{"id":"https://openalex.org/W4281254178","doi":"https://doi.org/10.1177/15533506221104382","title":"Light-Activated Vascular Anastomosis","display_name":"Light-Activated Vascular Anastomosis","publication_year":2022,"publication_date":"2022-05-21","ids":{"openalex":"https://openalex.org/W4281254178","doi":"https://doi.org/10.1177/15533506221104382","pmid":"https://pubmed.ncbi.nlm.nih.gov/35603581"},"language":"en","primary_location":{"id":"doi:10.1177/15533506221104382","doi":"https://doi.org/10.1177/15533506221104382","is_oa":false,"landing_page_url":"https://doi.org/10.1177/15533506221104382","pdf_url":null,"source":{"id":"https://openalex.org/S106375756","display_name":"Surgical Innovation","issn_l":"1553-3506","issn":["1553-3506","1553-3514"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgical Innovation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029301282","display_name":"Benjamin B. Scott","orcid":"https://orcid.org/0000-0002-2889-3694","observed_orcids":["https://orcid.org/0000-0002-2889-3694"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin B. Scott","raw_affiliation_strings":["Plastic Surgery Research Laboratory, Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA","Wellman Center for Photomedicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-2889-3694","affiliations":[{"raw_affiliation_string":"Plastic Surgery Research Laboratory, Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Wellman Center for Photomedicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048238441","display_name":"Mark A. Randolph","orcid":"https://orcid.org/0000-0003-0877-9832","observed_orcids":["https://orcid.org/0000-0003-0877-9832"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mark A. Randolph","raw_affiliation_strings":["Plastic Surgery Research Laboratory, Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plastic Surgery Research Laboratory, Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007869032","display_name":"Fernando Pozzi Semeghini Guastaldi","orcid":"https://orcid.org/0000-0001-8554-8849","observed_orcids":["https://orcid.org/0000-0001-8554-8849"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fernando P. S. Guastaldi","raw_affiliation_strings":["Skeletal Biology Research Center, Department of Oral and Maxillofacial Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Skeletal Biology Research Center, Department of Oral and Maxillofacial Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074424384","display_name":"Ruby C. Wu","orcid":"https://orcid.org/0000-0003-3725-5931","observed_orcids":["https://orcid.org/0000-0003-3725-5931"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ruby C. Wu","raw_affiliation_strings":["Wellman Center for Photomedicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wellman Center for Photomedicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025194131","display_name":"Robert W. Redmond","orcid":"https://orcid.org/0000-0001-8194-430X","observed_orcids":["https://orcid.org/0000-0001-8194-430X"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert W. Redmond","raw_affiliation_strings":["Wellman Center for Photomedicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wellman Center for Photomedicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5048238441"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"],"apc_list":{"value":3750,"currency":"USD","value_usd":3750},"apc_paid":null,"fwci":1.0403,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.72570014,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"30","issue":"2","first_page":"143","last_page":"149"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12906","display_name":"Surgical Sutures and Adhesives","score":0.8062000274658203,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12906","display_name":"Surgical Sutures and Adhesives","score":0.8062000274658203,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10926","display_name":"Peripheral Artery Disease Management","score":0.05180000141263008,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11554","display_name":"Vascular Procedures and Complications","score":0.03790000081062317,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vascular-anastomosis","display_name":"vascular