{"id":"https://openalex.org/W4252018665","doi":"https://doi.org/10.1002/ange.201502379","title":"Ligand\u2010Free Copper\u2010Catalyzed Negishi Coupling of Alkyl\u2010, Aryl\u2010, and Alkynylzinc Reagents with Heteroaryl Iodides","display_name":"Ligand\u2010Free Copper\u2010Catalyzed Negishi Coupling of Alkyl\u2010, Aryl\u2010, and Alkynylzinc Reagents with Heteroaryl Iodides","publication_year":2015,"publication_date":"2015-05-28","ids":{"openalex":"https://openalex.org/W4252018665","doi":"https://doi.org/10.1002/ange.201502379"},"language":"en","primary_location":{"id":"doi:10.1002/ange.201502379","doi":"https://doi.org/10.1002/ange.201502379","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ange.201502379","pdf_url":null,"source":{"id":"https://openalex.org/S4210200754","display_name":"Angewandte Chemie","issn_l":"0044-8249","issn":["0044-8249","0932-2140","1521-3757"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Angewandte Chemie","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002616298","display_name":"Surendra Thapa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Surendra Thapa","raw_affiliation_strings":["Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131 (USA)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131 (USA)","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Arjun Kafle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arjun Kafle","raw_affiliation_strings":["Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131 (USA)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131 (USA)","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059110579","display_name":"Santosh Kumar Gurung","orcid":"https://orcid.org/0000-0003-2203-8520","observed_orcids":["https://orcid.org/0000-0003-2203-8520"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Santosh K. Gurung","raw_affiliation_strings":["Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131 (USA)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131 (USA)","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058760826","display_name":"Adam Montoya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam Montoya","raw_affiliation_strings":["Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131 (USA)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131 (USA)","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054659184","display_name":"Patrick Riedel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick Riedel","raw_affiliation_strings":["Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131 (USA)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131 (USA)","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086361985","display_name":"Ramesh Giri","orcid":"https://orcid.org/0000-0002-8993-9131","observed_orcids":["https://orcid.org/0000-0002-8993-9131"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ramesh Giri","raw_affiliation_strings":["Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131 (USA)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131 (USA)","institution_ids":["https://openalex.org/I169521973"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5086361985"],"corresponding_institution_ids":["https://openalex.org/I169521973"],"apc_list":{"value":5790,"currency":"USD","value_usd":5790},"apc_paid":null,"fwci":0.8476,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.7018317,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"127","issue":"28","first_page":"8354","last_page":"8358"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10548","display_name":"Catalytic Cross-Coupling Reactions","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10548","display_name":"Catalytic Cross-Coupling Reactions","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10354","display_name":"Catalytic C\u2013H Functionalization Methods","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12189","display_name":"Sulfur-Based Synthesis Techniques","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ligand-free-catalysis","display_name":"ligand-free catalysis","score":0.8289999961853027},{"id":"https://openalex.org/keywords/copper-catalysis","display_name":"copper catalysis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/negishi-coupling","display_name":"Negishi coupling","score":0.984000027179718},{"id":"https://openalex.org/keywords/cross-coupling","display_name":"cross-coupling","score":0.9049999713897705},{"id":"https://openalex.org/keywords/alkylzinc-reagents","display_name":"alkylzinc reagents","score":0.8809999823570251},{"id":"https://openalex.org/keywords/arylzinc-reagents","display_name":"arylzinc reagents","score":0.996999979019165},{"id":"https://openalex.org/keywords/alkynylzinc-reagents","display_name":"alkynylzinc reagents","score":0.9940000176429749},{"id":"https://openalex.org/keywords/heteroaryl-iodides","display_name":"heteroaryl iodides","score":0.996999979019165},{"id":"https://openalex.org/keywords/room-temperature-reaction","display_name":"room temperature reaction","score":0.6660000085830688}],"concepts":[{"id":"https://openalex.org/C2781076698","wikidata":"https://www.wikidata.org/wiki/Q718074","display_name":"Aryl","level":3,"score":0.8794920444488525},{"id":"https://openalex.org/C40875361","wikidata":"https://www.wikidata.org/wiki/Q2356542","display_name":"Reagent","level":2,"score":0.8558344841003418},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.8435240983963013},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8112407922744751},{"id":"https://openalex.org/C71866858","wikidata":"https://www.wikidata.org/wiki/Q902756","display_name":"Negishi