{"id":"https://openalex.org/W4239230140","doi":"https://doi.org/10.1097/ccm.0000000000002225","title":"The authors reply","display_name":"The authors reply","publication_year":2017,"publication_date":"2017-02-18","ids":{"openalex":"https://openalex.org/W4239230140","doi":"https://doi.org/10.1097/ccm.0000000000002225","pmid":"https://pubmed.ncbi.nlm.nih.gov/28212230","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5500205"},"language":"en","primary_location":{"id":"doi:10.1097/ccm.0000000000002225","doi":"https://doi.org/10.1097/ccm.0000000000002225","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ccm.0000000000002225","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"letter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5500205","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003656182","display_name":"Andreas G\u00fcldner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210148226","display_name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","ror":"https://ror.org/03kk0s825","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210148226"]},{"id":"https://openalex.org/I4210162051","display_name":"University Hospital Carl Gustav Carus","ror":"https://ror.org/04za5zm41","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210162051"]},{"id":"https://openalex.org/I4387153105","display_name":"Instituto de Biof\u00edsica Carlos Chagas Filho","ror":"https://ror.org/051xsx468","country_code":"BR","type":"facility","lineage":["https://openalex.org/I122140584","https://openalex.org/I4387153105"]},{"id":"https://openalex.org/I78650965","display_name":"Technische Universit\u00e4t Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]},{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["BR","DE","IT","US"],"is_corresponding":false,"raw_author_name":"Andreas G\u00fcldner","raw_affiliation_strings":["Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Inte","Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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The remaining authors have disclosed that they do not have any potential conflicts of interest","IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Inte","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105","https://openalex.org/I78650965","https://openalex.org/I83816512"]},{"raw_affiliation_string":"Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I78650965","https://openalex.org/I83816512"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105","https://openalex.org/I78650965"]},{"raw_affiliation_string":"Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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The remaining authors have disclosed that they do not have any potential conflicts of interest","institution_ids":["https://openalex.org/I4210148226"]},{"raw_affiliation_string":"IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I83816512"]},{"raw_affiliation_string":"Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I4210162051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018593677","display_name":"Anja Braune","orcid":"https://orcid.org/0000-0001-7707-9413","observed_orcids":["https://orcid.org/0000-0001-7707-9413"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210148226","display_name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","ror":"https://ror.org/03kk0s825","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210148226"]},{"id":"https://openalex.org/I4210162051","display_name":"University Hospital Carl Gustav Carus","ror":"https://ror.org/04za5zm41","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210162051"]},{"id":"https://openalex.org/I4387153105","display_name":"Instituto de Biof\u00edsica Carlos Chagas Filho","ror":"https://ror.org/051xsx468","country_code":"BR","type":"facility","lineage":["https://openalex.org/I122140584","https://openalex.org/I4387153105"]},{"id":"https://openalex.org/I78650965","display_name":"Technische Universit\u00e4t Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]},{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["BR","DE","IT","US"],"is_corresponding":false,"raw_author_name":"Anja Braune","raw_affiliation_strings":["","Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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The remaining authors have disclosed that they do not have any potential conflicts of interest","IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I78650965","https://openalex.org/I83816512"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105","https://openalex.org/I78650965"]},{"raw_affiliation_string":"Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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The remaining authors have disclosed that they do not have any potential conflicts of interest","institution_ids":["https://openalex.org/I4210148226"]},{"raw_affiliation_string":"IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I83816512"]},{"raw_affiliation_string":"Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I4210162051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062600693","display_name":"Lorenzo Ball","orcid":"https://orcid.org/0000-0002-3876-4730","observed_orcids":["https://orcid.org/0000-0002-3876-4730"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard 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The remaining authors have disclosed that they do not have any potential conflicts of interest","IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105"]},{"raw_affiliation_string":"Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I78650965","https://openalex.org/I83816512"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105","https://openalex.org/I78650965"]},{"raw_affiliation_string":"Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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The remaining authors have disclosed that they do not have any potential conflicts of interest","IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I78650965","https://openalex.org/I83816512"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105","https://openalex.org/I78650965"]},{"raw_affiliation_string":"Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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Dr. Vidal