{"id":"https://openalex.org/W4281288091","doi":"https://doi.org/10.3389/fbioe.2022.878843","title":"Extremophilic Bacterium Halomonas desertis G11 as a Cell Factory for Poly-3-Hydroxybutyrate-co-3-Hydroxyvalerate Copolymer\u2019s Production","display_name":"Extremophilic Bacterium Halomonas desertis G11 as a Cell Factory for Poly-3-Hydroxybutyrate-co-3-Hydroxyvalerate Copolymer\u2019s Production","publication_year":2022,"publication_date":"2022-05-23","ids":{"openalex":"https://openalex.org/W4281288091","doi":"https://doi.org/10.3389/fbioe.2022.878843","pmid":"https://pubmed.ncbi.nlm.nih.gov/35677302","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9168272"},"language":"en","primary_location":{"id":"doi:10.3389/fbioe.2022.878843","doi":"https://doi.org/10.3389/fbioe.2022.878843","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2022.878843","pdf_url":"https://www.frontiersin.org/articles/10.3389/fbioe.2022.878843/pdf","source":{"id":"https://openalex.org/S2595131146","display_name":"Frontiers in Bioengineering and Biotechnology","issn_l":"2296-4185","issn":["2296-4185"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioengineering and Biotechnology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fbioe.2022.878843/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048501109","display_name":"Khouloud Hammami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Khouloud Hammami","raw_affiliation_strings":["BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia","institution_ids":["https://openalex.org/I83259278"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051256512","display_name":"Yasmine Souissi","orcid":"https://orcid.org/0000-0003-3435-3165","observed_orcids":["https://orcid.org/0000-0003-3435-3165"]},"institutions":[{"id":"https://openalex.org/I39706905","display_name":"German University of Technology","ror":"https://ror.org/055hq4920","country_code":"OM","type":"education","lineage":["https://openalex.org/I39706905"]},{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["OM","TN"],"is_corresponding":false,"raw_author_name":"Yasmine Souissi","raw_affiliation_strings":["BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia","Department of Engineering, German University of Technology in Oman, Muscat, Oman"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia","institution_ids":["https://openalex.org/I83259278"]},{"raw_affiliation_string":"Department of Engineering, German University of Technology in Oman, Muscat, Oman","institution_ids":["https://openalex.org/I39706905"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022198667","display_name":"Amal Souii","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Amal Souii","raw_affiliation_strings":["BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia","institution_ids":["https://openalex.org/I83259278"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007146858","display_name":"Awatef Ouertani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Awatef Ouertani","raw_affiliation_strings":["BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia","institution_ids":["https://openalex.org/I83259278"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026633175","display_name":"Darine El Hidri","orcid":"https://orcid.org/0000-0003-3003-3682","observed_orcids":["https://orcid.org/0000-0003-3003-3682"]},"institutions":[{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Darine El-Hidri","raw_affiliation_strings":["BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia","institution_ids":["https://openalex.org/I83259278"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Marwa Jabberi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Marwa Jabberi","raw_affiliation_strings":["BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia","institution_ids":["https://openalex.org/I83259278"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020086092","display_name":"Habib Chouchane","orcid":"https://orcid.org/0000-0002-6310-3758","observed_orcids":["https://orcid.org/0000-0002-6310-3758"]},"institutions":[{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Habib Chouchane","raw_affiliation_strings":["BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia","institution_ids":["https://openalex.org/I83259278"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082125063","display_name":"Amor Mosbah","orcid":"https://orcid.org/0000-0001-5642-8805","observed_orcids":["https://orcid.org/0000-0001-5642-8805"]},"institutions":[{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Amor Mosbah","raw_affiliation_strings":["BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia","institution_ids":["https://openalex.org/I83259278"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053623432","display_name":"Ahmed Slaheddine Masmoudi","orcid":"https://orcid.org/0000-0003-4890-7173","observed_orcids":["https://orcid.org/0000-0003-4890-7173"]},"institutions":[{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Ahmed Slaheddine Masmoudi","raw_affiliation_strings":["BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia","institution_ids":["https://openalex.org/I83259278"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112642361","display_name":"Ameur