{"id":"https://openalex.org/W4242351272","doi":"https://doi.org/10.1016/j.ygyno.2020.05.465","title":"Development of a longitudinal combined biomarker algorithm for early detection of ovarian cancer","display_name":"Development of a longitudinal combined biomarker algorithm for early detection of ovarian cancer","publication_year":2020,"publication_date":"2020-10-01","ids":{"openalex":"https://openalex.org/W4242351272","doi":"https://doi.org/10.1016/j.ygyno.2020.05.465"},"language":"en","primary_location":{"id":"doi:10.1016/j.ygyno.2020.05.465","doi":"https://doi.org/10.1016/j.ygyno.2020.05.465","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ygyno.2020.05.465","pdf_url":null,"source":{"id":"https://openalex.org/S2574783","display_name":"Gynecologic Oncology","issn_l":"0090-8258","issn":["0090-8258","1095-6859"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gynecologic Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022231292","display_name":"Scott E. Lentz","orcid":"https://orcid.org/0000-0002-9435-2570","observed_orcids":["https://orcid.org/0000-0002-9435-2570"]},"institutions":[{"id":"https://openalex.org/I1343052199","display_name":"Kaiser Permanente","ror":"https://ror.org/00t60zh31","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1343052199"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"S.E. Lentz","raw_affiliation_strings":["Kaiser Permanente Medical Group, Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kaiser Permanente Medical Group, Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1343052199"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007718457","display_name":"C. Bethan Powell","orcid":"https://orcid.org/0000-0002-3599-1655","observed_orcids":["https://orcid.org/0000-0002-3599-1655"]},"institutions":[{"id":"https://openalex.org/I4405284138","display_name":"Kaiser Permanente Northern California","ror":"https://ror.org/0302f6d89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343052199","https://openalex.org/I4405284138"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.B. Powell","raw_affiliation_strings":["Kaiser Permanente Northern California, San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kaiser Permanente Northern California, San Francisco, CA, USA","institution_ids":["https://openalex.org/I4405284138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069743065","display_name":"Reina Haque","orcid":"https://orcid.org/0000-0001-8563-3330","observed_orcids":["https://orcid.org/0000-0001-8563-3330"]},"institutions":[{"id":"https://openalex.org/I1343052199","display_name":"Kaiser Permanente","ror":"https://ror.org/00t60zh31","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1343052199"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Haque","raw_affiliation_strings":["Kaiser Permanente Southern California, Pasadena, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kaiser Permanente Southern California, Pasadena, CA, USA","institution_ids":["https://openalex.org/I1343052199"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112264606","display_name":"M.A. Armstrong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343052199","display_name":"Kaiser Permanente","ror":"https://ror.org/00t60zh31","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1343052199"]},{"id":"https://openalex.org/I4405284138","display_name":"Kaiser Permanente Northern California","ror":"https://ror.org/0302f6d89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343052199","https://openalex.org/I4405284138"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.A. Armstrong","raw_affiliation_strings":["Kaiser Permanente Northern California Division of Research, Oakland, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kaiser Permanente Northern California Division of Research, Oakland, CA, USA","institution_ids":["https://openalex.org/I1343052199","https://openalex.org/I4405284138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057245448","display_name":"Matthew Linley Anderson","orcid":"https://orcid.org/0000-0002-2081-4672","observed_orcids":["https://orcid.org/0000-0002-2081-4672"]},"institutions":[{"id":"https://openalex.org/I4405284138","display_name":"Kaiser Permanente Northern California","ror":"https://ror.org/0302f6d89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343052199","https://openalex.org/I4405284138"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Anderson","raw_affiliation_strings":["Kaiser Permanente Northern California, Oakland, CA, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kaiser Permanente Northern California, Oakland, CA, USA,","institution_ids":["https://openalex.org/I4405284138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073172110","display_name":"Giulia Chillemi","orcid":"https://orcid.org/0000-0001-5789-3581","observed_orcids":["https://orcid.org/0000-0001-5789-3581"]},"institutions":[{"id":"https://openalex.org/I4405284138","display_name":"Kaiser Permanente Northern California","ror":"https://ror.org/0302f6d89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343052199","https://openalex.org/I4405284138"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G. Chillemi","raw_affiliation_strings":["Kaiser Permanente Northern California, Oakland, CA, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kaiser Permanente Northern