{"id":"https://openalex.org/W4243222732","doi":"https://doi.org/10.1097/00006534-200212000-00009","title":"Wet Wound Healing","display_name":"Wet Wound Healing","publication_year":2002,"publication_date":"2002-12-01","ids":{"openalex":"https://openalex.org/W4243222732","doi":"https://doi.org/10.1097/00006534-200212000-00009","mag":"2025458027","pmid":"https://pubmed.ncbi.nlm.nih.gov/12447049"},"language":"en","primary_location":{"id":"doi:10.1097/00006534-200212000-00009","doi":"https://doi.org/10.1097/00006534-200212000-00009","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00006534-200212000-00009","pdf_url":null,"source":{"id":"https://openalex.org/S100736837","display_name":"Plastic & Reconstructive Surgery","issn_l":"0032-1052","issn":["0032-1052","1076-5751","1529-4242"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and Reconstructive Surgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010933799","display_name":"Jan Jeroen Vranckx","orcid":"https://orcid.org/0000-0002-0920-8620","observed_orcids":["https://orcid.org/0000-0002-0920-8620"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jan J. Vranckx","raw_affiliation_strings":["the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","revised February 7, 2002","the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"revised February 7, 2002","institution_ids":[]},{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103381506","display_name":"Jarom\u00edr Sl\u00e1ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jaromir Slama","raw_affiliation_strings":["the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","revised February 7, 2002","the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"revised February 7, 2002","institution_ids":[]},{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070013582","display_name":"Stefan Preuss","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stefan Preuss","raw_affiliation_strings":["the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","revised February 7, 2002","the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"revised February 7, 2002","institution_ids":[]},{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072850885","display_name":"Norvin Perez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Norvin Perez","raw_affiliation_strings":["the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","revised February 7, 2002","the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"revised February 7, 2002","institution_ids":[]},{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051621973","display_name":"Tor Svensj","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tor Svensj??","raw_affiliation_strings":["revised February 7, 2002","the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"revised February 7, 2002","institution_ids":[]},{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001378844","display_name":"Scott Visovatti","orcid":"https://orcid.org/0000-0002-4595-1657","observed_orcids":["https://orcid.org/0000-0002-4595-1657"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott Visovatti","raw_affiliation_strings":["the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","revised February 7, 2002","the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"revised February 7, 2002","institution_ids":[]},{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074117670","display_name":"Karl H. Breuing","orcid":"https://orcid.org/0000-0002-2344-2552","observed_orcids":["https://orcid.org/0000-0002-2344-2552"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karl Breuing","raw_affiliation_strings":["the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","revised February 7, 2002","the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"revised February 7, 2002","institution_ids":[]},{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Richard Bartlett","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Bartlett","raw_affiliation_strings":["the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","revised February 7, 2002","the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"revised February 7, 2002","institution_ids":[]},{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051425107","display_name":"Julian Joseph Pribaz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julian Pribaz","raw_affiliation_strings":["the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","revised February 7, 2002","the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"revised February 7, 2002","institution_ids":[]},{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010708959","display_name":"Denton D. Weiss","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Denton Weiss","raw_affiliation_strings":["the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","revised February 7, 2002","the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"revised February 7, 2002","institution_ids":[]},{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007523102","display_name":"Elof K. Eriksson","orcid":"https://orcid.org/0000-0003-2514-1646","observed_orcids":["https://orcid.org/0000-0003-2514-1646"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elof Eriksson","raw_affiliation_strings":["the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","revised February 7, 2002","the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001; revised February 7, 2002","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"revised February 7, 2002","institution_ids":[]},{"raw_affiliation_string":"the Laboratory of Tissue Repair and Gene Transfer, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School. Received for publication September 7, 2001","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.7171,"has_fulltext":false,"cited_by_count":55,"citation_normalized_percentile":{"value":0.88646288,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"110","issue":"7","first_page":"1680","last_page":"1687"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11080","display_name":"Surgical site infection prevention","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11227","display_name":"Diabetic Foot Ulcer Assessment and Management","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wound-infection","display_name":"wound infection","score":0.6129999756813049},{"id":"https://openalex.org/keywords/topical-antibiotic-delivery","display_name":"topical antibiotic delivery","score":0.8090000152587891},{"id":"https://openalex.org/keywords/vancomycin","display_name":"vancomycin","score":0.6899999976158142},{"id":"https://openalex.org/keywords/gentamicin","display_name":"gentamicin","score":1.0},{"id":"https://openalex.org/keywords/artificial-joints","display_name":"artificial joints","score":0.7419999837875366},{"id":"https://openalex.org/keywords/delayed-skin-grafting","display_name":"delayed