{"id":"https://openalex.org/W4237970541","doi":"https://doi.org/10.26434/chemrxiv.14595654.v2","title":"Label-Free Plasmonic Biosensor for Rapid, Quantitative, and Highly Sensitive COVID-19 Serology: Implementation and Clinical Validation","display_name":"Label-Free Plasmonic Biosensor for Rapid, Quantitative, and Highly Sensitive COVID-19 Serology: Implementation and Clinical Validation","publication_year":2021,"publication_date":"2021-06-04","ids":{"openalex":"https://openalex.org/W4237970541","doi":"https://doi.org/10.26434/chemrxiv.14595654.v2"},"language":"en","primary_location":{"id":"doi:10.26434/chemrxiv.14595654.v2","doi":"https://doi.org/10.26434/chemrxiv.14595654.v2","is_oa":true,"landing_page_url":"https://doi.org/10.26434/chemrxiv.14595654.v2","pdf_url":"https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/60c759f80f50db1a60398783/original/label-free-plasmonic-biosensor-for-rapid-quantitative-and-highly-sensitive-covid-19-serology-implementation-and-clinical-validation.pdf","source":{"id":"https://openalex.org/S4393918830","display_name":"ChemRxiv","issn_l":"2573-2293","issn":["2573-2293"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/60c759f80f50db1a60398783/original/label-free-plasmonic-biosensor-for-rapid-quantitative-and-highly-sensitive-covid-19-serology-implementation-and-clinical-validation.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064210128","display_name":"Olalla Calvo-Lozano","orcid":"https://orcid.org/0000-0001-5486-2237","observed_orcids":["https://orcid.org/0000-0001-5486-2237"]},"institutions":[{"id":"https://openalex.org/I4210093216","display_name":"Institut Catal\u00e0 de Nanoci\u00e8ncia i Nanotecnologia","ror":"https://ror.org/00k1qja49","country_code":"ES","type":"facility","lineage":["https://openalex.org/I123044942","https://openalex.org/I134820265","https://openalex.org/I4210093216","https://openalex.org/I4210132884","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210105141","display_name":"Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine","ror":"https://ror.org/01gm5f004","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210105141"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Olalla Calvo-Lozano","raw_affiliation_strings":[". Nanobiosensors and Bioanalytical Applications Group (NanoB2A), Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and BIST, Campus UAB, 08193 Bellaterra, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Nanobiosensors and Bioanalytical Applications Group (NanoB2A), Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and BIST, Campus UAB, 08193 Bellaterra, Barcelona, Spain","institution_ids":["https://openalex.org/I4210093216","https://openalex.org/I4210105141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063242380","display_name":"MIquel Sierra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210093216","display_name":"Institut Catal\u00e0 de Nanoci\u00e8ncia i Nanotecnologia","ror":"https://ror.org/00k1qja49","country_code":"ES","type":"facility","lineage":["https://openalex.org/I123044942","https://openalex.org/I134820265","https://openalex.org/I4210093216","https://openalex.org/I4210132884","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210105141","display_name":"Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine","ror":"https://ror.org/01gm5f004","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210105141"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"MIquel Sierra","raw_affiliation_strings":[". Nanobiosensors and Bioanalytical Applications Group (NanoB2A), Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and BIST, Campus UAB, 08193 Bellaterra, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Nanobiosensors and Bioanalytical Applications Group (NanoB2A), Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and BIST, Campus UAB, 08193 Bellaterra, Barcelona, Spain","institution_ids":["https://openalex.org/I4210093216","https://openalex.org/I4210105141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082176205","display_name":"Maria Soler","orcid":"https://orcid.org/0000-0001-7232-2277","observed_orcids":["https://orcid.org/0000-0001-7232-2277"]},"institutions":[{"id":"https://openalex.org/I4210093216","display_name":"Institut Catal\u00e0 de Nanoci\u00e8ncia i Nanotecnologia","ror":"https://ror.org/00k1qja49","country_code":"ES","type":"facility","lineage":["https://openalex.org/I123044942","https://openalex.org/I134820265","https://openalex.org/I4210093216","https://openalex.org/I4210132884","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210105141","display_name":"Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine","ror":"https://ror.org/01gm5f004","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210105141"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Maria Soler","raw_affiliation_strings":[". Nanobiosensors and Bioanalytical Applications Group (NanoB2A), Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and BIST, Campus UAB, 08193 Bellaterra, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Nanobiosensors and Bioanalytical Applications Group (NanoB2A), Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and BIST, Campus UAB, 08193 Bellaterra, Barcelona, Spain","institution_ids":["https://openalex.org/I4210093216","https://openalex.org/I4210105141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073505057","display_name":"M.