{"id":"https://openalex.org/W4281748890","doi":"https://doi.org/10.1093/stmcls/sxac040","title":"Pluripotent Stem Cells in Clinical Setting\u2014New Developments and Overview of Current Status","display_name":"Pluripotent Stem Cells in Clinical Setting\u2014New Developments and Overview of Current Status","publication_year":2022,"publication_date":"2022-06-07","ids":{"openalex":"https://openalex.org/W4281748890","doi":"https://doi.org/10.1093/stmcls/sxac040","pmid":"https://pubmed.ncbi.nlm.nih.gov/35671338","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9512105"},"language":"en","primary_location":{"id":"doi:10.1093/stmcls/sxac040","doi":"https://doi.org/10.1093/stmcls/sxac040","is_oa":true,"landing_page_url":"https://doi.org/10.1093/stmcls/sxac040","pdf_url":"https://academic.oup.com/stmcls/advance-article-pdf/doi/10.1093/stmcls/sxac040/44855179/sxac040.pdf","source":{"id":"https://openalex.org/S65139510","display_name":"Stem Cells","issn_l":"1066-5099","issn":["1066-5099","1549-4918"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cells","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/stmcls/advance-article-pdf/doi/10.1093/stmcls/sxac040/44855179/sxac040.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085747842","display_name":"Du\u0161ko Ili\u0107","orcid":"https://orcid.org/0000-0003-1647-0026","observed_orcids":["https://orcid.org/0000-0003-1647-0026"]},"institutions":[{"id":"https://openalex.org/I1298207432","display_name":"Guy's Hospital","ror":"https://ror.org/04r33pf22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1298207432","https://openalex.org/I200166805","https://openalex.org/I4210111135"]},{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Dusko Ilic","raw_affiliation_strings":["Assisted Conception Unit, Guy\u2019s Hospital , London , UK","Division of Women and Children\u2019s Health, Faculty of Life Sciences and Medicine, King\u2019s College London , London , UK"],"raw_orcid":"https://orcid.org/0000-0003-1647-0026","affiliations":[{"raw_affiliation_string":"Assisted Conception Unit, Guy\u2019s Hospital , London , UK","institution_ids":["https://openalex.org/I1298207432"]},{"raw_affiliation_string":"Division of Women and Children\u2019s Health, Faculty of Life Sciences and Medicine, King\u2019s College London , London , UK","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049601909","display_name":"Caroline Mackie Ogilvie","orcid":"https://orcid.org/0000-0001-6827-0443","observed_orcids":["https://orcid.org/0000-0001-6827-0443"]},"institutions":[{"id":"https://openalex.org/I1298207432","display_name":"Guy's Hospital","ror":"https://ror.org/04r33pf22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1298207432","https://openalex.org/I200166805","https://openalex.org/I4210111135"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Caroline Ogilvie","raw_affiliation_strings":["Genetics Laboratories, Guy\u2019s Hospital , London , UK"],"raw_orcid":"https://orcid.org/0000-0001-6827-0443","affiliations":[{"raw_affiliation_string":"Genetics Laboratories, Guy\u2019s Hospital , London , UK","institution_ids":["https://openalex.org/I1298207432"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5085747842"],"corresponding_institution_ids":["https://openalex.org/I1298207432","https://openalex.org/I183935753"],"apc_list":{"value":4140,"currency":"USD","value_usd":4140},"apc_paid":{"value":4140,"currency":"USD","value_usd":4140},"fwci":0.7034,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.60364949,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"40","issue":"9","first_page":"791","last_page":"801"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13417","display_name":"Biomedical Ethics and Regulation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-pluripotent-stem-cells","display_name":"human pluripotent stem cells","score":0.9599999785423279},{"id":"https://openalex.org/keywords/embryonic-stem-cells","display_name":"embryonic stem cells","score":0.8309999704360962},{"id":"https://openalex.org/keywords/induced-pluripotent-stem-cells","display_name":"induced pluripotent stem cells","score":1.0},{"id":"https://openalex.org/keywords/clinical-trials","display_name":"clinical trials","score":0.7870000004768372},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.7739999890327454},{"id":"https://openalex.org/keywords/degenerative-eye-diseases","display_name":"degenerative eye diseases","score":0.8980000019073486},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.8080000281333923},{"id":"https://openalex.org/keywords/genome-editing","display_name":"genome editing","score":0.8009999990463257},{"id":"https://openalex.org/keywords/nanomedicine","display_name":"nanomedicine","score":0.9049999713897705},{"id":"https://openalex.org/keywords/in-vivo-gene-therapy","display_name":"in vivo gene