{"id":"https://openalex.org/W4244595091","doi":"https://doi.org/10.1016/b978-012466044-1/50516-0","title":"L-selectin","display_name":"L-selectin","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W4244595091","doi":"https://doi.org/10.1016/b978-012466044-1/50516-0"},"language":"en","primary_location":{"id":"doi:10.1016/b978-012466044-1/50516-0","doi":"https://doi.org/10.1016/b978-012466044-1/50516-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-012466044-1/50516-0","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Gene Knockout FactsBook","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W564011763","display_name":"The Gene Knockout FactsBook"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000800493","display_name":"Tak W. Mak","orcid":"https://orcid.org/0000-0001-6766-861X","observed_orcids":["https://orcid.org/0000-0001-6766-861X","https://orcid.org/0000-0002-0459-4112"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2802654988","display_name":"Princess Margaret Cancer Centre","ror":"https://ror.org/03zayce58","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2802654988"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Tak W. Mak","raw_affiliation_strings":["Amgen Institute, Department of Medicial Biophysics, University of Toronto, Toronto, Canada","Department of Immunology, University of Toronto, Toronto, Canada","Editor-in-chief Ontario Cancer Institute/Princess Margaret Hospital, University of Toronto, Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amgen Institute, Department of Medicial Biophysics, University of Toronto, Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Department of Immunology, University of Toronto, Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Editor-in-chief Ontario Cancer Institute/Princess Margaret Hospital, University of Toronto, Toronto, Canada","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I2802654988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059310975","display_name":"Josef Martin Penninger","orcid":"https://orcid.org/0000-0002-8194-3777","observed_orcids":["https://orcid.org/0000-0002-8194-3777"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2802654988","display_name":"Princess Margaret Cancer Centre","ror":"https://ror.org/03zayce58","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2802654988"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Josef Penninger","raw_affiliation_strings":["Amgen Institute, Department of Medical Biophysics, University of Toronto, Canada","Department of Immunology, University of Toronto, Toronto, Canada","Ontario Cancer Institute/Princess Margaret Hospital, University of Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amgen Institute, Department of Medical Biophysics, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Department of Immunology, University of Toronto, Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Ontario Cancer Institute/Princess Margaret Hospital, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I2802654988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111715744","display_name":"John Roder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1291836623","display_name":"Mount Sinai Hospital","ror":"https://ror.org/05deks119","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1291836623","https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I210557978","display_name":"Lunenfeld-Tanenbaum Research Institute","ror":"https://ror.org/01s5axj25","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1291836623","https://openalex.org/I210557978","https://openalex.org/I4210130843"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"John Roder","raw_affiliation_strings":["Department of Immunology, University of Toronto, Canada","Department of Molecular and Medical Genetics, University of Toronto, Canada","Program in Development and Fetal Health, Samuel Lunenfeld. Research Institute, Mount Sinai Hospital, University of Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Department of Molecular and Medical Genetics, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Program in Development and Fetal Health, Samuel Lunenfeld. Research Institute, Mount Sinai Hospital, University of Toronto, Canada","institution_ids":["https://openalex.org/I1291836623","https://openalex.org/I185261750","https://openalex.org/I210557978"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011985445","display_name":"Janet Rossant","orcid":"https://orcid.org/0000-0002-3731-5466","observed_orcids":["https://orcid.org/0000-0002-3731-5466"]},"institutions":[{"id":"https://openalex.org/I1291836623","display_name":"Mount Sinai Hospital","ror":"https://ror.org/05deks119","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1291836623","https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I210557978","display_name":"Lunenfeld-Tanenbaum Research Institute","ror":"https://ror.org/01s5axj25","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1291836623","https://openalex.org/I210557978","https://openalex.org/I4210130843"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Janet Rossant","raw_affiliation_strings":["Department of Molecular and Medical Genetics, University of Toronto, Canada","Department of Obstetrics/Gynaecology, University of Toronto, Canada","Program in Development and Fetal Health, Samuel Lunenfeld Research Institute, Mount Sinai Hospital University of Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Medical Genetics, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Department of Obstetrics/Gynaecology, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Program in Development and Fetal Health, Samuel Lunenfeld Research Institute, Mount Sinai Hospital University of