{"id":"https://openalex.org/W4245484261","doi":"https://doi.org/10.1111/j.1572-0241.2001.03888.x","title":"Usefulness of positron emission tomography with fluorine-18-fluorodeoxyglucose for predicting outcome in patients with hepatocellular carcinoma","display_name":"Usefulness of positron emission tomography with fluorine-18-fluorodeoxyglucose for predicting outcome in patients with hepatocellular carcinoma","publication_year":2001,"publication_date":"2001-06-01","ids":{"openalex":"https://openalex.org/W4245484261","doi":"https://doi.org/10.1111/j.1572-0241.2001.03888.x","pmid":"https://pubmed.ncbi.nlm.nih.gov/11419843"},"language":"en","primary_location":{"id":"doi:10.1111/j.1572-0241.2001.03888.x","doi":"https://doi.org/10.1111/j.1572-0241.2001.03888.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1572-0241.2001.03888.x","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110062041","display_name":"Susumu Shiomi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Susumu Shiomi","raw_affiliation_strings":["Third Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Third Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan","institution_ids":["https://openalex.org/I317356780","https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111692361","display_name":"Shuhei Nishiguchi","orcid":"https://orcid.org/0009-0002-2356-0409","observed_orcids":["https://orcid.org/0009-0002-2356-0409"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shuhei Nishiguchi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112089012","display_name":"Hirotaka Ishizu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hirotaka Ishizu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108897626","display_name":"Y Iwata","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yoshinori Iwata","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Nobumitsu Sasaki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nobumitsu Sasaki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067647579","display_name":"Akihiro Tamori","orcid":"https://orcid.org/0000-0001-9119-4864","observed_orcids":["https://orcid.org/0000-0001-9119-4864"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Akihiro Tamori","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045903387","display_name":"Daiki Habu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daiki Habu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Tadashi Takeda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tadashi Takeda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049137704","display_name":"Shoji Kubo","orcid":"https://orcid.org/0000-0002-4353-8033","observed_orcids":["https://orcid.org/0000-0002-4353-8033"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shoji Kubo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"Hironobu Ochi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hironobu Ochi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":4.7879,"has_fulltext":false,"cited_by_count":131,"citation_normalized_percentile":{"value":0.95292091,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"96","issue":"6","first_page":"1877","last_page":"1880"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.7139000296592712,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.7139000296592712,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.24770000576972961,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.9959999918937683},{"id":"https://openalex.org/keywords/fdg-pet","display_name":"FDG-PET","score":0.9929999709129333},{"id":"https://openalex.org/keywords/standardized-uptake-value","display_name":"standardized uptake value","score":0.7170000076293945},{"id":"https://openalex.org/keywords/suv-ratio","display_name":"SUV ratio","score":0.8600000143051147},{"id":"https://openalex.org/keywords/tumor-growth-rate","display_name":"tumor growth rate","score":0.699999988079071},{"id":"https://openalex.org/keywords/tumor-volume-doubling-time","display_name":"tumor volume doubling time","score":0.8629999756813049},{"id":"https://openalex.org/keywords/survival-prediction","display_name":"survival prediction","score":0.7990000247955322},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8840000033378601},{"id":"https://openalex.org/keywords/tumor-number","display_name":"tumor number","score":0.7710000276565552}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8634088635444641},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.7502852082252502},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.7306982278823853},{"id":"https://openalex.org/C199374082","wikidata":"https://www.wikidata.org/wiki/Q907080","display_name":"Standardized uptake value","level":3,"score":0.7142210006713867},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.6737562417984009},{"id":"https://openalex.org/C2777415128","wikidata":"https://www.wikidata.org/wiki/Q419849","display_name":"Fluorodeoxyglucose","level":3,"score":0.6048339009284973},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.46663743257522583},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.44130077958106995},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23926550149917603}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014055","descriptor_name":"Tomography, Emission-Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1572-0241.2001.03888.x","doi":"https://doi.org/10.1111/j.1572-0241.2001.03888.