{"id":"https://openalex.org/W4280488233","doi":"https://doi.org/10.1038/s41467-022-30474-6","title":"A bio-functional polymer that prevents retinal scarring through modulation of NRF2 signalling pathway","display_name":"A bio-functional polymer that prevents retinal scarring through modulation of NRF2 signalling pathway","publication_year":2022,"publication_date":"2022-05-19","ids":{"openalex":"https://openalex.org/W4280488233","doi":"https://doi.org/10.1038/s41467-022-30474-6","pmid":"https://pubmed.ncbi.nlm.nih.gov/35589753","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9119969"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-022-30474-6","doi":"https://doi.org/10.1038/s41467-022-30474-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-022-30474-6","pdf_url":"https://www.nature.com/articles/s41467-022-30474-6.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41467-022-30474-6.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079633249","display_name":"Bhav Harshad Parikh","orcid":"https://orcid.org/0000-0003-3835-8887","observed_orcids":["https://orcid.org/0000-0003-3835-8887"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I75573869","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I75573869"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Bhav Harshad Parikh","raw_affiliation_strings":["Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I75573869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065844528","display_name":"Zengping Liu","orcid":"https://orcid.org/0000-0002-2578-293X","observed_orcids":["https://orcid.org/0000-0002-2578-293X"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4210116917","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4210116917"]},{"id":"https://openalex.org/I75573869","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I75573869"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Zengping Liu","raw_affiliation_strings":["Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","Singapore Eye Research Institute (SERI), Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-2578-293X","affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I75573869"]},{"raw_affiliation_string":"Singapore Eye Research Institute (SERI), Singapore, Singapore","institution_ids":["https://openalex.org/I4210116917"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053086316","display_name":"Paul Blakeley","orcid":"https://orcid.org/0000-0003-1670-0311","observed_orcids":["https://orcid.org/0000-0003-1670-0311","https://orcid.org/0000-0002-4168-0431"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Paul Blakeley","raw_affiliation_strings":["Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055307034","display_name":"Qianyu Lin","orcid":"https://orcid.org/0000-0002-7721-1370","observed_orcids":["https://orcid.org/0000-0002-7721-1370"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4210123095","display_name":"Institute of Materials Research and Engineering","ror":"https://ror.org/02sepg748","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I4210123095","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Qianyu Lin","raw_affiliation_strings":["Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I4210123095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017172380","display_name":"Malay Singh","orcid":"https://orcid.org/0000-0002-2219-8287","observed_orcids":["https://orcid.org/0000-0002-2219-8287"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4210148498","display_name":"Bioinformatics Institute","ror":"https://ror.org/044w3nw43","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I4210148498"]},{"id":"https://openalex.org/I75573869","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I75573869"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Malay Singh","raw_affiliation_strings":["Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-2219-8287","affiliations":[{"raw_affiliation_string":"Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I4210148498"]},{"raw_affiliation_string":"Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I75573869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003577095","display_name":"Jun Yi Ong","orcid":"https://orcid.org/0009-0003-8500-1802","observed_orcids":["https://orcid.org/0009-0003-8500-1802"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I75573869","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I75573869"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Jun Yi Ong","raw_affiliation_strings":["Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I75573869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085638414","display_name":"Kim Han Ho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I75573869","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I75573869"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Kim Han Ho","raw_affiliation_strings":["Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I75573869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100672403","display_name":"Joel Weijia Lai","orcid":"https://orcid.org/0000-0002-5619-2051","observed_orcids":["https://orcid.org/0000-0002-5619-2051"]},"institutions":[{"id":"https://openalex.org/I152815399","display_name":"Singapore