{"id":"https://openalex.org/W4281476529","doi":"https://doi.org/10.2196/37480","title":"Durability of the Treatment Effects of an 8-Week Self-administered Home-Based Virtual Reality Program for Chronic Low Back Pain: 6-Month Follow-up Study of a Randomized Clinical Trial","display_name":"Durability of the Treatment Effects of an 8-Week Self-administered Home-Based Virtual Reality Program for Chronic Low Back Pain: 6-Month Follow-up Study of a Randomized Clinical Trial","publication_year":2022,"publication_date":"2022-05-25","ids":{"openalex":"https://openalex.org/W4281476529","doi":"https://doi.org/10.2196/37480","pmid":"https://pubmed.ncbi.nlm.nih.gov/35612905","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9177046"},"language":"en","primary_location":{"id":"doi:10.2196/37480","doi":"https://doi.org/10.2196/37480","is_oa":true,"landing_page_url":"https://doi.org/10.2196/37480","pdf_url":null,"source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.2196/37480","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Laura Garcia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405267143","display_name":"AppliedVR Inc. (United States)","ror":"https://ror.org/01chyqs65","country_code":"US","type":"company","lineage":["https://openalex.org/I4405267143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura Garcia","raw_affiliation_strings":["AppliedVR, Van Nuys, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AppliedVR, Van Nuys, CA, United States","institution_ids":["https://openalex.org/I4405267143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064206427","display_name":"Brandon J. Birckhead","orcid":"https://orcid.org/0000-0002-5822-7318","observed_orcids":["https://orcid.org/0000-0002-5822-7318"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brandon Birckhead","raw_affiliation_strings":["Johns Hopkins School of Medicine, Baltimore, MD, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins School of Medicine, Baltimore, MD, United States","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048477883","display_name":"Parthasarathy Krishnamurthy","orcid":"https://orcid.org/0000-0001-8924-0542","observed_orcids":["https://orcid.org/0000-0001-8924-0542"]},"institutions":[{"id":"https://openalex.org/I44461941","display_name":"University of Houston","ror":"https://ror.org/048sx0r50","country_code":"US","type":"education","lineage":["https://openalex.org/I44461941"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Parthasarathy Krishnamurthy","raw_affiliation_strings":["University of Houston, Houston, TX, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Houston, Houston, TX, United States","institution_ids":["https://openalex.org/I44461941"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086663769","display_name":"Ian G. Mackey","orcid":"https://orcid.org/0000-0002-7691-1041","observed_orcids":["https://orcid.org/0000-0002-7691-1041"]},"institutions":[{"id":"https://openalex.org/I4405267143","display_name":"AppliedVR Inc. (United States)","ror":"https://ror.org/01chyqs65","country_code":"US","type":"company","lineage":["https://openalex.org/I4405267143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ian Mackey","raw_affiliation_strings":["AppliedVR, Van Nuys, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AppliedVR, Van Nuys, CA, United States","institution_ids":["https://openalex.org/I4405267143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039228072","display_name":"Josh Sackman","orcid":"https://orcid.org/0000-0001-8564-6211","observed_orcids":["https://orcid.org/0000-0001-8564-6211"]},"institutions":[{"id":"https://openalex.org/I4405267143","display_name":"AppliedVR Inc. (United States)","ror":"https://ror.org/01chyqs65","country_code":"US","type":"company","lineage":["https://openalex.org/I4405267143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua Sackman","raw_affiliation_strings":["AppliedVR, Van Nuys, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AppliedVR, Van Nuys, CA, United States","institution_ids":["https://openalex.org/I4405267143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022953810","display_name":"Vafi Salmasi","orcid":"https://orcid.org/0000-0002-1288-4531","observed_orcids":["https://orcid.org/0000-0002-1288-4531"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vafi Salmasi","raw_affiliation_strings":["Stanford University School of Medicine, Palo Alto, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford University School of Medicine, Palo Alto, CA, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013753843","display_name":"Robert G. Louis","orcid":"https://orcid.org/0000-0003-4420-602X","observed_orcids":["https://orcid.org/0000-0003-4420-602X"]},"institutions":[{"id":"https://openalex.org/I1307629703","display_name":"Hoag