{"id":"https://openalex.org/W424724300","doi":null,"title":"Quantitative Study of Clostridium difficile Incidence Related to Influenza and Antimicrobial Use","display_name":"Quantitative Study of Clostridium difficile Incidence Related to Influenza and Antimicrobial Use","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W424724300","mag":"424724300"},"language":"en","primary_location":{"id":"pmh:oai:scholarworks.waldenu.edu:dissertations-1613","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.waldenu.edu/dissertations/614","pdf_url":"https://scholarworks.waldenu.edu/cgi/viewcontent.cgi?article=1613&context=dissertations","source":{"id":"https://openalex.org/S4377196507","display_name":"ScholarWorks (Walden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I80046288","host_organization_name":"Walden University","host_organization_lineage":["https://openalex.org/I80046288"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Walden Dissertations and Doctoral Studies","raw_type":"text"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://scholarworks.waldenu.edu/cgi/viewcontent.cgi?article=1613&context=dissertations","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004589426","display_name":"Eileen M. Yaeger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80046288","display_name":"Walden University","ror":"https://ror.org/02qp2hh41","country_code":"US","type":"education","lineage":["https://openalex.org/I80046288"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eileen M. Yaeger","raw_affiliation_strings":["Walden Univ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walden Univ","institution_ids":["https://openalex.org/I80046288"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5004589426"],"corresponding_institution_ids":["https://openalex.org/I80046288"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11000","display_name":"Infection Control in Healthcare","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clostridium-difficile-infection","display_name":"Clostridium difficile infection","score":0.9990000128746033},{"id":"https://openalex.org/keywords/influenza","display_name":"influenza","score":0.859000027179718},{"id":"https://openalex.org/keywords/antiviral-therapy","display_name":"antiviral therapy","score":0.6729999780654907},{"id":"https://openalex.org/keywords/antibiotic-use","display_name":"antibiotic use","score":0.9100000262260437},{"id":"https://openalex.org/keywords/hospitalized-patients","display_name":"hospitalized patients","score":0.6320000290870667},{"id":"https://openalex.org/keywords/inappropriate-prescribing","display_name":"inappropriate prescribing","score":0.6639999747276306},{"id":"https://openalex.org/keywords/antibiotic-stewardship","display_name":"antibiotic stewardship","score":0.9629999995231628},{"id":"https://openalex.org/keywords/man-environment-interaction","display_name":"man-environment interaction","score":0.7369999885559082}],"concepts":[{"id":"https://openalex.org/C2994496256","wikidata":"https://www.wikidata.org/wiki/Q27031090","display_name":"Clostridium difficile","level":3,"score":0.7794069051742554},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.6243398189544678},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.5485997796058655},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.5296879410743713},{"id":"https://openalex.org/C2908810495","wikidata":"https://www.wikidata.org/wiki/Q327663","display_name":"Clostridium Infections","level":4,"score":0.5119503736495972},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.4615402817726135},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40401753783226013},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.28969892859458923},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1667540967464447},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.09661245346069336},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.09030172228813171},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.06006726622581482},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:scholarworks.waldenu.edu:dissertations-1613","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.waldenu.edu/dissertations/614","pdf_url":"https://scholarworks.waldenu.edu/cgi/viewcontent.cgi?article=1613&context=dissertations","source":{"id":"https://openalex.org/S4377196507","display_name":"ScholarWorks (Walden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I80046288","host_organization_name":"Walden University","host_organization_lineage":["https://openalex.org/I80046288"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Walden Dissertations and Doctoral Studies","raw_type":"text"},{"id":"mag:424724300","doi":null,"is_oa":false,"landing_page_url":"https://scholarworks.waldenu.edu/cgi/viewcontent.cgi?article=1613&context=dissertations","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:scholarworks.waldenu.edu:dissertations-1613","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.waldenu.edu/dissertations/614","pdf_url":"https://scholarworks.waldenu.edu/cgi/viewcontent.cgi?article=1613&context=dissertations","source":{"id":"https://openalex.org/S4377196507","display_name":"ScholarWorks (Walden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I80046288","host_organization_name":"Walden University","host_organization_lineage":["https://openalex.org/I80046288"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Walden Dissertations and Doctoral Studies","raw_type":"text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W424724300.pdf","grobid_xml":"https://content.openalex.org/works/W424724300.