{"id":"https://openalex.org/W4249320153","doi":"https://doi.org/10.1083/jcb.2106oia179","title":"Brain endothelial TAK1 and NEMO safeguard the neurovascular unit","display_name":"Brain endothelial TAK1 and NEMO safeguard the neurovascular unit","publication_year":2015,"publication_date":"2015-09-14","ids":{"openalex":"https://openalex.org/W4249320153","doi":"https://doi.org/10.1083/jcb.2106oia179"},"language":"en","primary_location":{"id":"doi:10.1083/jcb.2106oia179","doi":"https://doi.org/10.1083/jcb.2106oia179","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.2106oia179","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Cell Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110660383","display_name":"Dirk Andreas Ridder","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dirk A. Ridder","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066223965","display_name":"Jan Wenzel","orcid":"https://orcid.org/0000-0001-6313-2439","observed_orcids":["https://orcid.org/0000-0001-6313-2439"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jan Wenzel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Kristin M\u00fcller","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kristin M\u00fcller","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053061248","display_name":"Kathrin T\u00f6llner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathrin T\u00f6llner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054853779","display_name":"Xin\u2010Kang Tong","orcid":"https://orcid.org/0000-0002-0418-1000","observed_orcids":["https://orcid.org/0000-0002-0418-1000"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xin-Kang Tong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079999367","display_name":"Julian Christopher Assmann","orcid":"https://orcid.org/0000-0002-3750-7126","observed_orcids":["https://orcid.org/0000-0002-3750-7126"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julian Christopher Assmann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029730460","display_name":"Stijn Stroobants","orcid":"https://orcid.org/0000-0002-7838-824X","observed_orcids":["https://orcid.org/0000-0002-7838-824X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stijn Stroobants","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Tobias Weber","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tobias Weber","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067083040","display_name":"Cristina Elena Niturad","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cristina Elena Niturad","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030902623","display_name":"Lisanne Fischer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lisanne Fischer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039386850","display_name":"Beate Lembrich","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Beate Lembrich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111578984","display_name":"Hartwig Wolburg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hartwig Wolburg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077468590","display_name":"Marilyn Grand\u2019Maison","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marilyn Grand'Maison","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065035761","display_name":"Panayiota Papadopoulos","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Panayiota Papadopoulos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031189214","display_name":"\u00c9va Korpos","orcid":"https://orcid.org/0000-0002-0438-4211","observed_orcids":["https://orcid.org/0000-0002-0438-4211"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eva Korpos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019732608","display_name":"F. Truchetet","orcid":"https://orcid.org/0000-0003-0933-4448","observed_orcids":["https://orcid.org/0000-0003-0933-4448"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francois Truchetet","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057206849","display_name":"Dirk Rades","orcid":"https://orcid.org/0009-0008-2046-4968","observed_orcids":["https://orcid.org/0009-0008-2046-4968","https://orcid.org/0000-0002-3221-7541"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dirk Rades","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031719922","display_name":"Lydia M. Sorokin","orcid":"https://orcid.org/0000-0001-7704-7921","observed_orcids":["https://orcid.org/0000-0001-7704-7921"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lydia Sorokin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089219567","display_name":"Marc Schmidt\u2010Supprian","orcid":"https://orcid.org/0000-0002-8543-6166","observed_orcids":["https://orcid.org/0000-0002-8543-6166"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marc Schmidt-Supprian","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056663264","display_name":"Barry J. Bedell","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Barry Bedell","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079200229","display_name":"Manolis Pasparakis","orcid":"https://orcid.org/0000-0002-9870-0966","observed_orcids":["https://orcid.org/0000-0002-9870-0966"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Manolis Pasparakis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030761711","display_name":"Detlef Balschun","orcid":"https://orcid.org/0000-0003-0065-0188","observed_orcids":["https://orcid.org/0000-0003-0065-0188"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Detlef Balschun","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073347333","display_name":"Rudi D\u2019Hooge","orcid":"https://orcid.org/0000-0003-2243-2106","observed_orcids":["https://orcid.org/0000-0003-2243-2106"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rudi D'Hooge","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010235451","display_name":"Wolfgang L\u00f6scher","orcid":"https://orcid.org/0000-0002-9648-8973","observed_orcids":["https://orcid.org/0000-0002-9648-8973"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wolfgang L\u00f6scher","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063552156","display_name":"\u00c9dith Hamel","orcid":"https://orcid.org/0000-0001-5223-7315","observed_orcids":["https://orcid.org/0000-0001-5223-7315"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Edith Hamel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5009423317","display_name":"Markus Schwaninger","orcid":"https://orcid.org/0000-0002-4510-9718","observed_orcids":["https://orcid.org/0000-0002-4510-9718"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Markus Schwaninger","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1638,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.58248881,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"210","issue":"6","first_page":"2106OIA179","last_page":"2106OIA179"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tak1","display_name":"TAK1","score":0.9860000014305115},{"id":"https://openalex.org/keywords/nemo","display_name":"NEMO","score":0.9959999918937683},{"id":"https://openalex.org/keywords/ikkepsilon","display_name":"IKK\u03b5","score":0.5230000019073486},{"id":"https://openalex.org/keywords/ikkbeta","display_name":"IKK\u03b2","score":0.6069999933242798},{"id":"https://openalex.org/keywords/brain-endothelial-cells","display_name":"brain endothelial cells","score":0.7070000171661377},{"id":"https://openalex.org/keywords/neurovascular-unit","display_name":"neurovascular unit","score":0.984000027179718},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.6610000133514404},{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.6380000114440918},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.6570000052452087}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8394820094108582},{"id":"https://openalex.org/C105572291","wikidata":"https://www.wikidata.org/wiki/Q7002775","display_name":"Neurovascular bundle","level":2,"score":0.757610023021698},{"id":"https://openalex.org/C2780771206","wikidata":"https://www.wikidata.org/wiki/Q3271761","display_name":"Safeguard","level":2,"score":0.520317554473877},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4030101001262665},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.2684189975261688},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1083/jcb.2106oia179","doi":"https://doi.org/10.1083/jcb.2106oia179","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.2106oia179","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Cell Biology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W1849625350"],"related_works":["https://openalex.org/W2556878306","https://openalex.org/W3123579094","https://openalex.org/W4244169038","https://openalex.org/W2575150378","https://openalex.org/W2737648160","https://openalex.org/W2995869876","https://openalex.org/W3131285343","https://openalex.org/W2234029817","https://openalex.org/W4285155537","https://openalex.org/W4256442967"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-05-12T00:00:00"}