Cherif","orcid":"https://orcid.org/0000-0001-7310-3842","observed_orcids":["https://orcid.org/0000-0001-7310-3842","https://orcid.org/0000-0002-0474-1530"]},"institutions":[{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Ameur Cherif","raw_affiliation_strings":["BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia","institution_ids":["https://openalex.org/I83259278"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074478053","display_name":"Mohamed Neifar","orcid":"https://orcid.org/0000-0001-6279-2769","observed_orcids":["https://orcid.org/0000-0001-6279-2769"]},"institutions":[{"id":"https://openalex.org/I142899784","display_name":"University of Sfax","ror":"https://ror.org/04d4sd432","country_code":"TN","type":"education","lineage":["https://openalex.org/I142899784"]},{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["TN"],"is_corresponding":true,"raw_author_name":"Mohamed Neifar","raw_affiliation_strings":["APVA-LR16ES20, National School of Engineers of Sfax (ENIS), University of Sfax, Sfax, Tunisia","BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"APVA-LR16ES20, National School of Engineers of Sfax (ENIS), University of Sfax, Sfax, Tunisia","institution_ids":["https://openalex.org/I142899784"]},{"raw_affiliation_string":"BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia","institution_ids":["https://openalex.org/I83259278"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5074478053"],"corresponding_institution_ids":["https://openalex.org/I142899784","https://openalex.org/I83259278"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":1.0988,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.70658509,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"10","issue":null,"first_page":"878843","last_page":"878843"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10661","display_name":"biodegradable polymer synthesis and properties","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10661","display_name":"biodegradable polymer synthesis and properties","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10324","display_name":"Microbial bioremediation and biosurfactants","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14285","display_name":"Biopolymer Synthesis and Applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polyhydroxyalkanoates","display_name":"polyhydroxyalkanoates","score":0.824999988079071},{"id":"https://openalex.org/keywords/poly-3-hydroxybutyrate-co-3-hydroxyvalerate","display_name":"poly(3-hydroxybutyrate-co-3-hydroxyvalerate)","score":0.9829999804496765},{"id":"https://openalex.org/keywords/extremophilic-bacteria","display_name":"extremophile bacteria","score":0.925000011920929},{"id":"https://openalex.org/keywords/glycerol-conversion","display_name":"glycerol conversion","score":0.6970000267028809},{"id":"https://openalex.org/keywords/cell-factories","display_name":"cell factories","score":0.6060000061988831},{"id":"https://openalex.org/keywords/phac1","display_name":"phaC1","score":0.5789999961853027},{"id":"https://openalex.org/keywords/biodegradable-polyesters","display_name":"biodegradable polyesters","score":0.7200000286102295},{"id":"https://openalex.org/keywords/culture-condition-optimization","display_name":"culture condition optimization","score":0.609000027179718}],"concepts":[{"id":"https://openalex.org/C73447357","wikidata":"https://www.wikidata.org/wiki/Q425079","display_name":"Polyhydroxyalkanoates","level":3,"score":0.9912744164466858},{"id":"https://openalex.org/C2776034031","wikidata":"https://www.wikidata.org/wiki/Q390336","display_name":"Halomonas","level":4,"score":0.6898934841156006},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.592207670211792},{"id":"https://openalex.org/C2780881558","wikidata":"https://www.wikidata.org/wiki/Q132501","display_name":"Glycerol","level":2,"score":0.5800790786743164},{"id":"https://openalex.org/C2778086801","wikidata":"https://www.wikidata.org/wiki/Q910572","display_name":"Nile red","level":3,"score":0.4932705760002136},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.47181689739227295},{"id":"https://openalex.org/C6350086","wikidata":"https://www.wikidata.org/wiki/Q6822347","display_name":"Metabolic engineering","level":3,"score":0.4233129918575287},{"id":"https://openalex.org/C553450214","wikidata":"https://www.wikidata.org/wiki/Q851162","display_name":"Biosynthesis","level":3,"score":0.41937902569770813},{"id":"https://openalex.org/C205458427","wikidata":"https://www.wikidata.org/wiki/Q206912","display_name":"Extremophile","level":4,"score":0.41685622930526733},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.37390953302383423},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31311163306236267},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3117351531982422},{"id":"https://openalex.org/C27911776","wikidata":"https://www.wikidata.org/wiki/Q834023","display_name":"Thermophile","level":3,"score":0.1187414824962616},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07931163907051086},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C42062724","wikidata":"https://www.wikidata.org/wiki/Q1209205","display_name":"16S