therapy","score":0.7879999876022339},{"id":"https://openalex.org/keywords/spinal-cord-injury","display_name":"spinal cord injury","score":0.9070000052452087},{"id":"https://openalex.org/keywords/epidural-stimulation","display_name":"epidural stimulation","score":0.9549999833106995}],"concepts":[{"id":"https://openalex.org/C107459253","wikidata":"https://www.wikidata.org/wiki/Q674925","display_name":"Induced pluripotent stem cell","level":4,"score":0.8959773778915405},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.6909396052360535},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.6278883814811707},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.595954418182373},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.509133517742157},{"id":"https://openalex.org/C10854531","wikidata":"https://www.wikidata.org/wiki/Q1061415","display_name":"Regenerative medicine","level":3,"score":0.4974112808704376},{"id":"https://openalex.org/C10882517","wikidata":"https://www.wikidata.org/wiki/Q15268054","display_name":"Cell therapy","level":3,"score":0.4882338345050812},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.4218734800815582},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4149891436100006},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3807378113269806},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.27498066425323486},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.0837288498878479},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000066449","descriptor_name":"Human Embryonic Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000066449","descriptor_name":"Human Embryonic Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000066449","descriptor_name":"Human Embryonic Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039904","descriptor_name":"Pluripotent Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D039904","descriptor_name":"Pluripotent Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D039904","descriptor_name":"Pluripotent Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057026","descriptor_name":"Induced Pluripotent Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057026","descriptor_name":"Induced Pluripotent Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057026","descriptor_name":"Induced Pluripotent Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064987","descriptor_name":"Cell- and Tissue-Based Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064987","descriptor_name":"Cell- and Tissue-Based Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064987","descriptor_name":"Cell- and Tissue-Based Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/stmcls/sxac040","doi":"https://doi.org/10.1093/stmcls/sxac040","is_oa":true,"landing_page_url":"https://doi.org/10.1093/stmcls/sxac040","pdf_url":"https://academic.oup.com/stmcls/advance-article-pdf/doi/10.1093/stmcls/sxac040/44855179/sxac040.pdf","source":{"id":"https://openalex.org/S65139510","display_name":"Stem Cells","issn_l":"1066-5099","issn":["1066-5099","1549-4918"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cells","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9512105","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9512105","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cells","raw_type":"Text"},{"id":"pmid:35671338","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35671338","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem cells (Dayton, Ohio)","raw_type":"Journal Article"},{"id":"pmh:oai:kclpure.kcl.ac.uk:openaire/a278f3a4-febb-4e5d-83b5-d6a0246c47ae","doi":null,"is_oa":true,"landing_page_url":"https://www.scopus.com/pages/publications/85138658360","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Ilic, D & Ogilvie, C 2022, 'Pluripotent Stem Cells in Clinical Setting-New Developments and Overview of Current Status', Stem cells (Dayton, Ohio), vol. 40, no. 9, pp. 791-801. https://doi.org/10.1093/stmcls/sxac040","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/stmcls/sxac040","doi":"https://doi.org/10.1093/stmcls/sxac040","is_oa":true,"landing_page_url":"https://doi.org/10.1093/stmcls/sxac040","pdf_url":"https://academic.oup.com/stmcls/advance-article-pdf/doi/10.1093/stmcls/sxac040/44855179/sxac040.pdf","source":{"id":"https://openalex.org/S65139510","display_name":"Stem Cells","issn_l":"1066-5099","issn":["1066-5099","1549-4918"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cells","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G122229918","display_name":null,"funder_award_id":"LF16028","funder_id":"https://openalex.org/F4320327561","funder_display_name":"LEO Fondet"}],"funders":[{"id":"https://openalex.org/F4320310966","display_name":"National Department of Health","ror":"https://ror.org/05rfgws98"},{"id":"https://openalex.org/F4320311196","display_name":"King\u2019s College London","ror":"https://ror.org/0220mzb33"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320285","display_name":"King's College London","ror":"https://ror.org/0220mzb33"},{"id":"https://openalex.org/F4320327561","display_name":"LEO Fondet","ror":"https://ror.org/02rgsr590"},{"id":"https://openalex.org/F4320336045","display_name":"NIHR Oxford Biomedical Research Centre","ror":"https://ror.org/00aps1a34"},{"id":"https://openalex.org/F7017704138","display_name":"Niilo Helanderin S\u00e4\u00e4ti\u00f6","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4281748890.pdf","grobid_xml":"https://content.openalex.org/works/W4281748890.