anastomosis","score":0.9179999828338623},{"id":"https://openalex.org/keywords/saphenous-vein-interposition-graft","display_name":"saphenous vein interposition graft","score":0.8159999847412109},{"id":"https://openalex.org/keywords/femoral-artery-bypass","display_name":"femoral artery bypass","score":0.9909999966621399},{"id":"https://openalex.org/keywords/graft-patency","display_name":"graft patency","score":0.7720000147819519},{"id":"https://openalex.org/keywords/neointimal-hyperplasia","display_name":"intimal hyperplasia","score":0.6380000114440918},{"id":"https://openalex.org/keywords/thrombocyte-aggregation","display_name":"thrombocyte aggregation","score":0.6819999814033508},{"id":"https://openalex.org/keywords/vascular-stenosis","display_name":"vascular stenosis","score":0.6639999747276306},{"id":"https://openalex.org/keywords/sheep-model","display_name":"sheep model","score":0.781000018119812}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.898974597454071},{"id":"https://openalex.org/C8443397","wikidata":"https://www.wikidata.org/wiki/Q15177","display_name":"Anastomosis","level":2,"score":0.8764513731002808},{"id":"https://openalex.org/C2779723990","wikidata":"https://www.wikidata.org/wiki/Q707174","display_name":"Femoral artery","level":2,"score":0.620367169380188},{"id":"https://openalex.org/C2777327002","wikidata":"https://www.wikidata.org/wiki/Q2865760","display_name":"Fibrous joint","level":2,"score":0.5919821858406067},{"id":"https://openalex.org/C2776716733","wikidata":"https://www.wikidata.org/wiki/Q1890226","display_name":"Adventitia","level":2,"score":0.5809265375137329},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.5592211484909058},{"id":"https://openalex.org/C2779751240","wikidata":"https://www.wikidata.org/wiki/Q16909635","display_name":"Intimal hyperplasia","level":3,"score":0.5562543272972107},{"id":"https://openalex.org/C2777202286","wikidata":"https://www.wikidata.org/wiki/Q9609","display_name":"Vein","level":2,"score":0.5377142429351807},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5361412167549133},{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.5285224914550781},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.4538487493991852},{"id":"https://openalex.org/C2780017030","wikidata":"https://www.wikidata.org/wiki/Q368366","display_name":"Cuff","level":2,"score":0.4159778654575348},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.28928035497665405},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.24677523970603943},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11885172128677368},{"id":"https://openalex.org/C2992686903","wikidata":"https://www.wikidata.org/wiki/Q208453","display_name":"Smooth muscle","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000714","descriptor_name":"Anastomosis, Surgical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003251","descriptor_name":"Constriction, Pathologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014654","descriptor_name":"Vascular Patency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014656","descriptor_name":"Vascular Surgical Procedures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1177/15533506221104382","doi":"https://doi.org/10.1177/15533506221104382","is_oa":false,"landing_page_url":"https://doi.org/10.1177/15533506221104382","pdf_url":null,"source":{"id":"https://openalex.org/S106375756","display_name":"Surgical Innovation","issn_l":"1553-3506","issn":["1553-3506","1553-3514"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgical Innovation","raw_type":"journal-article"},{"id":"pmid:35603581","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35603581","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgical innovation","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307611","display_name":"Henry M. Jackson