108],"combination":[111],"different":[113],"types":[114],"modifications,":[116],"such":[117],"as":[118],"acetylation":[119],"phosphorylation":[121],"in":[122],"N-terminal":[124],"region":[125],"histone":[127],"H1.5,":[128],"can":[129],"modulate":[130],"interactions":[131],"with":[132],"ribosome-associated":[133],"factors.":[134],"Thus,":[135],"provides":[137],"framework":[139],"dissecting":[141],"regulations":[143],"scale.":[147]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2022-06-13T00:00:00"}