Memorial Hospital Presbyterian","ror":"https://ror.org/05nmfef18","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1307629703"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Louis","raw_affiliation_strings":["Hoag Memorial Hospital, Newport Beach, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hoag Memorial Hospital, Newport Beach, CA, United States","institution_ids":["https://openalex.org/I1307629703"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062729801","display_name":"Carina Castro","orcid":"https://orcid.org/0000-0002-2171-9984","observed_orcids":["https://orcid.org/0000-0002-2171-9984"]},"institutions":[{"id":"https://openalex.org/I4405267143","display_name":"AppliedVR Inc. (United States)","ror":"https://ror.org/01chyqs65","country_code":"US","type":"company","lineage":["https://openalex.org/I4405267143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carina Castro","raw_affiliation_strings":["AppliedVR, Van Nuys, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AppliedVR, Van Nuys, CA, United States","institution_ids":["https://openalex.org/I4405267143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075204440","display_name":"Roselani Maddox","orcid":"https://orcid.org/0000-0001-6899-2825","observed_orcids":["https://orcid.org/0000-0001-6899-2825"]},"institutions":[{"id":"https://openalex.org/I4405267143","display_name":"AppliedVR Inc. (United States)","ror":"https://ror.org/01chyqs65","country_code":"US","type":"company","lineage":["https://openalex.org/I4405267143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roselani Maddox","raw_affiliation_strings":["AppliedVR, Van Nuys, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AppliedVR, Van Nuys, CA, United States","institution_ids":["https://openalex.org/I4405267143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086141718","display_name":"Todd Maddox","orcid":"https://orcid.org/0000-0003-1265-4960","observed_orcids":["https://orcid.org/0000-0003-1265-4960"]},"institutions":[{"id":"https://openalex.org/I4405267143","display_name":"AppliedVR Inc. (United States)","ror":"https://ror.org/01chyqs65","country_code":"US","type":"company","lineage":["https://openalex.org/I4405267143"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Todd Maddox","raw_affiliation_strings":["AppliedVR, Van Nuys, CA, United States"],"raw_orcid":"https://orcid.org/0000-0003-1265-4960","affiliations":[{"raw_affiliation_string":"AppliedVR, Van Nuys, CA, United States","institution_ids":["https://openalex.org/I4405267143"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062641498","display_name":"Beth D. Darnall","orcid":"https://orcid.org/0000-0003-3590-511X","observed_orcids":["https://orcid.org/0000-0003-3590-511X"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Beth Darnall","raw_affiliation_strings":["Stanford School of Medicine, Palo Alto, CA, United States"],"raw_orcid":"https://orcid.org/0000-0003-3590-511X","affiliations":[{"raw_affiliation_string":"Stanford School of Medicine, Palo Alto, CA, United States","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5086141718"],"corresponding_institution_ids":["https://openalex.org/I4405267143"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":10.9327,"has_fulltext":true,"cited_by_count":48,"citation_normalized_percentile":{"value":0.99207722,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"24","issue":"5","first_page":"e37480","last_page":"e37480"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation","score":0.6646000146865845,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation","score":0.6646000146865845,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10648","display_name":"Virtual Reality Applications and Impacts","score":0.20190000534057617,"subfield":{"id":"https://openalex.org/subfields/1709","display_name":"Human-Computer Interaction"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11840","display_name":"Pain Management and Treatment","score":0.09529999643564224,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-low-back-pain","display_name":"chronic low back pain","score":0.9390000104904175},{"id":"https://openalex.org/keywords/immersive-virtual-reality","display_name":"immersive virtual reality","score":0.7590000033378601},{"id":"https://openalex.org/keywords/home-based-pain-management","display_name":"home-based pain management","score":0.7860000133514404},{"id":"https://openalex.org/keywords/treatment-durability","display_name":"treatment durability","score":0.5529999732971191},{"id":"https://openalex.org/keywords/pain-intensity","display_name":"pain intensity","score":0.765999972820282},{"id":"https://openalex.org/keywords/pain-interference","display_name":"pain