{"id":"https://openalex.org/W4243662533","doi":"https://doi.org/10.1002/bip.22293","title":"Frameshifting dynamics","display_name":"Frameshifting dynamics","publication_year":2013,"publication_date":"2013-05-31","ids":{"openalex":"https://openalex.org/W4243662533","doi":"https://doi.org/10.1002/bip.22293","pmid":"https://pubmed.ncbi.nlm.nih.gov/23722586","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4011568"},"language":"en","primary_location":{"id":"doi:10.1002/bip.22293","doi":"https://doi.org/10.1002/bip.22293","is_oa":false,"landing_page_url":"https://doi.org/10.1002/bip.22293","pdf_url":null,"source":{"id":"https://openalex.org/S56808608","display_name":"Biopolymers","issn_l":"0006-3525","issn":["0006-3525","1097-0282"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biopolymers","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4011568","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111538822","display_name":"Ignacio Tinoco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ignacio Tinoco","raw_affiliation_strings":["Department of Chemistry, University of California, Berkeley, Berkeley, CA, 94720-1460"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of California, Berkeley, Berkeley, CA, 94720-1460","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037727830","display_name":"Hee\u2010Kyung Kim","orcid":"https://orcid.org/0000-0003-2103-4835","observed_orcids":["https://orcid.org/0000-0003-2103-4835"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hee\u2010Kyung Kim","raw_affiliation_strings":["Department of Chemistry, University of California, Berkeley, Berkeley, CA, 94720-1460"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of California, Berkeley, Berkeley, CA, 94720-1460","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014664746","display_name":"Shannon Yan","orcid":"https://orcid.org/0000-0001-7994-9427","observed_orcids":["https://orcid.org/0000-0001-7994-9427"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shannon Yan","raw_affiliation_strings":["Department of Chemistry, University of California, Berkeley, Berkeley, CA, 94720-1460"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of California, Berkeley, Berkeley, CA, 94720-1460","institution_ids":["https://openalex.org/I95457486"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111538822"],"corresponding_institution_ids":["https://openalex.org/I95457486"],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":null,"fwci":0.3445,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.30350353,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"99","issue":"12","first_page":"1147","last_page":"1166"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ribosomal-frameshifting","display_name":"ribosomal frameshifting","score":0.8560000061988831},{"id":"https://openalex.org/keywords/ribosome-dynamics","display_name":"ribosome dynamics","score":0.6320000290870667},{"id":"https://openalex.org/keywords/ribosome-structure","display_name":"ribosome structure","score":0.8519999980926514},{"id":"https://openalex.org/keywords/mrna-translation","display_name":"mRNA translation","score":0.5929999947547913},{"id":"https://openalex.org/keywords/viral-rna","display_name":"viral RNA","score":0.7250000238418579},{"id":"https://openalex.org/keywords/single-molecule-methods","display_name":"single-molecule methods","score":0.6129999756813049},{"id":"https://openalex.org/keywords/optical-tweezers","display_name":"optical tweezers","score":0.9890000224113464},{"id":"https://openalex.org/keywords/fluorescence-resonance-energy-transfer","display_name":"fluorescence resonance energy transfer","score":0.8289999961853027}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8770831823348999},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.6171126961708069},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3692624568939209},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.07264623045921326},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012270","descriptor_name":"Ribosomes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012367","descriptor_name":"RNA, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018965","descriptor_name":"Frameshifting, Ribosomal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1002/bip.22293","doi":"https://doi.org/10.1002/bip.22293","is_oa":false,"landing_page_url":"https://doi.org/10.1002/bip.22293","pdf_url":null,"source":{"id":"https://openalex.org/S56808608","display_name":"Biopolymers","issn_l":"0006-3525","issn":["0006-3525","1097-0282"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biopolymers","raw_type":"journal-article"},{"id":"pmid:23722586","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23722586","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biopolymers","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4011568","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4011568","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biopolymers","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4011568","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4011568","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biopolymers","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3676917958","display_name":null,"funder_award_id":"GM10840","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G3918681150","display_name":"STRUCTURE/FUNCTION OF NUCLEIC ACIDS","funder_award_id":"R37GM010840","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G444127963","display_name":"Structure