{"id":"https://openalex.org/W4281793263","doi":"https://doi.org/10.31083/j.jin2104106","title":"Craniofacial reconstructions in children with craniosynostosis","display_name":"Craniofacial reconstructions in children with craniosynostosis","publication_year":2022,"publication_date":"2022-06-01","ids":{"openalex":"https://openalex.org/W4281793263","doi":"https://doi.org/10.31083/j.jin2104106","pmid":"https://pubmed.ncbi.nlm.nih.gov/35864758"},"language":"en","primary_location":{"id":"doi:10.31083/j.jin2104106","doi":"https://doi.org/10.31083/j.jin2104106","is_oa":true,"landing_page_url":"https://doi.org/10.31083/j.jin2104106","pdf_url":"https://www.imrpress.com/journal/JIN/21/4/10.31083/j.jin2104106/pdf","source":{"id":"https://openalex.org/S137215245","display_name":"Journal of Integrative Neuroscience","issn_l":"0219-6352","issn":["0219-6352","1757-448X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","medline","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Integrative Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.imrpress.com/journal/JIN/21/4/10.31083/j.jin2104106/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069185723","display_name":"Peter Spazzapan","orcid":"https://orcid.org/0000-0002-5278-7947","observed_orcids":["https://orcid.org/0000-0002-5278-7947"]},"institutions":[{"id":"https://openalex.org/I2801323708","display_name":"Ljubljana University Medical Centre","ror":"https://ror.org/01nr6fy72","country_code":"SI","type":"healthcare","lineage":["https://openalex.org/I2801323708"]}],"countries":["SI"],"is_corresponding":true,"raw_author_name":"Peter Spazzapan","raw_affiliation_strings":["Paediatric Neurosurgery Unit, Clinical Department of Neurosurgery, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia"],"raw_orcid":"https://orcid.org/0000-0002-5278-7947","affiliations":[{"raw_affiliation_string":"Paediatric Neurosurgery Unit, Clinical Department of Neurosurgery, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia","institution_ids":["https://openalex.org/I2801323708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005836850","display_name":"Miha Ko\u010dar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801323708","display_name":"Ljubljana University Medical Centre","ror":"https://ror.org/01nr6fy72","country_code":"SI","type":"healthcare","lineage":["https://openalex.org/I2801323708"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Miha Kocar","raw_affiliation_strings":["Clinical Department of Maxillofacial and Oral Surgery, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Department of Maxillofacial and Oral Surgery, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia","institution_ids":["https://openalex.org/I2801323708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074924527","display_name":"Andreja Eberlinc","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801323708","display_name":"Ljubljana University Medical Centre","ror":"https://ror.org/01nr6fy72","country_code":"SI","type":"healthcare","lineage":["https://openalex.org/I2801323708"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Andreja Eberlinc","raw_affiliation_strings":["Clinical Department of Maxillofacial and Oral Surgery, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Department of Maxillofacial and Oral Surgery, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia","institution_ids":["https://openalex.org/I2801323708"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Barbara Haber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801323708","display_name":"Ljubljana University Medical Centre","ror":"https://ror.org/01nr6fy72","country_code":"SI","type":"healthcare","lineage":["https://openalex.org/I2801323708"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Barbara Haber","raw_affiliation_strings":["Paediatric Neurosurgery Unit, Clinical Department of Neurosurgery, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Paediatric Neurosurgery Unit, Clinical Department of Neurosurgery, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia","institution_ids":["https://openalex.org/I2801323708"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079708135","display_name":"Toma\u017e