interference","score":0.9480000138282776},{"id":"https://openalex.org/keywords/sleep-disturbance","display_name":"sleep disorders","score":0.8700000047683716},{"id":"https://openalex.org/keywords/physical-functioning","display_name":"physical function","score":0.8859999775886536},{"id":"https://openalex.org/keywords/stress","display_name":"stress","score":0.43700000643730164},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.503000020980835},{"id":"https://openalex.org/keywords/motion-sickness","display_name":"motion sickness","score":0.8669999837875366},{"id":"https://openalex.org/keywords/nausea","display_name":"nausea","score":0.5460000038146973},{"id":"https://openalex.org/keywords/self-administered-intervention","display_name":"self-administered intervention","score":0.5619999766349792},{"id":"https://openalex.org/keywords/community-dwelling-adults","display_name":"community-dwelling adults","score":0.5640000104904175}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7077854871749878},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.6336650848388672},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.6174252033233643},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6126007437705994},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5731171369552612},{"id":"https://openalex.org/C1513209611","wikidata":"https://www.wikidata.org/wiki/Q177190","display_name":"Sleep disorder","level":3,"score":0.490313321352005},{"id":"https://openalex.org/C2781118164","wikidata":"https://www.wikidata.org/wiki/Q1088113","display_name":"Chronic pain","level":2,"score":0.44054752588272095},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4305305480957031},{"id":"https://openalex.org/C2910959060","wikidata":"https://www.wikidata.org/wiki/Q3527308","display_name":"Virtual Reality Exposure Therapy","level":3,"score":0.414816677570343},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.3813624382019043},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.20750689506530762},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.13792860507965088},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.11590608954429626},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11465921998023987},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.08874642848968506},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.07641661167144775},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000076142","descriptor_name":"Virtual Reality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012893","descriptor_name":"Sleep Wake Disorders","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D017116","descriptor_name":"Low Back Pain","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D059408","descriptor_name":"Pain Management","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.2196/37480","doi":"https://doi.org/10.2196/37480","is_oa":true,"landing_page_url":"https://doi.org/10.2196/37480","pdf_url":null,"source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},{"id":"doi:10.2196/preprints.37480","doi":"https://doi.org/10.2196/preprints.37480","is_oa":true,"landing_page_url":"https://doi.org/10.2196/preprints.37480","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"doi:10.2139/ssrn.4038205","doi":"https://doi.org/10.2139/ssrn.4038205","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.4038205","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:9177046","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9177046/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9177046/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Med Internet Res","raw_type":"Text"},{"id":"pmid:35612905","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35612905","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medical Internet research","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:3313d61e15144e61b09743f99d5a5f71","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/3313d61e15144e61b09743f99d5a5f71","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Medical Internet Research, Vol 24, Iss 5, p e37480 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.2196/37480","doi":"https://doi.org/10.2196/37480","is_oa":true,"landing_page_url":"https://doi.org/10.2196/37480","pdf_url":null,"source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4281476529.pdf","grobid_xml":"https://content.openalex.org/works/W4281476529.