{"id":"https://openalex.org/W4255398729","doi":"https://doi.org/10.1016/s0024-3205(02)01913-6","title":"Effects of herbal components on cDNA-expressed cytochrome P450 enzyme catalytic activity","display_name":"Effects of herbal components on cDNA-expressed cytochrome P450 enzyme catalytic activity","publication_year":2002,"publication_date":"2002-08-01","ids":{"openalex":"https://openalex.org/W4255398729","doi":"https://doi.org/10.1016/s0024-3205(02)01913-6"},"language":"en","primary_location":{"id":"doi:10.1016/s0024-3205(02)01913-6","doi":"https://doi.org/10.1016/s0024-3205(02)01913-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0024-3205(02)01913-6","pdf_url":null,"source":{"id":"https://openalex.org/S175775512","display_name":"Life Sciences","issn_l":"0024-3205","issn":["0024-3205","1879-0631"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109584237","display_name":"Lihong Zou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L Zou","raw_affiliation_strings":["Department of Medical Pharmacology and Toxicology, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology and Toxicology, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056381800","display_name":"Martha R. Harkey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.R Harkey","raw_affiliation_strings":["Department of Medical Pharmacology and Toxicology, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology and Toxicology, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078036543","display_name":"Gary L. Henderson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"G.L Henderson","raw_affiliation_strings":["Department of Medical Pharmacology and Toxicology, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology and Toxicology, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5078036543"],"corresponding_institution_ids":["https://openalex.org/I84218800"],"apc_list":{"value":3810,"currency":"USD","value_usd":3810},"apc_paid":null,"fwci":11.2649,"has_fulltext":false,"cited_by_count":204,"citation_normalized_percentile":{"value":0.98842816,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"71","issue":"13","first_page":"1579","last_page":"1589"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10902","display_name":"Complementary and Alternative Medicine Studies","score":0.013100000098347664,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/herbal-products","display_name":"herbal products","score":0.796999990940094},{"id":"https://openalex.org/keywords/cytochrome-p450-inhibition","display_name":"cytochrome P450 inhibition","score":0.9380000233650208},{"id":"https://openalex.org/keywords/cyp2c19","display_name":"CYP2C19","score":0.8539999723434448},{"id":"https://openalex.org/keywords/cyp2c9","display_name":"CYP2C9","score":0.8659999966621399},{"id":"https://openalex.org/keywords/cyp2d6","display_name":"CYP2D6","score":0.8939999938011169},{"id":"https://openalex.org/keywords/cyp3a4","display_name":"CYP3A4","score":0.9079999923706055},{"id":"https://openalex.org/keywords/cyp1a2","display_name":"CYP1A2","score":0.9940000176429749},{"id":"https://openalex.org/keywords/drug-interactions","display_name":"drug interactions","score":0.6890000104904175},{"id":"https://openalex.org/keywords/ginkgo-biloba","display_name":"Ginkgo biloba","score":0.9679999947547913},{"id":"https://openalex.org/keywords/ginkgolic-acid","display_name":"ginkgolic acid","score":0.8629999756813049},{"id":"https://openalex.org/keywords/kava","display_name":"kava","score":0.9919999837875366},{"id":"https://openalex.org/keywords/hypericum-perforatum","display_name":"Hypericum perforatum","score":0.9419999718666077},{"id":"https://openalex.org/keywords/hyperforin","display_name":"hyperforin","score":0.9300000071525574},{"id":"https://openalex.org/keywords/quercetin","display_name":"quercetin","score":0.8420000076293945},{"id":"https://openalex.org/keywords/evening-primrose-oil","display_name":"evening primrose oil","score":0.8790000081062317},{"id":"https://openalex.org/keywords/allicin","display_name":"allicin","score":0.8650000095367432},{"id":"https://openalex.org/keywords/methysticin","display_name":"methysticin","score":0.6779999732971191},{"id":"https://openalex.org/keywords/dihydromethysticin","display_name":"dihydromethysticin","score":0.8429999947547913},{"id":"https://openalex.org/keywords/drug-metabolism","display_name":"drug