{"id":"https://openalex.org/W4280628331","doi":"https://doi.org/10.15829/1560-4071-2022-4957","title":"Relationships between the activity of neurohormonal systems and intracardiac hemodynamics in patients with heart failure: focus on galectin-3","display_name":"Relationships between the activity of neurohormonal systems and intracardiac hemodynamics in patients with heart failure: focus on galectin-3","publication_year":2022,"publication_date":"2022-04-19","ids":{"openalex":"https://openalex.org/W4280628331","doi":"https://doi.org/10.15829/1560-4071-2022-4957"},"language":"en","primary_location":{"id":"doi:10.15829/1560-4071-2022-4957","doi":"https://doi.org/10.15829/1560-4071-2022-4957","is_oa":true,"landing_page_url":"https://doi.org/10.15829/1560-4071-2022-4957","pdf_url":"https://russjcardiol.elpub.ru/jour/article/download/4957/3690","source":{"id":"https://openalex.org/S89418226","display_name":"Russian Journal of Cardiology","issn_l":"1560-4071","issn":["1560-4071","2618-7620"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","norway-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4360969287","host_organization_name":"Russian Society of Cardiology","host_organization_lineage":["https://openalex.org/P4360969287"],"host_organization_lineage_names":["Russian Society of Cardiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Russian Journal of Cardiology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4280628331"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://russjcardiol.elpub.ru/jour/article/download/4957/3690","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021222813","display_name":"Valery I. Podzolkov","orcid":"https://orcid.org/0000-0002-0758-5609","observed_orcids":["https://orcid.org/0000-0002-0758-5609"]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"V. I. Podzolkov","raw_affiliation_strings":["I.M. Sechenov First Moscow State Medical University"],"raw_orcid":"https://orcid.org/0000-0002-0758-5609","affiliations":[{"raw_affiliation_string":"I.M. Sechenov First Moscow State Medical University","institution_ids":["https://openalex.org/I17877952"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068335592","display_name":"Natalia A. Dragomiretskaya","orcid":"https://orcid.org/0000-0002-6531-6255","observed_orcids":["https://orcid.org/0000-0002-6531-6255"]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"N. A. Dragomiretsksya","raw_affiliation_strings":["I.M. Sechenov First Moscow State Medical University"],"raw_orcid":"https://orcid.org/0000-0002-6531-6255","affiliations":[{"raw_affiliation_string":"I.M. Sechenov First Moscow State Medical University","institution_ids":["https://openalex.org/I17877952"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009849308","display_name":"A. V. Kazadaeva","orcid":"https://orcid.org/0000-0001-7294-6418","observed_orcids":["https://orcid.org/0000-0001-7294-6418"]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"A. V. Kazadaeva","raw_affiliation_strings":["I.M. Sechenov First Moscow State Medical University"],"raw_orcid":"https://orcid.org/0000-0001-7294-6418","affiliations":[{"raw_affiliation_string":"I.M. Sechenov First Moscow State Medical University","institution_ids":["https://openalex.org/I17877952"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069539514","display_name":"Yu. G. Beliaev","orcid":"https://orcid.org/0000-0002-0270-4111","observed_orcids":["https://orcid.org/0000-0002-0270-4111"]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Yu. G. Beliaev","raw_affiliation_strings":["I.M. Sechenov First Moscow State Medical University"],"raw_orcid":"https://orcid.org/0000-0002-0270-4111","affiliations":[{"raw_affiliation_string":"I.M. Sechenov First Moscow State Medical University","institution_ids":["https://openalex.org/I17877952"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065941011","display_name":"Anastasia V. Tolmacheva","orcid":"https://orcid.org/0000-0001-6319-4162","observed_orcids":["https://orcid.org/0000-0001-6319-4162","https://orcid.org/0000-0003-1687-4100"]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Anastasia V. Tolmacheva","raw_affiliation_strings":["I.M. Sechenov First Moscow State Medical University (Sechenov University)"],"raw_orcid":"https://orcid.org/0000-0001-6319-4162","affiliations":[{"raw_affiliation_string":"I.M. Sechenov First Moscow State Medical University (Sechenov University)","institution_ids":["https://openalex.org/I17877952"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I17877952"],"apc_list":null,"apc_paid":null,"fwci":4.8311,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.9643567,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"27","issue":"4","first_page":"4957","last_page":"4957"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13452","display_name":"GDF15 