{"id":"https://openalex.org/W4247814432","doi":"https://doi.org/10.1111/j.1432-1033.1972.tb01876.x","title":"The Covalent Structure of Sheep-Heart Myoglobin","display_name":"The Covalent Structure of Sheep-Heart Myoglobin","publication_year":1972,"publication_date":"1972-06-01","ids":{"openalex":"https://openalex.org/W4247814432","doi":"https://doi.org/10.1111/j.1432-1033.1972.tb01876.x","pmid":"https://pubmed.ncbi.nlm.nih.gov/5065743"},"language":"en","primary_location":{"id":"doi:10.1111/j.1432-1033.1972.tb01876.x","doi":"https://doi.org/10.1111/j.1432-1033.1972.tb01876.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1432-1033.1972.tb01876.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210214924","display_name":"European Journal of Biochemistry","issn_l":"0014-2956","issn":["0014-2956","0945-5795","1432-1033"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013246721","display_name":"Kia\u2010Ki Han","orcid":"https://orcid.org/0009-0001-4980-4259","observed_orcids":["https://orcid.org/0009-0001-4980-4259"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kia-Ki HAN","raw_affiliation_strings":["Laboratoire de Chimie Biologique Faculte\u0301 de Me\u0301decine et de Pharmacie Place de Verdun, F-59 Lille, France","Laboratoire de Chimie Biologique Facult\u00e9 de M\u00e9decine et de Pharmacie Place de Verdun, F-59 Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Chimie Biologique Faculte\u0301 de Me\u0301decine et de Pharmacie Place de Verdun, F-59 Lille, France","institution_ids":[]},{"raw_affiliation_string":"Laboratoire de Chimie Biologique Facult\u00e9 de M\u00e9decine et de Pharmacie Place de Verdun, F-59 Lille, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026912294","display_name":"Daniel T\u00e9taert","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel TETAERT","raw_affiliation_strings":["Laboratoire de Chimie Biologique Faculte\u0301 de Me\u0301decine et de Pharmacie Place de Verdun, F-59 Lille, France","Laboratoire de Chimie Biologique Facult\u00e9 de M\u00e9decine et de Pharmacie Place de Verdun, F-59 Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Chimie Biologique Faculte\u0301 de Me\u0301decine et de Pharmacie Place de Verdun, F-59 Lille, France","institution_ids":[]},{"raw_affiliation_string":"Laboratoire de Chimie Biologique Facult\u00e9 de M\u00e9decine et de Pharmacie Place de Verdun, F-59 Lille, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037723267","display_name":"Yves Moschetto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yves MOSCHETTO","raw_affiliation_strings":["Laboratoire de Chimie Biologique Faculte\u0301 de Me\u0301decine et de Pharmacie Place de Verdun, F-59 Lille, France","Laboratoire de Chimie Biologique Facult\u00e9 de M\u00e9decine et de Pharmacie Place de Verdun, F-59 Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Chimie Biologique Faculte\u0301 de Me\u0301decine et de Pharmacie Place de Verdun, F-59 Lille, France","institution_ids":[]},{"raw_affiliation_string":"Laboratoire de Chimie Biologique Facult\u00e9 de M\u00e9decine et de Pharmacie Place de Verdun, F-59 Lille, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110810084","display_name":"M Dautrevaux","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michel DAUTREVAUX","raw_affiliation_strings":["Laboratoire de Chimie Biologique Faculte\u0301 de Me\u0301decine et de Pharmacie Place de Verdun, F-59 Lille, France","Laboratoire de Chimie Biologique Facult\u00e9 de M\u00e9decine et de Pharmacie Place de Verdun, F-59 Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Chimie Biologique Faculte\u0301 de Me\u0301decine et de Pharmacie Place de Verdun, F-59 Lille, France","institution_ids":[]},{"raw_affiliation_string":"Laboratoire de Chimie Biologique Facult\u00e9 de M\u00e9decine et de Pharmacie Place de Verdun, F-59 Lille, France","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045903011","display_name":"Charles Kopeyan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Charles KOPEYAN","raw_affiliation_strings":["Laboratoire de Biochimie Biologique, Faculte\u0301 de Me\u0301decine 27 Boulevard Jean-Moulin, F-13 Marseille 5, France","Laboratoire de Biochimie Biologique, Facult\u00e9 de M\u00e9decine 27 Boulevard Jean-Moulin, F-13 Marseille 5, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biochimie Biologique, Faculte\u0301 de Me\u0301decine 27 Boulevard Jean-Moulin, F-13 Marseille 5, France","institution_ids":[]},{"raw_affiliation_string":"Laboratoire de Biochimie Biologique, Facult\u00e9 de M\u00e9decine 27 Boulevard Jean-Moulin, F-13 Marseille 5, France","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.8095,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.93516062,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"27","issue":"3","first_page":"585","last_page":"592"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.012600000016391277,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amino-acid-sequence","display_name":"amino acid sequence","score":0.828000009059906},{"id":"https://openalex.org/keywords/cyanogen-bromide-cleavage","display_name":"cyanogen bromide cleavage","score":0.871999979019165},{"id":"https://openalex.org/keywords/n-terminal-sequence","display_name":"N-terminal sequence","score":0.7820000052452087},{"id":"https://openalex.org/keywords/protein-sequencing","display_name":"protein sequencing","score":0.4749999940395355},{"id":"https://openalex.org/keywords/codon-substitution","display_name":"codon