\u2010Carmen Est\u00e9vez","orcid":"https://orcid.org/0000-0003-3694-7186","observed_orcids":["https://orcid.org/0000-0003-3694-7186"]},"institutions":[{"id":"https://openalex.org/I4210093216","display_name":"Institut Catal\u00e0 de Nanoci\u00e8ncia i Nanotecnologia","ror":"https://ror.org/00k1qja49","country_code":"ES","type":"facility","lineage":["https://openalex.org/I123044942","https://openalex.org/I134820265","https://openalex.org/I4210093216","https://openalex.org/I4210132884","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M.-Carmen Estevez","raw_affiliation_strings":["Catalan Institute of Nanoscience and Nanotechnology (ICN2)"],"raw_orcid":"https://orcid.org/0000-0003-3694-7186","affiliations":[{"raw_affiliation_string":"Catalan Institute of Nanoscience and Nanotechnology (ICN2)","institution_ids":["https://openalex.org/I4210093216"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068665684","display_name":"Luis Chiscano\u2010Cam\u00f3n","orcid":"https://orcid.org/0000-0003-0037-0610","observed_orcids":["https://orcid.org/0000-0003-0037-0610"]},"institutions":[{"id":"https://openalex.org/I4210127641","display_name":"Vall d'Hebron Hospital Universitari","ror":"https://ror.org/03ba28x55","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I157913058","https://openalex.org/I4210127641","https://openalex.org/I4210153292"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"luis Chiscano-camon","raw_affiliation_strings":["'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain","institution_ids":["https://openalex.org/I4210127641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064817943","display_name":"Adolfo Ruiz-Sanmart\u00edn","orcid":"https://orcid.org/0000-0001-5587-5419","observed_orcids":["https://orcid.org/0000-0001-5587-5419"]},"institutions":[{"id":"https://openalex.org/I4210102407","display_name":"Vall d'Hebron Institut de Recerca","ror":"https://ror.org/01d5vx451","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210102407","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210127641","display_name":"Vall d'Hebron Hospital Universitari","ror":"https://ror.org/03ba28x55","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I157913058","https://openalex.org/I4210127641","https://openalex.org/I4210153292"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Adolfo Ruiz-Sanmart\u00edn","raw_affiliation_strings":[". Intensive Care Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain","Shock, Organ Dysfunction and Resuscitation Research Group, Vall d'Hebron Research Institute (VHIR), Vall"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Intensive Care Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain","institution_ids":["https://openalex.org/I4210127641"]},{"raw_affiliation_string":"Shock, Organ Dysfunction and Resuscitation Research Group, Vall d'Hebron Research Institute (VHIR), Vall","institution_ids":["https://openalex.org/I4210102407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077547848","display_name":"Juan Carlos Ruiz\u2010Rodr\u00edguez","orcid":"https://orcid.org/0000-0001-7392-8617","observed_orcids":["https://orcid.org/0000-0001-7392-8617"]},"institutions":[{"id":"https://openalex.org/I4210102407","display_name":"Vall d'Hebron Institut de Recerca","ror":"https://ror.org/01d5vx451","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210102407","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210127641","display_name":"Vall d'Hebron Hospital Universitari","ror":"https://ror.org/03ba28x55","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I157913058","https://openalex.org/I4210127641","https://openalex.org/I4210153292"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Juan Carlos Ruiz-Rodriguez","raw_affiliation_strings":[". Intensive Care Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain","Shock, Organ Dysfunction and Resuscitation Research Group, Vall d'Hebron Research Institute (VHIR), Vall"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Intensive Care Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain","institution_ids":["https://openalex.org/I4210127641"]},{"raw_affiliation_string":"Shock, Organ Dysfunction and Resuscitation Research Group, Vall d'Hebron Research Institute (VHIR), Vall","institution_ids":["https://openalex.org/I4210102407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033820862","display_name":"Ricard Ferrer","orcid":"https://orcid.org/0000-0002-4859-4747","observed_orcids":["https://orcid.org/0000-0002-4859-4747","https://orcid.org/0000-0002-0392-3631"]},"institutions":[{"id":"https://openalex.org/I4210102407","display_name":"Vall d'Hebron Institut de Recerca","ror":"https://ror.org/01d5vx451","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210102407","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210127641","display_name":"Vall d'Hebron Hospital Universitari","ror":"https://ror.org/03ba28x55","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I157913058","https://openalex.org/I4210127641","https://openalex.org/I4210153292"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Ricard Ferrer","raw_affiliation_strings":[". Intensive Care Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain","Shock, Organ Dysfunction and Resuscitation Research Group, Vall d'Hebron Research Institute (VHIR), Vall"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Intensive Care Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain","institution_ids":["https://openalex.org/I4210127641"]},{"raw_affiliation_string":"Shock, Organ Dysfunction and Resuscitation Research Group, Vall d'Hebron Research Institute (VHIR), Vall","institution_ids":["https://openalex.org/I4210102407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023758673","display_name":"Juan Jos\u00e9 Gonz\u00e1lez\u2010L\u00f3pez","orcid":"https://orcid.org/0000-0003-2419-5909","observed_orcids":["https://orcid.org/0000-0003-2419-5909"]},"institutions":[{"id":"https://openalex.org/I123044942","display_name":"Universitat Aut\u00f2noma de Barcelona","ror":"https://ror.org/052g8jq94","country_code":"ES","type":"education","lineage":["https://openalex.org/I123044942"]},{"id":"https://openalex.org/I4210102407","display_name":"Vall d'Hebron Institut de Recerca","ror":"https://ror.org/01d5vx451","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210102407","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210127641","display_name":"Vall d'Hebron Hospital Universitari","ror":"https://ror.org/03ba28x55","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I157913058","https://openalex.org/I4210127641","https://openalex.org/I4210153292"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Juan Jos\u00e9 Gonz\u00e1lez-L\u00f3pez","raw_affiliation_strings":[". Clinical Microbiology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129,08035, Barcelona, Spain",". Department of Genetics and Microbiology, Universitat Aut\u00f2noma de Barcelona, Pla\u00e7a C\u00edvica, 08193 Bellaterra, Barcelona, Spain",". Intensive Care Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain",". Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain","Shock, Organ Dysfunction and Resuscitation Research Group, Vall d'Hebron Research Institute (VHIR), Vall"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Clinical Microbiology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129,08035, Barcelona, Spain","institution_ids":["https://openalex.org/I4210127641"]},{"raw_affiliation_string":". Department of Genetics and Microbiology, Universitat Aut\u00f2noma de Barcelona, Pla\u00e7a C\u00edvica, 08193 Bellaterra, Barcelona, Spain","institution_ids":["https://openalex.org/I123044942"]},{"raw_affiliation_string":". Intensive Care Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain","institution_ids":["https://openalex.org/I4210127641"]},{"raw_affiliation_string":". Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain","institution_ids":["https://openalex.org/I4210102407"]},{"raw_affiliation_string":"Shock, Organ Dysfunction and Resuscitation Research Group, Vall d'Hebron Research Institute (VHIR), Vall","institution_ids":["https://openalex.org/I4210102407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015284610","display_name":"Juliana Esperalba","orcid":"https://orcid.org/0000-0003-1326-1341","observed_orcids":["https://orcid.org/0000-0003-1326-1341"]},"institutions":[{"id":"https://openalex.org/I4210102407","display_name":"Vall d'Hebron Institut de Recerca","ror":"https://ror.org/01d5vx451","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210102407","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210127641","display_name":"Vall d'Hebron Hospital Universitari","ror":"https://ror.org/03ba28x55","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I157913058","https://openalex.org/I4210127641","https://openalex.org/I4210153292"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Juliana Esperalba","raw_affiliation_strings":[". Clinical Microbiology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129,08035, Barcelona, Spain",". Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Clinical Microbiology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129,08035, Barcelona, Spain","institution_ids":["https://openalex.org/I4210127641"]},{"raw_affiliation_string":". Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain","institution_ids":["https://openalex.org/I4210102407","https://openalex.org/I4210127641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064077762","display_name":"Candela Fern\u00e1ndez\u2010Naval","orcid":"https://orcid.org/0000-0002-5584-3537","observed_orcids":["https://orcid.org/0000-0002-5584-3537"]},"institutions":[{"id":"https://openalex.org/I4210102407","display_name":"Vall d'Hebron Institut de Recerca","ror":"https://ror.org/01d5vx451","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210102407","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210127641","display_name":"Vall d'Hebron Hospital Universitari","ror":"https://ror.org/03ba28x55","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I157913058","https://openalex.org/I4210127641","https://openalex.org/I4210153292"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Candela fernandez-naval","raw_affiliation_strings":[". Clinical Microbiology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129,08035, Barcelona, Spain",". Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Clinical Microbiology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129,08035, Barcelona, Spain","institution_ids":["https://openalex.org/I4210127641"]},{"raw_affiliation_string":". Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain","institution_ids":["https://openalex.org/I4210102407","https://openalex.org/I4210127641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018328234","display_name":"Leticia Bueno","orcid":"https://orcid.org/0000-0002-2392-8763","observed_orcids":["https://orcid.org/0000-0002-2392-8763"]},"institutions":[{"id":"https://openalex.org/I4210099160","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias","ror":"https://ror.org/0119pby33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210099160","https://openalex.org/I4210115082","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"leticia Bueno","raw_affiliation_strings":[". Cellex Laboratory, CiberRes (Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias, 06/06/0028), Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Carrer de Rosell\u00f3 149, 08036 Barcelona, Spain",". Department of Pneumology, Thorax Institute, Hospital Clinic of Barcelona, Carrer de Villarroel, 170, 08036 Barcelona, Spain",". School of Medicine, University of Barcelona, Carrer de Casanova, 143, 08036 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Cellex Laboratory, CiberRes (Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias, 06/06/0028), Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Carrer de Rosell\u00f3 149, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I4210099160","https://openalex.org/I4210160192"]},{"raw_affiliation_string":". Department of Pneumology, Thorax Institute, Hospital Clinic of Barcelona, Carrer de Villarroel, 170, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]},{"raw_affiliation_string":". School of Medicine, University of Barcelona, Carrer de Casanova, 143, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004815539","display_name":"Rub\u00e9n L\u00f3pez-Aladid","orcid":"https://orcid.org/0000-0002-4976-6571","observed_orcids":["https://orcid.org/0000-0002-4976-6571"]},"institutions":[{"id":"https://openalex.org/I4210099160","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias","ror":"https://ror.org/0119pby33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210099160","https://openalex.org/I4210115082","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Rub\u00e9n L\u00f3pez-Aladid","raw_affiliation_strings":[". Cellex Laboratory, CiberRes (Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias, 06/06/0028), Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Carrer de Rosell\u00f3 149, 08036 Barcelona, Spain",". Department of Pneumology, Thorax Institute, Hospital Clinic of Barcelona, Carrer de Villarroel, 170, 08036 Barcelona, Spain",". School of Medicine, University of Barcelona, Carrer de Casanova, 143, 08036 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Cellex Laboratory, CiberRes (Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias, 06/06/0028), Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Carrer de Rosell\u00f3 149, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I4210099160","https://openalex.org/I4210160192"]},{"raw_affiliation_string":". Department of Pneumology, Thorax Institute, Hospital Clinic of Barcelona, Carrer de Villarroel, 170, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]},{"raw_affiliation_string":". School of Medicine, University of Barcelona, Carrer de Casanova, 143, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100752902","display_name":"Anton\u00ed Torres","orcid":"https://orcid.org/0000-0002-8643-2167","observed_orcids":["https://orcid.org/0000-0002-8643-2167","https://orcid.org/0000-0002-5470-2978"]},"institutions":[{"id":"https://openalex.org/I4210099160","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias","ror":"https://ror.org/0119pby33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210099160","https://openalex.org/I4210115082","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Antoni Torres","raw_affiliation_strings":[". Cellex Laboratory, CiberRes (Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias, 06/06/0028), Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Carrer de Rosell\u00f3 149, 08036 Barcelona, Spain",". Department of Pneumology, Thorax Institute, Hospital Clinic of Barcelona, Carrer de Villarroel, 170, 08036 Barcelona, Spain",". School of Medicine, University of Barcelona, Carrer de Casanova, 143, 08036 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Cellex Laboratory, CiberRes (Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias, 06/06/0028), Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Carrer de Rosell\u00f3 149, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I4210099160","https://openalex.org/I4210160192"]},{"raw_affiliation_string":". Department of Pneumology, Thorax Institute, Hospital Clinic of Barcelona, Carrer de Villarroel, 170, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]},{"raw_affiliation_string":". School of Medicine, University of Barcelona, Carrer de Casanova, 143, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073753580","display_name":"Laia