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1572-0241.2001.03888.x","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Gastroenterology","raw_type":"journal-article"},{"id":"doi:10.1016/s0002-9270(01)02451-0","doi":"https://doi.org/10.1016/s0002-9270(01)02451-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0002-9270(01)02451-0","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Gastroenterology","raw_type":"journal-article"},{"id":"pmid:11419843","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11419843","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of gastroenterology","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W79233028","https://openalex.org/W161377529","https://openalex.org/W1533884426","https://openalex.org/W1580788756","https://openalex.org/W1606640699","https://openalex.org/W1780739692","https://openalex.org/W1831080987","https://openalex.org/W1890653303","https://openalex.org/W1944710770","https://openalex.org/W1963747703","https://openalex.org/W1964015820","https://openalex.org/W2029828243","https://openalex.org/W2051077516","https://openalex.org/W2051639324","https://openalex.org/W2053813768","https://openalex.org/W2060123467","https://openalex.org/W2077015829","https://openalex.org/W2097912113","https://openalex.org/W2102322990","https://openalex.org/W2121707384","https://openalex.org/W2143594378","https://openalex.org/W2145788008","https://openalex.org/W2165298960","https://openalex.org/W2250044440","https://openalex.org/W2328838310","https://openalex.org/W2404588481","https://openalex.org/W2591170673","https://openalex.org/W3147894994"],"related_works":["https://openalex.org/W2406709993","https://openalex.org/W2021545571","https://openalex.org/W2009479472","https://openalex.org/W1498255743","https://openalex.org/W2053156274","https://openalex.org/W1968648271","https://openalex.org/W1999282736","https://openalex.org/W2034007337","https://openalex.org/W2207690407","https://openalex.org/W7071764973"],"abstract_inverted_index":{"OBJECTIVES:":[0],"The":[1,67,114,171,215],"present":[2],"study":[3],"was":[4,27,43,57,73,85,104,175,219],"designed":[5],"to":[6,242],"assess":[7],"the":[8,46,52,61,65,80,89,93,107,111,121,139,142,145,186,189,191,228,233,255,258,266],"usefulness":[9],"of":[10,40,48,64,96,110,120,124,141,152,159,188,198,257,260,268],"positron":[11],"emission":[12],"tomography":[13],"with":[14,22,32,129,136,227,272],"fluorine-18-fluorodeoxyglucose":[15],"(FDG-PET)":[16],"for":[17,76,254,265],"predicting":[18],"outcome":[19,269],"in":[20,29,178,182,221,270],"patients":[21,31,146,192,271],"hepatocellular":[23,33,125,261,273],"carcinoma.":[24,34,274],"METHODS:":[25],"FDG-PET":[26,249],"performed":[28],"48":[30],"For":[35],"quantitative":[36],"evaluation,":[37],"a":[38],"region":[39,63],"interest":[41],"(ROI)":[42],"placed":[44,59],"over":[45,60],"area":[47],"maximum":[49],"activity":[50,69,91],"within":[51,70],"lesion.":[53],"A":[54],"background":[55],"ROI":[56,72],"then":[58],"nontumor":[62],"liver.":[66],"average":[68],"each":[71],"subsequently":[74],"corrected":[75],"radioactive":[77],"decay,":[78],"and":[79,164,209,236],"standardized":[81],"uptake":[82],"value":[83],"(SUV)":[84],"calculated":[86],"by":[87,92],"dividing":[88],"tissue":[90],"injected":[94],"dose":[95],"radioactivity":[97],"per":[98],"unit":[99],"body":[100],"weight.":[101],"SUV":[102,130,143,157,167,207,213,234],"ratio":[103,109,131,158,168,235],"expressed":[105],"as":[106,118],"tumor-to-nontumor":[108],"SUV.":[112,137],"RESULTS:":[113],"tumor-volume":[115],"doubling":[116],"time,":[117],"index":[119],"growth":[122],"rate":[123,174,218],"carcinoma,":[126],"correlated":[127],"significantly":[128,176,240],"but":[132,263],"did":[133],"not":[134,252],"correlate":[135],"On":[138,185,224],"basis":[140,187],"ratio,":[144],"were":[147,193,239],"divided":[148,194],"into":[149,195],"two":[150,196],"groups":[151,197],"similar":[153,220],"size:":[154,201],"group":[155,165,179,183,202,210],"A,":[156],"<":[160,204],"or":[161,205],"=":[162,206],"1.5;":[163],"B,":[166],">":[169,212],"1.5.":[170],"cumulative":[172,216],"survival":[173,217],"lower":[177],"B":[180],"than":[181],"A.":[184],"SUV,":[190],"roughly":[199],"equal":[200],"C,":[203],"2.6;":[208],"D,":[211],"2.6.":[214],"these":[222],"groups.":[223],"regression":[225],"analysis":[226],"Cox":[229],"proportional":[230],"hazards":[231],"model,":[232],"tumor":[237],"number":[238],"related":[241],"survival.":[243],"CONCLUSIONS:":[244],"These":[245],"results":[246],"suggest":[247],"that":[248],"is":[250],"useful":[251],"only":[253],"evaluation":[256],"malignancy":[259],"carcinoma":[262],"also":[264],"prediction":[267]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":11}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2022-05-12T00:00:00"}