{"id":"https://openalex.org/W4249011697","doi":"https://doi.org/10.1055/s-0034-1382482","title":"New bioactive lupane triterpene coumaroyl esters isolated from Buxus cochinchinensis","display_name":"New bioactive lupane triterpene coumaroyl esters isolated from Buxus cochinchinensis","publication_year":2014,"publication_date":"2014-07-14","ids":{"openalex":"https://openalex.org/W4249011697","doi":"https://doi.org/10.1055/s-0034-1382482"},"language":"en","primary_location":{"id":"doi:10.1055/s-0034-1382482","doi":"https://doi.org/10.1055/s-0034-1382482","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0034-1382482","pdf_url":null,"source":{"id":"https://openalex.org/S39653451","display_name":"Planta Medica","issn_l":"0032-0943","issn":["0032-0943","1439-0221"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Planta Medica","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"L Pan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Pan","raw_affiliation_strings":["Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110504033","display_name":"Ulyana Mu\u00f1oz Acu\u00f1a","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"U Mu\u00f1oz Acu\u00f1a","raw_affiliation_strings":["Division of Pharmacy Practice and Administration, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pharmacy Practice and Administration, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110332740","display_name":"HB Chai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Chai","raw_affiliation_strings":["Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110463122","display_name":"TN Ninh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405280772","display_name":"Vi\u1ec7n Sinh th\u00e1i v\u00e0 T\u00e0i nguy\u00ean sinh v\u1eadt","ror":"https://ror.org/03dth0f39","country_code":"VN","type":"facility","lineage":["https://openalex.org/I4405276878","https://openalex.org/I4405280772","https://openalex.org/I70349855"]},{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"TN Ninh","raw_affiliation_strings":["Institute of Ecology and Biological Resources, Vietnam Academy of Science and Technology, Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Ecology and Biological Resources, Vietnam Academy of Science and Technology, Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam","institution_ids":["https://openalex.org/I4405280772","https://openalex.org/I70349855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153168028","display_name":"HLR Rakotondraibe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"HLR Rakotondraibe","raw_affiliation_strings":["Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085673613","display_name":"Esperanza J. Carcache de Blanco","orcid":"https://orcid.org/0000-0002-9519-3292","observed_orcids":["https://orcid.org/0000-0002-9519-3292"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"EJ Carcache de Blanco","raw_affiliation_strings":["Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy","Division of Pharmacy Practice and Administration, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy","institution_ids":[]},{"raw_affiliation_string":"Division of Pharmacy Practice and Administration, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108387280","display_name":"Djaja Doel Soejarto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802093357","display_name":"Field Museum of Natural History","ror":"https://ror.org/00mh9zx15","country_code":"US","type":"archive","lineage":["https://openalex.org/I2802093357"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"DD Soejarto","raw_affiliation_strings":["Department of Botany, Field Museum of Natural History, 1400 S. Lake Shore Drive, Chicago, IL 60605, USA","Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Botany, Field Museum of Natural History, 1400 S. Lake Shore Drive, Chicago, IL 60605, USA","institution_ids":["https://openalex.org/I2802093357"]},{"raw_affiliation_string":"Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013002429","display_name":"Alan Douglas Kinghorn","orcid":"https://orcid.org/0000-0002-6647-8707","observed_orcids":["https://orcid.org/0000-0002-6647-8707"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"AD Kinghorn","raw_affiliation_strings":["Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1366,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.53633504,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"80","issue":"10","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12215","display_name":"Phytochemical Studies and Bioactivities","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12685","display_name":"Phytochemical compounds biological activities","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lupane-triterpenoids","display_name":"lupane triterpenoids","score":0.9139999747276306},{"id":"https://openalex.org/keywords/buxaceae","display_name":"Buxaceae","score":0.8669999837875366},{"id":"https://openalex.org/keywords/natural-product-isolation","display_name":"natural product isolation","score":0.9330000281333923},{"id":"https://openalex.org/keywords/structure-elucidation","display_name":"structure elucidation","score":0.7829999923706055},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9100000262260437},{"id":"https://openalex.org/keywords/ht-29-cells","display_name":"HT-29 cells","score":0.871999979019165},{"id":"https://openalex.org/keywords/antimalarial-activity","display_name":"antimalarial activity","score":0.9789999723434448},{"id":"https://openalex.org/keywords/antifungal-activity","display_name":"antifungal activity","score":0.9649999737739563},{"id":"https://openalex.org/keywords/bioactive-compounds","display_name":"bioactive compounds","score":0.7919999957084656}],"concepts":[{"id":"https://openalex.org/C2780527577","wikidata":"https://www.wikidata.org/wiki/Q2915788","display_name":"Triterpene","level":3,"score":0.9054439067840576},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.6033851504325867},{"id":"https://openalex.org/C44937612","wikidata":"https://www.wikidata.org/wiki/Q212364","display_name":"Terpene","level":2,"score":0.5693455338478088},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.49671751260757446},{"id":"https://openalex.org/C2994372470","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell lines","level":4,"score":0.44561222195625305},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3577844500541687},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.33236417174339294},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.3265482187271118},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15668052434921265},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.15396487712860107},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.1374097466468811},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-0034-1382482","doi":"https://doi.org/10.1055/s-0034-1382482","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0034-1382482","pdf_url":null,"source":{"id":"https://openalex.org/S39653451","display_name":"Planta Medica","issn_l":"0032-0943","issn":["0032-0943","1439-0221"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Planta Medica","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4396665083","https://openalex.org/W4392737682","https://openalex.org/W2010266572","https://openalex.org/W2128275684","https://openalex.org/W1991916721","https://openalex.org/W1883819202","https://openalex.org/W1974363507","https://openalex.org/W4413915440","https://openalex.org/W4389855565","https://openalex.org/W3207089475"],"abstract_inverted_index":{"Five":[0],"new":[1,46],"lupane":[2],"triterpene":[3],"coumaroyl":[4],"esters":[5],"(1":[6,48],"\u2013":[7,49],"5)":[8,50],"were":[9,51,81],"isolated":[10],"from":[11],"a":[12,18],"CHCl":[13],"3":[14],"-soluble":[15],"partition":[16],"of":[17,21,44,56],"methanol":[19],"extract":[20],"Buxus":[22],"cochinchinensis":[23],"Pierre":[24],"ex":[25],"Gagnep.":[26],"(Buxaceae)":[27],"collected":[28],"in":[29,75,86],"South":[30],"Vietnam.":[31],"Isolation":[32],"work":[33],"was":[34],"monitored":[35],"using":[36],"human":[37],"colon":[38],"cancer":[39],"cells":[40,67],"(HT-29).":[41],"The":[42],"structures":[43],"the":[45,54,63],"compounds":[47],"determined":[52],"on":[53],"basis":[55],"spectroscopic":[57],"data":[58],"interpretation.":[59],"In":[60],"addition":[61],"to":[62],"cytotoxicities":[64],"against":[65],"HT-29":[66],"and":[68,89],"NF-":[69],"\u03ba":[70],"B":[71],"(p65)":[72],"inhibitory":[73],"activities":[74],"an":[76],"ELISA":[77],"assay,":[78],"all":[79],"isolates":[80],"also":[82],"evaluated":[83],"for":[84],"their":[85],"vitro":[87],"antimalarial":[88],"antifungal":[90],"activities.":[91]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2022-05-12T00:00:00"}