{"id":"https://openalex.org/W4252431941","doi":"https://doi.org/10.1201/9780203913420.ch19","title":"The Pyruvate Dehydrogenase Multienzyme Complex","display_name":"The Pyruvate Dehydrogenase Multienzyme Complex","publication_year":2003,"publication_date":"2003-12-11","ids":{"openalex":"https://openalex.org/W4252431941","doi":"https://doi.org/10.1201/9780203913420.ch19"},"language":"en","primary_location":{"id":"doi:10.1201/9780203913420.ch19","doi":"https://doi.org/10.1201/9780203913420.ch19","is_oa":false,"landing_page_url":"https://doi.org/10.1201/9780203913420.ch19","pdf_url":null,"source":{"id":"https://openalex.org/S4210184271","display_name":"Oxidative stress and disease","issn_l":"2155-0255","issn":["2155-0255","2380-9590"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320584","host_organization_name":"CRC Press","host_organization_lineage":["https://openalex.org/P4310320584","https://openalex.org/P4310320547"],"host_organization_lineage_names":["CRC Press","Taylor & Francis"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxidative Stress and Disease","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2489296679","display_name":"Thiamine"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108288766","display_name":"Richard Nelson Perham","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard Perham","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112134175","display_name":"Jacqueline L.S. Milne","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jacqueline Milne","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5100686706","display_name":"Sriram Subramaniam","orcid":"https://orcid.org/0000-0003-4231-4115","observed_orcids":["https://orcid.org/0000-0003-4231-4115"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sriram Subramaniam","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.832,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.79742765,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12915","display_name":"Biochemical Acid Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12915","display_name":"Biochemical Acid Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pyruvate-dehydrogenase-complex","display_name":"pyruvate dehydrogenase complex","score":0.9369999766349792},{"id":"https://openalex.org/keywords/multienzyme-complex","display_name":"multienzyme complex","score":0.9359999895095825},{"id":"https://openalex.org/keywords/pyruvate-oxidation","display_name":"pyruvate oxidation","score":0.8640000224113464},{"id":"https://openalex.org/keywords/oxidative-phosphorylation","display_name":"oxidative phosphorylation","score":0.6669999957084656}],"concepts":[{"id":"https://openalex.org/C88099638","wikidata":"https://www.wikidata.org/wiki/Q412856","display_name":"Pyruvate dehydrogenase complex","level":3,"score":0.7795040011405945},{"id":"https://openalex.org/C101972281","wikidata":"https://www.wikidata.org/wiki/Q899965","display_name":"Pyruvate decarboxylation","level":4,"score":0.4191451966762543},{"id":"https://openalex.org/C190098323","wikidata":"https://www.wikidata.org/wiki/Q14912712","display_name":"Pyruvate dehydrogenase phosphatase","level":4,"score":0.4174917936325073},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39446312189102173},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3155151605606079},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.131972074508667}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1201/9780203913420.ch19","doi":"https://doi.org/10.1201/9780203913420.ch19","is_oa":false,"landing_page_url":"https://doi.org/10.1201/9780203913420.ch19","pdf_url":null,"source":{"id":"https://openalex.org/S4210184271","display_name":"Oxidative stress and disease","issn_l":"2155-0255","issn":["2155-0255","2380-9590"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320584","host_organization_name":"CRC Press","host_organization_lineage":["https://openalex.org/P4310320584","https://openalex.org/P4310320547"],"host_organization_lineage_names":["CRC Press","Taylor & Francis"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxidative Stress and Disease","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4000000059604645,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1527238249","https://openalex.org/W1530678818","https://openalex.org/W1580601386","https://openalex.org/W1825644145","https://openalex.org/W1970648377","https://openalex.org/W1977215177","https://openalex.org/W1979058406","https://openalex.org/W1986813185","https://openalex.org/W1993671723","https://openalex.org/W2000668242","https://openalex.org/W2015336205","https://openalex.org/W2016430335","https://openalex.org/W2025085729","https://openalex.org/W2040776432","https://openalex.org/W2056954970","https://openalex.org/W2064536357","https://openalex.org/W2065562263","https://openalex.org/W2068865134","https://openalex.org/W2069121977","https://openalex.org/W2079185684","https://openalex.org/W2084661994","https://openalex.org/W2087315069","https://openalex.org/W2094767163","https://openalex.org/W2095753590","https://openalex.org/W2116826071","https://openalex.org/W2120842521","https://openalex.org/W2130452502","https://openalex.org/W2148072938","https://openalex.org/W2157935454","https://openalex.org/W2168971545","https://openalex.org/W2211236154","https://openalex.org/W2418499879","https://openalex.org/W4239261932"],"related_works":["https://openalex.org/W2475383721","https://openalex.org/W253242865","https://openalex.org/W2189336582","https://openalex.org/W2488857291","https://openalex.org/W2039146754","https://openalex.org/W2494254016","https://openalex.org/W2483797962","https://openalex.org/W582042966","https://openalex.org/W2228606231","https://openalex.org/W2414705118"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2022-05-12T00:00:00"}
