{"id":"https://openalex.org/W4245736586","doi":"https://doi.org/10.1200/jco.2009.27.18s.cra1500","title":"Non-small cell lung cancer and estrogen plus progestin use in postmenopausal women in the Women's Health Initiative randomized clinical trial","display_name":"Non-small cell lung cancer and estrogen plus progestin use in postmenopausal women in the Women's Health Initiative randomized clinical trial","publication_year":2009,"publication_date":"2009-06-20","ids":{"openalex":"https://openalex.org/W4245736586","doi":"https://doi.org/10.1200/jco.2009.27.18s.cra1500"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2009.27.18s.cra1500","doi":"https://doi.org/10.1200/jco.2009.27.18s.cra1500","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2009.27.18s.cra1500","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004840750","display_name":"Rowan T. Chlebowski","orcid":"https://orcid.org/0000-0002-4212-6184","observed_orcids":["https://orcid.org/0000-0002-4212-6184"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. T. Chlebowski","raw_affiliation_strings":["LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210089486","https://openalex.org/I4210090317","https://openalex.org/I63135867","https://openalex.org/I63190737","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000445673","display_name":"Ann G. Schwartz","orcid":"https://orcid.org/0000-0002-9525-1157","observed_orcids":["https://orcid.org/0000-0002-9525-1157"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Schwartz","raw_affiliation_strings":["LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210089486","https://openalex.org/I4210090317","https://openalex.org/I63135867","https://openalex.org/I63190737","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035640724","display_name":"Heather A. Wakelee","orcid":"https://orcid.org/0000-0003-1136-980X","observed_orcids":["https://orcid.org/0000-0003-1136-980X"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Wakelee","raw_affiliation_strings":["LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210089486","https://openalex.org/I4210090317","https://openalex.org/I63135867","https://openalex.org/I63190737","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043491217","display_name":"Garnet L. Anderson","orcid":"https://orcid.org/0000-0001-5087-7837","observed_orcids":["https://orcid.org/0000-0001-5087-7837"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G. L. Anderson","raw_affiliation_strings":["LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210089486","https://openalex.org/I4210090317","https://openalex.org/I63135867","https://openalex.org/I63190737","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067389037","display_name":"Marcia L. Stefanick","orcid":"https://orcid.org/0000-0002-0284-6996","observed_orcids":["https://orcid.org/0000-0002-0284-6996"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. L. Stefanick","raw_affiliation_strings":["LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210089486","https://openalex.org/I4210090317","https://openalex.org/I63135867","https://openalex.org/I63190737","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049411008","display_name":"JoAnn Elisabeth Manson","orcid":"https://orcid.org/0000-0002-9426-7595","observed_orcids":["https://orcid.org/0000-0002-9426-7595"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. E. Manson","raw_affiliation_strings":["LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210089486","https://openalex.org/I4210090317","https://openalex.org/I63135867","https://openalex.org/I63190737","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045549260","display_name":"Jason W. Chien","orcid":"https://orcid.org/0000-0003-4695-2923","observed_orcids":["https://orcid.org/0000-0003-4695-2923"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. W. Chien","raw_affiliation_strings":["LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210089486","https://openalex.org/I4210090317","https://openalex.org/I63135867","https://openalex.org/I63190737","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":null,"display_name":"C. Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Chen","raw_affiliation_strings":["LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210089486","https://openalex.org/I4210090317","https://openalex.org/I63135867","https://openalex.org/I63190737","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016111941","display_name":"Jean Wactawski\u2010Wende","orcid":"https://orcid.org/0000-0003-3096-9595","observed_orcids":["https://orcid.org/0000-0003-3096-9595"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Wactawski-Wende","raw_affiliation_strings":["LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210089486","https://openalex.org/I4210090317","https://openalex.org/I63135867","https://openalex.org/I63190737","https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108417306","display_name":"Margery L S Gass","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Gass","raw_affiliation_strings":["LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LABioMed, Torrance, CA; Karmanos Cancer Institute, Detroit, MI; Stanford University School of Medicine, Palo Alto, CA; Fred Hutchinson Cancer Research Center, Seattle, WA; Stanford University, Palo Alto, CA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University of Buffalo, Buffalo, NY; University of Cincinnati College of Medicine, Cincinnati, OH","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210089486","https://openalex.org/I4210090317","https://openalex.org/I63135867","https://openalex.org/I63190737","https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"18S","first_page":"CRA1500","last_page":"CRA1500"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.009499999694526196,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.007199999876320362,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-small-cell-lung-cancer","display_name":"non-small cell lung cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/estrogen-plus-progestin","display_name":"estrogen plus progestin","score":0.765999972820282},{"id":"https://openalex.org/keywords/hormone-replacement-therapy","display_name":"hormone replacement therapy","score":0.9449999928474426},{"id":"https://openalex.org/keywords/conjugated-equine-estrogens","display_name":"conjugated equine estrogens","score":0.9649999737739563},{"id":"https://openalex.org/keywords/medroxyprogesterone-acetate","display_name":"medroxyprogesterone acetate","score":1.0},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.9729999899864197},{"id":"https://openalex.org/keywords/lung-cancer-incidence","display_name":"lung cancer incidence","score":0.8450000286102295},{"id":"https://openalex.org/keywords/lung-cancer-mortality","display_name":"lung cancer mortality","score":0.9929999709129333},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.4569999873638153},{"id":"https://openalex.org/keywords/women-s-health-initiative","display_name":"Women's Health Initiative","score":0.8019999861717224},{"id":"https://openalex.org/keywords/sex-differences-in-cancer-risk","display_name":"sex differences in cancer risk","score":0.8059999942779541},{"id":"https://openalex.org/keywords/small-cell-lung-cancer","display_name":"small cell lung cancer","score":0.621999979019165},{"id":"https://openalex.org/keywords/breast-cancer-risk","display_name":"breast cancer risk","score":0.7799999713897705}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9093303084373474},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.7260215282440186},{"id":"https://openalex.org/C2776306185","wikidata":"https://www.wikidata.org/wiki/Q2823834","display_name":"Medroxyprogesterone acetate","level":3,"score":0.7169350385665894},{"id":"https://openalex.org/C2780733421","wikidata":"https://www.wikidata.org/wiki/Q1451732","display_name":"Women's Health Initiative","level":3,"score":0.6017345786094666},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6006930470466614},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.5892630815505981},{"id":"https://openalex.org/C2780275930","wikidata":"https://www.wikidata.org/wiki/Q1628266","display_name":"Hormone therapy","level":4,"score":0.5259205102920532},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4987211227416992},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.4815009832382202},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4615578353404999},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4287642538547516},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.41406935453414917},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.4044746160507202},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.39585036039352417},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.21245083212852478},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.11215335130691528},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.053852230310440063},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2009.27.18s.cra1500","doi":"https://doi.org/10.1200/jco.2009.27.18s.cra1500","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2009.27.18s.cra1500","