{"id":"https://openalex.org/W4250200439","doi":"https://doi.org/10.3109/9781420020359.006","title":"Epidermal Growth Factor Receptor Targeted Therapy\u2014Markers of Sensitivity and Response","display_name":"Epidermal Growth Factor Receptor Targeted Therapy\u2014Markers of Sensitivity and Response","publication_year":2007,"publication_date":"2007-05-01","ids":{"openalex":"https://openalex.org/W4250200439","doi":"https://doi.org/10.3109/9781420020359.006"},"language":"en","primary_location":{"id":"doi:10.3109/9781420020359.006","doi":"https://doi.org/10.3109/9781420020359.006","is_oa":false,"landing_page_url":"https://doi.org/10.3109/9781420020359.006","pdf_url":null,"source":{"id":"https://openalex.org/S4210192933","display_name":"Translational medicine series","issn_l":"2158-0790","issn":["2158-0790","2158-0804"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Translational Medicine","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2477010046","display_name":"Lung Cancer"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054931755","display_name":"Rafa\u0142 Dziadziuszko","orcid":"https://orcid.org/0000-0001-8080-9843","observed_orcids":["https://orcid.org/0000-0001-8080-9843"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rafal Dziadziuszko","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089705899","display_name":"Barbara Szostakiewicz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Barbara Szostakiewicz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5071851332","display_name":"Fred R. Hirsch","orcid":"https://orcid.org/0000-0002-6885-1894","observed_orcids":["https://orcid.org/0000-0002-6885-1894"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fred R. Hirsch","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.61079944,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"97","last_page":"122"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.01140000019222498,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epidermal-growth-factor-receptor","display_name":"epidermal growth factor receptor","score":1.0},{"id":"https://openalex.org/keywords/anti-egfr-therapy","display_name":"anti-EGFR therapy","score":0.8429999947547913},{"id":"https://openalex.org/keywords/predictive-biomarkers","display_name":"predictive biomarkers","score":0.8769999742507935},{"id":"https://openalex.org/keywords/treatment-response","display_name":"treatment response","score":0.7039999961853027}],"concepts":[{"id":"https://openalex.org/C2779438470","wikidata":"https://www.wikidata.org/wiki/Q424401","display_name":"Epidermal growth factor receptor","level":3,"score":0.5773841142654419},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.4134235084056854},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.33833029866218567},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.32342392206192017},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3026498854160309},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22249355912208557},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.05481201410293579},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3109/9781420020359.006","doi":"https://doi.org/10.3109/9781420020359.006","is_oa":false,"landing_page_url":"https://doi.org/10.3109/9781420020359.006","pdf_url":null,"source":{"id":"https://openalex.org/S4210192933","display_name":"Translational medicine series","issn_l":"2158-0790","issn":["2158-0790","2158-0804"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Translational Medicine","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":96,"referenced_works":["https://openalex.org/W86511531","https://openalex.org/W152953340","https://openalex.org/W1619850371","https://openalex.org/W1955382134","https://openalex.org/W1967054917","https://openalex.org/W1969337484","https://openalex.org/W1970476748","https://openalex.org/W1980791428","https://openalex.org/W1985211051","https://openalex.org/W1988442083","https://openalex.org/W1989078916","https://openalex.org/W1992184657","https://openalex.org/W1992277751","https://openalex.org/W1995564515","https://openalex.org/W1997575097","https://openalex.org/W2002937040","https://openalex.org/W2003754709","https://openalex.org/W2003984225","https://openalex.org/W2016710415","https://openalex.org/W2027964476","https://openalex.org/W2030485399","https://openalex.org/W2042103473","https://openalex.org/W2042581859","https://openalex.org/W2043696829","https://openalex.org/W2044128933","https://openalex.org/W2049274590","https://openalex.org/W2052111639","https://openalex.org/W2053037610","https://openalex.org/W2062778062","https://openalex.org/W2069719383","https://openalex.org/W2076583198","https://openalex.org/W2086971982","https://openalex.org/W2093922887","https://openalex.org/W2098455835","https://openalex.org/W2100963269","https://openalex.org/W2101035251","https://openalex.org/W2101778620","https://openalex.org/W2106297623","https://openalex.org/W2107304950","https://openalex.org/W2108287705","https://openalex.org/W2110835998","https://openalex.org/W2111710483","https://openalex.org/W2114642822","https://openalex.org/W2115257917","https://openalex.org/W2118135682","https://openalex.org/W2120598067","https://openalex.org/W2120612535","https://openalex.org/W2120718661","https://openalex.org/W2120840548","https://openalex.org/W2121389354","https://openalex.org/W2122343496","https://openalex.org/W2122885616","https://openalex.org/W2125195105","https://openalex.org/W2127101185","https://openalex.org/W2132542518","https://openalex.org/W2135595269","https://openalex.org/W2136263263","https://openalex.org/W2138297714","https://openalex.org/W2138312420","https://openalex.org/W2138526447","https://openalex.org/W2138604360","https://openalex.org/W2140775102","https://openalex.org/W2142564546","https://openalex.org/W2142850084","https://openalex.org/W2143171062","https://openalex.org/W2143859186","https://openalex.org/W2146404049","https://openalex.org/W2148174696","https://openalex.org/W2148292366","https://openalex.org/W2148686475","https://openalex.org/W2149026055","https://openalex.org/W2150923784","https://openalex.org/W2153477391","https://openalex.org/W2158863975","https://openalex.org/W2160040938","https://openalex.org/W2160866033","https://openalex.org/W2161821474","https://openalex.org/W2162527007","https://openalex.org/W2162638402","https://openalex.org/W2162724777","https://openalex.org/W2165119042","https://openalex.org/W2166649051","https://openalex.org/W2167620731","https://openalex.org/W2168554121","https://openalex.org/W2168841302","https://openalex.org/W2169816570","https://openalex.org/W2229637481","https://openalex.org/W2242848604","https://openalex.org/W2244058194","https://openalex.org/W2244823046","https://openalex.org/W2268875846","https://openalex.org/W2270186974","https://openalex.org/W2307401149","https://openalex.org/W2531311781","https://openalex.org/W2590742115","https://openalex.org/W3011897760"],"related_works":["https://openalex.org/W2495924899","https://openalex.org/W4229812480","https://openalex.org/W4233665120","https://openalex.org/W2911111110","https://openalex.org/W2434146443","https://openalex.org/W2154266315","https://openalex.org/W2405262285","https://openalex.org/W2417837598","https://openalex.org/W4236797006","https://openalex.org/W2560323325"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2022-05-12T00:00:00"}