{"id":"https://openalex.org/W4253611630","doi":"https://doi.org/10.21203/rs.3.rs-72192/v1","title":"PGM5-AS1 Inhibits the Malignant Phenotype of Colon Cancer Cells by Regulating PAEP and NME1","display_name":"PGM5-AS1 Inhibits the Malignant Phenotype of Colon Cancer Cells by Regulating PAEP and NME1","publication_year":2020,"publication_date":"2020-09-08","ids":{"openalex":"https://openalex.org/W4253611630","doi":"https://doi.org/10.21203/rs.3.rs-72192/v1"},"language":"en","primary_location":{"id":"doi:10.21203/rs.3.rs-72192/v1","doi":"https://doi.org/10.21203/rs.3.rs-72192/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-72192/v1","pdf_url":"https://www.researchsquare.com/article/rs-72192/v1.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.researchsquare.com/article/rs-72192/v1.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067057979","display_name":"Bingqing Hui","orcid":"https://orcid.org/0000-0001-7354-5237","observed_orcids":["https://orcid.org/0000-0001-7354-5237"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bingqing Hui","raw_affiliation_strings":["Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital","institution_ids":["https://openalex.org/I4210152119","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100432116","display_name":"Lu Chen","orcid":"https://orcid.org/0000-0003-3235-5714","observed_orcids":["https://orcid.org/0000-0003-3235-5714"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chen Lu","raw_affiliation_strings":["Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital","institution_ids":["https://openalex.org/I4210152119","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100378656","display_name":"Jing Wang","orcid":"https://orcid.org/0000-0003-1580-1356","observed_orcids":["https://orcid.org/0000-0003-1580-1356","https://orcid.org/0009-0009-7012-5216","https://orcid.org/0000-0002-1980-539X"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Wang","raw_affiliation_strings":["Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital","Nanjing Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital","institution_ids":["https://openalex.org/I4210152119","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Nanjing Medical University","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054929346","display_name":"Yetao Xu","orcid":"https://orcid.org/0000-0002-8653-3929","observed_orcids":["https://orcid.org/0000-0002-8653-3929"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yetao Xu","raw_affiliation_strings":["Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital","institution_ids":["https://openalex.org/I4210152119","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yuchen Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuchen Yang","raw_affiliation_strings":["Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital","institution_ids":["https://openalex.org/I4210152119","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100650439","display_name":"Hao Ji","orcid":"https://orcid.org/0000-0003-1513-9884","observed_orcids":["https://orcid.org/0000-0003-1513-9884"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Ji","raw_affiliation_strings":["Shanghai Jiaotong University: Shanghai Jiao Tong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Jiaotong University: Shanghai Jiao Tong University","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100358276","display_name":"Xiaofei Li","orcid":"https://orcid.org/0000-0001-5143-9652","observed_orcids":["https://orcid.org/0000-0001-5143-9652"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaofei Li","raw_affiliation_strings":["Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital","institution_ids":["https://openalex.org/I4210152119","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014374711","display_name":"Lingyan Xu","orcid":"https://orcid.org/0000-0002-8666-5219","observed_orcids":["https://orcid.org/0000-0002-8666-5219"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lingyan Xu","raw_affiliation_strings":["Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital","institution_ids":["https://openalex.org/I4210152119","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100388793","display_name":"Jiawei Wang","orcid":"https://orcid.org/0000-0003-3885-6296","observed_orcids":["https://orcid.org/0000-0003-3885-6296"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiawei Wang","raw_affiliation_strings":["Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital","Nanjing Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital","institution_ids":["https://openalex.org/I4210152119","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Nanjing