Velnar","orcid":"https://orcid.org/0000-0002-6283-4348","observed_orcids":["https://orcid.org/0000-0002-6283-4348"]},"institutions":[{"id":"https://openalex.org/I2801323708","display_name":"Ljubljana University Medical Centre","ror":"https://ror.org/01nr6fy72","country_code":"SI","type":"healthcare","lineage":["https://openalex.org/I2801323708"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Tomaz Velnar","raw_affiliation_strings":["Paediatric Neurosurgery Unit, Clinical Department of Neurosurgery, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Paediatric Neurosurgery Unit, Clinical Department of Neurosurgery, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia","institution_ids":["https://openalex.org/I2801323708"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5069185723"],"corresponding_institution_ids":["https://openalex.org/I2801323708"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":1.4906,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.81177881,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"21","issue":"4","first_page":"106","last_page":"106"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11679","display_name":"Craniofacial Disorders and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11679","display_name":"Craniofacial Disorders and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11866","display_name":"Reconstructive Facial Surgery Techniques","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12830","display_name":"Pectus Deformity Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/craniosynostosis","display_name":"craniosynostosis","score":1.0},{"id":"https://openalex.org/keywords/craniofacial-reconstruction","display_name":"craniofacial reconstruction","score":0.9399999976158142},{"id":"https://openalex.org/keywords/pediatric-neurosurgery","display_name":"pediatric neurosurgery","score":0.7889999747276306},{"id":"https://openalex.org/keywords/sagittal-craniosynostosis","display_name":"sagittal craniosynostosis","score":0.8370000123977661},{"id":"https://openalex.org/keywords/metopic-craniosynostosis","display_name":"metopic craniosynostosis","score":0.9769999980926514},{"id":"https://openalex.org/keywords/syndromic-craniosynostosis","display_name":"syndromic craniosynostosis","score":0.9409999847412109},{"id":"https://openalex.org/keywords/intracranial-hypertension","display_name":"intracranial hypertension","score":0.921999990940094},{"id":"https://openalex.org/keywords/hydrocephalus","display_name":"hydrocephalus","score":0.7879999876022339},{"id":"https://openalex.org/keywords/chiari-malformation","display_name":"Chiari malformation","score":0.9459999799728394},{"id":"https://openalex.org/keywords/cranial-sutures","display_name":"cranial sutures","score":0.5320000052452087},{"id":"https://openalex.org/keywords/surgical-complications","display_name":"surgical complications","score":0.593999981880188}],"concepts":[{"id":"https://openalex.org/C2779302956","wikidata":"https://www.wikidata.org/wiki/Q378183","display_name":"Craniosynostosis","level":2,"score":0.9322108030319214},{"id":"https://openalex.org/C2779713988","wikidata":"https://www.wikidata.org/wiki/Q1148039","display_name":"Neurocranium","level":3,"score":0.7841465473175049},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.72508704662323},{"id":"https://openalex.org/C12770488","wikidata":"https://www.wikidata.org/wiki/Q188449","display_name":"Neurosurgery","level":2,"score":0.7214295864105225},{"id":"https://openalex.org/C24543465","wikidata":"https://www.wikidata.org/wiki/Q3563467","display_name":"Cranial vault","level":3,"score":0.7035729289054871},{"id":"https://openalex.org/C2779300802","wikidata":"https://www.wikidata.org/wiki/Q13147","display_name":"Skull","level":2,"score":0.6558844447135925},{"id":"https://openalex.org/C2778607769","wikidata":"https://www.wikidata.org/wiki/Q775482","display_name":"Sagittal suture","level":3,"score":0.6037032008171082},{"id":"https://openalex.org/C2778043341","wikidata":"https://www.wikidata.org/wiki/Q5182142","display_name":"Craniofacial