{"id":"https://openalex.org/W4281677924","doi":"https://doi.org/10.19127/mbsjohs.1001931","title":"YY1 and NFYA: Potential tr-KIT Specific Transcription Factors in Prostate Cancer","display_name":"YY1 and NFYA: Potential tr-KIT Specific Transcription Factors in Prostate Cancer","publication_year":2022,"publication_date":"2022-05-28","ids":{"openalex":"https://openalex.org/W4281677924","doi":"https://doi.org/10.19127/mbsjohs.1001931"},"language":"en","primary_location":{"id":"doi:10.19127/mbsjohs.1001931","doi":"https://doi.org/10.19127/mbsjohs.1001931","is_oa":true,"landing_page_url":"https://doi.org/10.19127/mbsjohs.1001931","pdf_url":null,"source":{"id":"https://openalex.org/S4210205458","display_name":"MIDDLE BLACK SEA JOURNAL OF HEALTH SCIENCE","issn_l":"2149-7796","issn":["2149-7796"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310318383","host_organization_name":"Turkish Online Journal of Qualitative Inquiry (TOJQI)","host_organization_lineage":["https://openalex.org/P4310318383"],"host_organization_lineage_names":["Turkish Online Journal of Qualitative Inquiry (TOJQI)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Middle Black Sea Journal of Health Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.19127/mbsjohs.1001931","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087261816","display_name":"Sercan Erg\u00fcn","orcid":"https://orcid.org/0000-0002-6733-9848","observed_orcids":["https://orcid.org/0000-0002-6733-9848"]},"institutions":[{"id":"https://openalex.org/I227306068","display_name":"Ondokuz May\u0131s University","ror":"https://ror.org/028k5qw24","country_code":"TR","type":"education","lineage":["https://openalex.org/I227306068"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Sercan ERG\u00dcN","raw_affiliation_strings":["ONDOKUZ MAYIS UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF BASIC MEDICAL SCIENCES, MEDICAL DEPARTMENT OF BIOLOGY, MEDICAL BIOLOGY","of , of , , ,"],"raw_orcid":"https://orcid.org/0000-0002-6733-9848","affiliations":[{"raw_affiliation_string":"ONDOKUZ MAYIS UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF BASIC MEDICAL SCIENCES, MEDICAL DEPARTMENT OF BIOLOGY, MEDICAL BIOLOGY","institution_ids":["https://openalex.org/I227306068"]},{"raw_affiliation_string":"of , of , , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034355562","display_name":"Ferda Ar\u0131","orcid":"https://orcid.org/0000-0002-6729-7908","observed_orcids":["https://orcid.org/0000-0002-6729-7908"]},"institutions":[{"id":"https://openalex.org/I131835042","display_name":"Bursa Uluda\u011f \u00dcni\u0307versi\u0307tesi\u0307","ror":"https://ror.org/03tg3eb07","country_code":"TR","type":"education","lineage":["https://openalex.org/I131835042"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ferda ARI","raw_affiliation_strings":["BURSA ULUDAG UNIVERSITY, FACULTY OF ARTS AND SCIENCES, BIOLOGY PR","of , of"],"raw_orcid":"https://orcid.org/0000-0002-6729-7908","affiliations":[{"raw_affiliation_string":"BURSA ULUDAG UNIVERSITY, FACULTY OF ARTS AND SCIENCES, BIOLOGY PR","institution_ids":["https://openalex.org/I131835042"]},{"raw_affiliation_string":"of , of","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007374370","display_name":"Erdal Benli\u0307","orcid":"https://orcid.org/0000-0001-8485-1424","observed_orcids":["https://orcid.org/0000-0001-8485-1424"]},"institutions":[{"id":"https://openalex.org/I64957398","display_name":"Ordu University","ror":"https://ror.org/04r0hn449","country_code":"TR","type":"education","lineage":["https://openalex.org/I64957398"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Erdal BENL\u0130","raw_affiliation_strings":["ORDU UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, THE DEPARTMENT OF UROLOGY","of , of , , ,"],"raw_orcid":"https://orcid.org/0000-0001-8485-1424","affiliations":[{"raw_affiliation_string":"ORDU UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, THE DEPARTMENT OF UROLOGY","institution_ids":["https://openalex.org/I64957398"]},{"raw_affiliation_string":"of , of , , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018832634","display_name":"Diler Us