University of Technology and Design","ror":"https://ror.org/05j6fvn87","country_code":"SG","type":"education","lineage":["https://openalex.org/I152815399"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Joel Weijia Lai","raw_affiliation_strings":["Science, Mathematics and Technology Cluster, Singapore University of Technology and Design (SUTD), Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-5619-2051","affiliations":[{"raw_affiliation_string":"Science, Mathematics and Technology Cluster, Singapore University of Technology and Design (SUTD), Singapore, Singapore","institution_ids":["https://openalex.org/I152815399"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042778047","display_name":"Hanumakumar Bogireddi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Hanumakumar Bogireddi","raw_affiliation_strings":["Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091682358","display_name":"Kim Chi Tran","orcid":"https://orcid.org/0009-0004-8898-7459","observed_orcids":["https://orcid.org/0009-0004-8898-7459"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Kim Chi Tran","raw_affiliation_strings":["Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090257334","display_name":"Jason Y. C. Lim","orcid":"https://orcid.org/0000-0002-8020-1720","observed_orcids":["https://orcid.org/0000-0002-8020-1720"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4210123095","display_name":"Institute of Materials Research and Engineering","ror":"https://ror.org/02sepg748","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I4210123095","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Jason Y. C. Lim","raw_affiliation_strings":["Department of Materials Science and Engineering, National University of Singapore, Singapore, Singapore","Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-8020-1720","affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I4210123095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100764305","display_name":"Kun Xue","orcid":"https://orcid.org/0000-0002-5433-0297","observed_orcids":["https://orcid.org/0000-0002-5433-0297"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4210123095","display_name":"Institute of Materials Research and Engineering","ror":"https://ror.org/02sepg748","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I4210123095","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Kun Xue","raw_affiliation_strings":["Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-5433-0297","affiliations":[{"raw_affiliation_string":"Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I4210123095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067921047","display_name":"Abdurrahmaan Al-Mubaarak","orcid":"https://orcid.org/0000-0001-6390-948X","observed_orcids":["https://orcid.org/0000-0001-6390-948X"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Abdurrahmaan Al-Mubaarak","raw_affiliation_strings":["Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0001-6390-948X","affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109303265","display_name":"Binxia Yang","orcid":"https://orcid.org/0000-0003-3043-8479","observed_orcids":["https://orcid.org/0000-0003-3043-8479"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I75573869","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I75573869"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Binxia Yang","raw_affiliation_strings":["Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I75573869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039653585","display_name":"R Sowmiya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I75573869","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I75573869"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Sowmiya R","raw_affiliation_strings":["Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I75573869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065897062","display_name":"Kakkad Regha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I75573869","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I75573869"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Kakkad Regha","raw_affiliation_strings":["Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I75573869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043494448","display_name":"Daniel Soo Lin Wong","orcid":"https://orcid.org/0000-0001-7425-6736","observed_orcids":["https://orcid.org/0000-0001-7425-6736"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Daniel Soo Lin Wong","raw_affiliation_strings":["Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0001-7425-6736","affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074588475","display_name":"Queenie Shu Woon Tan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I75573869","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I75573869"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Queenie Shu Woon Tan","raw_affiliation_strings":["Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I75573869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101538312","display_name":"Zhongxing