ribosomal RNA","level":3,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fbioe.2022.878843","doi":"https://doi.org/10.3389/fbioe.2022.878843","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2022.878843","pdf_url":"https://www.frontiersin.org/articles/10.3389/fbioe.2022.878843/pdf","source":{"id":"https://openalex.org/S2595131146","display_name":"Frontiers in Bioengineering and Biotechnology","issn_l":"2296-4185","issn":["2296-4185"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioengineering and Biotechnology","raw_type":"journal-article"},{"id":"pmid:35677302","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35677302","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in bioengineering and biotechnology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9168272","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9168272/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Bioeng Biotechnol","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:f861e9fff2514cb1820aa08aad29c398","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/f861e9fff2514cb1820aa08aad29c398","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fbioe.2022.878843","doi":"https://doi.org/10.3389/fbioe.2022.878843","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2022.878843","pdf_url":"https://www.frontiersin.org/articles/10.3389/fbioe.2022.878843/pdf","source":{"id":"https://openalex.org/S2595131146","display_name":"Frontiers in Bioengineering and Biotechnology","issn_l":"2296-4185","issn":["2296-4185"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioengineering and Biotechnology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1599761223","display_name":"DevelopMent AnD application of integrated technological and management solutions FOR wasteWATER treatment and efficient reuse in agriculture tailored to the needs of Mediterranean African Countries","funder_award_id":"688320","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3248103598","display_name":null,"funder_award_id":"688320","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G4937468798","display_name":null,"funder_award_id":"H2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4281288091.pdf","grobid_xml":"https://content.openalex.org/works/W4281288091.grobid-xml"},"referenced_works_count":115,"referenced_works":["https://openalex.org/W166617030","https://openalex.org/W177702337","https://openalex.org/W1524744835","https://openalex.org/W1803102843","https://openalex.org/W1819132522","https://openalex.org/W1978420402","https://openalex.org/W1983771533","https://openalex.org/W1987690262","https://openalex.org/W1988889041","https://openalex.org/W1993319399","https://openalex.org/W1993824656","https://openalex.org/W1994877892","https://openalex.org/W1997099687","https://openalex.org/W2002717848","https://openalex.org/W2004216203","https://openalex.org/W2004548026","https://openalex.org/W2012524424","https://openalex.org/W2014870043","https://openalex.org/W2017110903","https://openalex.org/W2019886988","https://openalex.org/W2020583064","https://openalex.org/W2021169602","https://openalex.org/W2021426014","https://openalex.org/W2028277413","https://openalex.org/W2036079800","https://openalex.org/W2037252826","https://openalex.org/W2037961820","https://openalex.org/W2038610097","https://openalex.org/W2043989916","https://openalex.org/W2044916767","https://openalex.org/W2060362352","https://openalex.org/W2069269321","https://openalex.org/W2071888828","https://openalex.org/W2074835807","https://openalex.org/W2075792149","https://openalex.org/W2077606207","https://openalex.org/W2079523805","https://openalex.org/W2085411539","https://openalex.org/W2089378028","https://openalex.org/W2090118779","https://openalex.org/W2094458603","https://openalex.org/W2094692777","https://openalex.org/W2111104766","https://openalex.org/W2113393674","https://openalex.org/W2122339645","https://openalex.org/W2129957546","https://openalex.org/W2140538197","https://openalex.org/W2151676795","https://openalex.org/W2152211203","https://openalex.org/W2153971104","https://openalex.org/W2154564602","https://openalex.org/W2160571689","https://openalex.org/W2164441297","https://openalex.org/W2164780455","https://openalex.org/W2166030662","https://openalex.org/W2176833826","https://openalex.org/W2183732325","https://openalex.org/W2206972814","https://openalex.org/W2299279235","https://openalex.org/W2321745219","https://openalex.org/W2471488734","https://openalex.org/W2490160473","https://openalex.org/W2491088956","https://openalex.org/W2554587810","https://openalex.org/W2561795551","https://openalex.org/W2595391269","https://openalex.org/W2620639271","https://openalex.org/W2624367749","https://openalex.org/W2731605575","https://openalex.org/W2748980707","https://openalex.org/W2752252916","https://openalex.org/W2754093537","https://openalex.org/W2756270314","https://openalex.org/W2759807172","https://openalex.org/W2760731842","https