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W177199058","https://openalex.org/W1983415109","https://openalex.org/W1991936258","https://openalex.org/W2000912956","https://openalex.org/W2005163476","https://openalex.org/W2062504594","https://openalex.org/W2125987139","https://openalex.org/W2136947191","https://openalex.org/W2162377851","https://openalex.org/W2206030442","https://openalex.org/W2601350462","https://openalex.org/W2616215756","https://openalex.org/W2898429451","https://openalex.org/W2948888731","https://openalex.org/W2970240057","https://openalex.org/W3041366976","https://openalex.org/W3043334872","https://openalex.org/W3089827298","https://openalex.org/W3097128992","https://openalex.org/W3118995603","https://openalex.org/W3198277215","https://openalex.org/W3200157938","https://openalex.org/W3212534710","https://openalex.org/W3214753991","https://openalex.org/W3214819015","https://openalex.org/W3215314073","https://openalex.org/W4206716689","https://openalex.org/W4207068215","https://openalex.org/W4210917455"],"related_works":["https://openalex.org/W4406073244","https://openalex.org/W2206030442","https://openalex.org/W1629446782","https://openalex.org/W2191155238","https://openalex.org/W2757032260","https://openalex.org/W2154131540","https://openalex.org/W7117321052","https://openalex.org/W1812829745","https://openalex.org/W4393410551","https://openalex.org/W2197714088"],"abstract_inverted_index":{"The":[0],"number":[1],"of":[2,29,33,72,74,81,90,99,137,150,173,183,196],"clinical":[3,128],"trials":[4,35,76,83],"using":[5],"human":[6],"pluripotent":[7,14],"stem":[8,15],"cells":[9,16],"(hPSC)-both":[10],"embryonic":[11],"and":[12,52,59,65,94,127,176,179,226],"induced":[13],"(hESC/iPSC)-has":[17],"expanded":[18],"in":[19,39,102,111,147,168,180],"the":[20,27,53,88,135,148,169,194,200,203],"last":[21],"several":[22],"years":[23],"beyond":[24],"expectations.":[25],"By":[26],"end":[28],"2021,":[30],"a":[31,144,165],"total":[32],"90":[34],"had":[36],"been":[37,122],"registered":[38,68],"13":[40],"countries":[41],"with":[42,212],"more":[43,188],"than":[44,79,190],"3000":[45],"participants.":[46],"However,":[47],"only":[48],"US,":[49,63],"Japan,":[50,64],"China,":[51],"UK":[54],"are":[55,85,130],"conducting":[56],"both":[57],"hESC-":[58],"hiPSC-based":[60],"trials.":[61,104],"Together":[62],"China":[66],"have":[67,121],"78%":[69],"(70":[70],"out":[71],"90)":[73],"all":[75,82,100],"worldwide.":[77],"More":[78],"half":[80],"(51%)":[84],"focused":[86],"on":[87],"treatment":[89,195],"degenerative":[91],"eye":[92],"diseases":[93],"malignancies,":[95],"enrolling":[96],"nearly":[97],"2/3":[98],"participants":[101],"hPSC-based":[103,117,151,206],"Although":[105],"no":[106],"serious":[107],"adverse":[108],"events":[109],"resulting":[110],"death":[112],"or":[113],"morbidity":[114],"due":[115],"to":[116,155],"cellular":[118,152,191,207],"therapy":[119,185,208],"received":[120],"reported,":[123],"information":[124],"about":[125],"safety":[126],"efficacy":[129],"still":[131],"very":[132],"limited.":[133],"With":[134],"availability":[136],"novel":[138],"technologies":[139],"for":[140,193,202],"precise":[141],"genome":[142],"editing,":[143],"new":[145],"trend":[146],"development":[149],"therapies":[153,192],"seems":[154],"be":[156,210],"emerging.":[157],"Engineering":[158],"universal":[159],"donor":[160],"hPSC":[161],"lines":[162],"has":[163],"become":[164,187],"holy":[166],"grail":[167],"field.":[170],"Indeed,":[171],"because":[172],"its":[174],"effectiveness":[175],"simplicity":[177],"nanomedicine":[178],"vivo":[181],"delivery":[182],"gene":[184],"could":[186],"advantageous":[189],"multiple":[197],"diseases.":[198],"In":[199],"future,":[201],"best":[204],"outcome,":[205],"might":[209],"combined":[211],"other":[213],"technological":[214],"advancements,":[215],"such":[216],"as":[217],"biomimetic":[218],"epidural":[219],"electrical":[220],"stimulation":[221],"that":[222],"can":[223],"restore":[224],"trunk":[225],"leg":[227],"motor":[228],"functions":[229],"after":[230],"complete":[231],"spinal":[232],"injury.":[233]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":2}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2022-06-13T00:00:00"}