and Related Biomarkers","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.9629999995231628},{"id":"https://openalex.org/keywords/galectin-3","display_name":"galectin-3","score":0.9760000109672546},{"id":"https://openalex.org/keywords/nt-probnp","display_name":"NT-proBNP","score":0.9800000190734863},{"id":"https://openalex.org/keywords/heart-failure-with-preserved-ejection-fraction","display_name":"heart failure with preserved ejection fraction","score":0.8510000109672546},{"id":"https://openalex.org/keywords/heart-failure-with-mildly-reduced-ejection-fraction","display_name":"heart failure with mildly reduced ejection fraction","score":0.9369999766349792},{"id":"https://openalex.org/keywords/heart-failure-with-reduced-ejection-fraction","display_name":"heart failure with reduced ejection fraction","score":0.9980000257492065},{"id":"https://openalex.org/keywords/left-ventricular-ejection-fraction","display_name":"left ventricular ejection fraction","score":0.953000009059906},{"id":"https://openalex.org/keywords/intracardiac-hemodynamics","display_name":"intracardiac hemodynamics","score":0.8799999952316284},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7680000066757202},{"id":"https://openalex.org/keywords/heart-failure-phenotypes","display_name":"heart failure phenotypes","score":0.671999990940094}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9310013055801392},{"id":"https://openalex.org/C2776336362","wikidata":"https://www.wikidata.org/wiki/Q18028529","display_name":"Galectin-3","level":2,"score":0.8512598276138306},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7908436059951782},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.7736926078796387},{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.7609056234359741},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7438995838165283},{"id":"https://openalex.org/C2775915353","wikidata":"https://www.wikidata.org/wiki/Q1571529","display_name":"Natriuretic peptide","level":3,"score":0.6876332759857178},{"id":"https://openalex.org/C80093799","wikidata":"https://www.wikidata.org/wiki/Q366155","display_name":"Intracardiac injection","level":2,"score":0.5442604422569275}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.15829/1560-4071-2022-4957","doi":"https://doi.org/10.15829/1560-4071-2022-4957","is_oa":true,"landing_page_url":"https://doi.org/10.15829/1560-4071-2022-4957","pdf_url":"https://russjcardiol.elpub.ru/jour/article/download/4957/3690","source":{"id":"https://openalex.org/S89418226","display_name":"Russian Journal of Cardiology","issn_l":"1560-4071","issn":["1560-4071","2618-7620"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","norway-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4360969287","host_organization_name":"Russian Society of Cardiology","host_organization_lineage":["https://openalex.org/P4360969287"],"host_organization_lineage_names":["Russian Society of Cardiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Russian Journal of Cardiology","raw_type":"journal-article"},{"id":"doi:10.15829/29/1560-4071-2022-4957","doi":"https://doi.org/10.15829/29/1560-4071-2022-4957","is_oa":true,"landing_page_url":"https://doi.org/10.15829/29/1560-4071-2022-4957","pdf_url":null,"source":{"id":"https://openalex.org/S89418226","display_name":"Russian Journal of Cardiology","issn_l":"1560-4071","issn":["1560-4071","2618-7620"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","norway-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4360969287","host_organization_name":"Russian Society of Cardiology","host_organization_lineage":["https://openalex.org/P4360969287"],"host_organization_lineage_names":["Russian Society of Cardiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Russian Journal of Cardiology","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:dac89bb2ed724f98b98862c09e8cbb12","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/dac89bb2ed724f98b98862c09e8cbb12","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u0438\u0439 \u043a\u0430\u0440\u0434\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0436\u0443\u0440\u043d\u0430\u043b, Vol 27, Iss 4 (2022)","raw_type":"article"},{"id":"pmh:oai:oai.russjcardiol.elpub.ru:article/4957","doi":null,"is_oa":true,"landing_page_url":"https://russjcardiol.elpub.ru/jour/article/view/4957","pdf_url":null,"source":{"id":"https://openalex.org/S4306401104","display_name":"Russian Cardiology Journal (Russian Cardiology Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210119999","host_organization_name":"Russian