{"id":"https://openalex.org/W4242884267","doi":"https://doi.org/10.1016/b978-012466044-1/50471-3","title":"Pax 7","display_name":"Pax 7","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W4242884267","doi":"https://doi.org/10.1016/b978-012466044-1/50471-3"},"language":"en","primary_location":{"id":"doi:10.1016/b978-012466044-1/50471-3","doi":"https://doi.org/10.1016/b978-012466044-1/50471-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-012466044-1/50471-3","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Gene Knockout FactsBook","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W564011763","display_name":"The Gene Knockout FactsBook"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000800493","display_name":"Tak W. Mak","orcid":"https://orcid.org/0000-0001-6766-861X","observed_orcids":["https://orcid.org/0000-0001-6766-861X","https://orcid.org/0000-0002-0459-4112"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2802654988","display_name":"Princess Margaret Cancer Centre","ror":"https://ror.org/03zayce58","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2802654988"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Tak W. Mak","raw_affiliation_strings":["Amgen Institute, Department of Medicial Biophysics, University of Toronto, Toronto, Canada","Department of Immunology, University of Toronto, Toronto, Canada","Editor-in-chief Ontario Cancer Institute/Princess Margaret Hospital, University of Toronto, Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amgen Institute, Department of Medicial Biophysics, University of Toronto, Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Department of Immunology, University of Toronto, Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Editor-in-chief Ontario Cancer Institute/Princess Margaret Hospital, University of Toronto, Toronto, Canada","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I2802654988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059310975","display_name":"Josef Martin Penninger","orcid":"https://orcid.org/0000-0002-8194-3777","observed_orcids":["https://orcid.org/0000-0002-8194-3777"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2802654988","display_name":"Princess Margaret Cancer Centre","ror":"https://ror.org/03zayce58","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2802654988"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Josef Penninger","raw_affiliation_strings":["Amgen Institute, Department of Medical Biophysics, University of Toronto, Canada","Department of Immunology, University of Toronto, Toronto, Canada","Ontario Cancer Institute/Princess Margaret Hospital, University of Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amgen Institute, Department of Medical Biophysics, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Department of Immunology, University of Toronto, Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Ontario Cancer Institute/Princess Margaret Hospital, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I2802654988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111715744","display_name":"John Roder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1291836623","display_name":"Mount Sinai Hospital","ror":"https://ror.org/05deks119","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1291836623","https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I210557978","display_name":"Lunenfeld-Tanenbaum Research Institute","ror":"https://ror.org/01s5axj25","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1291836623","https://openalex.org/I210557978","https://openalex.org/I4210130843"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"John Roder","raw_affiliation_strings":["Department of Immunology, University of Toronto, Canada","Department of Molecular and Medical Genetics, University of Toronto, Canada","Program in Development and Fetal Health, Samuel Lunenfeld. Research Institute, Mount Sinai Hospital, University of Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Department of Molecular and Medical Genetics, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Program in Development and Fetal Health, Samuel Lunenfeld. Research Institute, Mount Sinai Hospital, University of Toronto, Canada","institution_ids":["https://openalex.org/I1291836623","https://openalex.org/I185261750","https://openalex.org/I210557978"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011985445","display_name":"Janet Rossant","orcid":"https://orcid.org/0000-0002-3731-5466","observed_orcids":["https://orcid.org/0000-0002-3731-5466"]},"institutions":[{"id":"https://openalex.org/I1291836623","display_name":"Mount Sinai Hospital","ror":"https://ror.org/05deks119","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1291836623","https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I210557978","display_name":"Lunenfeld-Tanenbaum Research Institute","ror":"https://ror.org/01s5axj25","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1291836623","https://openalex.org/I210557978","https://openalex.org/I4210130843"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Janet Rossant","raw_affiliation_strings":["Department of Molecular and Medical Genetics, University of Toronto, Canada","Department of Obstetrics/Gynaecology, University of Toronto, Canada","Program in Development and Fetal Health, Samuel Lunenfeld Research Institute, Mount Sinai Hospital University of Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Medical Genetics, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Department of Obstetrics/Gynaecology, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Program in Development and Fetal Health, Samuel Lunenfeld Research Institute, Mount Sinai Hospital University of Toronto, Canada","institution_ids":["https://openalex.org/I1291836623","https://openalex.org/I185261750","https://openalex.org/I210557978"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023514711","display_name":"Mary E. Saunders","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mary Saunders","raw_affiliation_strings":["Senior Scientist/Scientific Editor Amgen Institute, Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Senior Scientist/Scientific Editor Amgen Institute, Toronto, Canada","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.48851685,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"855","last_page":"855"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9639000296592712,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9639000296592712,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11374","display_name":"Cleft Lip and Palate Research","score":0.00989999994635582,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11679","display_name":"Craniofacial Disorders and Treatments","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pax7","display_name":"Pax7","score":0.9670000076293945},{"id":"https://openalex.org/keywords/pax3","display_name":"Pax3","score":0.628000020980835},{"id":"https://openalex.org/keywords/heterozygous-mice","display_name":"heterozygous mice","score":0.8330000042915344},{"id":"https://openalex.org/keywords/homozygous-lethality","display_name":"homozygous lethality","score":0.7360000014305115},{"id":"https://openalex.org/keywords/neural-crest-derivatives","display_name":"neural crest derivatives","score":0.7910000085830688},{"id":"https://openalex.org/keywords/cranial-neural-crest","display_name":"cranial neural crest","score":0.7689999938011169},{"id":"https://openalex.org/keywords/nasal-capsule","display_name":"nasal capsule","score":0.6039999723434448},{"id":"https://openalex.org/keywords/serous-glands","display_name":"serous glands","score":0.8429999947547913},{"id":"https://openalex.org/keywords/lacrimal-bone","display_name":"lacrimal bone","score":0.8659999966621399},{"id":"https://openalex.org/keywords/maxilla","display_name":"maxilla","score":0.8420000076293945},{"id":"https://openalex.org/keywords/brain-vesicles","display_name":"brain vesicles","score":0.6629999876022339},{"id":"https://openalex.org/keywords/embryonic-development","display_name":"embryonic development","score":0.628000020980835}],"concepts":[{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.6719075441360474},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5312167406082153},{"id":"https://openalex.org/C552161191","wikidata":"https://www.wikidata.org/wiki/Q185080","display_name":"Midbrain","level":3,"score":0.5103678107261658},{"id":"https://openalex.org/C126749454","wikidata":"https://www.wikidata.org/wiki/Q1348455","display_name":"Neural crest","level":3,"score":0.4463196098804474},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.20517951250076294},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.161164790391922},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15291327238082886},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0855674147605896}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-012466044-1/50471-3","doi":"https://doi.org/10.1016/b978-012466044-1/50471-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-012466044-1/50471-3","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Gene Knockout FactsBook","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W1892875901"],"related_works":["https://openalex.org/W1892875901","https://openalex.org/W4280648760","https://openalex.org/W2156170081","https://openalex.org/W1983203915","https://openalex.org/W2106433235","https://openalex.org/W1999894493","https://openalex.org/W2154234024","https://openalex.org/W1651589930","https://openalex.org/W2231780206","https://openalex.org/W2093909540"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2022-05-12T00:00:00"}
