{"id":"https://openalex.org/W4242802574","doi":"https://doi.org/10.1109/iembs.2006.4397442","title":"Ultrasound Accelerated Bone Tissue Engineering Monitored with Magnetic Resonance Microscopy","display_name":"Ultrasound Accelerated Bone Tissue Engineering Monitored with Magnetic Resonance Microscopy","publication_year":2006,"publication_date":"2006-08-01","ids":{"openalex":"https://openalex.org/W4242802574","doi":"https://doi.org/10.1109/iembs.2006.4397442"},"language":"en","primary_location":{"id":"doi:10.1109/iembs.2006.4397442","doi":"https://doi.org/10.1109/iembs.2006.4397442","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2006.4397442","pdf_url":null,"source":{"id":"https://openalex.org/S4210217943","display_name":"Conference proceedings","issn_l":"1557-170X","issn":["1557-170X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2006 International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031900911","display_name":"Jessy J. Moinnes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessy J. Moinnes","raw_affiliation_strings":["University of Illinois, Chicago, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Illinois, Chicago, Chicago, IL, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039802529","display_name":"Neelima Vidula","orcid":"https://orcid.org/0000-0002-5963-7052","observed_orcids":["https://orcid.org/0000-0002-5963-7052"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neelima Vidula","raw_affiliation_strings":["Department of Bioengineering, University of Illinois, Chicago, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, University of Illinois, Chicago, Chicago, IL, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053141905","display_name":"Nadia Halim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nadia Halim","raw_affiliation_strings":["Department of Bioengineering, University of Illinois, Chicago, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, University of Illinois, Chicago, Chicago, IL, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088671272","display_name":"Shadi F. Othman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shadi F. Othman","raw_affiliation_strings":["Department of Bioengineering, University of Illinois, Chicago, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, University of Illinois, Chicago, Chicago, IL, USA","institution_ids":["https://openalex.org/I39422238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I39422238"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.45298347,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11068","display_name":"Tendon Structure and Treatment","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bone-tissue-engineering","display_name":"bone tissue engineering","score":0.8240000009536743},{"id":"https://openalex.org/keywords/low-intensity-ultrasound","display_name":"low-intensity ultrasound","score":0.9259999990463257},{"id":"https://openalex.org/keywords/ultrasound-stimulation","display_name":"ultrasound stimulation","score":0.7110000252723694},{"id":"https://openalex.org/keywords/bone-formation","display_name":"bone formation","score":0.9010000228881836},{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.9269999861717224},{"id":"https://openalex.org/keywords/magnetic-resonance-microscopy","display_name":"magnetic resonance microscopy","score":0.9580000042915344},{"id":"https://openalex.org/keywords/t2-relaxation-time","display_name":"T2 relaxation time","score":0.9459999799728394},{"id":"https://openalex.org/keywords/non-invasive-monitoring","display_name":"non-invasive monitoring","score":0.9129999876022339},{"id":"https://openalex.org/keywords/bone-regeneration","display_name":"bone regeneration","score":0.5350000262260437}],"concepts":[{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.6596812009811401},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.6216633915901184},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.6087691783905029},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.5705991387367249},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5687723159790039},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.5311362147331238},{"id":"https://openalex.org/C8337478","wikidata":"https://www.wikidata.org/wiki/Q1777289","display_name":"Bone healing","level":2,"score":0.5081212520599365},{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.4267967939376831},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38569051027297974},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.36502909660339355},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24415123462677002},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.22275841236114502},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.21637305617332458},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15139254927635193},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.13247615098953247},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/iembs.2006.4397442","doi":"https://doi.org/10.1109/iembs.2006.4397442","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2006.4397442","pdf_url":null,"source":{"id":"https://openalex.org/S4210217943","display_name":"Conference proceedings","issn_l":"1557-170X","issn":["1557-170X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2006 International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6000000238418579}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1981035770","https://openalex.org/W2019574686","https://openalex.org/W2589508205","https://openalex.org/W2073721125","https://openalex.org/W2040200135","https://openalex.org/W2573646367","https://openalex.org/W2294369453","https://openalex.org/W2106364026","https://openalex.org/W2382014342","https://openalex.org/W1628263342"],"abstract_inverted_index":{"Tissue":[0],"engineering":[1],"has":[2,46],"the":[3,36,75,79,91,96,122,139],"potential":[4],"to":[5,23,29,49],"treat":[6],"bone":[7,11,27,40,51,59],"loss,":[8],"but":[9],"current":[10],"restoration":[12],"methods,":[13],"including":[14],"osteogenesis":[15,132],"from":[16],"mesenchymal":[17],"stem":[18],"cells":[19],"(MSCs),":[20],"require":[21],"three":[22],"four":[24],"weeks":[25],"for":[26,116,135],"formation":[28,37],"occur.":[30],"In":[31],"this":[32],"study,":[33],"we":[34],"stimulated":[35],"of":[38,57,77,94,143],"engineered":[39,58,80,137],"tissue":[41,136],"with":[42,121],"low-intensity":[43],"ultrasound,":[44],"which":[45,144],"been":[47],"proven":[48],"accelerate":[50,131],"healing":[52],"in":[53,133],"vivo.":[54],"One":[55],"group":[56],"constructs":[60,81,97,118],"received":[61],"ultrasound":[62,129],"stimulation":[63],"20":[64],"minutes":[65],"per":[66],"day":[67],"over":[68],"a":[69,101],"3-week":[70],"growth":[71,76,140],"period.":[72],"We":[73],"monitored":[74,147],"all":[78,95,117],"quantitatively":[82],"and":[83,111,119,141],"noninvasively":[84],"using":[85,104,148],"magnetic":[86],"resonance":[87],"microscopy":[88],"(MRM),":[89],"where":[90],"T2relaxation":[92],"times":[93],"were":[98,114],"measured,":[99],"on":[100],"weekly":[102],"basis,":[103],"an":[105],"11.74":[106],"T":[107],"Bruker":[108],"spectrometer.":[109],"Histological":[110],"immunocytochemical":[112],"sections":[113],"obtained":[115],"correlated":[120],"MR":[123],"results.":[124],"This":[125],"study":[126],"shows":[127],"that":[128],"can":[130,145],"vitro":[134],"bone,":[138],"development":[142],"be":[146],"MRM":[149]},"counts_by_year":[],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2022-05-12T00:00:00"}