Altay","orcid":"https://orcid.org/0000-0002-0465-8403","observed_orcids":["https://orcid.org/0000-0002-0465-8403"]},"institutions":[{"id":"https://openalex.org/I64957398","display_name":"Ordu University","ror":"https://ror.org/04r0hn449","country_code":"TR","type":"education","lineage":["https://openalex.org/I64957398"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Diler US ALTAY","raw_affiliation_strings":["ORDU UNIVERSITY, FACULTY OF HEALTH SCIENCES, DEPARTMENT OF NUTRITION AND DIETETICS, DEPARTMENT OF DIETETICS"],"raw_orcid":"https://orcid.org/0000-0002-0465-8403","affiliations":[{"raw_affiliation_string":"ORDU UNIVERSITY, FACULTY OF HEALTH SCIENCES, DEPARTMENT OF NUTRITION AND DIETETICS, DEPARTMENT OF DIETETICS","institution_ids":["https://openalex.org/I64957398"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055483323","display_name":"Tevfik Noyan","orcid":"https://orcid.org/0000-0002-7733-0177","observed_orcids":["https://orcid.org/0000-0002-7733-0177"]},"institutions":[{"id":"https://openalex.org/I64957398","display_name":"Ordu University","ror":"https://ror.org/04r0hn449","country_code":"TR","type":"education","lineage":["https://openalex.org/I64957398"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Tevfik NOYAN","raw_affiliation_strings":["ORDU UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF BASIC MEDICAL SCIENCES, DEPARTMENT OF BIOCHEMISTRY","of , of , , ,"],"raw_orcid":"https://orcid.org/0000-0002-7733-0177","affiliations":[{"raw_affiliation_string":"ORDU UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF BASIC MEDICAL SCIENCES, DEPARTMENT OF BIOCHEMISTRY","institution_ids":["https://openalex.org/I64957398"]},{"raw_affiliation_string":"of , of , , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007150410","display_name":"Havva Erdem","orcid":"https://orcid.org/0000-0002-3074-0240","observed_orcids":["https://orcid.org/0000-0002-3074-0240"]},"institutions":[{"id":"https://openalex.org/I64957398","display_name":"Ordu University","ror":"https://ror.org/04r0hn449","country_code":"TR","type":"education","lineage":["https://openalex.org/I64957398"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Havva ERDEM","raw_affiliation_strings":["ORDU UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF MEDICAL PATHOLOGY","of , of , , ,"],"raw_orcid":"https://orcid.org/0000-0002-3074-0240","affiliations":[{"raw_affiliation_string":"ORDU UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF MEDICAL PATHOLOGY","institution_ids":["https://openalex.org/I64957398"]},{"raw_affiliation_string":"of , of , , ,","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041380206","display_name":"Yeliz Ka\u015fko Ar\u0131c\u0131","orcid":"https://orcid.org/0000-0001-6820-0381","observed_orcids":["https://orcid.org/0000-0001-6820-0381"]},"institutions":[{"id":"https://openalex.org/I64957398","display_name":"Ordu University","ror":"https://ror.org/04r0hn449","country_code":"TR","type":"education","lineage":["https://openalex.org/I64957398"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Yeliz KA\u015eKO ARICI","raw_affiliation_strings":["ORDU UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF BASIC MEDICAL SCIENCES, DEPARTMENT OF BIOSTATISTICS","of , of , , ,"],"raw_orcid":"https://orcid.org/0000-0001-6820-0381","affiliations":[{"raw_affiliation_string":"ORDU UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF BASIC MEDICAL SCIENCES, DEPARTMENT OF BIOSTATISTICS","institution_ids":["https://openalex.org/I64957398"]},{"raw_affiliation_string":"of , of , , ,","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5087261816"],"corresponding_institution_ids":["https://openalex.org/I227306068"],"apc_list":null,"apc_paid":null,"fwci":0.1624,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.45042534,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"8","issue":"2","first_page":"202","last_page":"207"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13779","display_name":"Cancer Mechanisms and Therapy","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.9769999980926514},{"id":"https://openalex.org/keywords/yy1","display_name":"YY1","score":0.8730000257492065},{"id":"https://openalex.org/keywords/nf-ya","display_name":"NF-YA","score":1.0},{"id":"https://openalex.org/keywords/transcription-factors","display_name":"transcription