{"id":"https://openalex.org/W4240780654","doi":"https://doi.org/10.1093/med/9780190215422.003.0011","title":"Genetics of PTSD","display_name":"Genetics of PTSD","publication_year":2016,"publication_date":"2016-08-01","ids":{"openalex":"https://openalex.org/W4240780654","doi":"https://doi.org/10.1093/med/9780190215422.003.0011"},"language":"en","primary_location":{"id":"doi:10.1093/med/9780190215422.003.0011","doi":"https://doi.org/10.1093/med/9780190215422.003.0011","is_oa":false,"landing_page_url":"https://doi.org/10.1093/med/9780190215422.003.0011","pdf_url":null,"source":{"id":"https://openalex.org/S4306463708","display_name":"Oxford University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxford Medicine Online","raw_type":"book"},"volume":null,"type":"book","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070636268","display_name":"Jennifer A. Sumner","orcid":"https://orcid.org/0000-0002-0217-7171","observed_orcids":["https://orcid.org/0000-0002-0217-7171"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jennifer A. Sumner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033994492","display_name":"Angela C. Bustamante","orcid":"https://orcid.org/0000-0001-8016-1733","observed_orcids":["https://orcid.org/0000-0001-8016-1733"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Angela C. Bustamante","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031482400","display_name":"Karestan Chase Koenen","orcid":"https://orcid.org/0000-0003-2978-7655","observed_orcids":["https://orcid.org/0000-0003-2978-7655","https://orcid.org/0000-0003-3293-4281"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Karestan C. Koenen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5026464787","display_name":"Monica Uddin","orcid":"https://orcid.org/0000-0001-7404-2068","observed_orcids":["https://orcid.org/0000-0001-7404-2068"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Monica Uddin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.35665796,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10242","display_name":"Posttraumatic Stress Disorder Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10242","display_name":"Posttraumatic Stress Disorder Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10426","display_name":"Child Abuse and Trauma","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/posttraumatic-stress-disorder","display_name":"post-traumatic stress disorder","score":0.9430000185966492},{"id":"https://openalex.org/keywords/heritability","display_name":"heritability","score":0.9110000133514404},{"id":"https://openalex.org/keywords/trauma-exposure","display_name":"trauma exposure","score":0.8560000061988831},{"id":"https://openalex.org/keywords/genetic-risk-factors","display_name":"genetic risk factors","score":0.9430000185966492},{"id":"https://openalex.org/keywords/candidate-genes","display_name":"candidate genes","score":0.6439999938011169},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"genome-wide association study","score":0.996999979019165},{"id":"https://openalex.org/keywords/gene-environment-interaction","display_name":"gene-environment interaction","score":0.9940000176429749},{"id":"https://openalex.org/keywords/epigenetics","display_name":"epigenetics","score":0.996999979019165},{"id":"https://openalex.org/keywords/genetic-markers","display_name":"genetic markers","score":0.6480000019073486},{"id":"https://openalex.org/keywords/resilience","display_name":"resilience","score":0.9010000228881836}],"concepts":[{"id":"https://openalex.org/C9287583","wikidata":"https://www.wikidata.org/wiki/Q5532883","display_name":"Genetic architecture","level":4,"score":0.6728451251983643},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.5897756814956665},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.4671902656555176},{"id":"https://openalex.org/C137176749","wikidata":"https://www.wikidata.org/wiki/Q4105337","display_name":"Psychological resilience","level":2,"score":0.45218154788017273},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.4481002986431122},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.42812296748161316},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35684406757354736},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2958247661590576},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2822844982147217},{"id":"https://openalex.org/C81941488","wikidata":"https://www.wikidata.org/wiki/Q853421","display_name":"Quantitative trait locus","level":3,"score":0.1779308319091797},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.13390865921974182},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.11930820345878601},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.09031283855438232}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/med/9780190215422.003.0011","doi":"https://doi.org/10.1093/med/9780190215422.003.0011","is_oa":false,"landing_page_url":"https://doi.org/10.1093/med/9780190215422.003.0011","pdf_url":null,"source":{"id":"https://openalex.org/S4306463708","display_name":"Oxford University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxford Medicine Online","raw_type":"book"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8999999761581421,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4235511095","https://openalex.org/W1638992340","https://openalex.org/W2515252412","https://openalex.org/W2059721824","https://openalex.org/W2394258935","https://openalex.org/W2142549069","https://openalex.org/W2795848893","https://openalex.org/W2590707139","https://openalex.org/W1497544452","https://openalex.org/W1964261039"],"abstract_inverted_index":{"Trauma":[0],"exposure":[1,15,63],"and":[2,11,53,74,97],"PTSD":[3,29],"are":[4,16],"heritable.":[5],"However,":[6],"the":[7,25,37,58,65,89,103],"mechanisms":[8],"of":[9,28,61,67],"risk":[10,44],"resilience":[12],"following":[13],"trauma":[14,62],"not":[17],"yet":[18],"well":[19],"understood,":[20],"suggesting":[21],"that":[22],"investigations":[23],"into":[24],"genetic":[26,43,106],"architecture":[27],"have":[30],"much":[31],"to":[32,94],"contribute.":[33],"This":[34],"chapter":[35,83],"reviews":[36],"rapidly":[38],"growing":[39],"literature":[40],"on":[41],"molecular":[42],"factors":[45],"for":[46,88,105,108],"PTSD,":[47,68],"including":[48],"findings":[49,78],"from":[50,79],"candidate":[51],"gene":[52],"genome-wide":[54],"association":[55],"studies.":[56,81],"Given":[57],"critical":[59],"role":[60],"in":[64,102],"onset":[66],"it":[69,92],"also":[70],"discusses":[71,98],"gene-environment":[72],"interplay,":[73],"highlights":[75],"some":[76],"recent":[77],"epigenetic":[80],"The":[82],"concludes":[84],"by":[85],"summarizing":[86],"considerations":[87],"field":[90],"as":[91],"continues":[93],"move":[95],"forward,":[96],"exciting":[99],"new":[100],"developments":[101],"search":[104],"markers":[107],"PTSD.":[109]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2022-05-12T00:00:00"}