{"id":"https://openalex.org/W4241248860","doi":"https://doi.org/10.1001/jama.1967.03130020033007","title":"Hyperglyceridemia in Coronary Artery Disease and Its Management","display_name":"Hyperglyceridemia in Coronary Artery Disease and Its Management","publication_year":1967,"publication_date":"1967-07-10","ids":{"openalex":"https://openalex.org/W4241248860","doi":"https://doi.org/10.1001/jama.1967.03130020033007","mag":"1982467556","pmid":"https://pubmed.ncbi.nlm.nih.gov/6072346"},"language":"en","primary_location":{"id":"doi:10.1001/jama.1967.03130020033007","doi":"https://doi.org/10.1001/jama.1967.03130020033007","is_oa":false,"landing_page_url":"https://doi.org/10.1001/jama.1967.03130020033007","pdf_url":null,"source":{"id":"https://openalex.org/S172573765","display_name":"JAMA","issn_l":"0002-9955","issn":["0002-9955","0098-7484","1538-3598","2376-8118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA: The Journal of the American Medical Association","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012879474","display_name":"P. T. Kuo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"P. T. Kuo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5012879474"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":14.97,"has_fulltext":false,"cited_by_count":57,"citation_normalized_percentile":{"value":0.99219873,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"201","issue":"2","first_page":"87","last_page":"94"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.7383000254631042,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.7383000254631042,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.1386999934911728,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.1185000017285347,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypertriglyceridemia","display_name":"hypertriglyceridemia","score":0.9210000038146973},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.9340000152587891},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.8199999928474426},{"id":"https://openalex.org/keywords/plasma-lipoproteins","display_name":"serum lipoproteins","score":0.7379999756813049},{"id":"https://openalex.org/keywords/paper-electrophoresis","display_name":"paper electrophoresis","score":0.7760000228881836},{"id":"https://openalex.org/keywords/sugar-free-diet","display_name":"sugar-free diet","score":0.7889999747276306},{"id":"https://openalex.org/keywords/carbohydrate-restriction","display_name":"carbohydrate restriction","score":0.43299999833106995},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.8510000109672546}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8326002359390259},{"id":"https://openalex.org/C2778977261","wikidata":"https://www.wikidata.org/wiki/Q11358","display_name":"Carbohydrate","level":2,"score":0.7330795526504517},{"id":"https://openalex.org/C2779091943","wikidata":"https://www.wikidata.org/wiki/Q1079120","display_name":"Hyperlipidemia","level":3,"score":0.6941252946853638},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.6897116899490356},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6353461742401123},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.593646764755249},{"id":"https://openalex.org/C17093226","wikidata":"https://www.wikidata.org/wiki/Q2734081","display_name":"Carbohydrate metabolism","level":2,"score":0.5558028221130371},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.521741509437561},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5063158273696899},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.46498459577560425},{"id":"https://openalex.org/C2780485761","wikidata":"https://www.wikidata.org/wiki/Q275157","display_name":"Blood sugar","level":3,"score":0.4300639033317566},{"id":"https://openalex.org/C141359234","wikidata":"https://www.wikidata.org/wiki/Q2734301","display_name":"Lipogenesis","level":3,"score":0.41520100831985474},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.13701629638671875}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001797","descriptor_name":"Blood Protein Electrophoresis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D004035","descriptor_name":"Diet Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004040","descriptor_name":"Dietary Carbohydrates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004041","descriptor_name":"Dietary