://openalex.org/W2760818135","https://openalex.org/W2780282236","https://openalex.org/W2784454191","https://openalex.org/W2789709868","https://openalex.org/W2795591838","https://openalex.org/W2802951011","https://openalex.org/W2809232997","https://openalex.org/W2811194914","https://openalex.org/W2898810474","https://openalex.org/W2903891868","https://openalex.org/W2906660449","https://openalex.org/W2921665998","https://openalex.org/W2922086311","https://openalex.org/W2924535576","https://openalex.org/W2933193812","https://openalex.org/W2947134095","https://openalex.org/W2967088103","https://openalex.org/W2972754902","https://openalex.org/W2975083173","https://openalex.org/W2982387076","https://openalex.org/W2984301963","https://openalex.org/W3007679734","https://openalex.org/W3011721046","https://openalex.org/W3012262927","https://openalex.org/W3014409127","https://openalex.org/W3017273003","https://openalex.org/W3037316444","https://openalex.org/W3046246965","https://openalex.org/W3095843675","https://openalex.org/W3125499593","https://openalex.org/W3125865554","https://openalex.org/W3155451646","https://openalex.org/W3164141410","https://openalex.org/W3193820019","https://openalex.org/W3200674495","https://openalex.org/W3202413639","https://openalex.org/W3204258391","https://openalex.org/W4244736178","https://openalex.org/W4292872700","https://openalex.org/W6941489818"],"related_works":["https://openalex.org/W4391014323","https://openalex.org/W4399053262","https://openalex.org/W4390231036","https://openalex.org/W4417036070","https://openalex.org/W4200048211","https://openalex.org/W4381716020","https://openalex.org/W4282924563","https://openalex.org/W7222899462","https://openalex.org/W2809232997","https://openalex.org/W7033327631"],"abstract_inverted_index":{"Microbial":[0],"polyhydroxyalkanoates":[1,170,173,176],"(PHA)":[2],"are":[3,10],"biodegradable":[4],"and":[5,18,98,125,127,160,175,191,198,207],"biocompatible":[6],"bio-based":[7],"polyesters,":[8],"which":[9],"used":[11],"in":[12,33,49,151],"various":[13],"applications":[14],"including":[15,154],"packaging,":[16],"medical":[17],"coating":[19],"materials.":[20],"In":[21,214],"this":[22,225],"study,":[23],"an":[24],"extremophilic":[25,245],"hydrocarbonoclastic":[26],"bacterium,":[27],"previously":[28],"isolated":[29],"from":[30,219],"saline":[31],"sediment":[32],"the":[34,61,69,72,144,188,195,203,211,244,255],"Tunisian":[35],"desert,":[36],"has":[37],"been":[38],"investigated":[39],"for":[40,163,254],"PHA":[41,47,66,115,135,231],"production.":[42],"The":[43,140],"accumulation":[44],"of":[45,60,112,114,122,146,217,257],"intracellular":[46],"granules":[48],"Halomonas":[50],"desertis":[51,133,221,248],"G11":[52,106,222,249],"was":[53],"detected":[54],"by":[55,68],"Nile":[56],"blue":[57],"A":[58],"staining":[59],"colonies.":[62],"To":[63],"achieve":[64],"maximum":[65],"yield":[67],"strain":[70,107],"G11,":[71],"culture":[73],"conditions":[74],"were":[75],"optimized":[76,104],"through":[77,187],"response":[78],"surface":[79],"methodology":[80],"(RSM)":[81],"employing":[82],"a":[83,119,137,235,250],"Box-Behnken":[84],"Design":[85],"(BBD)":[86],"with":[87,234],"three":[88],"independent":[89],"variables,":[90],"namely,":[91],"substrate":[92],"concentration":[93],"(1\u20135%),":[94],"inoculum":[95],"size":[96],"(1\u20135%)":[97],"incubation":[99],"time":[100],"(5\u201315":[101],"days).":[102],"Under":[103],"conditions,":[105],"produced":[108],"1.5":[109],"g/L":[110],"(68%":[111],"DCW)":[113],"using":[116],"glycerol":[117,259],"as":[118],"substrate.":[120],"Application":[121],"NMR":[123],"(1H":[124],"13C)":[126],"FTIR":[128],"spectroscopies":[129],"showed":[130],"that":[131,224],"H.":[132,220,247],"accumulated":[134],"is":[136],"poly-3-hydroxybutyrate-co-3-hydroxyvalerate":[138],"(PHBV).":[139],"genome":[141],"analysis":[142,216],"revealed":[143],"presence":[145],"typical":[147],"structural":[148],"genes":[149],"involved":[150],"PHBV":[152],"metabolism":[153],"phaA,":[155],"phaB,":[156],"phaC,":[157],"phaP,":[158],"phaZ,":[159],"phaR,":[161],"coding":[162],"acetyl-CoA":[164,186],"acetyltransferase,":[165],"acetoacetyl-CoA":[166],"reductase,":[167],"class":[168],"I":[169,230],"synthases,":[171],"phasin,":[172],"depolymerase":[174],"synthesis":[177],"repressor,":[178],"respectively.":[179],"Glycerol":[180],"can":[181],"be":[182],"metabolized":[183],"to":[184,194,200,210,228,260],"1)":[185],"glycolysis":[189],"pathway":[190,206],"subsequently":[192,208],"converted":[193,209],"3HB":[196],"monomer,":[197],"2)":[199],"propionyl-CoA":[201],"via":[202],"threonine":[204],"biosynthetic":[205],"3HV":[212],"monomer.":[213],"silico":[215],"PhaC1":[218],"indicated":[223],"enzyme":[226],"belongs":[227],"Class":[229],"synthase":[232],"family":[233],"\u201clipase":[236],"box\u201d-like":[237],"sequence":[238],"(SYCVG).":[239],"All":[240],"these":[241],"characteristics":[242],"make":[243],"bacterium":[246],"promising":[251],"cell":[252],"factory":[253],"conversion":[256],"bio-renewable":[258],"high-value":[261],"PHBV.":[262]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2022-05-24T00:00:00"}