skin grafting","score":0.6660000085830688},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.5189999938011169},{"id":"https://openalex.org/keywords/corticosteroid-use","display_name":"corticosteroid use","score":0.796999990940094}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9624700546264648},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.6749054193496704},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.6713421940803528},{"id":"https://openalex.org/C2777397205","wikidata":"https://www.wikidata.org/wiki/Q275792","display_name":"Saline","level":2,"score":0.63139408826828},{"id":"https://openalex.org/C2993873987","wikidata":"https://www.wikidata.org/wiki/Q184753","display_name":"Wound closure","level":3,"score":0.531627357006073},{"id":"https://openalex.org/C2777750529","wikidata":"https://www.wikidata.org/wiki/Q1591440","display_name":"Skin grafting","level":2,"score":0.5249162316322327},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.4162371754646301},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.2504345178604126},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001458","descriptor_name":"Bandages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007871","descriptor_name":"Leg Ulcer","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013530","descriptor_name":"Surgical Wound Infection","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1097/00006534-200212000-00009","doi":"https://doi.org/10.1097/00006534-200212000-00009","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00006534-200212000-00009","pdf_url":null,"source":{"id":"https://openalex.org/S100736837","display_name":"Plastic & Reconstructive Surgery","issn_l":"0032-1052","issn":["0032-1052","1076-5751","1529-4242"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and Reconstructive Surgery","raw_type":"journal-article"},{"id":"pmid:12447049","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12447049","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and reconstructive surgery","raw_type":"Journal Article"},{"id":"mag:2025458027","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12447049","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9789000153541565}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.800000011920929}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1971934781","https://openalex.org/W1994288226","https://openalex.org/W2001297140","https://openalex.org/W2009794271","https://openalex.org/W2015475504","https://openalex.org/W2016707883","https://openalex.org/W2026438861","https://openalex.org/W2054636263","https://openalex.org/W2064153544","https://openalex.org/W2068996143","https://openalex.org/W2072026431","https://openalex.org/W2081583807","https://openalex.org/W2151296455","https://openalex.org/W2170312757","https://openalex.org/W4251877104","https://openalex.org/W4294308241"],"related_works":["https://openalex.org/W2015475504","https://openalex.org/W2137257492","https://openalex.org/W2013605899","https://openalex.org/W2418314993","https://openalex.org/W2407375724","https://openalex.org/W2315143754","https://openalex.org/W87304059","https://openalex.org/W2418556780","https://openalex.org/W4302407150","https://openalex.org/W2151953344"],"abstract_inverted_index":{"Wound":[0],"treatment":[1,228,334],"in":[2,22,25,42,46,111,186,291,317,332],"a":[3,16,99,117,189,201,248,260,328],"flexible":[4],"transparent":[5],"chamber":[6,44,68,119,185,203,227,244,320,326],"attached":[7],"to":[8,29,60,72,77,133,279,295],"the":[9,12,35,37,43,61,64,73,78,94,103,183,205,210,225,233,274,298,311,318,324,333],"perimeter":[10],"of":[11,102,108,154,209,293,310,335],"wound":[13,62,67,74,95,118,184,202,206,319,325],"and":[14,27,51,54,97,122,129,140,173,215,229,255,286],"containing":[15,120],"liquid":[17,38],"has":[18],"been":[19],"extensively":[20],"tested":[21],"preclinical":[23],"experiments":[24],"pigs":[26],"found":[28],"offer":[30],"several":[31],"advantages.":[32],"It":[33],"protects":[34],"wound;":[36],"medium":[39],"or":[40,76,135,144,168,193,308],"saline":[41,121],"provides":[45,327],"vivo":[47],"tissue":[48],"culture-like":[49],"conditions;":[50],"antibiotics,":[52],"analgesics,":[53],"various":[55],"molecules":[56],"can":[57,88],"be":[58,289],"delivered":[59],"through":[63],"chamber.":[65],"The":[66],"causes":[69],"no":[70],"injury":[71],"itself":[75],"surrounding":[79],"intact":[80],"skin.":[81],"Topical":[82],"delivery":[83,264],"of,":[84],"for":[85,164,188,276],"instance,":[86],"antibiotics":[87],"provide":[89],"very":[90],"high":[91],"concentrations":[92,292],"at":[93,259],"site":[96],"with":[98,116,138,182,200],"favorable":[100],"direction":[101],"concentration":[104,314],"gradient.":[105],"A":[106],"series":[107],"28":[109],"wounds":[110,148,211,217,235],"20":[112,306],"patients":[113,125,160,175,179],"were":[114,156,161,180],"treated":[115,181,199],"antibiotics.":[123],"Most":[124,178],"had":[126,130,149,176,247],"significant":[127],"comorbidity":[128],"not":[131,238,253],"responded":[132],"conservative":[134,222],"surgical":[136],"management":[137,223],"d\u00e9bridement":[139],"delayed":[141,190],"primary":[142],"closure":[143],"skin":[145,191,249],"grafts.":[146],"Six":[147],"foreign":[150],"bodies":[151],"present;":[152],"four":[153,174],"these":[155],"joint":[157],"prostheses.":[158],"Seven":[159],"on":[162],"corticosteroids":[163],"rheumatoid":[165],"arthritis,":[166],"lupus,":[167],"chronic":[169],"obstructive":[170],"pulmonary":[171],"disease,":[172],"diabetes.":[177],"preparation":[187],"graft":[192,250],"flap":[194],"procedure,":[195],"but":[196],"one":[197,240,246,256,268],"was":[198,265,315],"until":[204],"healed.":[207],"Twenty-five":[208],"(89":[212],"percent)":[213,219],"healed,":[214],"five":[216],"(18":[218],"required":[220,257],"additional":[221,243],"after":[224,242,304],"initial":[226],"grafting":[230],"procedure.":[231],"Of":[232],"three":[234],"that":[236,251],"did":[237,252],"heal,":[239],"healed":[241],"treatment,":[245],"take,":[254],"reamputation":[258],"higher":[261],"level.":[262],"Antibiotic":[263],"less":[266],"than":[267],"intravenous":[269],"dose":[270],"daily,":[271],"which":[272],"avoided":[273],"potential":[275],"systemic":[277],"absorption":[278],"toxic":[280],"levels.":[281],"Antibiotics":[282],"such":[283],"as":[284],"vancomycin":[285],"gentamicin":[287],"could":[288],"used":[290],"up":[294],"10,000":[296],"times":[297],"minimal":[299],"inhibitory":[300],"concentration.":[301],"Forty-eight":[302],"hours":[303],"application,":[305],"percent":[307],"more":[309],"original":[312],"antibiotic":[313],"present":[316],"fluid.":[321],"In":[322],"conclusion,":[323],"safe,":[329],"powerful":[330],"tool":[331],"difficult":[336],"infected":[337],"wounds.":[338]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-05-12T00:00:00"}