{"id":"https://openalex.org/W4281558071","doi":"https://doi.org/10.1097/pts.0000000000001039","title":"Lessons Learned in Implementing a Chronic Opioid Therapy Management System","display_name":"Lessons Learned in Implementing a Chronic Opioid Therapy Management System","publication_year":2022,"publication_date":"2022-05-26","ids":{"openalex":"https://openalex.org/W4281558071","doi":"https://doi.org/10.1097/pts.0000000000001039","pmid":"https://pubmed.ncbi.nlm.nih.gov/35617623","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9691784"},"language":"en","primary_location":{"id":"doi:10.1097/pts.0000000000001039","doi":"https://doi.org/10.1097/pts.0000000000001039","is_oa":false,"landing_page_url":"https://doi.org/10.1097/pts.0000000000001039","pdf_url":null,"source":{"id":"https://openalex.org/S29620287","display_name":"Journal of Patient Safety","issn_l":"1549-8417","issn":["1549-8417","1549-8425"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Patient Safety","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9691784","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089998655","display_name":"Narath Carlile","orcid":"https://orcid.org/0000-0002-6601-6035","observed_orcids":["https://orcid.org/0000-0002-6601-6035"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Narath Carlile","raw_affiliation_strings":["Center for","Center for Patient Safety Research and Practice, Brigham and Women\u2019s Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for","institution_ids":[]},{"raw_affiliation_string":"Center for Patient Safety Research and Practice, Brigham and Women\u2019s Hospital","institution_ids":["https://openalex.org/I1283280774"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024320373","display_name":"Theresa E. Fuller","orcid":"https://orcid.org/0000-0002-1358-854X","observed_orcids":["https://orcid.org/0000-0002-1358-854X"]},"institutions":[{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Theresa E. Fuller","raw_affiliation_strings":["Healthcare Systems Engineering Institute, Northeastern University, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Healthcare Systems Engineering Institute, Northeastern University, Boston, Massachusetts","institution_ids":["https://openalex.org/I12912129"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074360961","display_name":"James C. Benneyan","orcid":"https://orcid.org/0000-0003-0070-9709","observed_orcids":["https://orcid.org/0000-0003-0070-9709"]},"institutions":[{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James C. Benneyan","raw_affiliation_strings":["Healthcare Systems Engineering Institute, Northeastern University, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Healthcare Systems Engineering Institute, Northeastern University, Boston, Massachusetts","institution_ids":["https://openalex.org/I12912129"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034892054","display_name":"Basma Bargal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Basma Bargal","raw_affiliation_strings":["Healthcare Systems Engineering Institute, Northeastern University, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Healthcare Systems Engineering Institute, Northeastern University, Boston, Massachusetts","institution_ids":["https://openalex.org/I12912129"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041209043","display_name":"Lindsay Swain Hunt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lindsay Hunt","raw_affiliation_strings":["Center for","Center for Patient Safety Research and Practice, Brigham and Women\u2019s Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for","institution_ids":[]},{"raw_affiliation_string":"Center for Patient Safety Research and Practice, Brigham and Women\u2019s Hospital","institution_ids":["https://openalex.org/I1283280774"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033547979","display_name":"Sara J. Singer","orcid":"https://orcid.org/0000-0002-3374-1177","observed_orcids":["https://orcid.org/0000-0002-3374-1177"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sara Singer","raw_affiliation_strings":["Center for","Sara Singer, MBA, PhD, Stanford University School of Medicine, 1265 Welch Rd, MSOB Rm 328, Stanford, CA 94305 (e-mail: [email\u00a0protected])","Stanford University School of Medicine, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for","institution_ids":[]},{"raw_affiliation_string":"Sara Singer, MBA, PhD, Stanford University School of Medicine, 1265 Welch Rd, MSOB Rm 328, Stanford, CA 94305 (e-mail: [email\u00a0protected])","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University School of Medicine, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068708746","display_name":"Gordon