factors","score":0.9459999799728394},{"id":"https://openalex.org/keywords/alternative-promoter-usage","display_name":"alternative promoters","score":0.7580000162124634},{"id":"https://openalex.org/keywords/imatinib-resistance","display_name":"imatinib resistance","score":0.7070000171661377},{"id":"https://openalex.org/keywords/c-myb","display_name":"MYB","score":0.847000002861023},{"id":"https://openalex.org/keywords/tcf3","display_name":"TCF3","score":0.8539999723434448},{"id":"https://openalex.org/keywords/interleukin-8","display_name":"interleukin-8","score":0.8640000224113464},{"id":"https://openalex.org/keywords/lncap-cells","display_name":"LNCaP cells","score":0.7870000004768372},{"id":"https://openalex.org/keywords/pc-3-cells","display_name":"PC-3 cells","score":0.8600000143051147},{"id":"https://openalex.org/keywords/rwpe-1","display_name":"RWPE-1","score":0.8519999980926514},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.8289999961853027}],"concepts":[{"id":"https://openalex.org/C2776438761","wikidata":"https://www.wikidata.org/wiki/Q5206280","display_name":"DU145","level":5,"score":0.7596416473388672},{"id":"https://openalex.org/C2779723316","wikidata":"https://www.wikidata.org/wiki/Q6459234","display_name":"LNCaP","level":4,"score":0.7416913509368896},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.6653347611427307},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.6188177466392517},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.5438471436500549},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5345600843429565},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3970746099948883},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.37802737951278687},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.32493308186531067},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2835707664489746},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24119743704795837},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.22911468148231506}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.19127/mbsjohs.1001931","doi":"https://doi.org/10.19127/mbsjohs.1001931","is_oa":true,"landing_page_url":"https://doi.org/10.19127/mbsjohs.1001931","pdf_url":null,"source":{"id":"https://openalex.org/S4210205458","display_name":"MIDDLE BLACK SEA JOURNAL OF HEALTH SCIENCE","issn_l":"2149-7796","issn":["2149-7796"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310318383","host_organization_name":"Turkish Online Journal of Qualitative Inquiry (TOJQI)","host_organization_lineage":["https://openalex.org/P4310318383"],"host_organization_lineage_names":["Turkish Online Journal of Qualitative Inquiry (TOJQI)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Middle Black Sea Journal of Health Science","raw_type":"journal-article"},{"id":"pmh:oai:dergipark.org.tr:article/1001931","doi":null,"is_oa":true,"landing_page_url":"https://dergipark.org.tr/tr/pub/mbsjohs/issue/70119/1001931","pdf_url":"https://dergipark.org.tr/tr/pub/mbsjohs/issue/70119/1001931","source":{"id":"https://openalex.org/S4306401840","display_name":"DergiPark (Istanbul University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67581229","host_organization_name":"Istanbul University","host_organization_lineage":["https://openalex.org/I67581229"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Middle Black Sea Journal of Health Science","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:fca21121-df9d-43c8-88c7-7d4ec11dfdd0","doi":null,"is_oa":false,"landing_page_url":"https://avesis.uludag.edu.tr/publication/details/fca21121-df9d-43c8-88c7-7d4ec11dfdd0/oai","pdf_url":null,"source":{"id":"https://openalex.org/S7407055210","display_name":"Bursa Uludag University - AVESIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.19127/mbsjohs.1001931","doi":"https://doi.org/10.19127/mbsjohs.1001931","is_oa":true,"landing_page_url":"https://doi.org/10.19127/mbsjohs.1001931","pdf_url":null,"source":{"id":"https://openalex.org/S4210205458","display_name":"MIDDLE BLACK