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2138990570","https://openalex.org/W2159905085","https://openalex.org/W2088149372","https://openalex.org/W1843574618","https://openalex.org/W2288658528","https://openalex.org/W2088253889","https://openalex.org/W1986804648","https://openalex.org/W2043223338","https://openalex.org/W7098816367","https://openalex.org/W2124123514"],"abstract_inverted_index":{"CRA1500":[0],"Background:":[1],"Sex":[2],"differences":[3],"in":[4,50,94,104,158,177,247],"lung":[5,25,60,100,129,144,154],"cancer":[6,61,101,130,145,155,245,258,264],"outcome":[7],"suggest":[8,263],"a":[9,148,207,235],"potential":[10],"hormonal":[11],"influence;":[12],"however,":[13],"observational":[14],"studies":[15],"provide":[16],"mixed":[17],"findings":[18],"regarding":[19],"menopausal":[20],"hormone":[21,161],"therapy":[22],"(HT)":[23],"and":[24,63,80,111,121],"cancer.":[26],"Methods:":[27],"Secondary":[28],"analyses":[29],"of":[30,36,226,244],"the":[31,159,178,191,241],"WHI":[32],"randomized,":[33],"placebo-controlled":[34],"trial":[35,119],"daily":[37],"conjugated":[38],"equine":[39],"estrogen":[40],"(CEE,":[41],"0.625":[42],"mg)":[43,49],"plus":[44],"medroxyprogesterone":[45],"acetate":[46],"(MPA,":[47],"2.5":[48],"16,608":[51],"multi-ethnic":[52],"postmenopausal":[53],"women,":[54],"aged":[55],"50\u201379":[56],"were":[57,67,75,212],"conducted":[58],"on":[59,118,221],"incidence":[62,131],"mortality.":[64,146],"Lung":[65],"cancers":[66],"confirmed":[68],"by":[69,278],"medical":[70],"record":[71],"review.":[72],"Results:":[73],"Groups":[74],"balanced":[76],"for":[77,99,150,190,230,238,270],"age,":[78],"race/ethnicity,":[79],"prior":[81],"HT.":[82],"Smoking":[83],"status":[84],"was":[85,102,132,140,163,187],"also":[86],"comparable":[87,133],"(never":[88],"50%,":[89],"past":[90,109],"40%,":[91],"current":[92,105],"10%":[93],"both":[95],"groups).":[96],"Cumulative":[97],"risk":[98,237,259],"highest":[103],"(0.51%),":[106],"compared":[107],"to":[108,215],"(0.14%)":[110],"never":[112],"(0.04%)":[113],"smokers.":[114],"After":[115],"5.6":[116],"years":[117,123,233],"intervention":[120],"2.4":[122],"additional":[124],"follow-up":[125],"(median),":[126],"small":[127,142],"cell":[128,143,153],"between":[134],"randomization":[135,279,316],"groups":[136],"(total":[137],"n=26),":[138],"as":[139],"subsequent":[141],"Although":[147],"trend":[149],"more":[151,175,213],"non-small":[152],"(NSCLC)":[156],"diagnoses":[157,176],"active":[160],"group":[162,193,210,280],"not":[164],"significant":[165],"(p=0.12),":[166],"an":[167],"apparent":[168],"divergence":[169],"emerged":[170],"after":[171,184],"five":[172],"years,":[173],"with":[174,252],"CEE+MPA":[179,192,209,281],"group.":[180],"In":[181],"addition,":[182],"mortality":[183],"NSCLC":[185,218,239,274,291,301],"diagnosis":[186],"significantly":[188],"higher":[189,256],"(46.3%":[194],"vs":[195],"27.0%,":[196],"respectively,":[197],"hazard":[198],"ratio":[199],"(HR)":[200],"1.59,":[201],"95%":[202,284],"CI":[203,285],"1.03\u20132.46,":[204],"p=0.04).":[205],"As":[206],"result,":[208],"women":[211],"likely":[214],"die":[216],"from":[217],"than":[219],"those":[220],"placebo":[222],"(p=0.02).":[223],"Conclusions:":[224],"Use":[225],"CEE":[227],"+":[228],"MPA":[229],"over":[231],"5":[232],"increases":[234],"woman's":[236],"mortality,":[240],"leading":[242],"cause":[243],"death":[246],"women.":[248],"These":[249],"data,":[250],"together":[251],"recent":[253],"results":[254],"indicating":[255],"breast":[257],"(Cancer":[260],"Res":[261],"2009;69(2):78s),":[262],"impact":[265],"should":[266],"influence":[267],"risk-to-benefit":[268],"consideration":[269],"combined":[271],"HT":[272],"use.":[273],"outcomes":[275],"(annualized":[276],"%)":[277],"Placebo":[282],"HR":[283],"P-Value":[286],"N":[287,289],"%":[288,290],"Incidence":[292],"96":[293],"0.14%":[294],"72":[295],"0.11%":[296],"1.28":[297],"0.94,":[298],"1.73":[299],"0.12":[300],"Mortality":[302],"*":[303,311],"67":[304],"0.10%":[305],"39":[306],"0.06%":[307],"1.61":[308],"1.09\u20132.39":[309],"0.02":[310],"Analyses":[312],"begin":[313],"at":[314],"entry":[315],"Author":[317],"Disclosure":[318],"Employment":[319],"or":[320,323],"Leadership":[321],"Consultant":[322],"Advisory":[324],"Role":[325],"Stock":[326],"Ownership":[327],"Honoraria":[328],"Research":[329],"Funding":[330],"Expert":[331],"Testimony":[332],"Other":[333],"Remuneration":[334],"Amgen,":[335,341],"AstraZeneca,":[336,342],"Eli":[337,343],"Lilly,":[338,344],"Novartis,":[339,345],"Wyeth":[340,346],"Amgen":[347]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2022-05-12T00:00:00"}