Zhang","orcid":"https://orcid.org/0000-0001-5902-9690","observed_orcids":["https://orcid.org/0000-0001-5902-9690"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4210123095","display_name":"Institute of Materials Research and Engineering","ror":"https://ror.org/02sepg748","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I4210123095","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Zhongxing Zhang","raw_affiliation_strings":["Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I4210123095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008789298","display_name":"Anand Devaprasath D. Jeyasekharan","orcid":"https://orcid.org/0000-0001-9816-6137","observed_orcids":["https://orcid.org/0000-0001-9816-6137"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4405277804","display_name":"Cancer Science Institute of Singapore","ror":"https://ror.org/03yky5015","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4405277804"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Anand D. Jeyasekharan","raw_affiliation_strings":["Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0001-9816-6137","affiliations":[{"raw_affiliation_string":"Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596","https://openalex.org/I4405277804"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045929103","display_name":"Veluchamy A. Barathi","orcid":"https://orcid.org/0000-0002-6477-9784","observed_orcids":["https://orcid.org/0000-0002-6477-9784"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4210116917","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4210116917"]},{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Veluchamy Amutha Barathi","raw_affiliation_strings":["Academic Clinical Program in Ophthalmology, Duke-NUS Medical School, Singapore, Singapore","Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","Singapore Eye Research Institute (SERI), Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academic Clinical Program in Ophthalmology, Duke-NUS Medical School, Singapore, Singapore","institution_ids":["https://openalex.org/I4210126319"]},{"raw_affiliation_string":"Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Singapore Eye Research Institute (SERI), Singapore, Singapore","institution_ids":["https://openalex.org/I4210116917"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015449777","display_name":"Weimiao Yu","orcid":"https://orcid.org/0000-0001-5092-1009","observed_orcids":["https://orcid.org/0000-0001-5092-1009"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4210148498","display_name":"Bioinformatics Institute","ror":"https://ror.org/044w3nw43","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I4210148498"]},{"id":"https://openalex.org/I75573869","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I75573869"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Weimiao Yu","raw_affiliation_strings":["Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I4210148498"]},{"raw_affiliation_string":"Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I75573869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022778275","display_name":"Kang Hao Cheong","orcid":"https://orcid.org/0000-0002-4475-5451","observed_orcids":["https://orcid.org/0000-0002-4475-5451"]},"institutions":[{"id":"https://openalex.org/I152815399","display_name":"Singapore University of Technology and Design","ror":"https://ror.org/05j6fvn87","country_code":"SG","type":"education","lineage":["https://openalex.org/I152815399"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Kang Hao Cheong","raw_affiliation_strings":["Science, Mathematics and Technology Cluster, Singapore University of Technology and Design (SUTD), Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-4475-5451","affiliations":[{"raw_affiliation_string":"Science, Mathematics and Technology Cluster, Singapore University of Technology and Design (SUTD), Singapore, Singapore","institution_ids":["https://openalex.org/I152815399"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032722283","display_name":"Timothy A. Blenkinsop","orcid":"https://orcid.org/0000-0002-8095-9937","observed_orcids":["https://orcid.org/0000-0002-8095-9937"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy A. Blenkinsop","raw_affiliation_strings":["Department of Cellular, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054329378","display_name":"Walter Hunziker","orcid":"https://orcid.org/0000-0002-5265-4933","observed_orcids":["https://orcid.org/0000-0002-5265-4933","https://orcid.org/0000-0001-8570-1989"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I75573869","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I75573869"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Walter Hunziker","raw_affiliation_strings":["Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-5265-4933","affiliations":[{"raw_affiliation_string":"Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I75573869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091338725","display_name":"Lingam Gopal","orcid":"https://orcid.org/0000-0001-9130-5712","observed_orcids":["https://orcid.org/0000-0001-9130-5712"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4210116917","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4210116917"]},{"id":"https://openalex.org/I4210146690","display_name":"National