and Function of Nucleic Acids","funder_award_id":"R01GM010840","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":102,"referenced_works":["https://openalex.org/W1551583539","https://openalex.org/W1970107043","https://openalex.org/W1971018806","https://openalex.org/W1974681176","https://openalex.org/W1977472875","https://openalex.org/W1978427706","https://openalex.org/W1980412333","https://openalex.org/W1980418007","https://openalex.org/W1984316935","https://openalex.org/W1986240764","https://openalex.org/W1986381105","https://openalex.org/W1987224264","https://openalex.org/W1989071971","https://openalex.org/W1990879059","https://openalex.org/W1992657741","https://openalex.org/W1999047662","https://openalex.org/W1999249940","https://openalex.org/W2000798648","https://openalex.org/W2004646850","https://openalex.org/W2007789562","https://openalex.org/W2010400841","https://openalex.org/W2010425539","https://openalex.org/W2015365987","https://openalex.org/W2019054377","https://openalex.org/W2021958628","https://openalex.org/W2022754910","https://openalex.org/W2024858227","https://openalex.org/W2031536080","https://openalex.org/W2034108516","https://openalex.org/W2035667407","https://openalex.org/W2038354483","https://openalex.org/W2038864352","https://openalex.org/W2039553437","https://openalex.org/W2040204840","https://openalex.org/W2040843640","https://openalex.org/W2042528449","https://openalex.org/W2042974448","https://openalex.org/W2045938444","https://openalex.org/W2047405192","https://openalex.org/W2047706687","https://openalex.org/W2050375095","https://openalex.org/W2051937183","https://openalex.org/W2054511300","https://openalex.org/W2056781801","https://openalex.org/W2057756542","https://openalex.org/W2059444842","https://openalex.org/W2062986404","https://openalex.org/W2068577220","https://openalex.org/W2068970210","https://openalex.org/W2070936740","https://openalex.org/W2073149987","https://openalex.org/W2073504319","https://openalex.org/W2075024467","https://openalex.org/W2075685878","https://openalex.org/W2076034830","https://openalex.org/W2078286476","https://openalex.org/W2080597338","https://openalex.org/W2080720176","https://openalex.org/W2083147729","https://openalex.org/W2087217881","https://openalex.org/W2087646044","https://openalex.org/W2088721967","https://openalex.org/W2089471930","https://openalex.org/W2092035637","https://openalex.org/W2092974248","https://openalex.org/W2093471887","https://openalex.org/W2094811968","https://openalex.org/W2095598198","https://openalex.org/W2096977502","https://openalex.org/W2099029809","https://openalex.org/W2102383695","https://openalex.org/W2105698649","https://openalex.org/W2110035826","https://openalex.org/W2110274742","https://openalex.org/W2117430673","https://openalex.org/W2118890133","https://openalex.org/W2122996035","https://openalex.org/W2124081058","https://openalex.org/W2127380975","https://openalex.org/W2131446325","https://openalex.org/W2133788397","https://openalex.org/W2134073121","https://openalex.org/W2134410571","https://openalex.org/W2138171929","https://openalex.org/W2139736241","https://openalex.org/W2145067132","https://openalex.org/W2145234478","https://openalex.org/W2146912125","https://openalex.org/W2149407899","https://openalex.org/W2152482656","https://openalex.org/W2153540299","https://openalex.org/W2156483862","https://openalex.org/W2160445124","https://openalex.org/W2160615413","https://openalex.org/W2163231470","https://openalex.org/W2164309680","https://openalex.org/W2165048399","https://openalex.org/W2166053360","https://openalex.org/W2170708210","https://openalex.org/W2171205452","https://openalex.org/W2325916690","https://openalex.org/W2328746876"],"related_works":["https://openalex.org/W2033946310","https://openalex.org/W2998219762","https://openalex.org/W2036452203","https://openalex.org/W3005000518","https://openalex.org/W4404325272","https://openalex.org/W4319880842","https://openalex.org/W2294137743","https://openalex.org/W4306698947","https://openalex.org/W3172142859","https://openalex.org/W1278468206"],"abstract_inverted_index":{"Translation":[0],"of":[1,36,66,72],"messenger":[2,51],"RNA":[3,60],"by":[4,104,109],"a":[5,11,19],"ribosome":[6,94],"occurs":[7],"three":[8],"nucleotides":[9,24],"at":[10],"time":[12],"from":[13,42],"start":[14],"signal":[15],"to":[16,62,69,100],"stop.":[17],"However,":[18],"frameshift":[20],"means":[21],"that":[22,77],"some":[23,29,50],"are":[25,30,88],"read":[26],"twice":[27],"or":[28],"skipped,":[31],"and":[32,96,108,116],"the":[33,43,46,70,73],"following":[34],"sequence":[35,44],"amino":[37],"acids":[38],"is":[39,57],"completely":[40],"different":[41],"in":[45,98],"original":[47],"frame.":[48],"In":[49],"RNAs,":[52,55],"including":[53],"viral":[54],"frameshifting":[56,79,101],"programmed":[58],"with":[59],"signals":[61],"produce":[63],"specific":[64],"ratios":[65],"proteins":[67],"vital":[68],"replication":[71],"organism.":[74],"The":[75],"mechanisms":[76],"cause":[78],"have":[80],"been":[81],"studied":[82],"for":[83],"many":[84],"years,":[85],"but":[86],"there":[87],"no":[89],"definitive":[90],"conclusions.":[91],"We":[92],"review":[93],"structure":[95],"dynamics":[97,102],"relation":[99],"provided":[103],"classical":[105],"ensemble":[106],"studies,":[107],"new":[110],"single-molecule":[111],"methods":[112],"using":[113],"optical":[114],"tweezers":[115],"FRET.":[117]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-05-12T00:00:00"}