Fern\u00e1ndez\u2010Barat","orcid":"https://orcid.org/0000-0001-7528-9636","observed_orcids":["https://orcid.org/0000-0001-7528-9636"]},"institutions":[{"id":"https://openalex.org/I4210099160","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias","ror":"https://ror.org/0119pby33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210099160","https://openalex.org/I4210115082","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Laia Fern\u00e1ndez-Barat","raw_affiliation_strings":[". Cellex Laboratory, CiberRes (Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias, 06/06/0028), Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Carrer de Rosell\u00f3 149, 08036 Barcelona, Spain",". Department of Pneumology, Thorax Institute, Hospital Clinic of Barcelona, Carrer de Villarroel, 170, 08036 Barcelona, Spain",". School of Medicine, University of Barcelona, Carrer de Casanova, 143, 08036 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Cellex Laboratory, CiberRes (Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias, 06/06/0028), Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Carrer de Rosell\u00f3 149, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I4210099160","https://openalex.org/I4210160192"]},{"raw_affiliation_string":". Department of Pneumology, Thorax Institute, Hospital Clinic of Barcelona, Carrer de Villarroel, 170, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097"]},{"raw_affiliation_string":". School of Medicine, University of Barcelona, Carrer de Casanova, 143, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054622312","display_name":"Sarah Attoumani","orcid":"https://orcid.org/0000-0002-4878-6052","observed_orcids":["https://orcid.org/0000-0002-4878-6052"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210166444","display_name":"Institut de Recherche pour le D\u00e9veloppement","ror":"https://ror.org/05q3vnk25","country_code":"FR","type":"government","lineage":["https://openalex.org/I2802818602","https://openalex.org/I4210090127","https://openalex.org/I4210131494","https://openalex.org/I4210166444"]},{"id":"https://openalex.org/I4405274755","display_name":"Unit\u00e9 des Virus Emergents","ror":"https://ror.org/029fc9d45","country_code":"FR","type":"facility","lineage":["https://openalex.org/I21491767","https://openalex.org/I4405274755"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sarah Attoumani","raw_affiliation_strings":[". Unit\u00e9 des Virus \u00c9mergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Unit\u00e9 des Virus \u00c9mergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210166444","https://openalex.org/I4405274755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005113560","display_name":"R\u00e9mi N. Charrel","orcid":"https://orcid.org/0000-0002-7675-8251","observed_orcids":["https://orcid.org/0000-0002-7675-8251"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210166444","display_name":"Institut de Recherche pour le D\u00e9veloppement","ror":"https://ror.org/05q3vnk25","country_code":"FR","type":"government","lineage":["https://openalex.org/I2802818602","https://openalex.org/I4210090127","https://openalex.org/I4210131494","https://openalex.org/I4210166444"]},{"id":"https://openalex.org/I4405274755","display_name":"Unit\u00e9 des Virus Emergents","ror":"https://ror.org/029fc9d45","country_code":"FR","type":"facility","lineage":["https://openalex.org/I21491767","https://openalex.org/I4405274755"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Remi Charrel","raw_affiliation_strings":[". Unit\u00e9 des Virus \u00c9mergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Unit\u00e9 des Virus \u00c9mergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210166444","https://openalex.org/I4405274755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090442657","display_name":"Bruno Coutard","orcid":"https://orcid.org/0000-0002-2859-7123","observed_orcids":["https://orcid.org/0000-0002-2859-7123"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210166444","display_name":"Institut de Recherche pour le D\u00e9veloppement","ror":"https://ror.org/05q3vnk25","country_code":"FR","type":"government","lineage":["https://openalex.org/I2802818602","https://openalex.org/I4210090127","https://openalex.org/I4210131494","https://openalex.org/I4210166444"]},{"id":"https://openalex.org/I4405274755","display_name":"Unit\u00e9 des Virus Emergents","ror":"https://ror.org/029fc9d45","country_code":"FR","type":"facility","lineage":["https://openalex.org/I21491767","https://openalex.org/I4405274755"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bruno Coutard","raw_affiliation_strings":[". Unit\u00e9 des Virus \u00c9mergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Unit\u00e9 des Virus \u00c9mergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210166444","https://openalex.org/I4405274755"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057714878","display_name":"Laura M. Lechuga","orcid":"https://orcid.org/0000-0001-5187-5358","observed_orcids":["https://orcid.org/0000-0001-5187-5358"]},"institutions":[{"id":"https://openalex.org/I4210093216","display_name":"Institut Catal\u00e0 de Nanoci\u00e8ncia i Nanotecnologia","ror":"https://ror.org/00k1qja49","country_code":"ES","type":"facility","lineage":["https://openalex.org/I123044942","https://openalex.org/I134820265","https://openalex.org/I4210093216","https://openalex.org/I4210132884","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210105141","display_name":"Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine","ror":"https://ror.org/01gm5f004","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210105141"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Laura