{"id":"https://openalex.org/W4253594896","doi":"https://doi.org/10.1016/b978-008055232-3.61599-5","title":"Difenoxin","display_name":"Difenoxin","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W4253594896","doi":"https://doi.org/10.1016/b978-008055232-3.61599-5"},"language":"en","primary_location":{"id":"doi:10.1016/b978-008055232-3.61599-5","doi":"https://doi.org/10.1016/b978-008055232-3.61599-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-008055232-3.61599-5","pdf_url":null,"source":{"id":"https://openalex.org/S4306535192","display_name":"xPharm: The Comprehensive Pharmacology Reference","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"xPharm: The Comprehensive Pharmacology Reference","raw_type":"book-chapter"},"volume":null,"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104046994","display_name":"David B. Bylund","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David B. Bylund","raw_affiliation_strings":["University of Rochester Medical Center, Rochester, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rochester Medical Center, Rochester, USA","institution_ids":["https://openalex.org/I28792581"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018109599","display_name":"Kevin C. Bylund","orcid":"https://orcid.org/0000-0003-2484-1261","observed_orcids":["https://orcid.org/0000-0003-2484-1261"]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin Bylund","raw_affiliation_strings":["University of Rochester Medical Center, Rochester, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rochester Medical Center, Rochester, USA","institution_ids":["https://openalex.org/I28792581"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I28792581"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.79680365,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.6934000253677368,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.6934000253677368,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.09440000355243683,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11785","display_name":"Nausea and vomiting management","score":0.060100000351667404,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diphenoxylate","display_name":"diphenoxylate","score":0.9279999732971191},{"id":"https://openalex.org/keywords/antidiarrheal-agents","display_name":"antidiarrheal agents","score":0.9490000009536743},{"id":"https://openalex.org/keywords/mu-opioid-receptor-agonists","display_name":"mu-opioid receptor agonists","score":0.8840000033378601},{"id":"https://openalex.org/keywords/primary-metabolites","display_name":"primary metabolites","score":0.843999981880188},{"id":"https://openalex.org/keywords/atropine-sulfate","display_name":"atropine sulfate","score":0.7720000147819519},{"id":"https://openalex.org/keywords/drug-addiction-prevention","display_name":"drug addiction prevention","score":0.6610000133514404},{"id":"https://openalex.org/keywords/gastrointestinal-tract","display_name":"gastrointestinal tract","score":0.7279999852180481},{"id":"https://openalex.org/keywords/oral-administration","display_name":"oral administration","score":0.5139999985694885}],"concepts":[{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5656310319900513},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.5306381583213806},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4737485349178314},{"id":"https://openalex.org/C2775859210","wikidata":"https://www.wikidata.org/wiki/Q26272","display_name":"Atropine","level":2,"score":0.45183974504470825},{"id":"https://openalex.org/C2781063702","wikidata":"https://www.wikidata.org/wiki/Q427523","display_name":"Opioid","level":3,"score":0.4392312169075012},{"id":"https://openalex.org/C3017650105","wikidata":"https://www.wikidata.org/wiki/Q26272","display_name":"Atropine sulfate","level":3,"score":0.4354400932788849},{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.41307270526885986},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40145933628082275},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.23798474669456482},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.23162594437599182},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2212088406085968}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-008055232-3.61599-5","doi":"https://doi.org/10.1016/b978-008055232-3.61599-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-008055232-3.61599-5","pdf_url":null,"source":{"id":"https://openalex.org/S4306535192","display_name":"xPharm: The Comprehensive Pharmacology Reference","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"xPharm: The Comprehensive Pharmacology Reference","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/6","score":0.44999998807907104,"display_name":"Clean water and sanitation"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1993421493","https://openalex.org/W2026582960","https://openalex.org/W2030761966","https://openalex.org/W2088850045","https://openalex.org/W2122050315","https://openalex.org/W2165871503","https://openalex.org/W2287795999","https://openalex.org/W2412088472"],"related_works":["https://openalex.org/W2409424091","https://openalex.org/W2417649900","https://openalex.org/W4254279465","https://openalex.org/W2403670272","https://openalex.org/W4230367982","https://openalex.org/W2411906585","https://openalex.org/W198610249","https://openalex.org/W2030761966","https://openalex.org/W2402460563","https://openalex.org/W2297414022"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2022-05-12T00:00:00"}