{"id":"https://openalex.org/W4281675686","doi":"https://doi.org/10.1080/14786419.2022.2086546","title":"A new flavonoid glycoside from Toxicodendron vernicifluum (Stokes) F.A. Barkley","display_name":"A new flavonoid glycoside from Toxicodendron vernicifluum (Stokes) F.A. Barkley","publication_year":2022,"publication_date":"2022-06-10","ids":{"openalex":"https://openalex.org/W4281675686","doi":"https://doi.org/10.1080/14786419.2022.2086546","pmid":"https://pubmed.ncbi.nlm.nih.gov/35687836"},"language":"en","primary_location":{"id":"doi:10.1080/14786419.2022.2086546","doi":"https://doi.org/10.1080/14786419.2022.2086546","is_oa":false,"landing_page_url":"https://doi.org/10.1080/14786419.2022.2086546","pdf_url":null,"source":{"id":"https://openalex.org/S205999849","display_name":"Natural Product Research","issn_l":"1478-6419","issn":["1478-6419","1478-6427"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural Product Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000509852","display_name":"Chengye Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chengye Zhao","raw_affiliation_strings":["School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China","institution_ids":["https://openalex.org/I199305430"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084453812","display_name":"Meichen Li","orcid":"https://orcid.org/0000-0003-1717-1247","observed_orcids":["https://orcid.org/0000-0003-1717-1247"]},"institutions":[{"id":"https://openalex.org/I103890011","display_name":"Shenyang Pharmaceutical University","ror":"https://ror.org/03dnytd23","country_code":"CN","type":"education","lineage":["https://openalex.org/I103890011"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Meichen Li","raw_affiliation_strings":["School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, P. R. China","institution_ids":["https://openalex.org/I103890011"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104312916","display_name":"Yuqian Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuqian Yang","raw_affiliation_strings":["School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China","institution_ids":["https://openalex.org/I199305430"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036375510","display_name":"Minni Qin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Minni Qin","raw_affiliation_strings":["School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China","institution_ids":["https://openalex.org/I199305430"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081504976","display_name":"Ruojia Wang","orcid":"https://orcid.org/0000-0003-1806-0688","observed_orcids":["https://orcid.org/0000-0003-1806-0688"]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruojia Wang","raw_affiliation_strings":["School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China","institution_ids":["https://openalex.org/I199305430"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056598643","display_name":"Qing Zhu","orcid":"https://orcid.org/0000-0002-9411-9517","observed_orcids":["https://orcid.org/0000-0002-9411-9517"]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qing Zhu","raw_affiliation_strings":["School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China","institution_ids":["https://openalex.org/I199305430"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069559042","display_name":"Guangtong Chen","orcid":"https://orcid.org/0000-0002-3274-9281","observed_orcids":["https://orcid.org/0000-0002-3274-9281"]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guangtong Chen","raw_affiliation_strings":["School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China","institution_ids":["https://openalex.org/I199305430"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101770147","display_name":"Andong Wang","orcid":"https://orcid.org/0000-0003-2281-7946","observed_orcids":["https://orcid.org/0000-0003-2281-7946"]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Andong Wang","raw_affiliation_strings":["School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China"],"raw_orcid":"https://orcid.org/0000-0003-2281-7946","affiliations":[{"raw_affiliation_string":"School of Pharmacy, Nantong University, Nantong, Jiangsu, P. R. China","institution_ids":["https://openalex.org/I199305430"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5069559042","https://openalex.org/A5101770147"],"corresponding_institution_ids":["https://openalex.org/I199305430"],"apc_list":null,"apc_paid":null,"fwci":0.3908,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.52572398,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"37","issue":"20","first_page":"3478","last_page":"3483"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.46700000762939453,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.46700000762939453,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.4657999873161316,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13221","display_name":"Biological Activity of Diterpenoids and