D. Schiff","orcid":"https://orcid.org/0000-0002-2821-3994","observed_orcids":["https://orcid.org/0000-0002-2821-3994"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Gordon D. Schiff","raw_affiliation_strings":["Center for","Center for Patient Safety Research and Practice, Brigham and Women\u2019s Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for","institution_ids":[]},{"raw_affiliation_string":"Center for Patient Safety Research and Practice, Brigham and Women\u2019s Hospital","institution_ids":["https://openalex.org/I1283280774"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5041209043","https://openalex.org/A5068708746","https://openalex.org/A5089998655"],"corresponding_institution_ids":["https://openalex.org/I1283280774"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.07008171,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"18","issue":"8","first_page":"e1142","last_page":"e1149"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10508","display_name":"Patient Safety and Medication Errors","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/3604","display_name":"Emergency Medical Services"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-term-opioid-therapy","display_name":"long-term opioid therapy","score":0.972000002861023},{"id":"https://openalex.org/keywords/opioid-misuse","display_name":"opioid misuse","score":0.6100000143051147},{"id":"https://openalex.org/keywords/primary-care","display_name":"primary care","score":0.6949999928474426},{"id":"https://openalex.org/keywords/urine-drug-testing","display_name":"urine drug testing","score":0.9800000190734863},{"id":"https://openalex.org/keywords/implementation-barriers","display_name":"implementation barriers","score":0.7139999866485596},{"id":"https://openalex.org/keywords/lessons-learned","display_name":"lessons learned","score":0.6610000133514404},{"id":"https://openalex.org/keywords/iterative-improvement","display_name":"iterative improvement","score":0.5789999961853027},{"id":"https://openalex.org/keywords/systems-engineering","display_name":"systems engineering","score":0.6320000290870667},{"id":"https://openalex.org/keywords/covid-19-pandemic-disruption","display_name":"COVID-19 pandemic disruption","score":0.8050000071525574}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6874665021896362},{"id":"https://openalex.org/C2776654903","wikidata":"https://www.wikidata.org/wiki/Q2601463","display_name":"SAFER","level":2,"score":0.6543494462966919},{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.5202028155326843},{"id":"https://openalex.org/C2781063702","wikidata":"https://www.wikidata.org/wiki/Q427523","display_name":"Opioid","level":3,"score":0.4603850841522217},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.4571601450443268},{"id":"https://openalex.org/C2779418921","wikidata":"https://www.wikidata.org/wiki/Q1639178","display_name":"Opioid use disorder","level":4,"score":0.4510546922683716},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.3872091472148895},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3761429786682129},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.37306246161460876},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.12432673573493958},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000701","descriptor_name":"Analgesics, Opioid","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009293","descriptor_name":"Opioid-Related Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009293","descriptor_name":"Opioid-Related Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D009293","descriptor_name":"Opioid-Related Disorders","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D010818","descriptor_name":"Practice Patterns, Physicians'","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059350","descriptor_name":"Chronic Pain","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D059350","descriptor_name":"Chronic Pain","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1097/pts.0000000000001039","doi":"https://doi.org/10.1097/pts.0000000000001039","is_oa":false,"landing_page_url":"https://doi.org/10.1097/pts.0000000000001039","pdf_url":null,"source":{"id":"https://openalex.org/S29620287","display_name":"Journal of Patient Safety","issn_l":"1549-8417","issn":["1549-8417","1549-8425"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Patient Safety","raw_type":"journal-article"},{"id":"pmid:35617623","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35617623","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of patient safety","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9691784","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9691784","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Patient Saf","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:9691784","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9691784","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Patient