{"id":"https://openalex.org/W4241331210","doi":"https://doi.org/10.1007/978-3-030-11123-6_6","title":"Retinoblastoma Tumorigenesis","display_name":"Retinoblastoma Tumorigenesis","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W4241331210","doi":"https://doi.org/10.1007/978-3-030-11123-6_6"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-030-11123-6_6","doi":"https://doi.org/10.1007/978-3-030-11123-6_6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-030-11123-6_6","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Ophthalmic Oncology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4288947979","display_name":"Clinical Ophthalmic Oncology"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054120784","display_name":"Rachel Christine Brennan","orcid":"https://orcid.org/0000-0002-2090-4395","observed_orcids":["https://orcid.org/0000-0002-2090-4395"]},"institutions":[{"id":"https://openalex.org/I1313298211","display_name":"St. Jude Children's Research Hospital","ror":"https://ror.org/02r3e0967","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1313298211","https://openalex.org/I2802152183"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Rachel C. Brennan","raw_affiliation_strings":["Department of Oncology, St. Jude Children\u2019s Research Hospital, Memphis, TN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, St. Jude Children\u2019s Research Hospital, Memphis, TN, USA","institution_ids":["https://openalex.org/I1313298211"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023634801","display_name":"Michael A. Dyer","orcid":"https://orcid.org/0000-0003-4027-4850","observed_orcids":["https://orcid.org/0000-0003-4027-4850"]},"institutions":[{"id":"https://openalex.org/I1313298211","display_name":"St. Jude Children's Research Hospital","ror":"https://ror.org/02r3e0967","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1313298211","https://openalex.org/I2802152183"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael A. Dyer","raw_affiliation_strings":["Department of Developmental Neurobiology, St. Jude Children\u2019s Research Hospital, Memphis, TN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental Neurobiology, St. Jude Children\u2019s Research Hospital, Memphis, TN, USA","institution_ids":["https://openalex.org/I1313298211"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5054120784"],"corresponding_institution_ids":["https://openalex.org/I1313298211"],"apc_list":null,"apc_paid":null,"fwci":1.6256,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.84094256,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"67","last_page":"77"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11328","display_name":"Ocular Oncology and Treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11328","display_name":"Ocular Oncology and Treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12989","display_name":"Ocular Disorders and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinoblastoma","display_name":"retinoblastoma","score":1.0},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/rb1-gene","display_name":"RB1 gene","score":0.9769999980926514},{"id":"https://openalex.org/keywords/biallelic-inactivation","display_name":"biallelic inactivation","score":0.9869999885559082},{"id":"https://openalex.org/keywords/epigenetic-events","display_name":"epigenetic events","score":0.7689999938011169},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.8429999947547913},{"id":"https://openalex.org/keywords/animal-models","display_name":"animal models","score":0.7509999871253967},{"id":"https://openalex.org/keywords/stem-cells","display_name":"stem cells","score":0.6769999861717224}],"concepts":[{"id":"https://openalex.org/C2776577112","wikidata":"https://www.wikidata.org/wiki/Q500695","display_name":"Retinoblastoma","level":3,"score":0.9536687135696411},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.7478771209716797},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.634143590927124},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49694016575813293},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.41106146574020386},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34699302911758423},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2900353670120239},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.26510775089263916}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-030-11123-6_6","doi":"https://doi.org/10.1007/978-3-030-11123-6_6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-030-11123-6_6","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Ophthalmic Oncology","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":68,"referenced_works":["https://openalex.org/W86409836","https://openalex.org/W1504221303","https://openalex.org/W1741394036","https://openalex.org/W1802167741","https://openalex.org/W1973757037","https://openalex.org/W1978371504","https://openalex.org/W1984328656","https://openalex.org/W1992708996","https://openalex.org/W1995564674","https://openalex.org/W1997399224","https://openalex.org/W2000649021","https://openalex.org/W2004497068","https://openalex.org/W2011912935","https://openalex.org/W2017599618","https://openalex.org/W2022507045","https://openalex.org/W2022929716","https://openalex.org/W2033309625","https://openalex.org/W2033364737","https://openalex.org/W2035975217","https://openalex.org/W2039798579","https://openalex.org/W2041662769","https://openalex.org/W2049133549","https://openalex.org/W2051863115","https://openalex.org/W2053984905","https://openalex.org/W2055363456","https://openalex.org/W2055764675","https://openalex.org/W2061891352","https://openalex.org/W2063367127","https://openalex.org/W2064110274","https://openalex.org/W2068299048","https://openalex.org/W2070831760","https://openalex.org/W2073278946","https://openalex.org/W2074498796","https://openalex.org/W2075858335","https://openalex.org/W2077858999","https://openalex.org/W2078801384","https://openalex.org/W2081367622","https://openalex.org/W2086322317","https://openalex.org/W2087896991","https://openalex.org/W2090982381","https://openalex.org/W2094525939","https://openalex.org/W2099742439","https://openalex.org/W2103784396","https://openalex.org/W2105081612","https://openalex.org/W2109611574","https://openalex.org/W2114268866","https://openalex.org/W2116402236","https://openalex.org/W2123528350","https://openalex.org/W2127946085","https://openalex.org/W2132888849","https://openalex.org/W2134890602","https://openalex.org/W2136400910","https://openalex.org/W2136718273","https://openalex.org/W2137187201","https://openalex.org/W2141596803","https://openalex.org/W2141680498","https://openalex.org/W2142877023","https://openalex.org/W2144490778","https://openalex.org/W2145596465","https://openalex.org/W2148523790","https://openalex.org/W2154194316","https://openalex.org/W2162139554","https://openalex.org/W2162608167","https://openalex.org/W2163570884","https://openalex.org/W2164157837","https://openalex.org/W2167228223","https://openalex.org/W2502558778","https://openalex.org/W2611327990"],"related_works":["https://openalex.org/W2025384756","https://openalex.org/W7163811953","https://openalex.org/W2408557296","https://openalex.org/W2324002927","https://openalex.org/W4398200392","https://openalex.org/W1992744288","https://openalex.org/W2767688859","https://openalex.org/W2154509640","https://openalex.org/W2002640210","https://openalex.org/W2019632767"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2022-05-12T00:00:00"}