{"id":"https://openalex.org/W4240926765","doi":"https://doi.org/10.1016/j.bpj.2011.11.1718","title":"Design and Application of a Class of Sensors to Monitor Ca2+ Dynamics in High Ca2+ Concentration Cellular Compartments","display_name":"Design and Application of a Class of Sensors to Monitor Ca2+ Dynamics in High Ca2+ Concentration Cellular Compartments","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W4240926765","doi":"https://doi.org/10.1016/j.bpj.2011.11.1718"},"language":"en","primary_location":{"id":"doi:10.1016/j.bpj.2011.11.1718","doi":"https://doi.org/10.1016/j.bpj.2011.11.1718","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2011.11.1718","pdf_url":"http://www.cell.com/article/S0006349511030669/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0006349511030669/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058254577","display_name":"Shen Tang","orcid":"https://orcid.org/0000-0003-1776-2960","observed_orcids":["https://orcid.org/0000-0003-1776-2960"]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shen Tang","raw_affiliation_strings":["Georgia State University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia State University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036080145","display_name":"Hing\u2010Cheung Wong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hing-Cheung Wong","raw_affiliation_strings":["Georgia State University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia State University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100751416","display_name":"Zhongmin Wang","orcid":"https://orcid.org/0000-0001-7994-4538","observed_orcids":["https://orcid.org/0000-0001-7994-4538"]},"institutions":[{"id":"https://openalex.org/I4405269449","display_name":"Wake Forest University Health Sciences","ror":"https://ror.org/046r1r105","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]},{"id":"https://openalex.org/I47251452","display_name":"Wake Forest University","ror":"https://ror.org/0207ad724","country_code":"US","type":"education","lineage":["https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhong-Min Wang","raw_affiliation_strings":["Wake Forest University School of Medicine, Winston-Salem, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest University School of Medicine, Winston-Salem, NC, USA","institution_ids":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044336968","display_name":"Yun Huang","orcid":"https://orcid.org/0000-0001-5950-9168","observed_orcids":["https://orcid.org/0000-0001-5950-9168"]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yun Huang","raw_affiliation_strings":["Georgia State University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia State University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101110044","display_name":"Jin Zou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jin Zou","raw_affiliation_strings":["Georgia State University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia State University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006260522","display_name":"You Zhuo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"You Zhuo","raw_affiliation_strings":["Georgia State University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia State University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085694265","display_name":"Andrea Pennati","orcid":"https://orcid.org/0000-0001-6211-7480","observed_orcids":["https://orcid.org/0000-0001-6211-7480","https://orcid.org/0000-0001-8435-1999"]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrea Pennati","raw_affiliation_strings":["Georgia State University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia State University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032766595","display_name":"Giovanni Gadda","orcid":"https://orcid.org/0000-0002-7508-4195","observed_orcids":["https://orcid.org/0000-0002-7508-4195"]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Giovanni Gadda","raw_affiliation_strings":["Georgia State University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia State University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013575262","display_name":"Osvaldo Delbono","orcid":"https://orcid.org/0000-0002-1613-8202","observed_orcids":["https://orcid.org/0000-0002-1613-8202"]},"institutions":[{"id":"https://openalex.org/I4405269449","display_name":"Wake Forest University Health Sciences","ror":"https://ror.org/046r1r105","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]},{"id":"https://openalex.org/I47251452","display_name":"Wake Forest University","ror":"https://ror.org/0207ad724","country_code":"US","type":"education","lineage":["https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Osvaldo Delbono","raw_affiliation_strings":["Wake Forest University School of Medicine, Winston-Salem, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest University School of Medicine, Winston-Salem, NC, USA","institution_ids":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062706695","display_name":"Jenny Jie Yang","orcid":"https://orcid.org/0000-0002-2310-7658","observed_orcids":["https://orcid.org/0000-0002-2310-7658","https://orcid.org/0009-0007-1543-7001"]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jenny J. Yang","raw_affiliation_strings":["Georgia State University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia