{"id":"https://openalex.org/W4281807441","doi":"https://doi.org/10.7759/cureus.24408","title":"Effectiveness of Calcium Sulfate and Hydroxyapatite Composite in Collapse Prevention in Osteonecrosis of Femoral Head","display_name":"Effectiveness of Calcium Sulfate and Hydroxyapatite Composite in Collapse Prevention in Osteonecrosis of Femoral Head","publication_year":2022,"publication_date":"2022-04-23","ids":{"openalex":"https://openalex.org/W4281807441","doi":"https://doi.org/10.7759/cureus.24408","pmid":"https://pubmed.ncbi.nlm.nih.gov/35619872","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9125949"},"language":"en","primary_location":{"id":"doi:10.7759/cureus.24408","doi":"https://doi.org/10.7759/cureus.24408","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.24408","pdf_url":"https://www.cureus.com/articles/93627-effectiveness-of-calcium-sulfate-and-hydroxyapatite-composite-in-collapse-prevention-in-osteonecrosis-of-femoral-head.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.cureus.com/articles/93627-effectiveness-of-calcium-sulfate-and-hydroxyapatite-composite-in-collapse-prevention-in-osteonecrosis-of-femoral-head.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022113580","display_name":"Javed Jameel","orcid":"https://orcid.org/0009-0003-7916-7363","observed_orcids":["https://orcid.org/0009-0003-7916-7363"]},"institutions":[{"id":"https://openalex.org/I19716509","display_name":"Jamia Hamdard","ror":"https://ror.org/03dwxvb85","country_code":"IN","type":"education","lineage":["https://openalex.org/I19716509"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Javed Jameel","raw_affiliation_strings":["Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND","institution_ids":["https://openalex.org/I19716509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027344819","display_name":"Siddhartha Sinha","orcid":"https://orcid.org/0000-0002-3582-5542","observed_orcids":["https://orcid.org/0000-0002-3582-5542"]},"institutions":[{"id":"https://openalex.org/I19716509","display_name":"Jamia Hamdard","ror":"https://ror.org/03dwxvb85","country_code":"IN","type":"education","lineage":["https://openalex.org/I19716509"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Siddhartha Sinha","raw_affiliation_strings":["Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND","institution_ids":["https://openalex.org/I19716509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019288107","display_name":"Arvind Kumar","orcid":"https://orcid.org/0000-0002-6224-3636","observed_orcids":["https://orcid.org/0000-0002-6224-3636"]},"institutions":[{"id":"https://openalex.org/I19716509","display_name":"Jamia Hamdard","ror":"https://ror.org/03dwxvb85","country_code":"IN","type":"education","lineage":["https://openalex.org/I19716509"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Arvind Kumar","raw_affiliation_strings":["Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND","institution_ids":["https://openalex.org/I19716509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112549570","display_name":"Owais Ahmed Qureshi","orcid":"https://orcid.org/0000-0002-5227-2169","observed_orcids":["https://orcid.org/0000-0002-5227-2169"]},"institutions":[{"id":"https://openalex.org/I19716509","display_name":"Jamia Hamdard","ror":"https://ror.org/03dwxvb85","country_code":"IN","type":"education","lineage":["https://openalex.org/I19716509"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Owais A Qureshi","raw_affiliation_strings":["Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND","institution_ids":["https://openalex.org/I19716509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081395323","display_name":"Sandeep Kumar","orcid":"https://orcid.org/0000-0003-0469-4807","observed_orcids":["https://orcid.org/0000-0003-0469-4807"]},"institutions":[{"id":"https://openalex.org/I19716509","display_name":"Jamia Hamdard","ror":"https://ror.org/03dwxvb85","country_code":"IN","type":"education","lineage":["https://openalex.org/I19716509"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sandeep Kumar","raw_affiliation_strings":["Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND","institution_ids":["https://openalex.org/I19716509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101897721","display_name":"Neel Aggarwal","orcid":"https://orcid.org/0000-0002-6618-9032","observed_orcids":["https://orcid.org/0000-0002-6618-9032"]},"institutions":[{"id":"https://openalex.org/I19716509","display_name":"Jamia