coupling","level":3,"score":0.7742325067520142},{"id":"https://openalex.org/C116569031","wikidata":"https://www.wikidata.org/wiki/Q899107","display_name":"Ligand (biochemistry)","level":3,"score":0.7282657623291016},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.6930539608001709},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.5608249306678772},{"id":"https://openalex.org/C544778455","wikidata":"https://www.wikidata.org/wiki/Q753","display_name":"Copper","level":2,"score":0.514570415019989},{"id":"https://openalex.org/C48424934","wikidata":"https://www.wikidata.org/wiki/Q898912","display_name":"Coupling reaction","level":3,"score":0.47245362401008606},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.43615058064460754},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.33095037937164307},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.03495857119560242},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/ange.201502379","doi":"https://doi.org/10.1002/ange.201502379","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ange.201502379","pdf_url":null,"source":{"id":"https://openalex.org/S4210200754","display_name":"Angewandte Chemie","issn_l":"0044-8249","issn":["0044-8249","0932-2140","1521-3757"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Angewandte Chemie","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":76,"referenced_works":["https://openalex.org/W1576288888","https://openalex.org/W1964297120","https://openalex.org/W1965687448","https://openalex.org/W1968189984","https://openalex.org/W1968557236","https://openalex.org/W1974114945","https://openalex.org/W1978851116","https://openalex.org/W1982515268","https://openalex.org/W1989353253","https://openalex.org/W2001152439","https://openalex.org/W2009224104","https://openalex.org/W2011740736","https://openalex.org/W2014109638","https://openalex.org/W2020149598","https://openalex.org/W2021155443","https://openalex.org/W2027982776","https://openalex.org/W2028351186","https://openalex.org/W2033062118","https://openalex.org/W2043080681","https://openalex.org/W2043423092","https://openalex.org/W2045786154","https://openalex.org/W2060912642","https://openalex.org/W2063549773","https://openalex.org/W2069408207","https://openalex.org/W2072533747","https://openalex.org/W2078771835","https://openalex.org/W2089385547","https://openalex.org/W2090868382","https://openalex.org/W2091102942","https://openalex.org/W2095162250","https://openalex.org/W2098138588","https://openalex.org/W2098611656","https://openalex.org/W2101943021","https://openalex.org/W2105083819","https://openalex.org/W2111537995","https://openalex.org/W2113689231","https://openalex.org/W2115471369","https://openalex.org/W2117176143","https://openalex.org/W2122435016","https://openalex.org/W2127700049","https://openalex.org/W2131165784","https://openalex.org/W2131542850","https://openalex.org/W2135638091","https://openalex.org/W2140599994","https://openalex.org/W2153139582","https://openalex.org/W2153587535","https://openalex.org/W2161037600","https://openalex.org/W2164930732","https://openalex.org/W2167166532","https://openalex.org/W2172701148","https://openalex.org/W2176841615","https://openalex.org/W2287029811","https://openalex.org/W2312569616","https://openalex.org/W2312759837","https://openalex.org/W2323334357","https://openalex.org/W2327472265","https://openalex.org/W2329414490","https://openalex.org/W2497333558","https://openalex.org/W2949397228","https://openalex.org/W2950009395","https://openalex.org/W2950510356","https://openalex.org/W2950822880","https://openalex.org/W2952743149","https://openalex.org/W2952848560","https://openalex.org/W2953007704","https://openalex.org/W2953199525","https://openalex.org/W3021515054","https://openalex.org/W4231402835","https://openalex.org/W4233795835","https://openalex.org/W4234590051","https://openalex.org/W4237285257","https://openalex.org/W4240019582","https://openalex.org/W4242495195","https://openalex.org/W4250687873","https://openalex.org/W4251202056","https://openalex.org/W4255733708"],"related_works":["https://openalex.org/W2950360446","https://openalex.org/W2953191118","https://openalex.org/W2233840838","https://openalex.org/W2952286752","https://openalex.org/W2952024588","https://openalex.org/W2470065214","https://openalex.org/W2952416454","https://openalex.org/W2951761636","https://openalex.org/W2949300768","https://openalex.org/W2069408207"],"abstract_inverted_index":{"Abstract":[0],"Reported":[1],"herein":[2],"is":[3,44],"an":[4],"unprecedented":[5],"ligand\u2010free":[6],"copper\u2010catalyzed":[7],"cross\u2010coupling":[8],"of":[9,27],"alkyl\u2010,":[10],"aryl\u2010,":[11],"and":[12,30,48],"alkynylzinc":[13],"reagents":[14,33],"with":[15,34],"heteroaryl":[16,35],"iodides.":[17],"The":[18],"reaction":[19],"proceeds":[20],"at":[21],"room":[22],"temperature":[23,41],"for":[24,46],"the":[25],"coupling":[26],"primary,":[28],"secondary,":[29],"tertiary":[31],"alkylzinc":[32],"iodides":[36],"without":[37],"rearrangement.":[38],"An":[39],"elevated":[40],"(100":[42],"\u00b0C)":[43],"required":[45],"aryl\u2013heteroaryl":[47],"alkynyl\u2013heteroaryl":[49],"couplings.":[50]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2022-05-12T00:00:00"}