Medical University","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Keming Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138078","display_name":"Second Affiliated Hospital of Nanjing Medical University","ror":"https://ror.org/04pge2a40","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210138078"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Keming Wang","raw_affiliation_strings":["Nanjing Medical University Second Affiliated Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nanjing Medical University Second Affiliated Hospital","institution_ids":["https://openalex.org/I4210138078","https://openalex.org/I83519826"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015730356","display_name":"Yanhong Gu","orcid":"https://orcid.org/0000-0002-0379-0410","observed_orcids":["https://orcid.org/0000-0002-0379-0410","https://orcid.org/0000-0002-8708-7342","https://orcid.org/0000-0001-5033-1770"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan-Hong Gu","raw_affiliation_strings":["Department of Oncology,The First Affiliated Hospital with Nanjing Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology,The First Affiliated Hospital with Nanjing Medical University","institution_ids":["https://openalex.org/I4210152119","https://openalex.org/I83519826"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-non-coding-rna","display_name":"long non-coding RNA","score":0.9800000190734863},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.996999979019165},{"id":"https://openalex.org/keywords/oxaliplatin-resistance","display_name":"oxaliplatin resistance","score":0.9750000238418579},{"id":"https://openalex.org/keywords/acquired-drug-resistance","display_name":"acquired drug resistance","score":0.7609999775886536},{"id":"https://openalex.org/keywords/srsf3","display_name":"SRSF3","score":0.8659999966621399},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.9869999885559082},{"id":"https://openalex.org/keywords/paep","display_name":"PAEP","score":0.9070000052452087},{"id":"https://openalex.org/keywords/nm23","display_name":"nm23","score":0.9980000257492065},{"id":"https://openalex.org/keywords/gfi1b","display_name":"GFI1B","score":0.8379999995231628},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.5090000033378601},{"id":"https://openalex.org/keywords/cell-migration-and-invasion","display_name":"cell migration and invasion","score":0.7089999914169312},{"id":"https://openalex.org/keywords/mirna-sponge","display_name":"microRNA sponge","score":0.6389999985694885}],"concepts":[{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.687034010887146},{"id":"https://openalex.org/C2780962732","wikidata":"https://www.wikidata.org/wiki/Q422327","display_name":"Oxaliplatin","level":4,"score":0.6588221192359924},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6218818426132202},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.5830932259559631},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5254137516021729},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5056514739990234},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.47107377648353577},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4692404568195343},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.4690079391002655},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.4633539021015167},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4256399869918823},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.4243418574333191},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.35766172409057617},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2912617325782776},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1606680154800415}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.21203/rs.3.rs-72192/v1","doi":"https://doi.org/10.21203/rs.3.rs-72192/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-72192/v1","pdf_url":"https://www.researchsquare.com/article/rs-72192/v1.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.21203/rs.3.rs-72192/v1","doi":"https://doi.org/10.21203/rs.3.rs-72192/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-72192/v1","pdf_url":"https://www.researchsquare.com/article/rs-72192/v1.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2200463636","display_name":null,"funder_award_id":"81972278","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3240854329","display_name":null,"funder_award_id":"BRA2016517","funder_id":"https://openalex.org/F4320321605","funder_display_name":"Government of Jiangsu Province"},{"id":"https://openalex.org/G5703611615","display_name":null,"funder_award_id":"333 Project","funder_id":"https://openalex.org/F4320321605","funder_display_name":"Government of Jiangsu Province"},{"id":"https://openalex.org/G6767308739","display_name":null,"funder_award_id":"81871944","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321605","display_name":"Government of Jiangsu Province","ror":"https://ror.org/004svx814"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4253611630.pdf","grobid_xml":"https://content.openalex.org/works/W4253611630.