Foundation","ror":"https://ror.org/04q9tew83"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W1817123886","https://openalex.org/W1968460690","https://openalex.org/W1971747380","https://openalex.org/W1973263205","https://openalex.org/W1973823123","https://openalex.org/W1977599288","https://openalex.org/W1980250145","https://openalex.org/W1982076819","https://openalex.org/W1997904638","https://openalex.org/W1999512555","https://openalex.org/W2008620747","https://openalex.org/W2020044010","https://openalex.org/W2027888641","https://openalex.org/W2031243804","https://openalex.org/W2034064467","https://openalex.org/W2034080907","https://openalex.org/W2036246541","https://openalex.org/W2036909433","https://openalex.org/W2043005091","https://openalex.org/W2048943112","https://openalex.org/W2052658090","https://openalex.org/W2056265923","https://openalex.org/W2057873175","https://openalex.org/W2062255384","https://openalex.org/W2066899430","https://openalex.org/W2072586273","https://openalex.org/W2086268111","https://openalex.org/W2089143154","https://openalex.org/W2092007831","https://openalex.org/W2094138905","https://openalex.org/W2100342455","https://openalex.org/W2145939397","https://openalex.org/W2317235002","https://openalex.org/W2604422798","https://openalex.org/W2897299488","https://openalex.org/W2945192235","https://openalex.org/W3024669420","https://openalex.org/W3132517756","https://openalex.org/W4402733032"],"related_works":["https://openalex.org/W2604422798","https://openalex.org/W2119619483","https://openalex.org/W1980250145","https://openalex.org/W2082940772","https://openalex.org/W2016112123","https://openalex.org/W2043406253","https://openalex.org/W1963721421","https://openalex.org/W2331339361","https://openalex.org/W2082901316","https://openalex.org/W2364747111"],"abstract_inverted_index":{"Background.":[0],"There":[1],"have":[2,52],"been":[3,53],"few":[4],"advances":[5],"in":[6,20,25,87],"technique":[7,23,80],"since":[8],"vascular":[9,45,237],"anastomosis":[10,82,132,144,182,238],"was":[11,118,124,133,145,159],"performed":[12,160],"with":[13,30,55,147,208,224],"silk":[14],"suture":[15],"on":[16],"a":[17,63,78,136],"curved":[18],"needle":[19],"1902.":[21],"This":[22],"results":[24],"disruption":[26],"of":[27,35,49,66,83,91,220],"the":[28,72,142,180,200,221,225,252],"endothelium":[29,223],"exposed":[31],"intraluminal":[32,255],"suture,":[33],"both":[34],"which":[36],"may":[37],"lead":[38],"to":[39,161],"thrombocyte":[40],"aggregation,":[41],"intimal":[42],"hyperplasia,":[43],"and":[44,120,141,165,173,175,195,245],"stenosis.":[46],"A":[47],"variety":[48],"alternative":[50],"techniques":[51],"explored,":[54],"limited":[56],"success.":[57],"Photochemical":[58,229],"tissue":[59,69,230],"bonding":[60,231],"(PTB)":[61],"is":[62],"light-activated":[64],"methodology":[65],"rapidly":[67],"cross-linking":[68],"interfaces":[70],"at":[71,248],"molecular":[73],"level.":[74],"Herein,":[75],"we":[76],"describe":[77],"new":[79],"for":[81,254],"venous":[84,222],"interposition":[85,128],"graft":[86],"an":[88,127,233],"ovine":[89],"model":[90],"femoral":[92,109,116,157],"artery":[93,110,117],"bypass":[94,111,169],"utilizing":[95,112,139],"PTB.":[96],"Methods.":[97],"Polypay":[98],"specific":[99],"pathogen":[100],"free":[101],"sheep":[102],"(n":[103,189,213],"=":[104,190,214],"5;":[105],"40-45":[106],"kg)":[107],"underwent":[108],"saphenous":[113,122],"vein.":[114],"The":[115,130,186],"transected":[119],"reversed":[121],"vein":[123],"implanted":[125],"as":[126,135],"graft.":[129],"proximal":[131,181],"created":[134,146],"vein-over-artery":[137],"cuff":[138],"PTB,":[140],"distal":[143],"standard":[148],"interrupted":[149],"8-0":[150],"polypropylene":[151],"suture.":[152,256],"Four":[153],"weeks":[154],"post-index":[155],"operation,":[156],"angiogram":[158],"evaluate":[162],"patency,":[163],"tortuosity,":[164],"luminal":[166],"diameter.":[167],"All":[168,197],"grafts":[170,207],"were":[171,183,192],"harvested":[172],"longitudinal":[174],"transverse":[176],"histological":[177],"sections":[178],"from":[179],"analyzed.":[184],"Results.":[185],"PTB":[187],"anastomoses":[188],"5)":[191],"immediately":[193],"watertight":[194,236],"patent.":[196],"animals":[198],"survived":[199],"28-day":[201],"study":[202],"duration.":[203],"Angiography":[204],"revealed":[205,218],"patent":[206,247],"no":[209],"aneurysm":[210],"or":[211],"stenosis":[212],"5).":[215],"Histologic":[216],"examination":[217],"integration":[219],"arterial":[226,243],"adventitia.":[227],"Conclusion.":[228],"creates":[232],"immediate":[234],"strong,":[235],"that":[239],"can":[240],"withstand":[241],"physiologic":[242],"pressure":[244],"remains":[246],"28":[249],"days":[250],"without":[251],"need":[253]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-05-23T00:00:00"}