University Hospital","ror":"https://ror.org/04fp9fm22","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210146690","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Gopal Lingam","raw_affiliation_strings":["Department of Ophthalmology, National University Hospital, Singapore, Singapore","Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","Singapore Eye Research Institute (SERI), Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0001-9130-5712","affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, National University Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I4210146690"]},{"raw_affiliation_string":"Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Singapore Eye Research Institute (SERI), Singapore, Singapore","institution_ids":["https://openalex.org/I4210116917"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059594060","display_name":"Xian Jun Loh","orcid":"https://orcid.org/0000-0001-8118-6502","observed_orcids":["https://orcid.org/0000-0001-8118-6502"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4210123095","display_name":"Institute of Materials Research and Engineering","ror":"https://ror.org/02sepg748","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I4210123095","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Xian Jun Loh","raw_affiliation_strings":["Department of Materials Science and Engineering, National University of Singapore, Singapore, Singapore. lohxj@imre.a-star.edu.sg","Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. lohxj@imre.a-star.edu.sg","Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0001-8118-6502","affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, National University of Singapore, Singapore, Singapore. lohxj@imre.a-star.edu.sg","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. lohxj@imre.a-star.edu.sg","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I4210123095"]},{"raw_affiliation_string":"Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I4210123095"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085381416","display_name":"Xinyi Su","orcid":"https://orcid.org/0000-0002-1480-6713","observed_orcids":["https://orcid.org/0000-0002-1480-6713"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4210116917","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4210116917"]},{"id":"https://openalex.org/I4210146690","display_name":"National University Hospital","ror":"https://ror.org/04fp9fm22","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210146690","https://openalex.org/I4210150261"]},{"id":"https://openalex.org/I75573869","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I75573869"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Xinyi Su","raw_affiliation_strings":["Department of Ophthalmology, National University Hospital, Singapore, Singapore. xysu@imcb.a-star.edu.sg","Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. xysu@imcb.a-star.edu.sg","Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. xysu@imcb.a-star.edu.sg","Singapore Eye Research Institute (SERI), Singapore, Singapore. xysu@imcb.a-star.edu.sg","Singapore Eye Research Institute (SERI), Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-1480-6713","affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, National University Hospital, Singapore, Singapore. xysu@imcb.a-star.edu.sg","institution_ids":["https://openalex.org/I4210146690"]},{"raw_affiliation_string":"Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. xysu@imcb.a-star.edu.sg","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. xysu@imcb.a-star.edu.sg","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I75573869"]},{"raw_affiliation_string":"Singapore Eye Research Institute (SERI), Singapore, Singapore. xysu@imcb.a-star.edu.sg","institution_ids":["https://openalex.org/I4210116917"]},{"raw_affiliation_string":"Singapore Eye Research Institute (SERI), Singapore, Singapore","institution_ids":["https://openalex.org/I4210116917"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5059594060","https://openalex.org/A5085381416"],"corresponding_institution_ids":["https://openalex.org/I115228651","https://openalex.org/I165932596","https://openalex.org/I4210116917","https://openalex.org/I4210123095","https://openalex.org/I4210146690","https://openalex.org/I75573869"],"apc_list":{"value":5890,"currency":"USD","value_usd":5890},"apc_paid":{"value":5890,"currency":"USD","value_usd":5890},"fwci":10.7347,"has_fulltext":true,"cited_by_count":55,"citation_normalized_percentile":{"value":0.99427493,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"13","issue":"1","first_page":"2796","last_page":"2796"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11377","display_name":"Retinal and Macular Surgery","score":0.9375,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11377","display_name":"Retinal and Macular Surgery","score":0.9375,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.02930000051856041,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12484","display_name":"Retinopathy of Prematurity