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W1970741980","https://openalex.org/W1972011626","https://openalex.org/W1974693247","https://openalex.org/W2003553455","https://openalex.org/W2007599495","https://openalex.org/W2008342394","https://openalex.org/W2011040786","https://openalex.org/W2014210334","https://openalex.org/W2016454490","https://openalex.org/W2026657651","https://openalex.org/W2052720968","https://openalex.org/W2081300509","https://openalex.org/W2105349784","https://openalex.org/W2119938514","https://openalex.org/W2130687298","https://openalex.org/W2153906296","https://openalex.org/W2190647258","https://openalex.org/W2198153867","https://openalex.org/W2245239316","https://openalex.org/W2314476006","https://openalex.org/W2335029242","https://openalex.org/W2341291028","https://openalex.org/W2415523739","https://openalex.org/W2477394350","https://openalex.org/W2505384565","https://openalex.org/W2520001056","https://openalex.org/W2563570294","https://openalex.org/W2750877157","https://openalex.org/W2800615247","https://openalex.org/W2883250051","https://openalex.org/W2887304587","https://openalex.org/W2892305180","https://openalex.org/W2910817051","https://openalex.org/W2918407275","https://openalex.org/W2944254016","https://openalex.org/W2952083209","https://openalex.org/W2955882931","https://openalex.org/W2957928248","https://openalex.org/W2963799380","https://openalex.org/W2972820322","https://openalex.org/W2981620348","https://openalex.org/W2983864603","https://openalex.org/W3000569053","https://openalex.org/W3004937905","https://openalex.org/W3006985331","https://openalex.org/W3009963727","https://openalex.org/W4211133582","https://openalex.org/W6693826961"],"related_works":["https://openalex.org/W3198349163","https://openalex.org/W3021764415","https://openalex.org/W3154374186","https://openalex.org/W3048591641","https://openalex.org/W2980603427","https://openalex.org/W4399852350","https://openalex.org/W4391151161","https://openalex.org/W2518122545","https://openalex.org/W4226319949","https://openalex.org/W3093151974"],"abstract_inverted_index":{"Abstract":[0],"Background:":[1],"An":[2],"increasing":[3],"number":[4],"of":[5,77,92,111,126,139,153,165],"long":[6],"non-coding":[7],"RNAs":[8],"(lncRNAs)":[9],"is":[10,121],"recognized":[11],"to":[12,99,108,131,135,149],"be":[13],"associated":[14],"with":[15,147],"drug":[16],"resistance":[17,86,164],"in":[18,50,87,113],"CRC.Methods:":[19],"For":[20],"identifying":[21],"differentially":[22],"expressed":[23],"target":[24,40],"genes":[25,41],"regarding":[26],"PGM5-AS1,":[27],"RNA":[28,60],"transcriptome":[29],"sequencing":[30],"was":[31,42,66,94],"performed.":[32],"The":[33,63],"mechanism":[34],"by":[35,44,68,96,123],"which":[36],"PGM5-AS1":[37,65,81,93,112,128,143,155],"regulates":[38],"its":[39],"explored":[43],"performing":[45],"experiments":[46],"such":[47],"as":[48],"fluorescent":[49],"situ":[51],"hybridization":[52],"assay,":[53],"dual":[54],"luciferase":[55],"reporter":[56],"gene":[57],"assay":[58],"and":[59,103,118,161],"immunoprecipitation.":[61],"Results:":[62],"lncRNA":[64],"identified":[67],"analyzing":[69],"data":[70,75],"from":[71],"the":[72,137,151,157],"original":[73],"microarray":[74],"set":[76],"colon":[78,115,166],"cancer":[79,116,167],"(GSE75970).":[80],"additionally":[82],"suppressed":[83],"acquired":[84,162],"oxaliplatin":[85,163],"CRC":[88],"cells.":[89],"Malignant":[90],"phenotype":[91],"inhibited":[95],"recruiting":[97],"SRSF3":[98,130],"activate":[100,132],"alternative":[101,133],"splicing":[102,134],"being":[104],"a":[105],"sponge":[106],"specific":[107],"hsa-miR-423-5p.Conclusions:":[109],"Downregulation":[110],"oxaliplatin-resistant":[114],"tissues":[117],"cell":[119],"lines":[120],"induced":[122],"transcriptional":[124],"inhibition":[125],"GFI1B.":[127],"recruited":[129],"downregulate":[136],"expression":[138,152],"PAEP.":[140],"In":[141],"addition,":[142],"could":[144],"competitively":[145],"bind":[146],"hsa-miR-423-5p":[148],"upregulate":[150],"NME1.":[154],"inhibits":[156],"proliferation,":[158],"invasion,":[159],"migration":[160],"cells":[168],"through":[169],"these":[170],"two":[171],"pathways.":[172]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2022-05-12T00:00:00"}