{"id":"https://openalex.org/W4251165005","doi":"https://doi.org/10.20546/ijcrbp.2020.709.003","title":"Antimicrobial, anti-biofilm and anti-quorum sensing compounds from the bark of Ekebergia capensis","display_name":"Antimicrobial, anti-biofilm and anti-quorum sensing compounds from the bark of Ekebergia capensis","publication_year":2020,"publication_date":"2020-09-06","ids":{"openalex":"https://openalex.org/W4251165005","doi":"https://doi.org/10.20546/ijcrbp.2020.709.003"},"language":"en","primary_location":{"id":"doi:10.20546/ijcrbp.2020.709.003","doi":"https://doi.org/10.20546/ijcrbp.2020.709.003","is_oa":true,"landing_page_url":"https://doi.org/10.20546/ijcrbp.2020.709.003","pdf_url":"http://www.ijcrbp.com/7-9-2020/Abu F. Meka, et al.pdf","source":{"id":"https://openalex.org/S2764804930","display_name":"International Journal of Current Research in Biosciences and Plant Biology","issn_l":"2349-8072","issn":["2349-8072","2349-8080"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4322614448","host_organization_name":"Excellent Publishers","host_organization_lineage":["https://openalex.org/P4322614448"],"host_organization_lineage_names":["Excellent Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Current Research in Biosciences and Plant Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://www.ijcrbp.com/7-9-2020/Abu F. Meka, et al.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5092758454","display_name":"Abu Feyisa Meka","orcid":"https://orcid.org/0009-0006-7789-7284","observed_orcids":["https://orcid.org/0009-0006-7789-7284"]},"institutions":[{"id":"https://openalex.org/I4210124021","display_name":"Bule Hora University","ror":"https://ror.org/038n8fg68","country_code":"ET","type":"education","lineage":["https://openalex.org/I4210124021"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Abu F. Meka","raw_affiliation_strings":["Department of Biology, Natural and Computational Science College, Bule Hora University, P.O. Box 144, Bule Hora, Ethiopia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Natural and Computational Science College, Bule Hora University, P.O. Box 144, Bule Hora, Ethiopia","institution_ids":["https://openalex.org/I4210124021"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000281224","display_name":"Yadessa M. Ayana","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I865572129","display_name":"Adama Science and Technology University","ror":"https://ror.org/02ccba128","country_code":"ET","type":"education","lineage":["https://openalex.org/I865572129"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Yadessa M. Ayana","raw_affiliation_strings":["Department of Applied Biology , School of Applied Natural Science , Adama Science and Technology University , P.O. Box 1888 , Adama , Ethiopia","Department of Applied Chemistry, School of Applied Natural Science, Adama Science and Technology University, P.O. Box 1888, Adama, Ethiopia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Biology , School of Applied Natural Science , Adama Science and Technology University , P.O. Box 1888 , Adama , Ethiopia","institution_ids":["https://openalex.org/I865572129"]},{"raw_affiliation_string":"Department of Applied Chemistry, School of Applied Natural Science, Adama Science and Technology University, P.O. Box 1888, Adama, Ethiopia","institution_ids":["https://openalex.org/I865572129"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024882893","display_name":"Teshome G. Biru","orcid":"https://orcid.org/0000-0002-3858-7105","observed_orcids":["https://orcid.org/0000-0002-3858-7105"]},"institutions":[{"id":"https://openalex.org/I4210124021","display_name":"Bule Hora University","ror":"https://ror.org/038n8fg68","country_code":"ET","type":"education","lineage":["https://openalex.org/I4210124021"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Teshome G. Biru","raw_affiliation_strings":["Department of Biology, Natural and Computational Science College, Bule Hora University, P.O. Box 144, Bule Hora, Ethiopia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Natural and Computational Science College, Bule Hora University, P.O. Box 144, Bule