Studies","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinal-scarring","display_name":"retinal scarring","score":0.9570000171661377},{"id":"https://openalex.org/keywords/proliferative-vitreoretinopathy","display_name":"proliferative vitreoretinopathy","score":0.9819999933242798},{"id":"https://openalex.org/keywords/retinal-detachment","display_name":"retinal detachment","score":0.8399999737739563},{"id":"https://openalex.org/keywords/retinal-pigment-epithelium","display_name":"retinal pigment epithelium","score":0.7639999985694885},{"id":"https://openalex.org/keywords/epithelial-mesenchymal-transition","display_name":"epithelial-mesenchymal transition","score":0.9919999837875366},{"id":"https://openalex.org/keywords/nrf2-signaling-pathway","display_name":"Nrf2 signaling","score":0.7509999871253967},{"id":"https://openalex.org/keywords/polymeric-micelles","display_name":"polymeric micelles","score":0.9919999837875366},{"id":"https://openalex.org/keywords/clathrin-mediated-endocytosis","display_name":"clathrin-mediated endocytosis","score":0.8579999804496765},{"id":"https://openalex.org/keywords/rpe-cell-proliferation","display_name":"RPE cell proliferation","score":0.7319999933242798},{"id":"https://openalex.org/keywords/blindness-prevention","display_name":"blindness prevention","score":0.6209999918937683}],"concepts":[{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.582451581954956},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4992189407348633},{"id":"https://openalex.org/C39743133","wikidata":"https://www.wikidata.org/wiki/Q3262595","display_name":"Signalling","level":2,"score":0.481723815202713},{"id":"https://openalex.org/C3018449070","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signalling pathways","level":3,"score":0.436318039894104},{"id":"https://openalex.org/C123079801","wikidata":"https://www.wikidata.org/wiki/Q750240","display_name":"Modulation (music)","level":2,"score":0.42185860872268677},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40365663170814514},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.38130325078964233},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29270410537719727},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.22730714082717896},{"id":"https://openalex.org/C107038049","wikidata":"https://www.wikidata.org/wiki/Q35986","display_name":"Aesthetics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002921","descriptor_name":"Cicatrix","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051267","descriptor_name":"NF-E2-Related Factor 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051267","descriptor_name":"NF-E2-Related Factor 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D055213","descriptor_name":"Retinal Pigment Epithelium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D058750","descriptor_name":"Epithelial-Mesenchymal Transition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1038/s41467-022-30474-6","doi":"https://doi.org/10.1038/s41467-022-30474-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-022-30474-6","pdf_url":"https://www.nature.com/articles/s41467-022-30474-6.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9119969","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9119969","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Commun","raw_type":"Text"},{"id":"pmid:35589753","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35589753","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature communications","raw_type":"Journal Article"},{"id":"pmh:oai:scholarbank.nus.edu.sg:10635/228597","doi":null,"is_oa":false,"landing_page_url":"https://scholarbank.nus.edu.sg/handle/10635/228597","pdf_url":null,"source":{"id":"https://openalex.org/S7407052290","display_name":"National University of Singapore","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Elements","raw_type":"Article"},{"id":"pmh:oai:RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-30474-6","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/s41467-022-30474-6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:29658a3e9704480d80f0623a65432050","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/29658a3e9704480d80f0623a65432050","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41467-022-30474-6","doi":"https://doi.org/10.1038/s41467-022-30474-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-022-30474-6","pdf_url":"https://www.nature.com/articles/s41467-022-30474-6.