Biflavonoids","score":0.014499999582767487,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/toxicodendron-vernicifluum","display_name":"Toxicodendron vernicifluum","score":1.0},{"id":"https://openalex.org/keywords/flavonoid-glycosides","display_name":"flavonoid glycosides","score":0.902999997138977},{"id":"https://openalex.org/keywords/new-natural-products","display_name":"new natural products","score":0.7799999713897705},{"id":"https://openalex.org/keywords/heartwood","display_name":"heartwood","score":0.8100000023841858},{"id":"https://openalex.org/keywords/anacardiaceae","display_name":"Anacardiaceae","score":0.847000002861023},{"id":"https://openalex.org/keywords/structure-elucidation","display_name":"structure elucidation","score":0.8429999947547913},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9490000009536743},{"id":"https://openalex.org/keywords/a549-cells","display_name":"A549 cells","score":0.9760000109672546},{"id":"https://openalex.org/keywords/lacquer-tree","display_name":"lacquer tree","score":0.5889999866485596}],"concepts":[{"id":"https://openalex.org/C2779054382","wikidata":"https://www.wikidata.org/wiki/Q72185287","display_name":"Flavonoid","level":3,"score":0.7259637117385864},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.7086384296417236},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7005113959312439},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4933985769748688},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.3349335193634033},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.21665549278259277},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1080/14786419.2022.2086546","doi":"https://doi.org/10.1080/14786419.2022.2086546","is_oa":false,"landing_page_url":"https://doi.org/10.1080/14786419.2022.2086546","pdf_url":null,"source":{"id":"https://openalex.org/S205999849","display_name":"Natural Product Research","issn_l":"1478-6419","issn":["1478-6419","1478-6427"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural Product Research","raw_type":"journal-article"},{"id":"pmid:35687836","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35687836","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural product research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G6097857798","display_name":null,"funder_award_id":"82071238, 81971243","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6874480100","display_name":null,"funder_award_id":"BK20200975","funder_id":"https://openalex.org/F4320322769","funder_display_name":"Natural Science Foundation of Jiangsu Province"},{"id":"https://openalex.org/G6904880712","display_name":null,"funder_award_id":"81971243","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7840169292","display_name":null,"funder_award_id":"82071238","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322769","display_name":"Natural Science Foundation of Jiangsu Province","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W314008413","https://openalex.org/W1861107318","https://openalex.org/W2044982446","https://openalex.org/W2136277025","https://openalex.org/W2149837490","https://openalex.org/W2326764763","https://openalex.org/W2346705677","https://openalex.org/W2914414871","https://openalex.org/W2914991904","https://openalex.org/W2935449907","https://openalex.org/W2973579204","https://openalex.org/W3092780231","https://openalex.org/W3097824365","https://openalex.org/W3120379057","https://openalex.org/W3155748206","https://openalex.org/W3169641842","https://openalex.org/W4200432634"],"related_works":["https://openalex.org/W2044982446","https://openalex.org/W3007802844","https://openalex.org/W4412964875","https://openalex.org/W7170133168","https://openalex.org/W7085766119","https://openalex.org/W2581645226","https://openalex.org/W1937117991","https://openalex.org/W2997959202","https://openalex.org/W2949560873","https://openalex.org/W4299499888"],"abstract_inverted_index":{"Toxicodendron":[0],"vernicifluum":[1],"(Stokes)":[2],"F.A.":[3],"Barkley,":[4],"also":[5],"called":[6],"\u2018Qishu\u2019,":[7],"is":[8],"a":[9,22],"shrub":[10],"belonging":[11],"to":[12],"the":[13,30,44,53,71],"Anacardiaceae":[14],"family":[15],"and":[16,58],"producing":[17],"lacquer.":[18],"In":[19],"this":[20],"work,":[21],"new":[23,45],"flavonoid":[24],"glycoside":[25],"(1),":[26,51],"was":[27,47],"isolated":[28],"from":[29],"heartwood":[31],"of":[32,43,55,73],"T.":[33],"vernicifluum,":[34],"together":[35],"with":[36,70],"four":[37],"known":[38],"compounds":[39],"(2-5).":[40],"The":[41],"structure":[42],"compound":[46],"determined":[48],"as":[49],"4\u2032,7-dihydroxy-3\u2032-methoxy-3-O-\u03b2-D-glucopyranosyl-flavonoid":[50],"on":[52],"basis":[54],"acidic":[56],"hydrolysis,":[57],"spectroscopic":[59],"analyses.":[60],"Compound":[61],"1":[62],"showed":[63],"significantly":[64],"cytotoxic":[65],"against":[66],"A549":[67],"cell":[68],"lines":[69],"values":[72],"IC50":[74],"at":[75],"1.5":[76],"\u03bcM.":[77]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2022-06-13T00:00:00"}