Hamdard","ror":"https://ror.org/03dwxvb85","country_code":"IN","type":"education","lineage":["https://openalex.org/I19716509"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Neel Aggarwal","raw_affiliation_strings":["Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND","institution_ids":["https://openalex.org/I19716509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007255653","display_name":"Anmol Dua","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19716509","display_name":"Jamia Hamdard","ror":"https://ror.org/03dwxvb85","country_code":"IN","type":"education","lineage":["https://openalex.org/I19716509"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Anmol Dua","raw_affiliation_strings":["Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND","institution_ids":["https://openalex.org/I19716509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120438635","display_name":"Junaid Nagori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19716509","display_name":"Jamia Hamdard","ror":"https://ror.org/03dwxvb85","country_code":"IN","type":"education","lineage":["https://openalex.org/I19716509"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mohd Junaid Nagori","raw_affiliation_strings":["Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND","institution_ids":["https://openalex.org/I19716509"]}]},{"author_position":"last","author":{"id":null,"display_name":"Rizwan Khan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19716509","display_name":"Jamia Hamdard","ror":"https://ror.org/03dwxvb85","country_code":"IN","type":"education","lineage":["https://openalex.org/I19716509"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rizwan Khan","raw_affiliation_strings":["Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedics, Hamdard Institute of Medical Sciences and Research, New Delhi, IND","institution_ids":["https://openalex.org/I19716509"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5019288107"],"corresponding_institution_ids":["https://openalex.org/I19716509"],"apc_list":null,"apc_paid":null,"fwci":0.7031,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.64928443,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":97},"biblio":{"volume":"14","issue":"4","first_page":"e24408","last_page":"e24408"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12209","display_name":"Bone and Joint Diseases","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12209","display_name":"Bone and Joint Diseases","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11218","display_name":"Hip disorders and treatments","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/avascular-necrosis-of-the-femoral-head","display_name":"osteonecrosis of the femoral head","score":0.9869999885559082},{"id":"https://openalex.org/keywords/core-decompression","display_name":"core decompression","score":0.9079999923706055},{"id":"https://openalex.org/keywords/calcium-sulfate","display_name":"calcium sulfate","score":0.7590000033378601},{"id":"https://openalex.org/keywords/hydroxyapatite","display_name":"hydroxyapatite","score":0.9909999966621399},{"id":"https://openalex.org/keywords/autologous-iliac-bone-graft","display_name":"autologous iliac bone graft","score":0.8080000281333923},{"id":"https://openalex.org/keywords/femoral-head-collapse","display_name":"femoral head collapse","score":0.8299999833106995},{"id":"https://openalex.org/keywords/collapse-prevention","display_name":"collapse prevention","score":0.5979999899864197},{"id":"https://openalex.org/keywords/hip","display_name":"hip","score":0.4090000092983246}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9264335632324219},{"id":"https://openalex.org/C2776350087","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Cancellous bone","level":2,"score":0.7368534803390503},{"id":"https://openalex.org/C2779100257","wikidata":"https://www.wikidata.org/wiki/Q582849","display_name":"Femoral head","level":2,"score":0.604946494102478},{"id":"https://openalex.org/C2779480328","wikidata":"https://www.wikidata.org/wiki/Q1183684","display_name":"Decompression","level":2,"score":0.5168091058731079},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.514258086681366},{"id":"https://openalex.org/C2779079599","wikidata":"https://www.wikidata.org/wiki/Q3774464","display_name":"Iliac crest","level":2,"score":0.4745175242424011},{"id":"https://openalex.org/C190892606","wikidata":"https://www.wikidata.org/wiki/Q3512464","display_name":"Radiological weapon","level":2,"score":0.4620110094547272},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.40959274768829346}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.7759/cureus.24408","doi":"https://doi.org/10.7759/cureus.24408","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.24408","pdf_url":"https://www.cureus.com/articles/93627-effectiveness-of-calcium-sulfate-and-hydroxyapatite-composite-in-collapse-prevention-in-osteonecrosis-of-femoral-head.