{"id":"https://openalex.org/W4242979798","doi":"https://doi.org/10.3410/f.727253320.793529105","title":"Faculty Opinions recommendation of IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice.","display_name":"Faculty Opinions recommendation of IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice.","publication_year":2017,"publication_date":"2017-02-27","ids":{"openalex":"https://openalex.org/W4242979798","doi":"https://doi.org/10.3410/f.727253320.793529105"},"language":"en","primary_location":{"id":"doi:10.3410/f.727253320.793529105","doi":"https://doi.org/10.3410/f.727253320.793529105","is_oa":false,"landing_page_url":"https://doi.org/10.3410/f.727253320.793529105","pdf_url":null,"source":{"id":"https://openalex.org/S4363604054","display_name":"Faculty Opinions \u2013 Post-Publication Peer Review of the Biomedical Literature","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Faculty Opinions \u2013 Post-Publication Peer Review of the Biomedical Literature","raw_type":"dataset"},"volume":null,"type":"peer-review","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027470095","display_name":"David J. Rawlings","orcid":"https://orcid.org/0000-0002-0810-1776","observed_orcids":["https://orcid.org/0000-0002-0810-1776","https://orcid.org/0000-0003-4370-4772"]},"institutions":[{"id":"https://openalex.org/I1295499534","display_name":"Seattle Children's Hospital","ror":"https://ror.org/01njes783","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534"]},{"id":"https://openalex.org/I4405262941","display_name":"Seattle Children's Research Institute","ror":"https://ror.org/00cz0md82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534","https://openalex.org/I4405262941"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Rawlings","raw_affiliation_strings":["Department of Immunology, Seattle Children's Hospital Research Institute, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Seattle Children's Hospital Research Institute, USA","institution_ids":["https://openalex.org/I1295499534","https://openalex.org/I4405262941"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032951559","display_name":"Eric J. Allenspach","orcid":"https://orcid.org/0000-0001-7346-5835","observed_orcids":["https://orcid.org/0000-0001-7346-5835"]},"institutions":[{"id":"https://openalex.org/I1295499534","display_name":"Seattle Children's Hospital","ror":"https://ror.org/01njes783","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534"]},{"id":"https://openalex.org/I4405262941","display_name":"Seattle Children's Research Institute","ror":"https://ror.org/00cz0md82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534","https://openalex.org/I4405262941"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric Allenspach","raw_affiliation_strings":["Department of Immunology, Seattle Children's Hospital Research Institute, USA"],"raw_orcid":"https://orcid.org/0000-0001-7346-5835","affiliations":[{"raw_affiliation_string":"Department of Immunology, Seattle Children's Hospital Research Institute, USA","institution_ids":["https://openalex.org/I1295499534","https://openalex.org/I4405262941"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.00559999980032444,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microbiota","display_name":"microbiota","score":0.6919999718666077},{"id":"https://openalex.org/keywords/mucosa-associated-lymphoid-tissue","display_name":"mucosa-associated lymphoid tissue","score":0.9890000224113464},{"id":"https://openalex.org/keywords/immunoglobulin-isotype-switching","display_name":"immunoglobulin isotype switching","score":0.6990000009536743},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.7160000205039978},{"id":"https://openalex.org/keywords/b-cells","display_name":"B cells","score":0.49900001287460327},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.38199999928474426}],"concepts":[{"id":"https://openalex.org/C48010095","wikidata":"https://www.wikidata.org/wiki/Q79447","display_name":"Immunoglobulin D","level":4,"score":0.7491205334663391},{"id":"https://openalex.org/C181152851","wikidata":"https://www.wikidata.org/wiki/Q712604","display_name":"Lymphatic system","level":2,"score":0.6317249536514282},{"id":"https://openalex.org/C2777212361","wikidata":"https://www.wikidata.org/wiki/Q5127848","display_name":"Class (philosophy)","level":2,"score":0.5104933977127075},{"id":"https://openalex.org/C2779088137","wikidata":"https://www.wikidata.org/wiki/Q854346","display_name":"Gut-associated lymphoid tissue","level":3,"score":0.4492800831794739},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4248071610927582},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40870675444602966},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3582598567008972},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33600160479545593},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.15838155150413513},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.14628973603248596},{"id":"https://openalex.org/C2778453870","wikidata":"https://www.wikidata.org/wiki/Q188930","display_name":"B cell","level":3,"score":0.07952061295509338},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.05518534779548645}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3410/f.727253320.793529105","doi":"https://doi.org/10.3410/f.727253320.793529105","is_oa":false,"landing_page_url":"https://doi.org/10.3410/f.727253320.793529105","pdf_url":null,"source":{"id":"https://openalex.org/S4363604054","display_name":"Faculty Opinions \u2013 Post-Publication Peer Review of the Biomedical Literature","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Faculty Opinions \u2013 Post-Publication Peer Review of the Biomedical Literature","raw_type":"dataset"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4000000059604645}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W45930941","https://openalex.org/W2580456492","https://openalex.org/W6906631098"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2022-05-12T00:00:00"}