metabolism","score":0.3499999940395355}],"concepts":[{"id":"https://openalex.org/C86745063","wikidata":"https://www.wikidata.org/wiki/Q3737406","display_name":"CYP1A2","level":4,"score":0.7332696318626404},{"id":"https://openalex.org/C2778998842","wikidata":"https://www.wikidata.org/wiki/Q43284","display_name":"Ginkgo biloba","level":2,"score":0.6895108222961426},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6870944499969482},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.6268163919448853},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.593314528465271},{"id":"https://openalex.org/C109650736","wikidata":"https://www.wikidata.org/wiki/Q424440","display_name":"CYP3A4","level":4,"score":0.5004336833953857},{"id":"https://openalex.org/C526171541","wikidata":"https://www.wikidata.org/wiki/Q407693","display_name":"Cytochrome P450","level":3,"score":0.4538132846355438},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3600633144378662},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15589720010757446}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0024-3205(02)01913-6","doi":"https://doi.org/10.1016/s0024-3205(02)01913-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0024-3205(02)01913-6","pdf_url":null,"source":{"id":"https://openalex.org/S175775512","display_name":"Life Sciences","issn_l":"0024-3205","issn":["0024-3205","1879-0631"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life Sciences","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G166751195","display_name":"Herb Drug Interactions","funder_award_id":"R01AT000636","funder_id":"https://openalex.org/F4320337593","funder_display_name":"National Center for Complementary and Integrative Health"}],"funders":[{"id":"https://openalex.org/F4320337593","display_name":"National Center for Complementary and Integrative Health","ror":"https://ror.org/00190t495"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W101448308","https://openalex.org/W150029388","https://openalex.org/W1567025276","https://openalex.org/W1918744183","https://openalex.org/W1940261063","https://openalex.org/W1964263053","https://openalex.org/W1969542481","https://openalex.org/W1969700412","https://openalex.org/W1974175694","https://openalex.org/W1985339660","https://openalex.org/W1986838867","https://openalex.org/W1987939033","https://openalex.org/W1988506721","https://openalex.org/W1989882405","https://openalex.org/W1997062399","https://openalex.org/W1998887415","https://openalex.org/W1999021046","https://openalex.org/W2008263033","https://openalex.org/W2008288621","https://openalex.org/W2009649574","https://openalex.org/W2013822904","https://openalex.org/W2015386735","https://openalex.org/W2019184564","https://openalex.org/W2023477614","https://openalex.org/W2023563192","https://openalex.org/W2024763009","https://openalex.org/W2031345014","https://openalex.org/W2051508505","https://openalex.org/W2056894910","https://openalex.org/W2060004662","https://openalex.org/W2062230123","https://openalex.org/W2063009802","https://openalex.org/W2076985436","https://openalex.org/W2088218138","https://openalex.org/W2089926385","https://openalex.org/W2096967528","https://openalex.org/W2101532045","https://openalex.org/W2102070500","https://openalex.org/W2103060442","https://openalex.org/W2107203311","https://openalex.org/W2126324290","https://openalex.org/W2127645257","https://openalex.org/W2133837027","https://openalex.org/W2149319043","https://openalex.org/W2151774137","https://openalex.org/W2171032970","https://openalex.org/W2320998834","https://openalex.org/W4299439956","https://openalex.org/W6675234537","https://openalex.org/W6675403349","https://openalex.org/W6681456016"],"related_works":["https://openalex.org/W2335600469","https://openalex.org/W1995167508","https://openalex.org/W2001515716","https://openalex.org/W2917610618","https://openalex.org/W1996093502","https://openalex.org/W2183073633","https://openalex.org/W4379142912","https://openalex.org/W7096510907","https://openalex.org/W2350007413","https://openalex.org/W1978015759"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":11}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2022-05-12T00:00:00"}