{"id":"https://openalex.org/W4240145772","doi":"https://doi.org/10.1093/med/9780190228163.003.0021","title":"Functional Neuroimaging Studies in Obsessive-Compulsive Disorder: Overview and Synthesis","display_name":"Functional Neuroimaging Studies in Obsessive-Compulsive Disorder: Overview and Synthesis","publication_year":2017,"publication_date":"2017-10-01","ids":{"openalex":"https://openalex.org/W4240145772","doi":"https://doi.org/10.1093/med/9780190228163.003.0021"},"language":"en","primary_location":{"id":"doi:10.1093/med/9780190228163.003.0021","doi":"https://doi.org/10.1093/med/9780190228163.003.0021","is_oa":false,"landing_page_url":"https://doi.org/10.1093/med/9780190228163.003.0021","pdf_url":null,"source":{"id":"https://openalex.org/S4306463708","display_name":"Oxford University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxford Medicine Online","raw_type":"edited-book"},"volume":null,"type":"book","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019789422","display_name":"Brian P. Brennan","orcid":"https://orcid.org/0000-0001-5468-6552","observed_orcids":["https://orcid.org/0000-0001-5468-6552"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brian P. Brennan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5015892598","display_name":"Scott L. Rauch","orcid":"https://orcid.org/0000-0001-7699-6754","observed_orcids":["https://orcid.org/0000-0001-7699-6754"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Scott L. Rauch","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.6136,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.86591005,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11123","display_name":"Obsessive-Compulsive Spectrum Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11123","display_name":"Obsessive-Compulsive Spectrum Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obsessive-compulsive-disorder","display_name":"obsessive-compulsive disorder","score":1.0},{"id":"https://openalex.org/keywords/functional-connectivity","display_name":"functional connectivity","score":0.7570000290870667},{"id":"https://openalex.org/keywords/default-mode-network","display_name":"default mode network","score":0.9570000171661377},{"id":"https://openalex.org/keywords/frontoparietal-network","display_name":"frontoparietal network","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cognitive-control","display_name":"cognitive control","score":0.7870000004768372},{"id":"https://openalex.org/keywords/neuromodulation","display_name":"neuromodulation","score":0.746999979019165},{"id":"https://openalex.org/keywords/neurobiology-of-ocd","display_name":"neurobiology of OCD","score":0.7110000252723694},{"id":"https://openalex.org/keywords/intrinsic-brain-networks","display_name":"intrinsic brain networks","score":0.6679999828338623}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7834252715110779},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.7786190509796143},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6540775895118713},{"id":"https://openalex.org/C3017582312","wikidata":"https://www.wikidata.org/wiki/Q178190","display_name":"Obsessive compulsive","level":2,"score":0.6239888072013855},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.6038925647735596},{"id":"https://openalex.org/C52338299","wikidata":"https://www.wikidata.org/wiki/Q1004354","display_name":"Functional neuroimaging","level":3,"score":0.5936221480369568},{"id":"https://openalex.org/C66324658","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Resting state fMRI","level":2,"score":0.5848531723022461},{"id":"https://openalex.org/C141516989","wikidata":"https://www.wikidata.org/wiki/Q1182555","display_name":"Default mode network","level":3,"score":0.5668982267379761},{"id":"https://openalex.org/C27502469","wikidata":"https://www.wikidata.org/wiki/Q906343","display_name":"Dysfunctional family","level":2,"score":0.4971607029438019},{"id":"https://openalex.org/C182752723","wikidata":"https://www.wikidata.org/wiki/Q1474590","display_name":"Functional imaging","level":2,"score":0.4255504608154297},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.10895881056785583}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/med/9780190228163.003.0021","doi":"https://doi.org/10.1093/med/9780190228163.003.0021","is_oa":false,"landing_page_url":"https://doi.org/10.1093/med/9780190228163.003.0021","pdf_url":null,"source":{"id":"https://openalex.org/S4306463708","display_name":"Oxford University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxford Medicine Online","raw_type":"edited-book"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2530727894","https://openalex.org/W3044432632","https://openalex.org/W4232202002","https://openalex.org/W4240837710","https://openalex.org/W4225545026","https://openalex.org/W3131934418","https://openalex.org/W1985748616","https://openalex.org/W2069358979","https://openalex.org/W4404748207","https://openalex.org/W186125123"],"abstract_inverted_index":{"Studies":[0],"using":[1,22,39],"functional":[2,45,75],"neuroimaging":[3],"have":[4,50,72],"played":[5],"a":[6,28,95,142],"critical":[7],"role":[8,144],"in":[9,35,42,88,105,135,145],"the":[10,14,55,82,99,109,146],"current":[11],"understanding":[12],"of":[13,16,101,112,148],"neurobiology":[15],"obsessive-compulsive":[17],"disorder":[18],"(OCD).":[19],"Early":[20],"studies":[21,38,67],"positron":[23],"emission":[24],"tomography":[25],"(PET)":[26],"identified":[27,73],"core":[29,129],"cortico-striatal-thalamo-cortical":[30,102],"circuit":[31,103],"that":[32,124],"is":[33,120],"dysfunctional":[34],"OCD.":[36,64,149],"Subsequent":[37],"behavioral":[40],"paradigms":[41],"conjunction":[43],"with":[44],"magnetic":[46],"resonance":[47],"imaging":[48],"(fMRI)":[49],"provided":[51],"additional":[52],"information":[53],"about":[54],"neural":[56],"substrates":[57],"underlying":[58],"specific":[59],"psychological":[60],"processes":[61],"relevant":[62],"to":[63],"More":[65],"recently,":[66],"utilizing":[68],"resting":[69],"state":[70],"fMRI":[71],"abnormal":[74],"connectivity":[76],"within":[77],"intrinsic":[78],"brain":[79,117,125],"networks":[80,87],"including":[81],"default":[83],"mode":[84],"and":[85,107],"frontoparietal":[86,132],"OCD":[89,106],"patients.":[90],"Although":[91],"these":[92,116],"studies,":[93],"as":[94],"whole,":[96],"clearly":[97],"substantiate":[98],"model":[100],"dysfunction":[104],"support":[108],"continued":[110],"investigation":[111],"neuromodulatory":[113],"treatments":[114],"targeting":[115],"regions,":[118],"there":[119],"also":[121,140],"growing":[122],"evidence":[123],"regions":[126,133],"outside":[127],"this":[128],"circuit,":[130],"particularly":[131],"involved":[134],"cognitive":[136],"control":[137],"processes,":[138],"may":[139],"play":[141],"significant":[143],"pathophysiology":[147]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2022-05-12T00:00:00"}