{"id":"https://openalex.org/W4249953135","doi":"https://doi.org/10.1002/047120918x.emb1549","title":"Thymidylate Synthase","display_name":"Thymidylate Synthase","publication_year":2002,"publication_date":"2002-01-15","ids":{"openalex":"https://openalex.org/W4249953135","doi":"https://doi.org/10.1002/047120918x.emb1549"},"language":"en","primary_location":{"id":"doi:10.1002/047120918x.emb1549","doi":"https://doi.org/10.1002/047120918x.emb1549","is_oa":false,"landing_page_url":"https://doi.org/10.1002/047120918x.emb1549","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Encyclopedia of Molecular Biology","raw_type":"other"},"volume":{"id":"https://openalex.org/W341601379","display_name":"Encyclopedia of Molecular Biology"},"type":"reference-entry","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113535189","display_name":"Christopher K. Mathews","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131249849","display_name":"Oregon State University","ror":"https://ror.org/00ysfqy60","country_code":"US","type":"education","lineage":["https://openalex.org/I131249849"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Christopher K. Mathews","raw_affiliation_strings":["Oregon State University, Corvallis, OR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oregon State University, Corvallis, OR","institution_ids":["https://openalex.org/I131249849"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5113535189"],"corresponding_institution_ids":["https://openalex.org/I131249849"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.8695999979972839,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.8695999979972839,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.09300000220537186,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12441","display_name":"Porphyrin Metabolism and Disorders","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thymidylate-synthase","display_name":"thymidylate synthase","score":0.9980000257492065},{"id":"https://openalex.org/keywords/thymidine-biosynthesis","display_name":"thymidine biosynthesis","score":0.7760000228881836},{"id":"https://openalex.org/keywords/dttp","display_name":"dTTP","score":0.4729999899864197},{"id":"https://openalex.org/keywords/thymidine-salvage-pathway","display_name":"thymidine salvage pathway","score":0.4399999976158142}],"concepts":[{"id":"https://openalex.org/C123321153","wikidata":"https://www.wikidata.org/wiki/Q22676802","display_name":"Thymidylate synthase","level":4,"score":0.7732080221176147},{"id":"https://openalex.org/C148863701","wikidata":"https://www.wikidata.org/wiki/Q5292","display_name":"Encyclopedia","level":2,"score":0.7039788961410522},{"id":"https://openalex.org/C2778805511","wikidata":"https://www.wikidata.org/wiki/Q1713","display_name":"Citation","level":2,"score":0.6262246370315552},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.5388062000274658},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3855079412460327},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08413195610046387},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0828867256641388},{"id":"https://openalex.org/C2780456651","wikidata":"https://www.wikidata.org/wiki/Q238512","display_name":"Fluorouracil","level":3,"score":0.0},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/047120918x.emb1549","doi":"https://doi.org/10.1002/047120918x.emb1549","is_oa":false,"landing_page_url":"https://doi.org/10.1002/047120918x.emb1549","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Encyclopedia of Molecular Biology","raw_type":"other"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1411612488","https://openalex.org/W1967146695","https://openalex.org/W1974452434","https://openalex.org/W1980253503","https://openalex.org/W1989998960","https://openalex.org/W1996874053","https://openalex.org/W1998791246","https://openalex.org/W2013060968","https://openalex.org/W2018366596","https://openalex.org/W2051056969","https://openalex.org/W2053874999","https://openalex.org/W2070345146","https://openalex.org/W2074713052","https://openalex.org/W2090659763","https://openalex.org/W2114002147","https://openalex.org/W2133523998","https://openalex.org/W2143707246","https://openalex.org/W2319839873"],"related_works":["https://openalex.org/W4300467930","https://openalex.org/W1599502643","https://openalex.org/W2409150876","https://openalex.org/W4251516262","https://openalex.org/W4235985594","https://openalex.org/W2038765375","https://openalex.org/W4249061467","https://openalex.org/W4249920541","https://openalex.org/W4250032669","https://openalex.org/W2079886067"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2022-05-12T00:00:00"}