Melo\u2019s institution received grant support from RO1 HL 121228, the National Institutes of Health (NIH), and Merck (current investigator initiated grant from Merck). He received support for article research from the NIH. Dr. Gama de Abreu received funding from Dr\u00e4ger Medical Deutschland GmbH, L\u00fcbeck, Germany, GE Healthcare, Paris, France, and from Ventinova, Eindhoven, Netherlands. The remaining authors have disclosed that they do not have any potential conflicts of interest","IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I78650965","https://openalex.org/I83816512"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105","https://openalex.org/I78650965"]},{"raw_affiliation_string":"Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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Dr. Vidal Melo\u2019s institution received grant support from RO1 HL 121228, the National Institutes of Health (NIH), and Merck (current investigator initiated grant from Merck). He received support for article research from the NIH. Dr. Gama de Abreu received funding from Dr\u00e4ger Medical Deutschland GmbH, L\u00fcbeck, Germany, GE Healthcare, Paris, France, and from Ventinova, Eindhoven, Netherlands. The remaining authors have disclosed that they do not have any potential conflicts of interest","IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I78650965","https://openalex.org/I83816512"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105","https://openalex.org/I78650965"]},{"raw_affiliation_string":"Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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The remaining authors have disclosed that they do not have any potential conflicts of interest","IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I78650965","https://openalex.org/I83816512"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105","https://openalex.org/I78650965"]},{"raw_affiliation_string":"Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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The remaining authors have disclosed that they do not have any potential conflicts of interest","IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I78650965","https://openalex.org/I83816512"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105","https://openalex.org/I78650965"]},{"raw_affiliation_string":"Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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The remaining authors have disclosed that they do not have any potential conflicts of interest","IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I78650965","https://openalex.org/I83816512"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105","https://openalex.org/I78650965"]},{"raw_affiliation_string":"Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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The remaining authors have disclosed that they do not have any potential conflicts of interest","IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I78650965","https://openalex.org/I83816512"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105","https://openalex.org/I78650965"]},{"raw_affiliation_string":"Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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The remaining authors have disclosed that they do not have any potential conflicts of interest","institution_ids":["https://openalex.org/I4210148226"]},{"raw_affiliation_string":"IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I83816512"]},{"raw_affiliation_string":"Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I4210162051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085792559","display_name":"Tilo Winkler","orcid":"https://orcid.org/0000-0002-7276-5550","observed_orcids":["https://orcid.org/0000-0002-7276-5550"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210148226","display_name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","ror":"https://ror.org/03kk0s825","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210148226"]},{"id":"https://openalex.org/I4210162051","display_name":"University Hospital Carl Gustav Carus","ror":"https://ror.org/04za5zm41","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210162051"]},{"id":"https://openalex.org/I4387153105","display_name":"Instituto de Biof\u00edsica Carlos Chagas Filho","ror":"https://ror.org/051xsx468","country_code":"BR","type":"facility","lineage":["https://openalex.org/I122140584","https://openalex.org/I4387153105"]},{"id":"https://openalex.org/I78650965","display_name":"Technische Universit\u00e4t Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]},{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["BR","DE","IT","US"],"is_corresponding":false,"raw_author_name":"Tilo Winkler","raw_affiliation_strings":["","Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. Dr. Vidal Melo\u2019s institution received grant support from RO1 HL 121228, the National Institutes of Health (NIH), and Merck (current investigator initiated grant from Merck). He received support for article research from the NIH. Dr. Gama de Abreu received funding from Dr\u00e4ger Medical Deutschland GmbH, L\u00fcbeck, Germany, GE Healthcare, Paris, France, and from Ventinova, Eindhoven, Netherlands. The remaining authors have disclosed that they do not have any potential conflicts of interest","IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","Institute of Nuclear Medicine, University Hospital Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and IRCCS San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy","institution_ids":["https://openalex.org/I78650965","https://openalex.org/I83816512"]},{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universit\u00e4t Dresden, Dresden, Germany, and Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I4387153105","https://openalex.org/I78650965"]},{"raw_affiliation_string":"Dr. Leme Silva received support for article research from CAPES, FAPERJ, CNPq. 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