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1174553590","display_name":"Reversing Contractility in Epiretinal Membranes","funder_award_id":"R01EY029736","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G3316955499","display_name":null,"funder_award_id":"NRF-CRP21-2018-00103","funder_id":"https://openalex.org/F4320320709","funder_display_name":"National Research Foundation Singapore"},{"id":"https://openalex.org/G4535077629","display_name":null,"funder_award_id":"H20H7a0034","funder_id":"https://openalex.org/F4320320696","funder_display_name":"Agency for Science, Technology and Research"}],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320320696","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09"},{"id":"https://openalex.org/F4320320709","display_name":"National Research Foundation Singapore","ror":"https://ror.org/03cpyc314"},{"id":"https://openalex.org/F4320320760","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12"},{"id":"https://openalex.org/F4320335265","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4280488233.pdf","grobid_xml":"https://content.openalex.org/works/W4280488233.grobid-xml"},"referenced_works_count":71,"referenced_works":["https://openalex.org/W36887661","https://openalex.org/W46824281","https://openalex.org/W297012981","https://openalex.org/W1033780487","https://openalex.org/W1965814195","https://openalex.org/W1969190387","https://openalex.org/W1985037778","https://openalex.org/W1987713800","https://openalex.org/W2001093897","https://openalex.org/W2002936944","https://openalex.org/W2016382049","https://openalex.org/W2016750928","https://openalex.org/W2018784408","https://openalex.org/W2021240436","https://openalex.org/W2031490185","https://openalex.org/W2032760352","https://openalex.org/W2041747549","https://openalex.org/W2061348215","https://openalex.org/W2065790323","https://openalex.org/W2070696872","https://openalex.org/W2083008063","https://openalex.org/W2092741896","https://openalex.org/W2095431539","https://openalex.org/W2114232337","https://openalex.org/W2126387587","https://openalex.org/W2129909868","https://openalex.org/W2130410032","https://openalex.org/W2134526812","https://openalex.org/W2156661377","https://openalex.org/W2170103495","https://openalex.org/W2172260616","https://openalex.org/W2179438025","https://openalex.org/W2287795546","https://openalex.org/W2299279404","https://openalex.org/W2406733336","https://openalex.org/W2417535489","https://openalex.org/W2519598424","https://openalex.org/W2545276630","https://openalex.org/W2566910587","https://openalex.org/W2582825362","https://openalex.org/W2753995352","https://openalex.org/W2765897931","https://openalex.org/W2766345106","https://openalex.org/W2773072411","https://openalex.org/W2801988573","https://openalex.org/W2803418823","https://openalex.org/W2811501377","https://openalex.org/W2892069689","https://openalex.org/W2898415565","https://openalex.org/W2940005122","https://openalex.org/W2943255343","https://openalex.org/W2964849163","https://openalex.org/W2982228892","https://openalex.org/W2983091663","https://openalex.org/W2989639943","https://openalex.org/W2990443695","https://openalex.org/W2992120560","https://openalex.org/W3002509135","https://openalex.org/W3006987177","https://openalex.org/W3009016248","https://openalex.org/W3009476318","https://openalex.org/W3014869565","https://openalex.org/W3099862724","https://openalex.org/W3109540700","https://openalex.org/W3118489030","https://openalex.org/W3208137158","https://openalex.org/W3211813059","https://openalex.org/W4205451658","https://openalex.org/W4210757081","https://openalex.org/W6658400848","https://openalex.org/W6887828029"],"related_works":["https://openalex.org/W3154861246","https://openalex.org/W7052019825","https://openalex.org/W4406864247","https://openalex.org/W2800526675","https://openalex.org/W3093626738","https://openalex.org/W2339493091","https://openalex.org/W4309032761","https://openalex.org/W4394621598","https://openalex.org/W3164918554","https://openalex.org/W2974148597"],"abstract_inverted_index":{"One":[0],"common":[1],"cause":[2],"of":[3,13,32,45,68,78,83,89,121],"vision":[4],"loss":[5],"after":[6],"retinal":[7,33,61,137],"detachment":[8],"surgery":[9],"is":[10,24,57,72],"the":[11,119],"formation":[12],"proliferative":[14,69],"and":[15,30,93,114,131],"contractile":[16],"fibrocellular":[17],"membranes.":[18,47],"This":[19,71,116],"aberrant":[20],"wound":[21],"healing":[22],"process":[23],"mediated":[25,73],"by":[26,55],"epithelial-mesenchymal":[27],"transition":[28],"(EMT)":[29],"hyper-proliferation":[31,92],"pigment":[34],"epithelial":[35],"(RPE)":[36],"cells.":[37],"Current":[38],"treatment":[39],"relies":[40],"primarily":[41,74],"on":[42],"surgical":[43],"removal":[44],"these":[46],"Here,":[48],"we":[49],"demonstrate":[50],"that":[51],"a":[52,106,111,133],"bio-functional":[53,124],"polymer":[54,125],"itself":[56],"able":[58],"to":[59,126],"prevent":[60],"scarring":[62,138],"in":[63,105],"an":[64],"experimental":[65],"rabbit":[66],"model":[67],"vitreoretinopathy.":[70],"via":[75],"clathrin-dependent":[76],"internalisation":[77],"polymeric":[79],"micelles,":[80],"downstream":[81],"suppression":[82],"canonical":[84],"EMT":[85],"transcription":[86],"factors,":[87],"reduction":[88],"RPE":[90,128],"cell":[91],"migration.":[94],"Nuclear":[95],"factor":[96,99],"erythroid":[97],"2-related":[98],"2":[100],"signalling":[101],"pathway":[102],"was":[103],"identified":[104],"genome-wide":[107],"transcriptomic":[108],"profiling":[109],"as":[110],"key":[112],"sensor":[113],"effector.":[115],"study":[117],"highlights":[118],"potential":[120,134],"using":[122],"synthetic":[123],"modulate":[127],"cellular":[129],"behaviour":[130],"offers":[132],"therapy":[135],"for":[136],"prevention.":[139]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":24},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-05-22T00:00:00"}