substitution","score":0.5080000162124634},{"id":"https://openalex.org/keywords/covalent-structure","display_name":"covalent structure","score":0.7120000123977661}],"concepts":[{"id":"https://openalex.org/C2777093645","wikidata":"https://www.wikidata.org/wiki/Q420258","display_name":"Cyanogen bromide","level":4,"score":0.9760552048683167},{"id":"https://openalex.org/C2778063876","wikidata":"https://www.wikidata.org/wiki/Q192642","display_name":"Myoglobin","level":2,"score":0.9148159027099609},{"id":"https://openalex.org/C125996951","wikidata":"https://www.wikidata.org/wiki/Q412234","display_name":"Globin","level":3,"score":0.7414605617523193},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6835182905197144},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.5256537199020386},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.5251200795173645},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.4977305233478546},{"id":"https://openalex.org/C87933860","wikidata":"https://www.wikidata.org/wiki/Q898506","display_name":"Edman degradation","level":4,"score":0.49329203367233276},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.45971134305000305},{"id":"https://openalex.org/C193363816","wikidata":"https://www.wikidata.org/wiki/Q1617865","display_name":"Size-exclusion chromatography","level":3,"score":0.44288522005081177},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.43914008140563965},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.43570056557655334},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.11363190412521362},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001322","descriptor_name":"Autoanalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002850","descriptor_name":"Chromatography, Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002852","descriptor_name":"Chromatography, Ion Exchange","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002918","descriptor_name":"Chymotrypsin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003488","descriptor_name":"Cyanogen Bromide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004590","descriptor_name":"Electrophoresis, Paper","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005815","descriptor_name":"Genetic Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009211","descriptor_name":"Myoglobin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014357","descriptor_name":"Trypsin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1432-1033.1972.tb01876.x","doi":"https://doi.org/10.1111/j.1432-1033.1972.tb01876.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1432-1033.1972.tb01876.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210214924","display_name":"European Journal of Biochemistry","issn_l":"0014-2956","issn":["0014-2956","0945-5795","1432-1033"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Biochemistry","raw_type":"journal-article"},{"id":"pmid:5065743","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5065743","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W184399086","https://openalex.org/W1499128299","https://openalex.org/W1519782453","https://openalex.org/W1528159964","https://openalex.org/W1964729981","https://openalex.org/W1987484067","https://openalex.org/W1993452940","https://openalex.org/W2005290114","https://openalex.org/W2022174848","https://openalex.org/W2043239997","https://openalex.org/W2048893886","https://openalex.org/W2049077670","https://openalex.org/W2060995975","https://openalex.org/W2085474307","https://openalex.org/W2086668828","https://openalex.org/W2086913549","https://openalex.org/W2240965888","https://openalex.org/W2319822908","https://openalex.org/W2340724301","https://openalex.org/W4244321005"],"related_works":["https://openalex.org/W2043239997","https://openalex.org/W2042742367","https://openalex.org/W2067094091","https://openalex.org/W2086913549","https://openalex.org/W2073128682","https://openalex.org/W2064831730","https://openalex.org/W2416375357","https://openalex.org/W2416335236","https://openalex.org/W2029088716","https://openalex.org/W2092121080"],"abstract_inverted_index":{"The":[0,41],"globin":[1,43,71],"of":[2,62,68,76,82,112,120],"sheep":[3,89],"heart":[4],"myoglobin":[5,92],"was":[6,27],"first":[7,64,78],"cleaved":[8],"by":[9,18,52],"cyanogen":[10,47,85],"bromide":[11,48,86],"and":[12,21,32,44,72,90,115],"the":[13,33,45,53,60,63,69,74,77,83,102,110,118,124],"resulting":[14],"fragments":[15],"were":[16,50],"fractionated":[17],"gel":[19],"filtration":[20],"preparative":[22],"paper":[23],"electrochromatography;":[24],"each":[25],"fragment":[26],"submitted":[28],"to":[29,109,117],"endopeptidase":[30],"digestion":[31],"complete":[34],"amino":[35,104],"acid":[36,105],"sequence":[37,61,75],"has":[38],"been":[39],"determined.":[40],"intact":[42,70],"median":[46,84],"peptide":[49],"analysed":[51],"protein":[54],"sequanator":[55],"(Edman).":[56],"This":[57],"analysis":[58],"confirmed":[59],"46":[65],"N-terminal":[66,80],"residues":[67,81,97],"established":[73],"39":[79],"peptide.":[87],"Between":[88],"beef":[91],"six":[93,103],"differences":[94],"over":[95],"153":[96],"can":[98],"be":[99],"noticed;":[100],"among":[101],"replacements,":[106],"two":[107,113],"correspond":[108],"exchange":[111,119],"bases":[114],"four":[116],"one":[121],"base":[122],"in":[123],"coding":[125],"triplets.":[126]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-05-12T00:00:00"}