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W165480572","https://openalex.org/W1482945316","https://openalex.org/W1559887231","https://openalex.org/W1593315707","https://openalex.org/W1714723801","https://openalex.org/W1845848707","https://openalex.org/W1886211768","https://openalex.org/W1924942505","https://openalex.org/W1965964455","https://openalex.org/W1973425330","https://openalex.org/W1975101868","https://openalex.org/W1986144709","https://openalex.org/W2008062441","https://openalex.org/W2010760898","https://openalex.org/W2011924980","https://openalex.org/W2019105812","https://openalex.org/W2025473925","https://openalex.org/W2037557484","https://openalex.org/W2038909070","https://openalex.org/W2040684206","https://openalex.org/W2047844316","https://openalex.org/W2054513528","https://openalex.org/W2073113652","https://openalex.org/W2076155791","https://openalex.org/W2080669113","https://openalex.org/W2083475779","https://openalex.org/W2087484885","https://openalex.org/W2088836366","https://openalex.org/W2096454911","https://openalex.org/W2107048829","https://openalex.org/W2107587279","https://openalex.org/W2109057963","https://openalex.org/W2110319056","https://openalex.org/W2116573698","https://openalex.org/W2129296397","https://openalex.org/W2131450981","https://openalex.org/W2136021420","https://openalex.org/W2139094271","https://openalex.org/W2144998000","https://openalex.org/W2155314544","https://openalex.org/W2167717276","https://openalex.org/W2168220466","https://openalex.org/W2321330274","https://openalex.org/W2321501255","https://openalex.org/W2330223144","https://openalex.org/W2413968773","https://openalex.org/W2417178017","https://openalex.org/W3022992683","https://openalex.org/W4247442802"],"related_works":["https://openalex.org/W2107961487","https://openalex.org/W2139094271","https://openalex.org/W7220380209","https://openalex.org/W2154099105","https://openalex.org/W3097652450","https://openalex.org/W3032882539","https://openalex.org/W2918446712","https://openalex.org/W2203528962","https://openalex.org/W2200466812","https://openalex.org/W4311531827"],"abstract_inverted_index":{"In":[0],"the":[1,52,62,79,119,130,134,163,240],"United":[2],"States,":[3],"influenza":[4,66,218],"causes":[5],"approximately":[6],"36,000":[7],"deaths":[8,38],"and":[9,30,39,68,91,98,133,221],"over":[10,40],"200,000":[11],"hospitalizations":[12,42],"each":[13],"year":[14],"with":[15,36,111,230],"elderly":[16],"most":[17],"often":[18],"affected.":[19],"Clostridium":[20],"difficile":[21],"infection":[22],"(CDI)":[23],"is":[24],"another":[25],"major":[26],"health":[27,33],"care":[28],"challenge":[29],"pressing":[31],"public":[32],"issue":[34],"associated":[35],"14,000":[37],"335,000":[41],"annually.":[43],"The":[44,106,153],"use":[45,70,172,180,191],"of":[46,54,64,83,104,122,124,137,142,170,200,205,242,249],"antibiotics":[47],"has":[48],"been":[49],"implicated":[50],"in":[51,71,78],"development":[53,73,199],"CDI.":[55],"This":[56],"study's":[57],"purpose":[58],"was":[59,147,214],"to":[60,159,217],"test":[61,116,139],"relationship":[63],"seasonal":[65,231],"incidence":[67],"antiviral/antibiotic":[69],"CDI":[72,143,201],"among":[74],"hospitalized":[75],"patients.":[76],"Grounded":[77],"epidemiologic":[80],"wheel":[81],"model":[82],"man-environment":[84],"interactions,":[85],"this":[86],"retrospective":[87],"observational":[88],"study":[89,154],"described":[90],"analyzed":[92],"data":[93],"from":[94,101],"a":[95,102,112],"proprietary,":[96],"laboratory,":[97],"pharmacy-based":[99],"system":[100],"cohort":[103],"hospitals.":[105],"association":[107],"between":[108],"147":[109],"patients":[110,220],"diagnosis":[113,141],"and/or":[114,189],"positive":[115,138,219,235],"for":[117,162,226,234],"influenza,":[118],"independent":[120],"variables":[121],"delivery":[123],"antivirals/antibiotics":[125],"(n":[126,144],"=":[127,145,174,177,182,185,193,196],"130)":[128],"during":[129],"patient's":[131],"hospitalization,":[132],"dependent":[135],"variable":[136],"or":[140,187],"17)":[146],"tested":[148],"using":[149],"multiple":[150],"logistic":[151],"regressions.":[152],"results":[155],"did":[156],"not":[157],"prove":[158],"be":[160],"significant":[161],"3":[164],"research":[165],"questions,":[166],"suggesting":[167],"no":[168],"impact":[169],"antiviral":[171,188,212],"(R2":[173,181,192],".05,":[175,183],"p":[176,184,195],".336),":[178],"antibiotic":[179,190,243],".290),":[186],".04,":[194],".382)":[197],"on":[198],"within":[202],"60":[203],"days":[204],"discharge.":[206],"However,":[207],"findings":[208],"indicated":[209],"that":[210,222],"recommended":[211],"medication":[213],"inconsistently":[215],"administered":[216],"inappropriate":[223],"prescribing":[224],"patterns":[225],"antimicrobial":[227],"agents":[228],"coincided":[229],"influenza.":[232],"Implications":[233],"social":[236],"change":[237],"include":[238],"confirming":[239],"importance":[241],"stewardship":[244],"as":[245],"an":[246],"essential":[247],"aspect":[248],"quality":[250],"healthcare.":[251]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}