Society of Cardiology","host_organization_lineage":["https://openalex.org/I4210119999"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Russian Journal of Cardiology; \u0422\u043e\u043c 27, \u2116 4 (2022); 4957","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.15829/1560-4071-2022-4957","doi":"https://doi.org/10.15829/1560-4071-2022-4957","is_oa":true,"landing_page_url":"https://doi.org/10.15829/1560-4071-2022-4957","pdf_url":"https://russjcardiol.elpub.ru/jour/article/download/4957/3690","source":{"id":"https://openalex.org/S89418226","display_name":"Russian Journal of Cardiology","issn_l":"1560-4071","issn":["1560-4071","2618-7620"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","norway-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4360969287","host_organization_name":"Russian Society of Cardiology","host_organization_lineage":["https://openalex.org/P4360969287"],"host_organization_lineage_names":["Russian Society of Cardiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Russian Journal of Cardiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4280628331.pdf","grobid_xml":"https://content.openalex.org/works/W4280628331.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1273218230","https://openalex.org/W2259742452","https://openalex.org/W2290517083","https://openalex.org/W2337798389","https://openalex.org/W2585416336","https://openalex.org/W2602766103","https://openalex.org/W2769708180","https://openalex.org/W2886220148","https://openalex.org/W2910662478","https://openalex.org/W3005910324","https://openalex.org/W3030519603","https://openalex.org/W3049109634","https://openalex.org/W3105832584","https://openalex.org/W3138430916","https://openalex.org/W3168393932"],"related_works":["https://openalex.org/W4229666347","https://openalex.org/W3082856683","https://openalex.org/W3007804710","https://openalex.org/W2090251527","https://openalex.org/W2585416336","https://openalex.org/W2006077331","https://openalex.org/W3029341975","https://openalex.org/W2388640430","https://openalex.org/W3049109634","https://openalex.org/W2384361456"],"abstract_inverted_index":{"The":[0],"introduction":[1],"of":[2,19,35,76,123,147,153,179,185,198,214,222],"novel":[3],"biomarkers":[4],"necessitates":[5],"their":[6],"detailed":[7],"study":[8,91],"in":[9,46,89,149,169,205,209,226],"patients":[10,62,118,170,210,227],"with":[11,48,63,69,119,134,171,211,228],"different":[12],"heart":[13],"failure":[14],"(HF)":[15],"phenotypes":[16],"as":[17,137],"part":[18],"a":[20,70,141,202],"personalized":[21],"approach":[22],"to":[23,143],"assessing":[24],"the":[25,74,90,121,145,150,176,182,219],"disease":[26],"severity":[27],"and":[28,44,52,58,78,110,164,207],"predicting":[29],"outcomes.":[30],"Aim.":[31],"To":[32],"assessthe":[33],"activity":[34,200],"following":[36],"neurohormonal":[37,199],"systems:":[38],"N-terminal":[39],"probrain":[40],"natriuretic":[41],"peptide":[42],"(NT-proBNP)":[43],"galectin-3":[45,80,124,148,163,187,208],"HF":[47],"preserved,":[49],"mildly":[50,103],"reduced":[51,53,104,111],"ejection":[54],"fraction":[55],"(EF).":[56],"Material":[57],"methods.":[59],"In":[60,117,175],"69":[61],"NYHA":[64],"class":[65],"II-IV":[66],"HF,":[67,120,212],"along":[68],"general":[71],"clinical":[72],"examination,":[73],"level":[75,122,136],"NT-proBNP":[77,135,206],"serum":[79,186],"was":[81,132,140],"determined":[82],"by":[83],"enzyme":[84],"immunoassay.":[85],"Results.":[86],"Patients":[87],"included":[88],"were":[92,189,224],"divided":[93],"into":[94],"3":[95],"groups:":[96],"preserved":[97,172],"EF":[98,105,112,167],"(HFpEF)":[99],"\u2014":[100,107,114],"23":[101],"patients,":[102,109,181],"(HFmrEF)":[106],"26":[108],"(HFrEF)":[113],"20":[115],"patients.":[116],"did":[125],"not":[126],"directly":[127],"depend":[128],"on":[129],"EF,":[130,217],"but":[131],"associated":[133],"follows:":[138],"there":[139],"tendency":[142],"increase":[144,204],"concentration":[146],"tertile":[151],"groups":[152],"NT-proBNP.":[154],"Correlation":[155],"analysis":[156],"revealed":[157],"significant":[158],"feedback":[159],"(r=-0,41,":[160],"p<0,05)":[161],"between":[162],"left":[165,215],"ventricular":[166,216],"only":[168],"systolic":[173],"function.":[174],"same":[177],"group":[178],"HFpEF":[180],"maximum":[183,220],"values":[184,221],"indices":[188],"noted,":[190],"reaching":[191],"10,5":[192],"[6,5;":[193],"14,5]":[194],"ng/ml.":[195],"Conclusion.":[196],"Analysis":[197],"demonstrated":[201],"unidirectional":[203],"regardless":[213],"while":[218],"galetin-3":[223],"observed":[225],"HFpEF.":[229]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":22},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-05-22T00:00:00"}