M. Lechuga","raw_affiliation_strings":[". Nanobiosensors and Bioanalytical Applications Group (NanoB2A), Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and BIST, Campus UAB, 08193 Bellaterra, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Nanobiosensors and Bioanalytical Applications Group (NanoB2A), Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and BIST, Campus UAB, 08193 Bellaterra, Barcelona, Spain","institution_ids":["https://openalex.org/I4210093216","https://openalex.org/I4210105141"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":13,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11754","display_name":"SARS-CoV-2 detection and testing","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11754","display_name":"SARS-CoV-2 detection and testing","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.008299999870359898,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/covid-19-serology","display_name":"COVID-19 serology","score":0.9660000205039978},{"id":"https://openalex.org/keywords/sars-cov-2-antibodies","display_name":"SARS-CoV-2 antibodies","score":0.9589999914169312},{"id":"https://openalex.org/keywords/surface-plasmon-resonance-biosensor","display_name":"surface plasmon resonance biosensor","score":0.9369999766349792},{"id":"https://openalex.org/keywords/label-free-biosensing","display_name":"label-free biosensing","score":0.7099999785423279},{"id":"https://openalex.org/keywords/rapid-antibody-detection","display_name":"rapid antibody detection","score":0.5659999847412109},{"id":"https://openalex.org/keywords/nucleocapsid-protein","display_name":"nucleocapsid protein","score":0.9599999785423279},{"id":"https://openalex.org/keywords/portable-biosensor","display_name":"portable biosensor","score":0.5410000085830688},{"id":"https://openalex.org/keywords/clinical-validation","display_name":"clinical validation","score":0.6909999847412109},{"id":"https://openalex.org/keywords/antibody-quantification","display_name":"antibody quantification","score":0.6549999713897705},{"id":"https://openalex.org/keywords/decentralized-diagnostics","display_name":"decentralized diagnostics","score":0.44600000977516174}],"concepts":[{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.8006038665771484},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.596060037612915},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5358278751373291},{"id":"https://openalex.org/C87892846","wikidata":"https://www.wikidata.org/wiki/Q864256","display_name":"Biochip","level":2,"score":0.5243675708770752},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.505814790725708},{"id":"https://openalex.org/C106847996","wikidata":"https://www.wikidata.org/wiki/Q898756","display_name":"Surface plasmon resonance","level":3,"score":0.4769496023654938},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.43717271089553833},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33174335956573486},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.26216500997543335},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2230883538722992},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.16849082708358765},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.05925390124320984}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.26434/chemrxiv.14595654.v2","doi":"https://doi.org/10.26434/chemrxiv.14595654.v2","is_oa":true,"landing_page_url":"https://doi.org/10.26434/chemrxiv.14595654.v2","pdf_url":"https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/60c759f80f50db1a60398783/original/label-free-plasmonic-biosensor-for-rapid-quantitative-and-highly-sensitive-covid-19-serology-implementation-and-clinical-validation.pdf","source":{"id":"https://openalex.org/S4393918830","display_name":"ChemRxiv","issn_l":"2573-2293","issn":["2573-2293"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/14595654","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/preprint/Label-Free_Plasmonic_Biosensor_for_Rapid_Quantitative_and_Highly_Sensitive_COVID-19_Serology_Implementation_and_Clinical_Validation/14595654","pdf_url":null,"source":{"id":"https://openalex.org/S7407051385","display_name":"Royal College of Surgeons in Ireland","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I142762351","host_organization_name":"Royal College of Surgeons in Ireland","host_organization_lineage":["https://openalex.org/I142762351"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.26434/chemrxiv.14595654.v2","doi":"https://doi.org/10.26434/chemrxiv.14595654.v2","is_oa":true,"landing_page_url":"https://doi.org/10.26434/chemrxiv.14595654.v2","pdf_url":"https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/60c759f80f50db1a60398783/original/label-free-plasmonic-biosensor-for-rapid-quantitative-and-highly-sensitive-covid-19-serology-implementation-and-clinical-validation.pdf","source":{"id":"https://openalex.org/S4393918830","display_name":"ChemRxiv","issn_l":"2573-2293","issn":["2573-2293"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1288213089","display_name":null,"funder_award_id":"SEV\u20102017\u20100706","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"},{"id":"https://openalex.org/G1573420984","display_name":null,"funder_award_id":"RD16/0016/0003","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"},{"id":"https://openalex.org/G1694499074","display_name":null,"funder_award_id":"REIPI