Saf","raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4484286899","display_name":null,"funder_award_id":"P30 HS024453","funder_id":"https://openalex.org/F4320332177","funder_display_name":"Agency for Healthcare Research and Quality"}],"funders":[{"id":"https://openalex.org/F4320332177","display_name":"Agency for Healthcare Research and Quality","ror":"https://ror.org/03jmfdf59"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1757854360","https://openalex.org/W2004478570","https://openalex.org/W2077109204","https://openalex.org/W2085808321","https://openalex.org/W2104532571","https://openalex.org/W2118907952","https://openalex.org/W2163767758","https://openalex.org/W2296986887","https://openalex.org/W2346998625","https://openalex.org/W2520311411","https://openalex.org/W2591605610","https://openalex.org/W2749895937","https://openalex.org/W2750738858","https://openalex.org/W2785967556","https://openalex.org/W2864155196","https://openalex.org/W2906591149","https://openalex.org/W2914808079","https://openalex.org/W2945674751","https://openalex.org/W2949838749","https://openalex.org/W3087301383","https://openalex.org/W3087681663","https://openalex.org/W3137211686","https://openalex.org/W6687957736"],"related_works":["https://openalex.org/W3119679773","https://openalex.org/W2993702040","https://openalex.org/W889745753","https://openalex.org/W3022399292","https://openalex.org/W4206028010","https://openalex.org/W2898650931","https://openalex.org/W2793055381","https://openalex.org/W2998841060","https://openalex.org/W2061809306","https://openalex.org/W4396674102"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Opioid":[1],"misuse":[2],"has":[3],"resulted":[4],"in":[5,10,22,51,160,233],"significant":[6],"morbidity":[7],"and":[8,14,39,61,82,111,116,125,138,158,210,231,248],"mortality":[9],"the":[11,23,132,161,199,206,218],"United":[12],"States,":[13],"safer":[15,46],"opioid":[16,48,100,108,178,208,226],"use":[17,101],"represents":[18],"an":[19,52,66],"important":[20],"challenge":[21],"primary":[24,54,162,224],"care":[25,55,163,225],"setting.":[26],"This":[27],"article":[28],"describes":[29],"a":[30,88,149,186,234,240],"research":[31],"collaborative":[32],"of":[33,104,134,151,239],"health":[34],"service":[35],"researchers,":[36],"systems":[37,83],"engineers,":[38],"clinicians":[40,168],"seeking":[41],"to":[42,118,156,250],"improve":[43,119],"processes":[44,117],"for":[45,92,198],"chronic":[47,95,177],"therapy":[49,179],"management":[50,232],"academic":[53],"center.":[56],"We":[57,181],"present":[58],"implementation":[59],"results":[60],"lessons":[62,139],"learned":[63,140],"along":[64,213],"with":[65,106,136,214],"intervention":[67],"toolkit":[68],"that":[69],"others":[70],"may":[71],"consider":[72],"using":[73],"within":[74],"their":[75,176],"organization.":[76],"METHODS:":[77],"Using":[78],"iterative":[79],"improvement":[80],"lifecycles":[81],"engineering":[84],"principles,":[85],"we":[86],"developed":[87],"risk-based":[89,241],"workflow":[90],"model":[91],"patients":[93,105,157,184],"on":[94],"opioids.":[96],"Two":[97],"key":[98],"safe":[99],"process":[102,190],"metrics-percent":[103],"recent":[107],"treatment":[109],"agreements":[110],"urine":[112],"drug":[113],"tests-were":[114],"identified,":[115],"these":[120],"measures":[121,191],"were":[122,129],"designed,":[123],"tested,":[124],"implemented.":[126],"Focus":[127],"groups":[128],"conducted":[130],"after":[131],"conclusion":[133],"implementation,":[135],"barriers":[137],"identified":[141],"via":[142],"thematic":[143],"analysis.":[144],"RESULTS:":[145],"Initial":[146],"surveys":[147],"revealed":[148],"lack":[150],"knowledge":[152],"regarding":[153],"resources":[154],"available":[155],"prescribers":[159],"clinic.":[164],"In":[165],"addition,":[166],"18":[167],"(69%)":[169],"reported":[170],"largely":[171],"\"inheriting\"":[172],"(rather":[173],"than":[174],"initiating)":[175],"patients.":[180],"tracked":[182],"68":[183],"over":[185],"4-year":[187],"period.":[188],"Although":[189],"improved,":[192],"full":[193],"adherence":[194],"was":[195],"not":[196],"achieved":[197],"entire":[200],"population.":[201],"Barriers":[202],"included":[203],"team":[204],"structure,":[205],"evolving":[207],"environment,":[209],"surveillance":[211],"challenges,":[212],"disruptions":[215],"resulting":[216],"from":[217],"2019":[219],"novel":[220],"coronavirus.":[221],"CONCLUSIONS:":[222],"Safe":[223],"prescribing":[227],"requires":[228,246],"ongoing":[229],"monitoring":[230],"complex":[235],"environment.":[236],"The":[237],"application":[238],"approach":[242],"is":[243],"possible":[244],"but":[245],"adaptability":[247],"redundancies":[249],"be":[251],"reliable.":[252]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-05-27T00:00:00"}