Hora, Ethiopia","institution_ids":["https://openalex.org/I4210124021"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0714,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.28672875,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"7","issue":"9","first_page":"20","last_page":"28"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.788100004196167,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.788100004196167,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.1354999989271164,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.02500000037252903,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ekebergia-capensis","display_name":"Ekebergia capensis","score":1.0},{"id":"https://openalex.org/keywords/bark-extract","display_name":"bark extract","score":0.6669999957084656},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.8629999756813049},{"id":"https://openalex.org/keywords/antibiofilm-activity","display_name":"antibiofilm activity","score":0.9169999957084656},{"id":"https://openalex.org/keywords/anti-quorum-sensing","display_name":"anti-quorum sensing","score":0.9369999766349792},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9559999704360962},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":1.0},{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":0.8629999756813049},{"id":"https://openalex.org/keywords/biofilm-inhibition","display_name":"biofilm inhibition","score":0.8169999718666077},{"id":"https://openalex.org/keywords/swarming-motility","display_name":"swarming motility","score":0.8130000233650208},{"id":"https://openalex.org/keywords/diisobutyl-phthalate","display_name":"diisobutyl phthalate","score":0.925000011920929},{"id":"https://openalex.org/keywords/natural-product-isolation","display_name":"natural product isolation","score":0.5830000042915344},{"id":"https://openalex.org/keywords/plant-secondary-metabolites","display_name":"plant secondary metabolites","score":0.5920000076293945}],"concepts":[{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.8904148936271667},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.8628665804862976},{"id":"https://openalex.org/C118687296","wikidata":"https://www.wikidata.org/wiki/Q905754","display_name":"Quorum sensing","level":4,"score":0.8087596893310547},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.756595253944397},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.6753189563751221},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6256217360496521},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.586506187915802},{"id":"https://openalex.org/C2779858419","wikidata":"https://www.wikidata.org/wiki/Q407153","display_name":"Ethyl acetate","level":2,"score":0.5489453077316284},{"id":"https://openalex.org/C145081991","wikidata":"https://www.wikidata.org/wiki/Q2576388","display_name":"Corpus albicans","level":3,"score":0.5299433469772339},{"id":"https://openalex.org/C2780104969","wikidata":"https://www.wikidata.org/wiki/Q4774530","display_name":"Antibacterial activity","level":3,"score":0.48407498002052307},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4135361313819885},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.33546435832977295},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2561799883842468},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.20849338173866272},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07235842943191528},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.20546/ijcrbp.2020.709.003","doi":"https://doi.org/10.20546/ijcrbp.2020.709.003","is_oa":true,"landing_page_url":"https://doi.org/10.20546/ijcrbp.2020.709.003","pdf_url":"http://www.ijcrbp.com/7-9-2020/Abu F. Meka, et al.pdf","source":{"id":"https://openalex.org/S2764804930","display_name":"International Journal of Current Research in Biosciences and Plant Biology","issn_l":"2349-8072","issn":["2349-8072","2349-8080"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4322614448","host_organization_name":"Excellent Publishers","host_organization_lineage":["https://openalex.org/P4322614448"],"host_organization_lineage_names":["Excellent Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Current Research in Biosciences and Plant