State University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I181565077"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.4154,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.66156522,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"102","issue":"3","first_page":"312a","last_page":"312a"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9179999828338623,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9179999828338623,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11204","display_name":"Ion Channels and Receptors","score":0.03500000014901161,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.010200000368058681,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/genetically-encoded-calcium-indicators","display_name":"genetically encoded calcium indicators","score":0.871999979019165},{"id":"https://openalex.org/keywords/enhanced-green-fluorescent-protein","display_name":"enhanced green fluorescent protein","score":0.5879999995231628},{"id":"https://openalex.org/keywords/endoplasmic-reticulum-calcium","display_name":"endoplasmic reticulum calcium","score":0.8199999928474426},{"id":"https://openalex.org/keywords/sarcoplasmic-reticulum-calcium","display_name":"sarcoplasmic reticulum calcium","score":0.9340000152587891},{"id":"https://openalex.org/keywords/calcium-release-kinetics","display_name":"calcium release kinetics","score":0.7789999842643738},{"id":"https://openalex.org/keywords/conformational-change","display_name":"conformational change","score":0.7480000257492065},{"id":"https://openalex.org/keywords/muscle-aging","display_name":"muscle aging","score":0.37299999594688416},{"id":"https://openalex.org/keywords/flexor-digitorum-brevis","display_name":"flexor digitorum brevis","score":0.8690000176429749},{"id":"https://openalex.org/keywords/calcium-homeostasis","display_name":"calcium homeostasis","score":0.7459999918937683},{"id":"https://openalex.org/keywords/hela-cells","display_name":"HeLa cells","score":0.7369999885559082},{"id":"https://openalex.org/keywords/hek293-cells","display_name":"HEK293 cells","score":0.9200000166893005},{"id":"https://openalex.org/keywords/c2c12-myoblasts","display_name":"C2C12 myoblasts","score":0.9490000009536743}],"concepts":[{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.8200498819351196},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.6167426109313965},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5452159643173218},{"id":"https://openalex.org/C174510640","wikidata":"https://www.wikidata.org/wiki/Q489618","display_name":"HEK 293 cells","level":3,"score":0.529578447341919},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5248855948448181},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5150944590568542},{"id":"https://openalex.org/C60278653","wikidata":"https://www.wikidata.org/wiki/Q5008075","display_name":"C2C12","level":4,"score":0.4960101544857025},{"id":"https://openalex.org/C201571599","wikidata":"https://www.wikidata.org/wiki/Q5018840","display_name":"Calcium signaling","level":3,"score":0.48967817425727844},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.4871678054332733},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.45489659905433655},{"id":"https://openalex.org/C2781414619","wikidata":"https://www.wikidata.org/wiki/Q24785512","display_name":"SERCA","level":4,"score":0.45341500639915466},{"id":"https://openalex.org/C2777366897","wikidata":"https://www.wikidata.org/wiki/Q847482","display_name":"HeLa","level":3,"score":0.4372395873069763},{"id":"https://openalex.org/C87975464","wikidata":"https://www.wikidata.org/wiki/Q910704","display_name":"Calcium metabolism","level":3,"score":0.4218481183052063},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3445916175842285},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3400486707687378},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.1847001314163208},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.12249186635017395},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.07892954349517822},{"id":"https://openalex.org/C23265538","wikidata":"https://www.wikidata.org/wiki/Q300033","display_name":"ATPase","level":3,"score":0.0762646496295929},{"id":"https://openalex.org/C3763915","wikidata":"https://www.wikidata.org/wiki/Q3331437","display_name":"Myogenesis","level":3,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bpj.2011.11.1718","doi":"https://doi.org/10.1016/j.bpj.2011.11.1718","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2011.11.1718","pdf_url":"http://www.cell.com/article/S0006349511030669/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.bpj.2011.11.1718","doi":"https://doi.org/10.1016/j.bpj.2011.11.1718","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2011.11.1718","pdf_url":"http://www.cell.com/article/S0006349511030669/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4240926765.pdf"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2071599048","https://openalex.org/W2011815920","https://openalex.org/W2063625535","https://openalex.org/W784939668","https://openalex.org/W7100122986","https://openalex.org/W2023383439","https://openalex.org/W2597151353","https://openalex.org/W2417436959","https://openalex.org/W2089273450","https://openalex.org/W2585063939"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2022-05-12T00:00:00"}