Toronto, Canada","institution_ids":["https://openalex.org/I1291836623","https://openalex.org/I185261750","https://openalex.org/I210557978"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023514711","display_name":"Mary E. Saunders","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mary Saunders","raw_affiliation_strings":["Senior Scientist/Scientific Editor Amgen Institute, Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Senior Scientist/Scientific Editor Amgen Institute, Toronto, Canada","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.48321168,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"938","last_page":"941"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.7621999979019165,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.7621999979019165,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.2045000046491623,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11469","display_name":"Lymphatic System and Diseases","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/l-selectin","display_name":"L-selectin","score":1.0},{"id":"https://openalex.org/keywords/lymphocyte-homing","display_name":"lymphocyte homing","score":0.8510000109672546},{"id":"https://openalex.org/keywords/high-endothelial-venules","display_name":"high endothelial venules","score":0.949999988079071},{"id":"https://openalex.org/keywords/lymphocyte-trafficking","display_name":"lymphocyte migration","score":0.6349999904632568},{"id":"https://openalex.org/keywords/peripheral-lymph-nodes","display_name":"peripheral lymph nodes","score":0.7099999785423279},{"id":"https://openalex.org/keywords/peyer-s-patches","display_name":"Peyer's patches","score":0.8690000176429749},{"id":"https://openalex.org/keywords/mesenteric-lymph-nodes","display_name":"mesenteric lymph nodes","score":0.7689999938011169},{"id":"https://openalex.org/keywords/humoral-immune-response","display_name":"humoral immune response","score":0.7910000085830688},{"id":"https://openalex.org/keywords/t-independent-antigens","display_name":"T-independent antigens","score":0.7210000157356262},{"id":"https://openalex.org/keywords/t-cell-dependent-antigens","display_name":"T-dependent antigens","score":0.9819999933242798},{"id":"https://openalex.org/keywords/igm","display_name":"IgM","score":0.5540000200271606},{"id":"https://openalex.org/keywords/igg","display_name":"IgG","score":0.878000020980835},{"id":"https://openalex.org/keywords/secondary-immune-response","display_name":"secondary immune response","score":0.6620000004768372},{"id":"https://openalex.org/keywords/delayed-type-hypersensitivity","display_name":"delayed-type hypersensitivity","score":0.9150000214576721}],"concepts":[{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6965117454528809},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6528725624084473},{"id":"https://openalex.org/C2780801004","wikidata":"https://www.wikidata.org/wiki/Q1415366","display_name":"Immunization","level":3,"score":0.6473990678787231},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5973044633865356},{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.5916695594787598},{"id":"https://openalex.org/C2779237934","wikidata":"https://www.wikidata.org/wiki/Q7643652","display_name":"Mesenteric lymph nodes","level":3,"score":0.5790415406227112},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.5351325869560242},{"id":"https://openalex.org/C2779835222","wikidata":"https://www.wikidata.org/wiki/Q4042403","display_name":"L-selectin","level":3,"score":0.46588462591171265},{"id":"https://openalex.org/C2779921676","wikidata":"https://www.wikidata.org/wiki/Q6760434","display_name":"Marginal zone","level":4,"score":0.4494721591472626},{"id":"https://openalex.org/C2779720271","wikidata":"https://www.wikidata.org/wiki/Q179422","display_name":"Lymph","level":2,"score":0.4478797912597656},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.44425299763679504},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.4426245093345642},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3871813118457794},{"id":"https://openalex.org/C2778453870","wikidata":"https://www.wikidata.org/wiki/Q188930","display_name":"B cell","level":3,"score":0.38607922196388245},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37721264362335205},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.3229389190673828},{"id":"https://openalex.org/C16224149","wikidata":"https://www.wikidata.org/wiki/Q187637","display_name":"Cell adhesion molecule","level":2,"score":0.13311073184013367},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.11604323983192444}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-012466044-1/50516-0","doi":"https://doi.org/10.1016/b978-012466044-1/50516-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-012466044-1/50516-0","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Gene Knockout FactsBook","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8199999928474426}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1569057989","https://openalex.org/W1592460255","https://openalex.org/W1594462828","https://openalex.org/W1768210657","https://openalex.org/W1966684157","https://openalex.org/W1997349521","https://openalex.org/W2062242135","https://openalex.org/W2088325902","https://openalex.org/W2128256270","https://openalex.org/W2163571135"],"related_works":["https://openalex.org/W1997349521","https://openalex.org/W1768210657","https://openalex.org/W2163571135","https://openalex.org/W1569057989","https://openalex.org/W1966684157","https://openalex.org/W1501685982","https://openalex.org/W7099404316","https://openalex.org/W2156697769","https://openalex.org/W2148792638","https://openalex.org/W2006170925"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2022-05-12T00:00:00"}