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W12526583","https://openalex.org/W1881181639","https://openalex.org/W1966892791","https://openalex.org/W1975558470","https://openalex.org/W2042777265","https://openalex.org/W2053601856","https://openalex.org/W2130442768","https://openalex.org/W2137070227","https://openalex.org/W2160662805","https://openalex.org/W2485262756","https://openalex.org/W2531892847","https://openalex.org/W2618758499","https://openalex.org/W2791276743","https://openalex.org/W2890078666","https://openalex.org/W2890341910","https://openalex.org/W2896422961","https://openalex.org/W2905699174","https://openalex.org/W2955599831","https://openalex.org/W2967545880","https://openalex.org/W3011255466","https://openalex.org/W3023157841","https://openalex.org/W3111934264","https://openalex.org/W3119643745","https://openalex.org/W3211537060","https://openalex.org/W4200019418","https://openalex.org/W4235080119","https://openalex.org/W4236970569"],"related_works":["https://openalex.org/W4214533023","https://openalex.org/W4200019418","https://openalex.org/W4402326413","https://openalex.org/W4387925058","https://openalex.org/W3119643745","https://openalex.org/W3111934264","https://openalex.org/W4379388343","https://openalex.org/W7112922782","https://openalex.org/W7129080934","https://openalex.org/W4377605744"],"abstract_inverted_index":{"Background":[0],"We":[1],"previously":[2],"reported":[3],"the":[4,58,121,170],"efficacy":[5],"of":[6,60,125,130,247,281],"an":[7],"8-week":[8,291],"home-based":[9,131,292],"therapeutic":[10,40,61,89,132],"immersive":[11,39],"virtual":[12],"reality":[13],"(VR)":[14],"program":[15,45,296],"in":[16,156,300,315],"a":[17,37,49,157,161],"double-blind":[18],"randomized":[19,31],"placebo-controlled":[20],"study.":[21],"Community-based":[22],"adults":[23],"with":[24,72,100,181,230,265],"self-reported":[25],"chronic":[26],"low":[27],"back":[28],"pain":[29,41,68,95,176,225,294,301],"were":[30,136,154,175,193,259],"1:1":[32],"to":[33,119,164,220,261,277,306],"receive":[34],"either":[35],"(1)":[36],"56-day":[38,50],"relief":[42],"skills":[43],"VR":[44,52,62,65,90,207,222,251,293],"(EaseVRx)":[46],"or":[47],"(2)":[48],"sham":[51,64,221,250],"program.":[53],"Immediate":[54],"posttreatment":[55,118,142,216],"results":[56],"revealed":[57],"superiority":[59,92,246],"over":[63,249],"for":[66,93,151,166,223,239],"reducing":[67,94,224],"intensity;":[69],"pain-related":[70,98,179,228],"interference":[71,99,180,229,304],"activity,":[73,101,182,231],"mood,":[74,183],"and":[75,82,97,103,112,127,141,147,178,185,202,210,217,227,233,242,254,286,303],"stress":[76],"(but":[77],"not":[78],"sleep);":[79],"physical":[80,203,240],"function;":[81],"sleep":[83,104,186,200,234,243],"disturbance.":[84],"At":[85],"3":[86],"months":[87,117,143,189,215,308],"posttreatment,":[88],"maintained":[91,208],"intensity":[96,177,226,302],"stress,":[102,184,232],"(new":[105],"finding).":[106],"Objective":[107],"This":[108],"study":[109,263,275],"assessed":[110],"between-group":[111],"within-group":[113],"treatment":[114],"effects":[115,213],"6":[116,188,214,307],"determine":[120],"extended":[122],"efficacy,":[123,126],"magnitude":[124],"clinical":[128],"importance":[129],"VR.":[133],"Methods":[134],"E-surveys":[135],"deployed":[137],"at":[138,187],"pretreatment,":[139],"end-of-treatment,":[140],"1,":[144],"2,":[145],"3,":[146],"6.":[148],"Self-reported":[149],"data":[150],"188":[152],"participants":[153,273],"analyzed":[155],"mixed-model":[158],"framework":[159],"using":[160],"marginal":[162],"model":[163],"allow":[165],"correlated":[167],"responses":[168],"across":[169],"repeated":[171],"measures.":[172],"Primary":[173],"outcomes":[174,192],"posttreatment.":[190],"Secondary":[191],"Patient-Reported":[194],"Outcome":[195],"Measurement":[196],"Information":[197],"System":[198],"(PROMIS)":[199],"disturbance":[201,244],"function.":[204],"Results":[205],"Therapeutic":[206],"significant":[209],"clinically":[211],"meaningful":[212],"remained":[218],"superior":[219],"(ds=0.44-0.54;":[235],"P<.003).":[236],"Between-group":[237],"comparisons":[238],"function":[241],"showed":[245],"EaseVRx":[248],"(ds=0.34;":[252],"P=.02":[253],"ds=0.46;":[255],"P<.001,":[256],"respectively).":[257],"Participants":[258],"encouraged":[260],"contact":[262],"staff":[264,276],"any":[266,282],"problems":[267],"experienced":[268],"during":[269],"treatment;":[270],"however,":[271],"no":[272],"contacted":[274],"report":[278],"adverse":[279],"events":[280],"type,":[283],"including":[284],"nausea":[285],"motion":[287],"sickness.":[288],"Conclusions":[289],"Our":[290],"management":[295],"caused":[297],"important":[298],"reductions":[299],"up":[305],"after":[309],"treatment.":[310],"Additional":[311],"studies":[312],"are":[313],"needed":[314],"diverse":[316],"samples.":[317],"Trial":[318],"Registration":[319],"ClinicalTrials.gov":[320],"NCT04415177;":[321],"https://clinicaltrials.gov/ct2/show/NCT04415177":[322],"International":[323],"Registered":[324],"Report":[325],"Identifier":[326],"(IRRID)":[327],"RR2-10.2196/25291":[328]},"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":6}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2022-05-26T00:00:00"}