surgery","level":3,"score":0.5710773468017578},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5646775960922241},{"id":"https://openalex.org/C2781245598","wikidata":"https://www.wikidata.org/wiki/Q5182134","display_name":"Craniofacial","level":2,"score":0.5395803451538086},{"id":"https://openalex.org/C2778134817","wikidata":"https://www.wikidata.org/wiki/Q193003","display_name":"Hydrocephalus","level":2,"score":0.5284490585327148},{"id":"https://openalex.org/C2777327002","wikidata":"https://www.wikidata.org/wiki/Q2865760","display_name":"Fibrous joint","level":2,"score":0.5168564915657043},{"id":"https://openalex.org/C2911059045","wikidata":"https://www.wikidata.org/wiki/Q378183","display_name":"Craniosynostoses","level":3,"score":0.4660699665546417},{"id":"https://openalex.org/C2776673712","wikidata":"https://www.wikidata.org/wiki/Q2141048","display_name":"Synostosis","level":2,"score":0.44915124773979187},{"id":"https://openalex.org/C2778888786","wikidata":"https://www.wikidata.org/wiki/Q1760294","display_name":"Trigonocephaly","level":3,"score":0.4193616211414337},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003393","descriptor_name":"Cranial Sutures","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":false},{"descriptor_ui":"D003393","descriptor_name":"Cranial Sutures","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D003398","descriptor_name":"Craniosynostoses","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D003398","descriptor_name":"Craniosynostoses","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012886","descriptor_name":"Skull","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":false},{"descriptor_ui":"D012886","descriptor_name":"Skull","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D019651","descriptor_name":"Plastic Surgery Procedures","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.31083/j.jin2104106","doi":"https://doi.org/10.31083/j.jin2104106","is_oa":true,"landing_page_url":"https://doi.org/10.31083/j.jin2104106","pdf_url":"https://www.imrpress.com/journal/JIN/21/4/10.31083/j.jin2104106/pdf","source":{"id":"https://openalex.org/S137215245","display_name":"Journal of Integrative Neuroscience","issn_l":"0219-6352","issn":["0219-6352","1757-448X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","medline","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Integrative Neuroscience","raw_type":"journal-article"},{"id":"pmid:35864758","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35864758","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of integrative neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:3d7295efcec043a9bd62bc661ffb64e6","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/3d7295efcec043a9bd62bc661ffb64e6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Integrative Neuroscience, Vol 21, Iss 4, p 106 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.31083/j.jin2104106","doi":"https://doi.org/10.31083/j.jin2104106","is_oa":true,"landing_page_url":"https://doi.org/10.31083/j.jin2104106","pdf_url":"https://www.imrpress.com/journal/JIN/21/4/10.31083/j.jin2104106/pdf","source":{"id":"https://openalex.org/S137215245","display_name":"Journal of Integrative Neuroscience","issn_l":"0219-6352","issn":["0219-6352","1757-448X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","medline","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Integrative Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9789000153541565,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4281793263.pdf","grobid_xml":"https://content.openalex.org/works/W4281793263.