RD16/0016","funder_id":"https://openalex.org/F4320334923","funder_display_name":"Instituto de Salud Carlos III"},{"id":"https://openalex.org/G2567209517","display_name":null,"funder_award_id":"RD16/0016","funder_id":"https://openalex.org/F4320334923","funder_display_name":"Instituto de Salud Carlos III"},{"id":"https://openalex.org/G2913093573","display_name":null,"funder_award_id":"SEV-2017-0706","funder_id":"https://openalex.org/F4320321505","funder_display_name":"Generalitat de Catalunya"},{"id":"https://openalex.org/G3213851577","display_name":"Combating 2019-nCoV: Advanced Nanobiosensing platforms for POC global diagnostics and surveillance","funder_award_id":"101003544","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3531243981","display_name":null,"funder_award_id":"REIPI RD16/0016/0003","funder_id":"https://openalex.org/F4320334923","funder_display_name":"Instituto de Salud Carlos III"},{"id":"https://openalex.org/G3944635923","display_name":null,"funder_award_id":"871029","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G4097513397","display_name":"European Virus Archive GLOBAL","funder_award_id":"871029","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4193446334","display_name":null,"funder_award_id":"2013-2016","funder_id":"https://openalex.org/F4320334923","funder_display_name":"Instituto de Salud Carlos III"},{"id":"https://openalex.org/G426068792","display_name":null,"funder_award_id":"BES-2017-080527","funder_id":"https://openalex.org/F4320335598","funder_display_name":"Agencia Estatal de Investigaci\u00f3n"},{"id":"https://openalex.org/G4333900429","display_name":null,"funder_award_id":"2013-2016","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G434337789","display_name":null,"funder_award_id":"HORIZON2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4937468798","display_name":null,"funder_award_id":"H2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4980280128","display_name":null,"funder_award_id":"101003544","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G5008517179","display_name":"Scalable, point-of-care and label free microarray platform for rapid detection of Sepsis","funder_award_id":"644956","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5278215002","display_name":null,"funder_award_id":"I+D+i 2013-2016","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"},{"id":"https://openalex.org/G574523618","display_name":null,"funder_award_id":"644956","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G6122222817","display_name":null,"funder_award_id":"COVID-19","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G6436741698","display_name":null,"funder_award_id":"RD16/0016/0003","funder_id":"https://openalex.org/F4320334923","funder_display_name":"Instituto de Salud Carlos III"},{"id":"https://openalex.org/G6466088583","display_name":null,"funder_award_id":"SEV\u20102017\u20100706","funder_id":"https://openalex.org/F4320335598","funder_display_name":"Agencia Estatal de Investigaci\u00f3n"},{"id":"https://openalex.org/G683931746","display_name":null,"funder_award_id":"H2020","funder_id":"https://openalex.org/F4320335598","funder_display_name":"Agencia Estatal de Investigaci\u00f3n"},{"id":"https://openalex.org/G7126188449","display_name":null,"funder_award_id":"BES-2017-080527","funder_id":"https://openalex.org/F4320338080","funder_display_name":"European Social Fund"},{"id":"https://openalex.org/G847393302","display_name":null,"funder_award_id":"2016-78515-R","funder_id":"https://openalex.org/F4320335598","funder_display_name":"Agencia Estatal de Investigaci\u00f3n"},{"id":"https://openalex.org/G8824911526","display_name":null,"funder_award_id":"H2020","funder_id":"https://openalex.org/F4320334923","funder_display_name":"Instituto de Salud Carlos III"}],"funders":[{"id":"https://openalex.org/F4320315803","display_name":"Centres de Recerca de Catalunya","ror":"https://ror.org/01bkbaq61"},{"id":"https://openalex.org/F4320317176","display_name":"Institut Catal\u00e0 de Nanoci\u00e8ncia i Nanotecnologia","ror":"https://ror.org/00k1qja49"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321505","display_name":"Generalitat de Catalunya","ror":"https://ror.org/01bg62x04"},{"id":"https://openalex.org/F4320322930","display_name":"Ministerio de Ciencia e Innovaci\u00f3n","ror":null},{"id":"https://openalex.org/F4320327451","display_name":"Fundaci\u00f3 Institut de Recerca Hospital Universitari Vall d\u2019Hebron","ror":null},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320334923","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886"},{"id":"https://openalex.org/F4320335598","display_name":"Agencia Estatal de Investigaci\u00f3n","ror":"https://ror.org/003x0zc53"},{"id":"https://openalex.org/F4320338080","display_name":"European Social Fund","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4237970541.pdf","grobid_xml":"https://content.openalex.org/works/W4237970541.