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9125949","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9125949","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Text"},{"id":"pmid:35619872","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35619872","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.7759/cureus.24408","doi":"https://doi.org/10.7759/cureus.24408","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.24408","pdf_url":"https://www.cureus.com/articles/93627-effectiveness-of-calcium-sulfate-and-hydroxyapatite-composite-in-collapse-prevention-in-osteonecrosis-of-femoral-head.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4281807441.pdf","grobid_xml":"https://content.openalex.org/works/W4281807441.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W1928774000","https://openalex.org/W1987650869","https://openalex.org/W1993413471","https://openalex.org/W2006863498","https://openalex.org/W2014092920","https://openalex.org/W2056287077","https://openalex.org/W2064409905","https://openalex.org/W2117945509","https://openalex.org/W2167627831","https://openalex.org/W2330314988","https://openalex.org/W2768664625","https://openalex.org/W2789766969","https://openalex.org/W2807241802","https://openalex.org/W2900329410","https://openalex.org/W3038721425","https://openalex.org/W3204346720"],"related_works":["https://openalex.org/W2167627831","https://openalex.org/W2475114479","https://openalex.org/W4386023298","https://openalex.org/W3030160685","https://openalex.org/W2035919665","https://openalex.org/W2087544954","https://openalex.org/W1993413471","https://openalex.org/W2599294837","https://openalex.org/W7133480599","https://openalex.org/W2172211119"],"abstract_inverted_index":{"Introduction":[0],"Calcium-sulfate-hydroxyapatite":[1],"bioceramics":[2,45],"have":[3],"been":[4],"widely":[5],"used":[6],"as":[7,15,46,84,184],"void":[8,16,48,85,126,177,186],"fillers":[9,17,86],"in":[10,18,28,50,104,166,188,201,211],"bone.":[11],"However,":[12],"their":[13],"effectiveness":[14,42],"core":[19,52,140,189,213],"decompression":[20,53,214],"for":[21,55,191],"osteonecrosis":[22],"of":[23,43,66,95,102,112,182,203],"the":[24,41,51,61,99,105,113,121,172,197,212],"femoral":[25,30],"head":[26,31],"(ONFH)":[27],"preventing":[29],"collapse":[32,103,116,167,204],"prevention":[33,205],"has":[34],"limited":[35],"evidence.":[36],"The":[37,92,115,150,156,180],"current":[38],"study":[39,97,130],"investigates":[40],"calcium-sulfate-hydroxyapatite":[44,81,183],"a":[47,185],"filler":[49,187],"procedure":[54],"ONFH.":[56],"Methods":[57],"We":[58],"retrospectively":[59],"reviewed":[60],"clinical":[62],"and":[63,146,206,216],"radiological":[64,100],"records":[65,133],"ONFH":[67,192],"patients":[68],"that":[69,138],"underwent":[70,139],"core-decompression":[71],"using":[72],"either":[73],"autologous":[74,198],"iliac":[75],"crest":[76],"cancellous":[77,199],"bone":[78,200],"graft":[79],"or":[80],"bioceramic":[82],"paste":[83],"with":[87,134],"at":[88],"least":[89],"one-year":[90],"follow-up.":[91],"primary":[93],"outcome":[94],"this":[96],"was":[98,118,153,160],"progression":[101,117,168],"last":[106],"available":[107],"standard":[108],"anteroposterior":[109],"(AP)":[110],"radiographs":[111],"hip.":[114],"compared":[119],"between":[120,171],"two":[122,173],"groups":[123,174],"based":[124,175],"on":[125,176],"fillers.":[127,178],"Results":[128],"This":[129],"included":[131],"patient":[132],"44":[135],"hip":[136],"joints":[137],"decompression.":[141],"There":[142],"were":[143,169],"five":[144],"female":[145],"33":[147],"male":[148],"patients.":[149],"mean":[151,157],"age":[152],"29.1\u00b16.3":[154],"years.":[155],"follow-up":[158],"duration":[159],"21.4\u00b13.4":[161],"months.":[162],"No":[163],"significant":[164],"differences":[165],"observed":[170],"Conclusion":[179],"use":[181],"decompress":[190],"is":[193],"not":[194],"superior":[195],"to":[196],"terms":[202],"mechanical":[207],"support.":[208],"Further":[209],"modifications":[210],"techniques":[215],"well-planned":[217],"prospective":[218],"studies":[219],"would":[220],"help":[221],"establish":[222],"sound":[223],"recommendations.":[224]},"counts_by_year":[{"year":2025,"cited_by_count":3}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2022-06-13T00:00:00"}