{"id":"https://openalex.org/W4240946835","doi":"https://doi.org/10.1016/j.bpj.2013.11.2750","title":"Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29","display_name":"Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W4240946835","doi":"https://doi.org/10.1016/j.bpj.2013.11.2750"},"language":"en","primary_location":{"id":"doi:10.1016/j.bpj.2013.11.2750","doi":"https://doi.org/10.1016/j.bpj.2013.11.2750","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2013.11.2750","pdf_url":"http://www.cell.com/article/S0006349513040071/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0006349513040071/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034288504","display_name":"Yaser Hashem","orcid":"https://orcid.org/0000-0003-4264-5918","observed_orcids":["https://orcid.org/0000-0003-4264-5918"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yaser Hashem","raw_affiliation_strings":["Columbia University, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081052258","display_name":"Am\u00e9d\u00e9e des Georges","orcid":"https://orcid.org/0000-0002-9704-3781","observed_orcids":["https://orcid.org/0000-0002-9704-3781"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amedee des Georges","raw_affiliation_strings":["Columbia University, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069976705","display_name":"Vidya Dhote","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181697535","display_name":"SUNY Downstate Health Sciences University","ror":"https://ror.org/0041qmd21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I181697535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vidya Dhote","raw_affiliation_strings":["SUNY Downstate Medical Center, Brooklyn, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SUNY Downstate Medical Center, Brooklyn, NY, USA","institution_ids":["https://openalex.org/I181697535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020915161","display_name":"Robert Ezra Langlois","orcid":"https://orcid.org/0000-0003-1779-4786","observed_orcids":["https://orcid.org/0000-0003-1779-4786"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Langlois","raw_affiliation_strings":["Columbia University, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022258349","display_name":"Hstau Y. Liao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hstau Y. Liao","raw_affiliation_strings":["Columbia University, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088775613","display_name":"Robert A. Grassucci","orcid":"https://orcid.org/0000-0002-1437-1537","observed_orcids":["https://orcid.org/0000-0002-1437-1537"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert A. Grassucci","raw_affiliation_strings":["Columbia University, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009915941","display_name":"Christopher U.T. Hellen","orcid":"https://orcid.org/0000-0002-3982-2090","observed_orcids":["https://orcid.org/0000-0002-3982-2090"]},"institutions":[{"id":"https://openalex.org/I181697535","display_name":"SUNY Downstate Health Sciences University","ror":"https://ror.org/0041qmd21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I181697535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher U.T. Hellen","raw_affiliation_strings":["SUNY Downstate Medical Center, Brooklyn, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SUNY Downstate Medical Center, Brooklyn, NY, USA","institution_ids":["https://openalex.org/I181697535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067570812","display_name":"Tatyana V. Pestova","orcid":"https://orcid.org/0000-0003-3543-256X","observed_orcids":["https://orcid.org/0000-0003-3543-256X"]},"institutions":[{"id":"https://openalex.org/I181697535","display_name":"SUNY Downstate Health Sciences University","ror":"https://ror.org/0041qmd21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I181697535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tatyana V. Pestova","raw_affiliation_strings":["SUNY Downstate Medical Center, Brooklyn, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SUNY Downstate Medical Center, Brooklyn, NY, USA","institution_ids":["https://openalex.org/I181697535"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042892654","display_name":"Joachim Frank","orcid":"https://orcid.org/0000-0001-5449-6943","observed_orcids":["https://orcid.org/0000-0001-5449-6943","https://orcid.org/0000-0002-2442-1112"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joachim Frank","raw_affiliation_strings":["Columbia University, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.1366,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.53580729,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"106","issue":"2","first_page":"492a","last_page":"492a"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/43s-preinitiation-complex","display_name":"43S preinitiation complex","score":0.9909999966621399},{"id":"https://openalex.org/keywords/eif2","display_name":"eIF2","score":0.5730000138282776},{"id":"https://openalex.org/keywords/eif3","display_name":"eIF3","score":0.8460000157356262},{"id":"https://openalex.org/keywords/40s-ribosomal-subunit","display_name":"40S ribosomal subunit","score":0.8600000143051147},{"id":"https://openalex.org/keywords/eif2alpha","display_name":"eIF2\u03b1","score":0.47699999809265137},{"id":"https://openalex.org/keywords/ternary-complex","display_name":"ternary complex","score":0.878000020980835},{"id":"https://openalex.org/keywords/mrna-scanning","display_name":"mRNA scanning","score":0.6119999885559082},{"id":"https://openalex.org/keywords/translation-initiation","display_name":"translation initiation","score":0.7149999737739563},{"id":"https://openalex.org/keywords/ribosome-structure","display_name":"ribosome structure","score":0.6800000071525574}],"concepts":[{"id":"https://openalex.org/C188740287","wikidata":"https://www.wikidata.org/wiki/Q423333","display_name":"Transcription preinitiation complex","level":5,"score":0.8508975505828857},{"id":"https://openalex.org/C301363","wikidata":"https://www.wikidata.org/wiki/Q4637383","display_name":"Eukaryotic Small Ribosomal Subunit","level":5,"score":0.6856921911239624},{"id":"https://openalex.org/C97154109","wikidata":"https://www.wikidata.org/wiki/Q906570","display_name":"Eukaryotic initiation factor","level":5,"score":0.6216743588447571},{"id":"https://openalex.org/C93734116","wikidata":"https://www.wikidata.org/wiki/Q1017133","display_name":"eIF2","level":5,"score":0.5837690830230713},{"id":"https://openalex.org/C62493599","wikidata":"https://www.wikidata.org/wiki/Q424137","display_name":"Initiation factor","level":5,"score":0.5819723606109619},{"id":"https://openalex.org/C4718897","wikidata":"https://www.wikidata.org/wiki/Q5408698","display_name":"Eukaryotic translation","level":5,"score":0.502800464630127},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4819081127643585},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45625126361846924},{"id":"https://openalex.org/C77430603","wikidata":"https://www.wikidata.org/wiki/Q166992","display_name":"Internal ribosome entry site","level":5,"score":0.42195045948028564},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.19852489233016968},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17788198590278625},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.07933863997459412},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.06585213541984558},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bpj.2013.11.2750","doi":"https://doi.org/10.1016/j.bpj.2013.11.2750","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2013.11.2750","pdf_url":"http://www.cell.com/article/S0006349513040071/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.bpj.2013.11.2750","doi":"https://doi.org/10.1016/j.bpj.2013.11.2750","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2013.11.2750","pdf_url":"http://www.cell.com/article/S0006349513040071/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4240946835.pdf"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2157495054","https://openalex.org/W2531412474","https://openalex.org/W2164754533","https://openalex.org/W4200220265","https://openalex.org/W4412402053","https://openalex.org/W2337839941","https://openalex.org/W2793963773","https://openalex.org/W2003427751","https://openalex.org/W2441091975","https://openalex.org/W7024968188"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2022-05-12T00:00:00"}