California, Oakland, CA, USA,","institution_ids":["https://openalex.org/I4405284138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013063227","display_name":"Sally Fontamillas Shaw","orcid":"https://orcid.org/0000-0002-6553-1772","observed_orcids":["https://orcid.org/0000-0002-6553-1772"]},"institutions":[{"id":"https://openalex.org/I1343052199","display_name":"Kaiser Permanente","ror":"https://ror.org/00t60zh31","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1343052199"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Shaw","raw_affiliation_strings":["Kaiser Permanente Southern California, Pasadena, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kaiser Permanente Southern California, Pasadena, CA, USA","institution_ids":["https://openalex.org/I1343052199"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088367844","display_name":"M.M. Alvarado","orcid":"https://orcid.org/0009-0008-3414-3057","observed_orcids":["https://orcid.org/0009-0008-3414-3057"]},"institutions":[{"id":"https://openalex.org/I1343052199","display_name":"Kaiser Permanente","ror":"https://ror.org/00t60zh31","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1343052199"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.M. Alvarado","raw_affiliation_strings":["Kaiser Permanente Southern California, Pasadena, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kaiser Permanente Southern California, Pasadena, CA, USA","institution_ids":["https://openalex.org/I1343052199"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031698839","display_name":"Lawrence H. Kushi","orcid":"https://orcid.org/0000-0001-9136-1175","observed_orcids":["https://orcid.org/0000-0001-9136-1175"]},"institutions":[{"id":"https://openalex.org/I4405284138","display_name":"Kaiser Permanente Northern California","ror":"https://ror.org/0302f6d89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343052199","https://openalex.org/I4405284138"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Kushi","raw_affiliation_strings":["Kaiser Permanente Northern California, Oakland, CA, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kaiser Permanente Northern California, Oakland, CA, USA,","institution_ids":["https://openalex.org/I4405284138"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021748600","display_name":"Steven J. Skates","orcid":"https://orcid.org/0000-0001-9249-4316","observed_orcids":["https://orcid.org/0000-0001-9249-4316"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Skates","raw_affiliation_strings":["MGH, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MGH, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5022231292"],"corresponding_institution_ids":["https://openalex.org/I1343052199"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.36231814,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"159","issue":null,"first_page":"267","last_page":"268"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.9253000020980835,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.9253000020980835,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.07400000095367432,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"ovarian cancer","score":0.9800000190734863},{"id":"https://openalex.org/keywords/early-detection","display_name":"early detection","score":0.9210000038146973},{"id":"https://openalex.org/keywords/ca125","display_name":"CA125","score":0.9229999780654907},{"id":"https://openalex.org/keywords/he4","display_name":"HE4","score":0.9980000257492065},{"id":"https://openalex.org/keywords/longitudinal-biomarkers","display_name":"longitudinal biomarkers","score":0.796999990940094},{"id":"https://openalex.org/keywords/brca-mutation-carriers","display_name":"BRCA mutation carriers","score":0.8629999756813049},{"id":"https://openalex.org/keywords/cancer-surveillance","display_name":"cancer surveillance","score":0.9020000100135803}],"concepts":[{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.8585885763168335},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8288224935531616},{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.7092655897140503},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5652549266815186},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.43095239996910095},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39995241165161133},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.39609670639038086},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.09005779027938843},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07134401798248291},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06068339943885803}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.ygyno.2020.05.465","doi":"https://doi.org/10.1016/j.ygyno.2020.05.465","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ygyno.2020.05.465","pdf_url":null,"source":{"id":"https://openalex.org/S2574783","display_name":"Gynecologic Oncology","issn_l":"0090-8258","issn":["0090-8258","1095-6859"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gynecologic Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3090123795","https://openalex.org/W2951976776","https://openalex.org/W2563731577","https://openalex.org/W2938230940","https://openalex.org/W3042643553","https://openalex.org/W2285870893","https://openalex.org/W2796287172","https://openalex.org/W2324981521","https://openalex.org/W2397128306","https://openalex.org/W7099650577"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2022-05-12T00:00:00"}