{"id":"https://openalex.org/W4239101754","doi":"https://doi.org/10.3410/f.1161031.621490","title":"Faculty Opinions recommendation of TLR signals promote IL-6/IL-17-dependent transplant rejection.","display_name":"Faculty Opinions recommendation of TLR signals promote IL-6/IL-17-dependent transplant rejection.","publication_year":2009,"publication_date":"2009-06-05","ids":{"openalex":"https://openalex.org/W4239101754","doi":"https://doi.org/10.3410/f.1161031.621490"},"language":"en","primary_location":{"id":"doi:10.3410/f.1161031.621490","doi":"https://doi.org/10.3410/f.1161031.621490","is_oa":false,"landing_page_url":"https://doi.org/10.3410/f.1161031.621490","pdf_url":null,"source":{"id":"https://openalex.org/S4363604054","display_name":"Faculty Opinions \u2013 Post-Publication Peer Review of the Biomedical Literature","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Faculty Opinions \u2013 Post-Publication Peer Review of the Biomedical Literature","raw_type":"dataset"},"volume":null,"type":"peer-review","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028211848","display_name":"Mohamed H. Sayegh","orcid":"https://orcid.org/0000-0002-2847-588X","observed_orcids":["https://orcid.org/0000-0002-2847-588X"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohamed Sayegh","raw_affiliation_strings":["Transplantation Research Center, Brigham and Women's Hospital and Children's Hospital, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Transplantation Research Center, Brigham and Women's Hospital and Children's Hospital, USA","institution_ids":["https://openalex.org/I1283280774"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109053382","display_name":"Jessamyn Bagley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessamyn Bagley","raw_affiliation_strings":["Transplantation Research Center, Brigham and Women's Hospital, Harvard Medical School, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Transplantation Research Center, Brigham and Women's Hospital, Harvard Medical School, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.489300012588501,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.489300012588501,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.28780001401901245,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.10930000245571136,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/toll-like-receptor-signaling","display_name":"Toll-like receptor signaling","score":0.8579999804496765},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.8389999866485596},{"id":"https://openalex.org/keywords/il-17","display_name":"IL-17","score":1.0},{"id":"https://openalex.org/keywords/graft-rejection","display_name":"graft rejection","score":0.9509999752044678},{"id":"https://openalex.org/keywords/allograft-rejection","display_name":"allograft rejection","score":0.6320000290870667},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.6029999852180481},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.40400001406669617}],"concepts":[{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.37735533714294434},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33094531297683716},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32999029755592346},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.32270753383636475},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2955006957054138}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3410/f.1161031.621490","doi":"https://doi.org/10.3410/f.1161031.621490","is_oa":false,"landing_page_url":"https://doi.org/10.3410/f.1161031.621490","pdf_url":null,"source":{"id":"https://openalex.org/S4363604054","display_name":"Faculty Opinions \u2013 Post-Publication Peer Review of the Biomedical Literature","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Faculty Opinions \u2013 Post-Publication Peer Review of the Biomedical Literature","raw_type":"dataset"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7246000170707703,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.4300000071525574,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1835460549"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2022-05-12T00:00:00"}