Fats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004796","descriptor_name":"Clinical Enzyme Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005989","descriptor_name":"Glycerides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010743","descriptor_name":"Phospholipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D050260","descriptor_name":"Carbohydrate Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1001/jama.1967.03130020033007","doi":"https://doi.org/10.1001/jama.1967.03130020033007","is_oa":false,"landing_page_url":"https://doi.org/10.1001/jama.1967.03130020033007","pdf_url":null,"source":{"id":"https://openalex.org/S172573765","display_name":"JAMA","issn_l":"0002-9955","issn":["0002-9955","0098-7484","1538-3598","2376-8118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA: The Journal of the American Medical Association","raw_type":"journal-article"},{"id":"doi:10.1001/jama.201.2.87","doi":"https://doi.org/10.1001/jama.201.2.87","is_oa":false,"landing_page_url":"https://doi.org/10.1001/jama.201.2.87","pdf_url":null,"source":{"id":"https://openalex.org/S172573765","display_name":"JAMA","issn_l":"0002-9955","issn":["0002-9955","0098-7484","1538-3598","2376-8118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA: The Journal of the American Medical Association","raw_type":"journal-article"},{"id":"pmid:6072346","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6072346","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA","raw_type":"Journal Article"},{"id":"mag:1982467556","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6072346","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W87482027","https://openalex.org/W1513741126","https://openalex.org/W1955700461","https://openalex.org/W1994331801","https://openalex.org/W1996392591","https://openalex.org/W2007912128","https://openalex.org/W2008869420","https://openalex.org/W2012481132","https://openalex.org/W2032123872","https://openalex.org/W2033113241","https://openalex.org/W2070130099","https://openalex.org/W2087144124","https://openalex.org/W2092470996","https://openalex.org/W2130730237","https://openalex.org/W2143107185","https://openalex.org/W2181885523","https://openalex.org/W2286499920","https://openalex.org/W2406661052","https://openalex.org/W2442031647"],"related_works":["https://openalex.org/W2068655625","https://openalex.org/W2104373867","https://openalex.org/W2053183829","https://openalex.org/W1921386729","https://openalex.org/W7101101609","https://openalex.org/W2013485790","https://openalex.org/W4413178727","https://openalex.org/W2027712668","https://openalex.org/W2077282287","https://openalex.org/W1987321814"],"abstract_inverted_index":{"Different":[0],"laboratory":[1],"and":[2,50,56,106],"metabolic":[3,25],"studies":[4,20,26],"were":[5,27,66,98],"used":[6],"to":[7,29,68,90,100,132],"obtain":[8],"an":[9,85],"etiologic":[10],"classification":[11],"of":[12,34,62,130],"hyperlipidemia":[13],"in":[14,103,113],"286":[15,64],"patients":[16,65],"with":[17,84,115,126],"atherosclerosis.":[18],"The":[19,117],"showed":[21],"that":[22],"although":[23],"time-consuming":[24],"required":[28],"clearly":[30],"establish":[31],"the":[32,35,63],"nature":[33],"basic":[36],"disturbance,":[37],"useful":[38],"information":[39],"could":[40],"usually":[41],"be":[42,101],"obtained":[43],"by":[44,122],"serum":[45,51],"lipoprotein":[46],"analysis":[47],"(paper":[48],"electrophoresis)":[49],"lipid":[52],"determinations":[53],"(cholesterol,":[54],"phospholipid,":[55],"triglyceride":[57,105],"concentrations).":[58],"More":[59],"than":[60],"90%":[61],"found":[67,112],"have":[69],"hyperglyceridemia":[70,109],"derived":[71],"from":[72,76,96],"increased":[73],"endogenous":[74],"lipogenesis":[75],"carbohydrate.":[77],"This":[78],"abnormal":[79,118],"carbohydrate":[80,88,128],"sensitivity":[81],"was":[82,110,120],"revealed":[83],"ad":[86],"libitum":[87],"(35%":[89],"40%)":[91],"diet.":[92],"Since":[93],"lipoproteins":[94],"synthesized":[95],"carbohydrates":[97],"shown":[99],"rich":[102],"both":[104],"cholesterol,":[107],"carbohydrate-sensitive":[108],"frequently":[111],"association":[114],"hypercholesteremia.":[116],"metabolism":[119],"controlled":[121],"a":[123,127],"sugar-free":[124],"diet,":[125],"allowance":[129],"125":[131],"150":[133],"gm":[134],"supplied":[135],"as":[136],"starches.":[137]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2022-05-12T00:00:00"}