Biology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.20546/ijcrbp.2020.709.003","doi":"https://doi.org/10.20546/ijcrbp.2020.709.003","is_oa":true,"landing_page_url":"https://doi.org/10.20546/ijcrbp.2020.709.003","pdf_url":"http://www.ijcrbp.com/7-9-2020/Abu F. Meka, et al.pdf","source":{"id":"https://openalex.org/S2764804930","display_name":"International Journal of Current Research in Biosciences and Plant Biology","issn_l":"2349-8072","issn":["2349-8072","2349-8080"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4322614448","host_organization_name":"Excellent Publishers","host_organization_lineage":["https://openalex.org/P4322614448"],"host_organization_lineage_names":["Excellent Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Current Research in Biosciences and Plant Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4251165005.pdf","grobid_xml":"https://content.openalex.org/works/W4251165005.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W1604878006","https://openalex.org/W1942453531","https://openalex.org/W2040187818","https://openalex.org/W2044035940","https://openalex.org/W2106382522","https://openalex.org/W2159177605","https://openalex.org/W2167487133","https://openalex.org/W2527646426","https://openalex.org/W2588468474","https://openalex.org/W2792125270","https://openalex.org/W2998267399","https://openalex.org/W3011642913"],"related_works":["https://openalex.org/W2007119550","https://openalex.org/W4304944231","https://openalex.org/W2610631822","https://openalex.org/W2948372783","https://openalex.org/W4385583445","https://openalex.org/W4386120655","https://openalex.org/W2911729229","https://openalex.org/W2890020525","https://openalex.org/W7140495618","https://openalex.org/W7204757555"],"abstract_inverted_index":{"The":[0,21,87,163,187,202],"main":[1],"objective":[2],"of":[3,23,93,110,113,131,146,190],"this":[4],"study":[5],"was":[6,26,44,63,76],"to":[7,218],"isolate":[8],"bioactive":[9],"compounds":[10,100,181,192,204],"from":[11],"Ekebergia":[12],"capensis":[13,25,95],"for":[14,34,82],"antimicrobial,":[15,102,208],"anti-biofilm":[16,103],"and":[17,32,49,57,68,73,96,104,119,142,154,160,184,200,210],"anti-quorum":[18,74,105,171,211],"sensing":[19,75,106,172,212],"activity.":[20,107,213],"bark":[22],"E.":[24,94],"extracted":[27],"using":[28,65,78,195],"hexane,":[29],"ethyl":[30,90,164],"acetate":[31,91,165],"methanol":[33],"72":[35],"hours":[36],"on":[37],"maceration":[38],"at":[39,55],"room":[40],"temperature.":[41],"Antibacterial":[42],"activity":[43,51,62],"evaluated":[45,77],"against":[46,52,116,134,139,149],"Staphylococcus":[47],"aureus":[48,118],"antifungal":[50],"Candida":[53],"albicans":[54,121,156],"5":[56],"10":[58,126],"mg/mL":[59,127],"concentrations.":[60],"Anti-biofilm":[61],"tested":[64],"test":[66,71,81],"tube":[67],"swarming":[69],"motility":[70],"methods":[72,197],"flask":[79],"incubation":[80],"violacein":[83,147],"inhibition":[84,130],"production":[85,148],"methods.":[86],"results":[88],"showed":[89,129,168,206],"extract":[92,115,128],"its":[97],"two":[98,180],"isolated":[99,203],"exhibited":[101],"Inhibition":[108,145],"zones":[109],"antimicrobial":[111],"activities":[112,138],"the":[114],"S.":[117,135,143,150],"C.":[120,155],"ranged":[122],"between":[123],"4-20":[124],"mm.":[125],"biofilm":[132,224],"formation":[133],"aureus,":[136,151],"anti-swarming":[137],"P.":[140,152],"aeruginosa":[141],"aureus.":[144],"aeruginosa,":[153],"were":[157,193],"72.6%,":[158],"67.7%":[159],"69.3%":[161],"respectively.":[162],"extract,":[166],"which":[167],"antimicrobials,":[169],"anti-biofilm,":[170,209],"activities,":[173],"after":[174],"silica":[175],"gel":[176],"column":[177],"chromatography":[178],"furnished":[179],"namely;":[182],"diisobutylphtalate":[183],"Sandropin":[185],"B.":[186],"chemical":[188],"structures":[189],"these":[191],"done":[194],"spectroscopic":[196],"including":[198],"IR":[199],"NMR.":[201],"also":[205],"strong":[207],"This":[214],"could":[215],"be":[216],"useful":[217],"manage":[219],"infectious":[220],"diseases":[221],"caused":[222],"by":[223],"forming":[225],"microorganisms.":[226]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2022-05-12T00:00:00"}