SEA JOURNAL OF HEALTH SCIENCE","issn_l":"2149-7796","issn":["2149-7796"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310318383","host_organization_name":"Turkish Online Journal of Qualitative Inquiry (TOJQI)","host_organization_lineage":["https://openalex.org/P4310318383"],"host_organization_lineage_names":["Turkish Online Journal of Qualitative Inquiry (TOJQI)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Middle Black Sea Journal of Health Science","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6899999976158142}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1819605353","https://openalex.org/W1973045105","https://openalex.org/W1980748988","https://openalex.org/W2018335121","https://openalex.org/W2041415161","https://openalex.org/W2108638877","https://openalex.org/W2148468786","https://openalex.org/W2152239989","https://openalex.org/W2497334795","https://openalex.org/W2569716909","https://openalex.org/W2731417772","https://openalex.org/W2904814184","https://openalex.org/W2954597440","https://openalex.org/W2963170510"],"related_works":["https://openalex.org/W4412662017","https://openalex.org/W2148468786","https://openalex.org/W2039568244","https://openalex.org/W2031430281","https://openalex.org/W2053460531","https://openalex.org/W2065839620","https://openalex.org/W3028601498","https://openalex.org/W2790188279","https://openalex.org/W7056588699","https://openalex.org/W2167509123"],"abstract_inverted_index":{"Objective:":[0],"Via":[1,210],"the":[2,47,69,90,114,198,223],"use":[3],"of":[4,13,25,49,125,158,167,245],"an":[5],"alternative":[6],"promoter,":[7],"a":[8,27,42,241],"truncated":[9],"c-KIT":[10,51],"protein":[11],"(tr-KIT)":[12],"30-50":[14],"kDa":[15],"is":[16],"generated,":[17],"lacking":[18],"extracellular":[19],"and":[20,135,143,179,184,208,220,236],"transmembrane":[21],"domains.":[22],"Moreover,":[23],"over-expression":[24],"tr-KIT,":[26],"stronger":[28],"activator":[29],"than":[30],"c-KIT,":[31],"appears":[32],"to":[33,36,74,78,88,118,182,191,226],"be":[34,227],"specific":[35,77,94,162,229],"prostate":[37],"cancer":[38],"(PCa).":[39],"Also,":[40],"Imatinib,":[41],"tyrosine":[43],"kinase":[44],"inhibitor,":[45],"blocks":[46],"activity":[48],"full-length":[50],"but":[52],"has":[53,61],"no":[54],"effect":[55],"on":[56],"tr-KIT":[57,79,96,161,228,246],"in":[58,98,176,188,211,231,243,247],"PCa.":[59,248],"Tr-KIT":[60,101],"its":[62],"own":[63],"nuclear":[64],"factor":[65],"binding":[66,73,104,117],"site.":[67],"However,":[68],"transcription":[70],"factors":[71],"(TFs)":[72],"this":[75,119],"region":[76],"are":[80],"not":[81,132],"known":[82],"yet.":[83],"This":[84],"study":[85],"was":[86,106,216],"conducted":[87],"define":[89],"most":[91],"potential":[92,102,116,160,200,225],"TFs":[93,112,163,171,196,230,238],"for":[95,154],"via":[97],"silico":[99,212],"analysis.Methods:":[100],"TF":[103],"sequence":[105,120],"uploaded":[107],"into":[108],"Tfsitescan":[109],"database.":[110],"Five":[111,195],"with":[113],"highest":[115,199,224],"were":[121,152,193,201],"selected.":[122],"Transcriptomic":[123],"data":[124],"LNCaP":[126,178,189],"(PCa":[127,131],"expressing":[128,133],"tr-KIT),":[129],"PC3":[130,180,192],"tr-KIT)":[134],"RWPE-1":[136,183],"(normal":[137],"prostate)":[138],"cell":[139],"lines":[140],"(GSM1647378,":[141],"GSE36022":[142],"GSM738189,":[144],"respectively)":[145],"from":[146],"Gene":[147],"Expression":[148],"Omnibus":[149],"(GEO)":[150],"database":[151],"compared":[153,181,190],"gene":[155],"expression":[156,174,186],"levels":[157,175,187],"pre-defined":[159],"using":[164],"DESeq":[165],"package":[166],"R-program.":[168],"Finally,":[169],"two":[170],"having":[172,197],"higher":[173,185],"both":[177],"detected.Results:":[194],"selected":[202],"as:":[203],"YY1,":[204],"c-MYB,":[205],"IL8,":[206],"NFYA":[207,221,237],"TCF3.":[209],"analysis":[213],"performed,":[214],"it":[215],"found":[217],"that":[218],"YY1":[219,235],"have":[222],"PCa,":[232],"among":[233],"them.Conclusion:":[234],"may":[239],"take":[240],"role":[242],"formation":[244]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2026-08-31T07:19:18.363097","created_date":"2022-06-13T00:00:00"}