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W1961523492","https://openalex.org/W2020685474","https://openalex.org/W2027195370","https://openalex.org/W2030962930","https://openalex.org/W2057286595","https://openalex.org/W2069160844","https://openalex.org/W2115484790","https://openalex.org/W2136780141","https://openalex.org/W2166127386","https://openalex.org/W2345666487","https://openalex.org/W2567163077","https://openalex.org/W2887698117","https://openalex.org/W2999535351","https://openalex.org/W3012550011","https://openalex.org/W3013985547","https://openalex.org/W3014721277","https://openalex.org/W3014902927","https://openalex.org/W3017186084","https://openalex.org/W3018638113","https://openalex.org/W3019765297","https://openalex.org/W3020220400","https://openalex.org/W3021161367","https://openalex.org/W3021590963","https://openalex.org/W3024006735","https://openalex.org/W3024289893","https://openalex.org/W3024607230","https://openalex.org/W3025320502","https://openalex.org/W3029201461","https://openalex.org/W3034680516","https://openalex.org/W3036117095","https://openalex.org/W3037008296","https://openalex.org/W3038707046","https://openalex.org/W3039328844","https://openalex.org/W3041821205","https://openalex.org/W3042969080","https://openalex.org/W3043813948","https://openalex.org/W3048322686","https://openalex.org/W3048917590","https://openalex.org/W3081055927","https://openalex.org/W3091201856","https://openalex.org/W3091913409","https://openalex.org/W3092136311","https://openalex.org/W3094814522","https://openalex.org/W3101377389","https://openalex.org/W3113228067","https://openalex.org/W3114567452"],"related_works":["https://openalex.org/W3185190449","https://openalex.org/W4390490208","https://openalex.org/W4220806269","https://openalex.org/W3091201856","https://openalex.org/W3092617095","https://openalex.org/W3168894630","https://openalex.org/W4392972312","https://openalex.org/W4365452894","https://openalex.org/W4321766575","https://openalex.org/W4296193075"],"abstract_inverted_index":{"Serological":[0],"tests":[1],"are":[2,182],"essential":[3],"for":[4,14,21,154,244,259,266],"the":[5,48,126,144,171,185,200,223,260,267],"control":[6],"and":[7,16,24,55,71,85,90,116,151,217,228,240,246,256,265],"management":[8,261],"of":[9,50,118,128,157,262,269,278],"COVID-19":[10,29,191,215,248,263],"pandemic,":[11],"not":[12],"only":[13],"current":[15],"historical":[17],"diagnostics":[18,242],"but":[19,74],"especially":[20],"surveillance,":[22],"epidemiological,":[23],"acquired":[25],"immunity":[26],"studies.":[27],"Clinical":[28],"serology":[30,165,249],"is":[31],"routinely":[32],"performed":[33],"by":[34],"enzymatic":[35],"or":[36,41,275],"chemiluminescence":[37],"immunoassays":[38],"(i.e.,":[39],"ELISA":[40],"CLIA),":[42],"which":[43,181],"provide":[44],"good":[45],"sensitivities":[46],"at":[47,254],"expense":[49],"relatively":[51,82],"long":[52],"turnaround":[53],"times":[54],"specialized":[56],"laboratory":[57,255],"settings.":[58],"Rapid":[59],"serological":[60,94],"tests,":[61],"based":[62,100],"on":[63,101],"lateral":[64],"flow":[65],"assays,":[66],"have":[67,88,208],"also":[68,196],"been":[69,197],"developed":[70,89],"widely":[72],"commercialized,":[73],"they":[75],"suffer":[76],"from":[77],"limited":[78],"reliability":[79],"due":[80],"to":[81,250],"low":[83,172],"sensitivity":[84,226],"specificity.":[86],"We":[87,207],"validated":[91],"a":[92,109,138,211],"direct":[93],"biosensor":[95,107,135,234],"assay":[96,166,194],"employing":[97,176,199],"proprietary":[98],"technology":[99],"Surface":[102],"Plasmon":[103],"Resonance":[104],"(SPR).":[105],"The":[106,132,163,193],"offers":[108],"rapid":[110,245],"-less":[111],"than":[112],"15":[113],"min-":[114],"identification":[115],"quantification":[117],"SARS-CoV-2":[119],"antibodies":[120,159,178],"directly":[121],"in":[122,170,190,276],"clinical":[123,212],"samples,":[124],"without":[125],"need":[127],"any":[129],"signal":[130],"amplification.":[131],"portable":[133],"plasmonic":[134],"device":[136,235],"employs":[137],"custom-designed":[139],"multi-antigen":[140],"sensor":[141],"biochip,":[142],"combining":[143],"two":[145],"main":[146],"viral":[147],"antigens":[148],"(RBD":[149],"peptide":[150],"N":[152],"protein),":[153],"simultaneous":[155],"detection":[156,168],"human":[158],"targeting":[160],"both":[161,253],"antigens.":[162],"SPR":[164],"reaches":[167],"limits":[169],"ng":[173],"mL-1":[174],"range":[175],"polyclonal":[177],"as":[179,236],"standard,":[180],"well":[183],"below":[184],"commonly":[186],"detected":[187],"antibody":[188],"levels":[189],"patients.":[192],"has":[195],"implemented":[198],"first":[201],"WHO":[202],"approved":[203],"anti-SARS-CoV-2":[204],"immunoglobulin":[205],"standard.":[206],"carried":[209],"out":[210],"validation":[213],"with":[214],"positive":[216],"negative":[218],"samples":[219],"(n=120)":[220],"that":[221],"demonstrates":[222],"excellent":[224],"diagnostic":[225],"(99%)":[227],"specificity":[229],"(100%).":[230],"This":[231],"positions":[232],"our":[233],"an":[237],"accurate,":[238],"robust,":[239],"easy-to-use":[241],"tool":[243],"reliable":[247],"be":[251],"employed":[252],"decentralized":[257],"settings":[258],"patients":[264],"evaluation":[268],"immunological":[270],"status":[271],"during":[272],"vaccination,":[273],"treatment":[274],"front":[277],"emerging":[279],"variants.":[280]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2022-05-12T00:00:00"}