{"id":"https://openalex.org/W4246793367","doi":"https://doi.org/10.1093/oxfordhb/9780199764228.013.8","title":"Positron Emission Tomography","display_name":"Positron Emission Tomography","publication_year":2014,"publication_date":"2014-10-02","ids":{"openalex":"https://openalex.org/W4246793367","doi":"https://doi.org/10.1093/oxfordhb/9780199764228.013.8"},"language":"en","primary_location":{"id":"doi:10.1093/oxfordhb/9780199764228.013.8","doi":"https://doi.org/10.1093/oxfordhb/9780199764228.013.8","is_oa":false,"landing_page_url":"https://doi.org/10.1093/oxfordhb/9780199764228.013.8","pdf_url":null,"source":{"id":"https://openalex.org/S4306463708","display_name":"Oxford University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxford Handbooks Online","raw_type":"book"},"volume":null,"type":"book","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027840618","display_name":"Shalini Narayana","orcid":"https://orcid.org/0000-0002-0116-5785","observed_orcids":["https://orcid.org/0000-0002-0116-5785"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shalini Narayana","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001179545","display_name":"Babak Saboury","orcid":"https://orcid.org/0000-0002-8632-6292","observed_orcids":["https://orcid.org/0000-0002-8632-6292"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Babak Saboury","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033687321","display_name":"Andrew B. Newberg","orcid":"https://orcid.org/0000-0001-8230-1752","observed_orcids":["https://orcid.org/0000-0001-8230-1752"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew B. Newberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091318917","display_name":"Andrew C. Papanicolaou","orcid":"https://orcid.org/0000-0002-5543-1268","observed_orcids":["https://orcid.org/0000-0002-5543-1268"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew C. Papanicolaou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5088003622","display_name":"Abass A. Alavi","orcid":"https://orcid.org/0000-0002-2442-7901","observed_orcids":["https://orcid.org/0000-0002-2442-7901"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Abass Alavi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.41359773,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/positron-emission-tomography","display_name":"positron emission tomography","score":1.0},{"id":"https://openalex.org/keywords/positron-emission","display_name":"positron emission","score":0.7649999856948853},{"id":"https://openalex.org/keywords/cerebral-blood-flow","display_name":"cerebral blood flow","score":0.9330000281333923},{"id":"https://openalex.org/keywords/cerebral-glucose-metabolism","display_name":"brain glucose metabolism","score":0.7459999918937683},{"id":"https://openalex.org/keywords/cerebral-metabolic-rate-for-oxygen","display_name":"cerebral oxygen consumption","score":0.9639999866485596},{"id":"https://openalex.org/keywords/pet-ct","display_name":"PET/CT","score":0.8130000233650208},{"id":"https://openalex.org/keywords/pet-mri","display_name":"PET/MRI","score":0.9810000061988831},{"id":"https://openalex.org/keywords/patient-preparation","display_name":"patient preparation","score":0.6830000281333923},{"id":"https://openalex.org/keywords/scan-parameters","display_name":"scanning parameters","score":0.9419999718666077}],"concepts":[{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.9296121597290039},{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.6881465911865234},{"id":"https://openalex.org/C3017724952","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Pet imaging","level":3,"score":0.6185921430587769},{"id":"https://openalex.org/C112390072","wikidata":"https://www.wikidata.org/wiki/Q4955834","display_name":"Brain positron emission tomography","level":4,"score":0.605133593082428},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.5991459488868713},{"id":"https://openalex.org/C202100949","wikidata":"https://www.wikidata.org/wiki/Q3229","display_name":"Positron","level":3,"score":0.5748646855354309},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.538321316242218},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.506777822971344},{"id":"https://openalex.org/C136339569","wikidata":"https://www.wikidata.org/wiki/Q1142297","display_name":"Molecular imaging","level":3,"score":0.498291015625},{"id":"https://openalex.org/C37097830","wikidata":"https://www.wikidata.org/wiki/Q1357356","display_name":"Positron emission","level":3,"score":0.4786069095134735},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.4353259205818176},{"id":"https://openalex.org/C182752723","wikidata":"https://www.wikidata.org/wiki/Q1474590","display_name":"Functional imaging","level":2,"score":0.4156542420387268},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.40788793563842773},{"id":"https://openalex.org/C29331040","wikidata":"https://www.wikidata.org/wiki/Q7239554","display_name":"Preclinical imaging","level":3,"score":0.39006033539772034},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38698652386665344},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.27712303400039673},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.245559960603714},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.21393829584121704},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.16719767451286316},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.08262377977371216},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.07376280426979065},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.0},{"id":"https://openalex.org/C147120987","wikidata":"https://www.wikidata.org/wiki/Q2225","display_name":"Electron","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/oxfordhb/9780199764228.013.8","doi":"https://doi.org/10.1093/oxfordhb/9780199764228.013.8","is_oa":false,"landing_page_url":"https://doi.org/10.1093/oxfordhb/9780199764228.013.8","pdf_url":null,"source":{"id":"https://openalex.org/S4306463708","display_name":"Oxford University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxford Handbooks Online","raw_type":"book"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2407603807","https://openalex.org/W2502928391","https://openalex.org/W2007125162","https://openalex.org/W4226048113","https://openalex.org/W43992446","https://openalex.org/W4408148074","https://openalex.org/W2078227959","https://openalex.org/W3121104263","https://openalex.org/W4234414356","https://openalex.org/W2411110861"],"abstract_inverted_index":{"Positron":[0],"emission":[1],"tomography":[2],"(PET)":[3],"is":[4],"an":[5],"imaging":[6,85,118],"method":[7],"that":[8],"utilizes":[9],"compounds":[10],"labeled":[11],"with":[12],"positron-emitting":[13],"radioisotopes":[14],"as":[15,41,43,52,68],"molecular":[16],"probes":[17],"to":[18],"evaluate":[19],"different":[20],"neurophysiological":[21],"processes":[22],"quantitatively":[23],"and":[24,36,38,56,58,71,83,89,107],"noninvasively.":[25],"This":[26],"chapter":[27],"provides":[28],"a":[29],"background":[30],"regarding":[31],"positron":[32],"emission,":[33],"radiotracer":[34],"chemistry,":[35],"detector":[37],"scanner":[39],"instrumentation,":[40],"well":[42],"analytical":[44],"methods":[45],"for":[46,92],"evaluating":[47],"basic":[48],"brain":[49],"physiology,":[50],"such":[51,67],"cerebral":[53],"blood":[54,81],"flow":[55,82],"oxygen":[57],"glucose":[59],"metabolism.":[60],"The":[61],"methodological":[62],"aspects":[63],"of":[64,78,80,95,116],"PET":[65,103,117],"imaging,":[66,104],"patient":[69],"preparation":[70],"optimal":[72],"scanning":[73],"parameters,":[74],"are":[75,98,109,119],"discussed.":[76],"Examples":[77],"application":[79],"metabolic":[84],"in":[86,102],"both":[87],"research":[88],"clinical":[90],"scenarios":[91],"the":[93,113],"evaluation":[94],"normal":[96],"neurophysiology":[97],"provided.":[99],"Recent":[100],"advances":[101],"including":[105],"PET-CT":[106],"PET-MRI,":[108],"also":[110],"described.":[111],"Finally,":[112],"unique":[114],"strengths":[115],"highlighted.":[120]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2022-05-12T00:00:00"}