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1683465346","https://openalex.org/W1983733684","https://openalex.org/W2040565494","https://openalex.org/W2068505389","https://openalex.org/W2075310320","https://openalex.org/W2092952170","https://openalex.org/W2115224457","https://openalex.org/W2155932531","https://openalex.org/W2180266132","https://openalex.org/W2530543843","https://openalex.org/W2531827678","https://openalex.org/W2626233920","https://openalex.org/W2909038055","https://openalex.org/W2984329026","https://openalex.org/W3003301789","https://openalex.org/W3049713119","https://openalex.org/W3093040852","https://openalex.org/W3133513395","https://openalex.org/W3146542672","https://openalex.org/W3164801973","https://openalex.org/W3165217739","https://openalex.org/W3169615171","https://openalex.org/W3175820150","https://openalex.org/W3192054668","https://openalex.org/W3201021477","https://openalex.org/W4200006479","https://openalex.org/W4235076181","https://openalex.org/W4255375011"],"related_works":["https://openalex.org/W4232871348","https://openalex.org/W2018098533","https://openalex.org/W3005237299","https://openalex.org/W7131276595","https://openalex.org/W4223516549","https://openalex.org/W3091391529","https://openalex.org/W1969464013","https://openalex.org/W1976862728","https://openalex.org/W7211994147","https://openalex.org/W2402389584"],"abstract_inverted_index":{"BACKGROUND:":[0],"Craniosynostosis":[1],"is":[2,188,211,248],"a":[3,192,228,251],"rare":[4],"congenital":[5],"disease":[6],"of":[7,33,58,61,144,160,186,208,230,236,245,254],"the":[8,34,56,62,104,145,214,220,231,237,242,255],"skull.":[9],"They":[10],"arise":[11],"when":[12],"one":[13],"or":[14],"more":[15],"cranial":[16,166],"sutures":[17,137],"ossify":[18],"prematurely.":[19],"This":[20,226],"causes":[21],"an":[22],"obstruction":[23],"to":[24,30,212,249],"normal":[25,252],"brain":[26],"growth":[27],"and":[28,42,70,99,131,190,199,204,216],"leads":[29],"specific":[31],"deformations":[32],"skull,":[35],"which":[36],"may":[37],"result":[38],"in":[39,140,197],"intracranial":[40,88],"hypertension":[41],"cognitive":[43],"delay.":[44],"MATERIALS":[45],"AND":[46],"METHODS:":[47],"We":[48],"have":[49,76,109,153],"retrospectively":[50],"analysed":[51],"all":[52],"children":[53,108],"treated":[54,111],"at":[55,91,178],"Unit":[57],"paediatric":[59],"neurosurgery":[60],"University":[63],"Medical":[64],"Centre":[65],"Ljubljana":[66],"between":[67],"June":[68],"2015":[69],"September":[71],"2020.":[72],"The":[73,114,184,206],"following":[74],"items":[75],"been":[77,110,154],"recorded:":[78],"affected":[79,139],"suture,":[80],"underlying":[81],"syndromic":[82],"condition,":[83],"hydrocephalus,":[84],"Chiari":[85],"malformation,":[86],"raised":[87],"pressure,":[89],"age":[90,177],"surgery,":[92,201],"surgical":[93,100,151,189,209,246],"technique,":[94],"need":[95],"for":[96,112],"multiple":[97],"operations":[98],"complications.":[101],"RESULTS:":[102],"During":[103],"study":[105],"period,":[106],"71":[107],"craniosynostosis.":[113,135],"median":[115],"postoperative":[116],"follow-up":[117],"was":[118,180],"31":[119],"months.":[120,182],"There":[121],"were:":[122],"54.9%":[123],"sagittal,":[124],"25.3%":[125],"metopic,":[126],"14.0%":[127],"unicoronal,":[128],"1.4%":[129,132],"bicoronal":[130],"unilateral":[133],"lambdoid":[134],"Multiple":[136],"were":[138,147],"2.8%":[141],"cases.":[142],"7.0%":[143],"cases":[146],"syndromic.":[148],"Overall,":[149],"74":[150],"procedures":[152],"performed:":[155],"frontoorbital":[156],"advancement":[157],"represented":[158],"40.5%":[159],"them;":[161],"biparietal":[162],"remodelling":[163,168,229],"32.4%:":[164],"total":[165],"vault":[167],"22.9%;":[169],"posterior":[170,173],"distraction":[171],"2.7%;":[172],"expansion":[174],"1.3%.":[175],"Median":[176],"surgery":[179,203],"12.8":[181],"CONCLUSIONS:":[183],"treatment":[185,210,247],"craniosynostosis":[187],"requires":[191,227],"multidisciplinary":[193],"approach,":[194],"with":[195],"expertise":[196],"plastic":[198],"reconstructive":[200],"maxillofacial":[202],"neurosurgery.":[205],"aim":[207,244],"release":[213],"constrictive":[215],"deformative":[217],"effect":[218],"that":[219],"synostosis":[221],"has":[222],"on":[223],"skull":[224],"growth.":[225],"neurocranium":[232],"and,":[233],"if":[234],"necessary,":[235],"viscerocranium.":[238],"Beyond":[239],"aesthetic":[240],"purposes,":[241],"primary":[243],"permit":[250],"development":[253],"brain.":[256]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2022-06-13T00:00:00"}